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Expert Review of Molecular Diagnostics Volume 16, 2016 - Issue 2
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Reviews

A liquid biopsy for head and neck cancers

Henri SchmidtThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Australia
,
Arutha KulasingheThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Australia
,
Chris PerryDepartment of Otolaryngology, Princess Alexandra Hospital, Woolloongabba, Australia
,
Colleen NelsonAustralian Prostate Cancer Research Centre-Queensland, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia
&
Chamindie PunyadeeraThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, AustraliaCorrespondence[email protected]
Pages 165-172 | Received 22 Sep 2015, Accepted 01 Dec 2015, Published online: 18 Jan 2016

References

  • Papers of special note have been highlighted as: • of interest •• of considerable interest
  • Riaz N, Morris LG, Lee W, et al. Unraveling the molecular genetics of head and neck cancer through genome-wide approaches. Genes Dis. 2014;1(1):75–86.
  • Rothenberg SM, Ellisen LW. The molecular pathogenesis of head and neck squamous cell carcinoma. J Clin Invest. 2012;122(6):1951–1957.
  • Jatana KR, Balasubramanian P, Lang JC, et al. Significance of circulating tumor cells in patients with squamous cell carcinoma of the head and neck. JAMA Otolaryngol Head Neck Surg. 2010;136(12):1274–1279.
  • Wang Z, Cui K, Xue Y, et al. Prognostic value of circulating tumour cells in patients with squamous cell carcinoma of the head and neck: a systematic review and meta-analysis. Med Oncol. 2015;32(5):164.
  • Denaro N, Russi EG, Adamo V, et al. State-of-the-art and emerging treatment options in the management of head and neck cancer: news from 2013. Oncology. 2014;86(4):212–229.
  • He S, Li P, He S, et al. Detection of circulating tumour cells with the CellSearch system in patients with advanced-stage head and neck cancer: preliminary results. J Laryngol Otol. 2013;127(8):788–793.
  • Vermorken JB, Specenier P. Optimal treatment for recurrent/metastatic head and neck cancer. Ann Oncol. 2010;21(Suppl 7):vii252–261.
  • Levy A, De Felice F, Bellefqih S, et al. Toxicity of concomitant cetuximab and radiotherapy with or without initial taxane-based induction chemotherapy in locally advanced head and neck cancer. Head Neck. 2015. doi:10.1002/hed.24125. [Epub ahead of print]
  • Visacri MB, Ferrari GB, Dias P, et al. Quality of life of patients with squamous cell carcinoma of the head and neck receiving high-dose cisplatin chemotherapy and radiotherapy. South Med J. 2015;108(6):343–349.
  • Bar-Ad V, Palmer J, Yang H, et al. Current management of locally advanced head and neck cancer: the combination of chemotherapy with locoregional treatments. Semin Oncol. 2014;41(6):798–806.
  • Grisanti S, Almici C, Consoli F, et al. Circulating tumour cells in patients with recurrent or metastatic head and neck carcinoma: prognostic and predicitve significance. PLOS One. 2014;9(8):e103918.
  • Zhi X, Lamperska K, Golusinski P, et al. Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence. Oncotarget. 2015;6(1):547–555.
  • Kulasinghe A, Perry C, Jovanovich L, et al. Circulating tumor cells in metastatic head and neck cancers. Int J Cancer. 2015;136(11):2515–2523.

• Comprehensive review of circulating tumour cells in Head and neck cancer.

