microRNAs: a new class of breast cancer biomarkers

References

• Saini HK, Griffiths-Jones S, Enright AJ. Genomic analysis of human microRNA transcripts. Proc Natl Acad Sci USA 2007;104(45):17719-24
   PubMed Web of Science ®Google Scholar
• Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A. Identification of mammalian microRNA host genes and transcription units. Genome Res 2004;14(10A):1902-10
   PubMed Web of Science ®Google Scholar
• Lee Y, Kim M, Han J, et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 2004;23(20):4051-60
   PubMed Web of Science ®Google Scholar
• Borchert GM, Lanier W, Davidson BL. RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol 2006;13(12):1097-101
   PubMed Web of Science ®Google Scholar
• Denli AM, Tops BB, Plasterk RH, et al. Processing of primary microRNAs by the Microprocessor complex. Nature 2004;432(7014):231-5
   PubMed Web of Science ®Google Scholar
• Gregory RI, Yan KP, Amuthan G, et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 2004;432(7014):235-40
   PubMed Web of Science ®Google Scholar
• Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003;425(6956):415-19
   PubMed Web of Science ®Google Scholar
• Ruby JG, Jan CH, Bartel DP. Intronic microRNA precursors that bypass Drosha processing. Nature 2007;448(7149):83-6
   PubMed Web of Science ®Google Scholar
• Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003;17(24):3011-16
   PubMed Web of Science ®Google Scholar
• Schwarz DS, Hutvagner G, Du T, et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003;115(2):199-208
   PubMed Web of Science ®Google Scholar
• Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003;115(2):209-16
   PubMed Web of Science ®Google Scholar
• Hu HY, Yan Z, Xu Y, et al. Sequence features associated with microRNA strand selection in humans and flies. BMC Genomics 2009;10:413
   PubMed Web of Science ®Google Scholar
• Petrarca CR, Brunetto AT, Duval V, et al. Survivin As a Predictive Biomarker of Complete Pathologic Response to Neoadjuvant Chemotherapy in Patients With Stage II and Stage III Breast Cancer. Clin Breast Cancer 2011;11(2):129-34
   PubMed Web of Science ®Google Scholar
• Stendahl M, Nilsson S, Wigerup C, et al. p27Kip1 is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients. Int J Cancer 2010;127(12):2851-8
   PubMed Web of Science ®Google Scholar
• Ramirez NE, Zhang Z, Madamanchi A, et al. The alphabeta integrin is a metastasis suppressor in mouse models and human cancer. J Clin Invest 2011;121(1):226-37
   PubMed Web of Science ®Google Scholar
• Li XR, Liu M, Zhang YJ, et al. CK5/6, EGFR, Ki-67, cyclin D1, and nm23-H1 protein expressions as predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer patients. Med Oncol 2011;28(Suppl 1):S129-34
   PubMedGoogle Scholar
• Horiguchi K, Toi M, Horiguchi S, et al. Predictive value of CD24 and CD44 for neoadjuvant chemotherapy response and prognosis in primary breast cancer patients. J Med Dent Sci 2010;57(2):165-75
   PubMedGoogle Scholar
• Lee E, Nichols P, Groshen S, et al. GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy. Int J Cancer 2011;128(3):726-31
   PubMed Web of Science ®Google Scholar
• Giusiano S, Secq V, Carcopino X, et al. Immunohistochemical profiling of node negative breast carcinomas allows prediction of metastatic risk. Int J Oncol 2010;36(4):889-98
   PubMed Web of Science ®Google Scholar
• Le Quesne J, Caldas C. Micro-RNAs and breast cancer. Mol Oncol 2010;4(3):230-41
   PubMed Web of Science ®Google Scholar
• Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009;19(1):92-105
   PubMed Web of Science ®Google Scholar
• Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5’ UTR as in the 3’ UTR. Proc Natl Acad Sci USA 2007;104(23):9667-72
   PubMed Web of Science ®Google Scholar
• Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA 2008;105(39):14879-84
   PubMed Web of Science ®Google Scholar
• Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev 2004;18(5):504-11
   PubMed Web of Science ®Google Scholar
• Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005;120(1):15-20
   PubMed Web of Science ®Google Scholar
