The application of Chinese medicine to novel drug discovery

Bibliography

• Jones DS, Podolsky SH, Greene JA. The burden of disease and the changing task of medicine. N Engl J Med 2012;366(25):2333-8
   PubMed Web of Science ®Google Scholar
• Pammolli F, Magazzini L, Riccaboni M. The productivity crisis in pharmaceutical R&D. Nat Rev Drug Discov 2011;10(6):428-38
   PubMed Web of Science ®Google Scholar
• Munos BH, Chin WW. How to revive breakthrough innovation in the pharmaceutical industry. Sci Transl Med 2011;3:89cm16
   PubMed Web of Science ®Google Scholar
• Sams-Dodd F. Target-based drug discovery: is something wrong? Drug Discov Today 2005;10(2):139-47
   PubMed Web of Science ®Google Scholar
• Hopkins AL. Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol 2008;4(11):682-90
   PubMed Web of Science ®Google Scholar
• Li JW-H, Vederas JC. Drug Discovery and Natural Products: end of an Era or an Endless Frontier? Science 2009;325(5937):161-5
   PubMed Web of Science ®Google Scholar
• Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod 2007;Mar70(3):461-77
   PubMed Web of Science ®Google Scholar
• Harvey AL. Natural products in drug discovery. Drug Discov Today 2008;13(19-20):894-901
   PubMed Web of Science ®Google Scholar
• Rishton GM. Natural products as a robust source of new drugs and drug leads: past successes and present day issues. Am J Cardiol 2008;101(10):S43-9
   PubMed Web of Science ®Google Scholar
• Verpoorte R. Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development. Drug Discov Today 1998;3(5):232-8
   Web of Science ®Google Scholar
• Newman DJ, Cragg GM, Snader KM. Natural products as sources of new drugs over the period 1981-2002. J Nat Prod 2003;66(7):1022-37
   PubMed Web of Science ®Google Scholar
• Littleton J. The future of plant drug discovery. Expert Opin Drug Discov 2007;2(5):673-83
   PubMed Web of Science ®Google Scholar
• Kinghorn AD, Chai H-b, Sung CK, The classical drug discovery approach to defining bioactive constituents of botanicals. Fitoterapia 2011;82(1):71-9
   PubMed Web of Science ®Google Scholar
• Clardy J, Walsh C. Lessons from natural molecules. Nature 2004;432(7019):829-37
   PubMed Web of Science ®Google Scholar
• Reynolds KA. Combinatorial biosynthesis: lesson learned from nature. Proc Natl Acad Sci USA 1998;95(22):12744-6
   PubMed Web of Science ®Google Scholar
• Wink M. Introduction: biochemistry, physiology and ecological functions of secondary metabolites. annual plant reviews volume 40: biochemistry of plant secondary metabolism. Wiley-Blackwell:Hoboken, New Jersey; 2010. p. 1-19
   Google Scholar
• Fabricant DS, Farnsworth NR. The value of plants used in traditional medicine for drug discovery. Environ Health Perspect 2001;109(Suppl 1):69-75
   PubMed Web of Science ®Google Scholar
• Wray S, Eisner DA, Allen DG. Two hundred years of the foxglove. Med Hist Suppl 1985(5):132-50
   PubMedGoogle Scholar
• Patwardhan B, Vaidya ADB, Chorghade M, Reverse pharmacology and systems approaches for drug discovery and development. Curr Bioactive Compounds 2008;4(4):201-12
   Google Scholar
• Miller LH, Su X. Artemisinin: discovery from the Chinese Herbal Garden. Cell 2011;146(6):855-8
   PubMed Web of Science ®Google Scholar
• Sivin N. University of Michigan. Center for Chinese Studies. Traditional medicine in contemporary China : a partial translation of Revised outline of Chinese medicine (1972) : with an introductory study on change in present day and early medicine. Center for Chinese Studies, University of Michigan; Ann Arbor: 1987
   Google Scholar
• Unschuld PU. Medicine in China: a history of ideas. University of California Press; Berkeley: 1985