• Nielsen CB, Shomron N, Sandberg R, et al. Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA 2007;13(11):1894-910
   PubMed Web of Science ®Google Scholar
• Brennecke J, Stark A, Russell RB, Cohen SM. Principles of microRNA-target recognition. PLoS Biol 2005;3(3):e85
   PubMed Web of Science ®Google Scholar
• Grimson A, Farh KK, Johnston WK, et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 2007;27(1):91-105
   PubMed Web of Science ®Google Scholar
• Chi SW, Hannon GJ, Darnell RB. An alternative mode of microRNA target recognition. Nat Struct Mol Biol 2012;19(3):321-7
   PubMed Web of Science ®Google Scholar
• Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010;466(7308):835-40
   PubMed Web of Science ®Google Scholar
• Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004;304(5670):594-6
   PubMed Web of Science ®Google Scholar
• Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011;12(2):99-110
   PubMed Web of Science ®Google Scholar
• Salmena L, Poliseno L, Tay Y, et al. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 2011;146(3):353-8
   PubMed Web of Science ®Google Scholar
• Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005;65(16):7065-70
   PubMed Web of Science ®Google Scholar
• Blenkiron C, Goldstein LD, Thorne NP, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol 2007;8(10):R214
   PubMed Web of Science ®Google Scholar
• Sempere LF, Christensen M, Silahtaroglu A, et al. Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res 2007;67(24):11612-20
   PubMed Web of Science ®Google Scholar
• Mattie MD, Benz CC, Bowers J, et al. Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol cancer 2006;5:24
   PubMed Web of Science ®Google Scholar
• Ali S, Saleh H, Sethi S, et al. MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer. Br J Cancer 2012;107(8):1354-60
   PubMed Web of Science ®Google Scholar
• Mazeh H, Mizrahi I, Halle D, et al. Development of a microRNA-based molecular assay for the detection of papillary thyroid carcinoma in aspiration biopsy samples. Thyroid 2011;21(2):111-18
   PubMed Web of Science ®Google Scholar
• Brase JC, Wuttig D, Kuner R, Sultmann H. Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer 2010;9:306
   PubMed Web of Science ®Google Scholar
• Zhu W, Qin W, Atasoy U, Sauter ER. Circulating microRNAs in breast cancer and healthy subjects. BMC Res Notes 2009;2:89
   PubMedGoogle Scholar
• Wang F, Zheng Z, Guo J, Ding X. Correlation and quantitation of microRNA aberrant expression in tissues and sera from patients with breast tumor. Gynecol Oncol 2010;119(3):586-93
   PubMed Web of Science ®Google Scholar
• Sun Y, Wang M, Lin G, et al. Serum MicroRNA-155 as a Potential Biomarker to Track Disease in Breast Cancer. PLoS One 2012;7(10):e47003
   PubMed Web of Science ®Google Scholar
• Roth C, Rack B, Muller V, et al. Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer. Breast Cancer Res 2010;12(6):R90
   PubMed Web of Science ®Google Scholar
• Liu J, Mao Q, Liu Y, et al. Analysis of miR-205 and miR-155 expression in the blood of breast cancer patients. Chin J Cancer Res 2013;25(1):46-54
   PubMed Web of Science ®Google Scholar
• Mar-Aguilar F, Mendoza-Ramirez JA, Malagon-Santiago I, et al. Serum circulating microRNA profiling for identification of potential breast cancer biomarkers. Dis Markers 2013;34(3):163-9
   PubMed Web of Science ®Google Scholar
• Asaga S, Kuo C, Nguyen T, et al. Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer. Clin Chem 2011;57(1):84-91
   PubMed Web of Science ®Google Scholar
• Schwarzenbach H, Milde-Langosch K, Steinbach B, et al. Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients. Breast Cancer Res Treat 2012;134(3):933-41
   PubMed Web of Science ®Google Scholar
• Si H, Sun X, Chen Y, et al. Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer. J Cancer Res Clin Oncol 2013;139(2):223-9
   PubMed Web of Science ®Google Scholar
• Kumar S, Keerthana R, Pazhanimuthu A, Perumal P. Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients. Indian J Biochem Biophys 2013;50(3):210-14
   PubMed Web of Science ®Google Scholar
• Ng EK, Li R, Shin VY, et al. Circulating microRNAs as specific biomarkers for breast cancer detection. PLoS One 2013;8(1):e53141
   PubMed Web of Science ®Google Scholar
• Chen W, Cai F, Zhang B, et al. The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers. Tumour Biol 2013;34(1):455-62
   PubMedGoogle Scholar
• Madhavan D, Zucknick M, Wallwiener M, et al. Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer. Clin Cancer Res 2012;18(21):5972-82
   PubMed Web of Science ®Google Scholar
• Cuk K, Zucknick M, Heil J, et al. Circulating microRNAs in plasma as early detection markers for breast cancer. Int J Cancer 2013;132(7):1602-12
   PubMed Web of Science ®Google Scholar
• Cuk K, Zucknick M, Madhavan D, et al. Plasma MicroRNA Panel for Minimally Invasive Detection of Breast Cancer. PLoS One 2013;8(10):e76729
   PubMed Web of Science ®Google Scholar
• Heneghan HM, Miller N, Lowery AJ, et al. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann Surg 2010;251(3):499-505
   PubMed Web of Science ®Google Scholar
• Heneghan HM, Miller N, Kelly R, et al. Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease. Oncologist 2010;15(7):673-82
   PubMed Web of Science ®Google Scholar
• Zhao H, Shen J, Medico L, et al. A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer. PLoS One 2010;5(10):e13735
   PubMed Web of Science ®Google Scholar
• Godfrey AC, Xu Z, Weinberg CR, et al. Serum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohort. Breast Cancer Res 2013;15(3):R42
   PubMed Web of Science ®Google Scholar
• Chan M, Liaw CS, Ji SM, et al. Identification of circulating microRNA signatures for breast cancer detection. Clin Cancer Res 2013;19(16):4477-87
   PubMed Web of Science ®Google Scholar
• Leidner RS, Li L, Thompson CL. Dampening enthusiasm for circulating microRNA in breast cancer. PLoS One 2013;8(3):e57841
   PubMed Web of Science ®Google Scholar
• Mulrane L, Madden SF, Brennan DJ, et al. miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in Vitro. Clin Cancer Res 2012;18(24):6702-13
   PubMed Web of Science ®Google Scholar
• Yan LX, Huang XF, Shao Q, et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008;14(11):2348-60
   PubMed Web of Science ®Google Scholar
• Qian B, Katsaros D, Lu L, et al. High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1. Breast Cancer Res Treat 2009;117(1):131-40
   PubMed Web of Science ®Google Scholar
• Walter BA, Gomez-Macias G, Valera VA, et al.J. miR-21 expression in pregnancy-associated breast cancer: a possible marker of poor prognosis. J Cancer 2011;2:67-75
   PubMed Web of Science ®Google Scholar
• Lee JA, Lee HY, Lee ES, et al. Prognostic Implications of MicroRNA-21 Overexpression in Invasive Ductal Carcinomas of the Breast. J Breast Cancer 2011;14(4):269-75
   PubMed Web of Science ®Google Scholar
• Camps C, Buffa FM, Colella S, et al. hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res 2008;14(5):1340-8
   PubMed Web of Science ®Google Scholar
• Toyama T, Kondo N, Endo Y, et al. High expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patients. Jpn J Clin Oncol 2012;42(4):256-63
   PubMed Web of Science ®Google Scholar
• Foekens JA, Sieuwerts AM, Smid M, et al. Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc Natl Acad Sci USA 2008;105(35):13021-6
   PubMed Web of Science ®Google Scholar
• Buffa FM, Camps C, Winchester L, et al. microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res 2011;71(17):5635-45
   PubMed Web of Science ®Google Scholar
• Chen J, Wang BC, Tang JH. Clinical significance of microRNA-155 expression in human breast cancer. J Surg Oncol 2012;106(3):260-6
   PubMed Web of Science ®Google Scholar
• Kong W, He L, Richards EJ, et al. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene 2014;33(6):679-89
   PubMed Web of Science ®Google Scholar
• Gao LB, Bai P, Pan XM, et al. The association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 2011;125(2):571-4
   PubMed Web of Science ®Google Scholar
• Shen J, Ambrosone CB, DiCioccio RA, et al. A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 2008;29(10):1963-6
   PubMed Web of Science ®Google Scholar