   Google Scholar
• Xu X. The English-Chinese encyclopedia of practical traditional Chinese medicine. Higher Education Press; Beijing: 1991
   Google Scholar
• Porkert M. The theoretical foundations of Chinese medicine: systems of correspondence. MIT Press; Cambridge: 1974
   Google Scholar
• Chen Z, Sandercock P, Xie JX, Hospital management of acute ischemic stroke in China. J Stroke Cerebrovasc Dis 1997;6(5):361-7
   PubMedGoogle Scholar
• Chen F-P, Chen T-J, Kung Y-Y, Use frequency of traditional Chinese medicine in Taiwan. BMC Health Serv Res 2007;7:26
   PubMed Web of Science ®Google Scholar
• Chan TY, Chan JC, Tomlinson B, Chinese herbal medicines revisited: a Hong Kong perspective. Lancet 1993;342(8886-8887):1532-4
   PubMed Web of Science ®Google Scholar
• Unschuld PU. Medicine in China: a history of pharmaceutics. University of California Press; Berkeley: 1986
   Google Scholar
• Goldschmidt AM. The evolution of Chinese medicine : song dynasty, 960-1200. Routledge; London, New York: 2009
   Google Scholar
• Unschuld PU. Huang Di nei jing su wen: nature, knowledge, imagery in an ancient Chinese medical text, with an appendix, The doctrine of the five periods and six qi in the Huang Di nei jing su wen. University of California Press; Berkeley: 2003
   Google Scholar
• Pien cü, Unschuld PU. Nan-ching: the classic of difficult issues, with commentaries by Chinese and Japanese authors from the third through the twentieth century. University of California Press; Berkeley: 1986
   Google Scholar
• Taylor K. Chinese medicine in early communist China, 1945-63: a medicine of revolution. RoutledgeCurzon; London, New York: 2005
   Google Scholar
• Lu W-B. The modern scientific research on the theory of traditional chinese medicine. Anc Sci Life 1983;2(3):122-32
   PubMedGoogle Scholar
• Hou Z. Traditional chinese medicine making its mark on the world. Anc Sci Life 1987;7(2):90-8
   PubMedGoogle Scholar
• Chan K. Progress in traditional Chinese medicine. Trends Pharmacol Sci 1995;16(6):182-7
   PubMed Web of Science ®Google Scholar
• Chen KK, Schmidt CF. Ephedrine and related substances. The Williams & Wilkins Co; Baltimore: 1930
   Google Scholar
• Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China. English edition. Chemical Industry Press; Beijing, China: 2000
   Google Scholar
• State Administration of Traditional Chinese Materia Medica. Chinese materia medica. Shanghai Science and Technology Press: Shanghai, China 2005
   Google Scholar
• Sucher NJ. Insights from molecular investigations of traditional Chinese herbal stroke medicines: implications for neuroprotective epilepsy therapy. Epilepsy Behavior 2006;8(2):350-62
   PubMed Web of Science ®Google Scholar
• Wang Z, Liu J, Cheng Y, Fangjiomics: in search of effective and safe combination therapies. J Clin Pharmacol 2011;51(8):1132-51
   PubMed Web of Science ®Google Scholar
• Flower A, Witt C, Liu JP, Guidelines for randomised controlled trials investigating Chinese herbal medicine. J Ethnopharmocol 2012;140(3):550-4
   PubMed Web of Science ®Google Scholar
• Tang JL, Zhan SY, Ernst E. Review of randomised controlled trials of traditional Chinese medicine. Bmj 1999;319(7203):160-1
   PubMed Web of Science ®Google Scholar
• Wu T, Li Y, Bian Z, Randomized trials published in some Chinese journals: how many are randomized? Trials 2009;10(1):46
   PubMed Web of Science ®Google Scholar
• Hu J, Zhang J, Zhao W, Cochrane Systematic Reviews of Chinese Herbal Medicines: an Overview. PLoS One 2011;6(12):e28696
   PubMed Web of Science ®Google Scholar
• US National Library of Medicine National Institutes of Health. Available from: http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed 2012