• Saetrom P, Biesinger J, Li SM, et al. A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. Cancer Res 2009;69(18):7459-65
   PubMed Web of Science ®Google Scholar
• Brendle A, Lei H, Brandt A, et al. Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker. Carcinogenesis 2008;29(7):1394-9
   PubMed Web of Science ®Google Scholar
• de Rinaldis E, Gazinska P, Mera A, et al. Integrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they control. BMC Genomics 2013;14(1):643
   PubMedGoogle Scholar
• Paik S, Shak S, Tang G, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004;351(27):2817-26
   PubMed Web of Science ®Google Scholar
• Paik S, Tang G, Shak S, et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol 2006;24(23):3726-34
   PubMed Web of Science ®Google Scholar
• van’t Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002;415(6871):530-6
   PubMed Web of Science ®Google Scholar
• van de Vijver MJ, He YD, van’t Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002;347(25):1999-2009
   PubMed Web of Science ®Google Scholar
• Volinia S, Croce CM. Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer. Proc Natl Acad Sci USA 2013;110(18):7413-17
   PubMed Web of Science ®Google Scholar
• Tavazoie SF, Alarcon C, Oskarsson T, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008;451(7175):147-52
   PubMed Web of Science ®Google Scholar
• Hoppe R, Achinger-Kawecka J, Winter S, et al. Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment. Eur J Cancer 2013;49(17):3598-608
   PubMed Web of Science ®Google Scholar
• Jansen MP, Reijm EA, Sieuwerts AM, et al. High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer. Breast Cancer Res Treat 2012;133(3):937-47
   PubMed Web of Science ®Google Scholar
• Rodriguez-Gonzalez FG, Sieuwerts AM, Smid M, et al. MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer. Breast Cancer Res Treat 2011;127(1):43-51
   PubMed Web of Science ®Google Scholar
• Shi W, Gerster K, Alajez NM, et al. MicroRNA-301 mediates proliferation and invasion in human breast cancer. Cancer Res 2011;71(8):2926-37
   PubMed Web of Science ®Google Scholar
• Zhu Y, Yu F, Jiao Y, et al. Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 2011;17(22):7105-15
   PubMed Web of Science ®Google Scholar
• Zhao R, Wu J, Jia W, et al. Plasma miR-221 as a Predictive Biomarker for Chemoresistance in Breast Cancer Patients who Previously Received Neoadjuvant Chemotherapy. Onkologie 2011;34(12):675-80
   PubMedGoogle Scholar
• Wang H, Tan G, Dong L, et al. Circulating MiR-125b as a marker predicting chemoresistance in breast cancer. PLoS One 2012;7(4):e34210
   PubMed Web of Science ®Google Scholar
• Madden SF, Carpenter SB, Jeffery IB, et al. Detecting microRNA activity from gene expression data. BMC Bioinformatics 2010;11:257
   PubMed Web of Science ®Google Scholar
• Cheng C, Li LM. Inferring microRNA activities by combining gene expression with microRNA target prediction. PLoS One 2008;3(4):e1989
   PubMed Web of Science ®Google Scholar
• Creighton CJ, Nagaraja AK, Hanash SM, et al. A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA 2008;14(11):2290-6
   PubMed Web of Science ®Google Scholar
• Madden SF, Clarke C, Gaule P, et al. BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome. Breast Cancer Res 2013;15(4):R52
   PubMed Web of Science ®Google Scholar
• Kozomara A, Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucl Acids Res 2013;42(Database issue):D68-73
   PubMedGoogle Scholar
• Valastyan S, Reinhardt F, Benaich N, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009;137(6):1032-46
   PubMed Web of Science ®Google Scholar
• Pritchard CC, Kroh E, Wood B, et al. Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev Res (Phila) 2012;5(3):492-7
   PubMed Web of Science ®Google Scholar
• Kirschner MB, Kao SC, Edelman JJ, et al. Haemolysis during sample preparation alters microRNA content of plasma. PLoS One 2011;6(9):e24145
   PubMed Web of Science ®Google Scholar
• McDonald JS, Milosevic D, Reddi HV, et al. Analysis of circulating microRNA: preanalytical and analytical challenges. Clin Chem 2011;57(6):833-40