   Google Scholar
• Roys CK. Chinese Medicine in America. Cal State J Med 1913;11(3):114-18
   PubMedGoogle Scholar
• Fan KW. Online research databases and journals of Chinese medicine. J Altern Complement Med 2004;10(6):1123-8
   PubMed Web of Science ®Google Scholar
• Zhou X, Peng Y, Liu B. Text mining for traditional Chinese medical knowledge discovery: a survey. J Biomed Inform 2010;43(4):650-60
   PubMed Web of Science ®Google Scholar
• Barlow DJ, Buriani A, Ehrman T, In-silico studies in Chinese herbal medicines' research: evaluation of in-silico methodologies and phytochemical data sources, and a review of research to date. J Ethnopharmacol 2012;140(3):526-34
   PubMed Web of Science ®Google Scholar
• Chen C. PLoS One: TCM Database@Taiwan: the world's largest traditional chinese medicine database for drug screening in Silico. PLoS One 2011;6(1):e15939
   PubMed Web of Science ®Google Scholar
• Ehrman TM, Barlow DJ, Hylands PJ. Phytochemical Databases of Chinese Herbal Constituents and Bioactive Plant Compounds with Known Target Specificities. J Chem Inf Model 2007;Mar2847(2):254-63
   PubMed Web of Science ®Google Scholar
• Shanghai TCM Data Center. Chinese Medicine Prescription Database (in Chinese). Available from: http://www.tcm120.com/1w2k/tcm_recipe.asp 2012
   Google Scholar
• Harris ESJ, Erickson SD, Tolopko AN, Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs. J Ethnopharmocol 2011;135(2):590-3
   PubMed Web of Science ®Google Scholar
• The Program for Collaborative Research in the Pharmaceutical Sciences (PCRPS) College of Pharmacy, University of Illinois at Chicago. NAPRALERT. Available from: http://www.napralert.org/2012
   Google Scholar
• Jiang M, Lu C, Zhang C, Syndrome differentiation in modern research of traditional Chinese medicine. J Ethnopharmocol 2012;140(3):634-42
   PubMed Web of Science ®Google Scholar
• Tao X, Wang X, Jia W. Using Chinese natural products for diabetes mellitus drug discovery and development. Expert Opin Drug Discov 2007;2(7):977-86
   PubMed Web of Science ®Google Scholar
• Efferth T, Li PCH, Konkimalla VSB, From traditional Chinese medicine to rational cancer therapy. Trends Mol Med 2007;Aug13(8):353-61
   PubMed Web of Science ®Google Scholar
• Gong X, Sucher NJ. Stroke therapy in traditional Chinese medicine (TCM): prospects for drug discovery and development. Trends Pharmacol Sci 1999;20(5):191-6
   PubMed Web of Science ®Google Scholar
• Ho Y-S, So K-F, Chang RC-C. Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia. Chin Med 2011;6(1):15
   PubMed Web of Science ®Google Scholar
• Wang Y, Huang L-q, Tang X-c, Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia. Acta Pharmacol Sin 2010;31(6):649-64
   PubMed Web of Science ®Google Scholar
• Qicheng F. Some current study and research approaches relating to the use of plants in the traditional Chinese medicine. J Ethnopharmocol 1980;2(1):57-63
   PubMed Web of Science ®Google Scholar
• Gertsch J. How scientific is the science in Ethnopharmocology? Historical perspectives and epistemological problems. J Ethnopharmocol 2009;122(2):177-83
   PubMed Web of Science ®Google Scholar
• Butterweck V, Nahrstedt A. What Is the Best Strategy for Preclinical Testing of Botanicals? A Critical Perspective. Planta Med 2012;78(08):747-54
   PubMed Web of Science ®Google Scholar
• Li X-J, Zhang H-Y. Synergy in natural medicines: implications for drug discovery. Trends Pharmacol Sci 2008;29(7):331-2
   PubMed Web of Science ®Google Scholar
• Zhao S, Iyengar R. Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Annu Rev Pharmacol Toxicol 2012;52:505-21
   PubMed Web of Science ®Google Scholar
• Zhang A, Sun H, Yang B, Predicting new molecular targets for rhein using network pharmacology. BMC Syst Biol 2012;6:20
   PubMed Web of Science ®Google Scholar
• Liu Q, Zhang Z, Fang L, Application of network pharmacology and high through-put technology on active compounds screening from traditional Chinese medicine. Zhongguo Zhong yao za zhi 2012;37(2):134-7
   PubMedGoogle Scholar
• Wu L, Gao X, Wang L, Prediction of multi-target of Aconiti Lateralis Radix Praeparata and its network pharmacology. Zhongguo Zhong yao za zhi 2011;36(21):2907-10
   PubMedGoogle Scholar
• Li X, Wu L, Fan X, Network pharmacology study on major active compounds of Fufang Danshen formula. Zhongguo Zhong yao za zhi 2011;36(21):2911-15
   PubMedGoogle Scholar
• Li S. Network target: a starting point for traditional Chinese medicine network pharmacology. Zhongguo Zhong yao za zhi 2011;36(15):2017-20
   PubMedGoogle Scholar
• Li S, Zhang B, Zhang N. Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC Syst Biol 2011;5(Suppl 1):S10
   PubMed Web of Science ®Google Scholar
• Li S, Zhang B, Jiang D, Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics 2010;11(Suppl 11):S6
   PubMed Web of Science ®Google Scholar
• Ganzera M. Recent advancements and applications in the analysis of traditional Chinese medicines. Planta Med 2009;75(7):776-83
   PubMed Web of Science ®Google Scholar
• Huang X, Kong L, Li X, Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines. J Chromatogr B Analyt Technol Biomed Life Sci 2004;812(1-2):71-84
   PubMed Web of Science ®Google Scholar
• Liang X, Jin Y, Wang Y, Qualitative and quantitative analysis in quality control of traditional Chinese medicines. J Chromatogr A 2009;1216(11):2033-44.
   PubMed Web of Science ®Google Scholar
• Yang M, Sun J, Lu Z, Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J Chromatogr A 2009;1216(11):2045-62
   PubMed Web of Science ®Google Scholar
• Zeng S, Wang L, Chen T, Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation. Anal Chim Acta 2012;733:38-47
   PubMed Web of Science ®Google Scholar
• Firn RD, Jones CG. The evolution of secondary metabolism - a unifying model. Mol Microbiol 2000;37(5):989-94
   PubMed Web of Science ®Google Scholar
• Gyllenhaal C, Kadushin MR, Southavong B, Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis. Pharm Biol 2012;50(1):30-41
   PubMed Web of Science ®Google Scholar
• Svetaz L, Zuljan F, Derita M, Value of the ethnomedical information for the discovery of plants with antifungal properties. A survey among seven Latin American countries. J Ethnopharmocol 2010;127(1):137-58
   PubMed Web of Science ®Google Scholar
• Ge J, Wang D, He R, Medicinal herb research: serum pharmacological method and plasma pharmacological method. Biol Pharm Bull 2010;33(9):1459-65
   PubMed Web of Science ®Google Scholar
• Eisenberg DM, Harris ESJ, Littlefield BA, Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation — Rationale, methods and preliminary results from a Sino-American collaboration. Fitoterapia 2011;82(1):17-33
   PubMed Web of Science ®Google Scholar
• Borris RP. Natural products research: perspectives from a major pharmaceutical company. J Ethnopharmocol 1996;51(1-3):29-38
   PubMed Web of Science ®Google Scholar
• Ma Y, Yuan L, Wu B, Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. J Exp Bot 2012;63(7):2809-23
   PubMed Web of Science ®Google Scholar
• Luo H, Sun C, Sun Y, Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. BMC Genomics 2011;12(Suppl 5):S5
   PubMed Web of Science ®Google Scholar
• Chen S, Xiang L, Guo X, An introduction to the medicinal plant genome project. Front Med 2011;5(2):178-84