   PubMed Web of Science ®Google Scholar
• Xie Y, Todd NW, Liu Z, et al. Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer. Lung Cancer 2010;67(2):170-6
   PubMed Web of Science ®Google Scholar
• Tanaka M, Oikawa K, Takanashi M, et al. Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients. PLoS One 2009;4(5):e5532
   PubMed Web of Science ®Google Scholar
• Asaga S, Hoon DS. Direct serum assay for microRNA in cancer patients. Methods Mol Biol 2013;1024:147-55
   PubMedGoogle Scholar
• Li J, Smyth P, Flavin R, et al. Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol 2007;7:36
   PubMed Web of Science ®Google Scholar
• Xi Y, Nakajima G, Gavin E, et al. Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA 2007;13(10):1668-74
   PubMed Web of Science ®Google Scholar
• Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993;75(5):843-54
   PubMed Web of Science ®Google Scholar
• Janssen HL, Reesink HW, Lawitz EJ, et al. Treatment of HCV infection by targeting microRNA. N Engl J Med 2013;368(18):1685-94
   PubMed Web of Science ®Google Scholar
• Zeng RC, Zhang W, Yan XQ, et al. Down-regulation of miRNA-30a in human plasma is a novel marker for breast cancer. Med Oncol 2013;30(1):477
   PubMed Web of Science ®Google Scholar
• Guo LJ, Zhang QY. Decreased serum miR-181a is a potential new tool for breast cancer screening. Int J Mol Med 2012;30(3):680-6
   PubMed Web of Science ®Google Scholar
• Wang PY, Gong HT, Li BF, et al. Higher expression of circulating miR-182 as a novel biomarker for breast cancer. Oncol Lett 2013;6(6):1681-6
   PubMed Web of Science ®Google Scholar
• Schrauder MG, Strick R, Schulz-Wendtland R, et al. Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection. PLoS One 2012;7(1):e29770
   PubMed Web of Science ®Google Scholar
• Ma L, Li GZ, Wu ZS, Meng G. Prognostic significance of let-7b expression in breast cancer and correlation to its target gene of BSG expression. Med Oncol 2014;31(1):773
   PubMed Web of Science ®Google Scholar
• Zhou X, Marian C, Makambi KH, et al. MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status. PLoS One 2012;7(6):e39011
   PubMed Web of Science ®Google Scholar
• Tang W, Zhu J, Su S, et al. MiR-27 as a prognostic marker for breast cancer progression and patient survival. PLoS One 2012;7(12):e51702
   PubMed Web of Science ®Google Scholar
• Cheng CW, Wang HW, Chang CW, et al. MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat 2012;134(3):1081-93
   PubMed Web of Science ®Google Scholar
• Peurala H, Greco D, Heikkinen T, et al. MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer. PLoS One 2011;6(11):e26122
   PubMed Web of Science ®Google Scholar
• Svoboda M, Sana J, Redova M, et al. MiR-34b is associated with clinical outcome in triple-negative breast cancer patients. Diagn Pathol 2012;7:31
   PubMed Web of Science ®Google Scholar
• Nilsson S, Moller C, Jirstrom K, et al. Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. PLoS One 2012;7(4):e36051
   PubMed Web of Science ®Google Scholar
• Jonsdottir K, Janssen SR, Da Rosa FC, et al. Validation of expression patterns for nine miRNAs in 204 lymph-node negative breast cancers. PLoS One 2012;7(11):e48692
   PubMed Web of Science ®Google Scholar
• Bisso A, Faleschini M, Zampa F, et al. Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. Cell Cycle 2013;12(11):1679-87
   PubMed Web of Science ®Google Scholar
• Hanna JA, Wimberly H, Kumar S, et al. Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization. Biotechniques 2012;52(4):235-45
   PubMed Web of Science ®Google Scholar
• Lerebours F, Cizeron-Clairac G, Susini A, et al. miRNA expression profiling of inflammatory breast cancer identifies a 5-miRNA signature predictive of breast tumor aggressiveness. Int J Cancer 2013;133(7):1614-23
   PubMed Web of Science ®Google Scholar
• Wu ZS, Wu Q, Wang CQ, et al. miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met. Cancer 2011;117(13):2842-52
   PubMed Web of Science ®Google Scholar
• Wang S, Li H, Wang J, Wang D. Expression of microRNA-497 and its prognostic significance in human breast cancer. Diagn Pathol 2013;8(1):172
   PubMedGoogle Scholar