   PubMedGoogle Scholar
• Corre C, Challis GL. New natural product biosynthetic chemistry discovered by genome mining. Nat Prod Rep 2009;26(8):977-86
   PubMed Web of Science ®Google Scholar
• Monks NR, Li B, Gunjan S, Natural Products Genomics: a novel approach for the discovery of anti-cancer therapeutics. J Pharmacol Toxicol Methods 2011;64(3):217-25
   PubMed Web of Science ®Google Scholar
• Zhou ML, Zhu XM, Shao JR, Production and metabolic engineering of bioactive substances in plant hairy root culture. Appl Microbiol Biotechnol 2011;90(4):1229-39
   PubMed Web of Science ®Google Scholar
• Zhao SJ, Li CY, Qian YC, Induction of hairy roots of Panax ginseng and studies on suitable culture condition of ginseng hairy roots. Sheng Wu Gong Cheng Xue Bao 2004;20(2):215-20
   PubMedGoogle Scholar
• Kong D-X, Li X-J, Tang G-Y, How many traditional chinese medicine components have been recognized by modern western medicine? A Chemoinformatic analysis and implications for finding multicomponent drugs. Chem Med Chem 2008;3(2):233-6
   Web of Science ®Google Scholar
• Lee B, Carles M, Sucher N. Traditional Chinese herbal medicines for the treatment of cardiovascular diseases. In: Ronald Watson, Victor R Preedy. Editors. Botanical Medicine in Clinical Practice, CABI, Cambridge, UK: 2008;1-16
   Google Scholar
• Camp D, Davis RA, Campitelli M, Drug-like properties: guiding principles for the design of natural product libraries. J Nat Prod 2012;75(1):72-81
   PubMed Web of Science ®Google Scholar
• Srinivas NR. Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives. Xenobiotica 2010;40(5):357-67
   PubMed Web of Science ®Google Scholar
• Dong Y, Morris-Natschke SL, Lee KH. Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents. Nat Prod Rep 2011;28(3):529-42
   PubMed Web of Science ®Google Scholar
• Ehrman TM, Barlow DJ, Hylands PJ. In silico search for multi-target anti-inflammatories in Chinese herbs and formulas. Bioorg Med Chem 2010;18(6):2204-18
   PubMed Web of Science ®Google Scholar
• Romeo JT, Saunders JA, Barbosa P, Phytochemical diversity and redundancy in ecological interactions. Plenum Press; New York: 1996
   Google Scholar
• Tononi G, Sporns O, Edelman GM. Measures of degeneracy and redundancy in biological networks. Proc Natl Acad Sci USA 1999;96(6):3257-62
   PubMed Web of Science ®Google Scholar
• Kong D-X, Li X-J, Zhang H-Y. Where is the hope for drug discovery? Let history tell the future. Drug Discov Today 2009;14(3-4):115-19
   PubMed Web of Science ®Google Scholar
• Wang L, Zhou GB, Liu P, Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci USA 2008;105(12):4826-31
   PubMed Web of Science ®Google Scholar
• Pieters L, Vlietinck AJ. Bioguided isolation of pharmacologically active plant components, still a valuable strategy for the finding of new lead compounds? J Ethnopharmocol 2005;100(1-2):57-60
   PubMed Web of Science ®Google Scholar
• Verpoorte R, Crommelin D, Danhof M, Commentary: “A systems view on the future of medicine: Inspiration from Chinese medicine?”. J Ethnopharmocol 2009;121(3):479-81
   PubMed Web of Science ®Google Scholar
• Tangalos EG, Zarowitz BJ. Combination drug therapy. J Am Med Dir Assoc 2005;6(6):406-9
   PubMedGoogle Scholar
• Cottarel G, Wierzbowski J. Combination drugs, an emerging option for antibacterial therapy. Trends Biotechnol 2007;25(12):547-55
   PubMed Web of Science ®Google Scholar
• Orloff DG. Fixed combination drugs for cardiovascular disease risk reduction: regulatory approach. Am J Cardiol 2005;96(9):28-33
   Web of Science ®Google Scholar
• Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007;5(4):345-51
   PubMedGoogle Scholar