  • Chai CR, Lambie D, Verma M, et al. Current trends in the etiology and diagnosis of HPV-related head and neck cancers. Cancer Med. 2015;4(4):596–607.
  • Bruni L, Barrionuevo-Rosas L, Albero G, et al. Human Papillomavirus and Related Diseases in the World. Summary Report 2015-04-08. Barcelona: ICO Information Centre on HPV and Cancer (HPV Information Centre).
  • Sanderson RJ, Ironside JAD. Squamous cell carcinomas of the head and neck. BMJ. 2002;325(7368);822–827.
  • Ferlito A, Shaha AR, Silver CE, et al. Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec. 2001;63(4):202–207.
  • Kotwall C, Sako K, Razack MS, et al. Metastatic patterns in squamous cell carcinoma of the head and neck. Am J Surg. 1987;154:439–442.
  • Rose BS, Jeong JH, Nath SK, et al. Population-based study of competing mortality in head and neck cancer. J Clin Oncol. 2011;29(26):3503–3509.
  • Head and Neck Cancer-Diagnosis [Internet]. American Society of Clinical Oncology (ASCO) - Cancer.net. 2015 [cited 2015 Oct 10]. Available from: www.cancer.net/cancer-types/head-and-neck-cancer/diagnosis.
  • Diagnosing head and neck cancers [Internet]. Cancer Council Victoria. 2015 [cited 2015 Oct 10]. Available from: http://www.cancervic.org.au/about-cancer/cancer_types/head-neck-cancers/diagnosing-head-neck.html.
  • Alix-Panabieres C, Pantel K. Real-time liquid biopsy: circulating tumour cells versus circulating tumour DNA. Ann Transl Med. 2013;1(2):18.
  • Hakima L, Adler E, Prystowsky M, et al. Hybrid capture 2 human papillomavirus testing of fine needle aspiration cytology of head and neck squamous cell carcinomas. Diagn Cytopathol. 2015;43(9):683–687.
  • Krebs MG, Metcalf RL, Carter L, et al. Molecular analysis of circulating tumour cells - biology and biomarkers. Nat Rev Clin Oncol. 2014;11(3):129–144.
  • Economopoulou P, Bourhis J, Psyrri A. Research progress in head and neck squamous cell carcinoma: best abstracts of ICHNO2015. Am Soc Clin Oncol book. 2015:e323–328. doi:10.14694/EdBook_AM.2015.35.e323.
  • Heitzer E, Ulz P, Geigl BJ. Circulating tumour cells as a liquid biopsy for cancer. Clin Chem. 2015;61(1):112–123.
  • Lebofsky R, Decraene C, Bernard V, et al. Circulating tumour DNA as a non-invasive substitute to metastasis biopsyfor tumour genotyping and personalised medicine in a prospective trial across all tumour types. Mol Oncol. 2015;9(4):783–790.
  • Diehl F, Schmidt K, Choti MA, et al. Circulating mutant DNA to assess tumour dynamics. Nat Med. 2008;14(9):985–990.
  • Gold B, Cankovic M, Furtado LV, et al. Do circulating tumour cells, exosomes and circulating nucleic acids have clinical ultility? A report for the association of molecular pathology. J Mol Diagn. 2015;17(3):209–224.
  • Zapparoli GV, Jorissen RN, Hewitt CA, et al. Quantitative threefold allele-specific PCR (QuantTAS-PCR) for highly sensitive JAK2 V617 mutant allele detection. BMC Cancer. 2013;13:206.
  • Olsson E, Winter C, George A, et al. Serial monitoring of circulating tumour DNA in patients with primary breast cancer for detection of occult metastatic disease. EMBO Mol Med. 2015;7(8):1034–1047.
  • Guney K, Yoldas B, Ozbilim G, et al. Detection of micrometastatic tumour cells in head and neck squamous cell carcinoma: a possible predictor of recurrence. Saudi Med J. 2007;28(2):216–220.
  • Li J, Gregory SG, Garcia-Blanco MA, et al. Using circulating tumour cells to inform on prostate cancer biology and clinical utility. Crit Rev Clin Lab Sci. 2015;52(4):191–210.
  • Dieguez L, Winter MA, Pocock KJ, et al. Efficient microfuidic negative enrichment of circulating tumour cells in blood using roughened PDMS. Royal. 2015;140(10):3565–3572.
  • Khoo BL, Lee SC, Kumar P, et al. Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy. Oncotarget. 2015;6(17):15578–15593.
  • Khoo BL, Warkiani ME, Tan DS-W, et al. Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumour cells. PLOS One. 2014;9:e99409.
  • Warkiani ME, Guan G, Luan KB, et al. Slanted spiral microfluidics for the ultra-fast label-free isolation of circulating tumour cells. Lab Chip. 2014;14(1):128–137.
  • Vela I, Chen Y. Prostate cancer organoids: a potential new tool for testing drug sensitivity. Exp Rev Anticancer Ther. 2015;15(3):261–263.

• Key manuscript of culturing circulating tumour cells.

  • Gao D, Vela I, Sboner A, et al. Organoid cultures derived from patients with advanced prostate cancer. Cell. 2014;159(1):176–187.
  • Hodgkinson CL, Morrow CJ, Li Y, et al. Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer. Nat Med. 2014;20(8):159(1):897–903.
  • Dawson S-J, Tsui DWY, Murtaza M, et al. Analysis of circulating tumour DNA to monitor metastatic breast cancer. N Engl J Med. 2013;368:1199–1209.
  • Haber DA, Velculescu VE. Blood-based anaylses of cancer: circulating tumour cells and circulating tumour DNA. Cancer Discov. 2014;4(6):650–661.
  • Bettegowda C, Sausen M, Leary RJ, et al. Detection of circulating tumour DNA in early- and late-stage human malignancies. Sci Transl Med. 2014;6(224):224ra24. doi:10.1126/scitranslmed.3007094

•• Landmark study in the use of ctDNA across multiple cancer types.

  • Diehl F, Li M, Dressman D, et al. Detection and quantification of mutations in the plasma of patients with colorectal tumours. PNAS. 2005;102(45):25(12):16368–16373.
  • Ignatiadis M, Dawson SJ. Circulating tumour cells and circulating tumour DNA for precision medicine. Dream or reality? Ann Oncol. 2014;25(12):2304–2313.
  • Comprehensive genomic characterisation of head and neck squamous cell carcinoma. Nature. 2015;17:576–82.

•• Landmark study of the genomic landscape in head and neck cancer.

  • Heitzer E, Ulz P, Geigl JB. Circulating tumour DNA as a liquid biopsy for cancer. Clin Chem. 2015;61(1):112–123.
  • Wang Y, Simeon S, Mulvey CL, et al. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Cancer. 2015;7(293):1–7.

•• Key manuscript detecting somatic mutations using biofluids in head and neck cancer.

  • Langer CJ. Exploring biomarkers in head and neck cancer. Cancer. 2012;118(16):3282–3292.
  • Campitelli M, Jeannot E, Peter M, et al. Human papillomavirus mutational insertion: specific markers of circulating tumour DNA in cervical cancer patients. PLOS One. 2012;7:e43393.
  • Zhang B, Xu CW, Shao Y, et al. Comparison of the droplet digital PCR and conventional quantitative PCR for measuring EGFR mutation. Exp Ther Med. 2014;9(4):1383–1388.
  • Pekin D, Skhiri Y, Baret JC, et al. Quantitative and sensitive detection of rare mutations using droplet-based microfluidics. Lab Chip. 2011;11(13):2156–2166.
  • Xu Q, Zhu Y, Bai Y, et al. Detection of epidermal growth factor receptor mutation in lung cancer by droplet digital polymerase chain reaction. Onco Targets Ther. 2015;8:1533–1541.
  • Belic J, Koch M, Ulz P, et al. Rapid identification of plasma DNA samples with increased ctDNA levels by modified FAST-SeqS approach. Clin Chem. 2015;61(6):838–849.
  • Principe S, Hui AB, Bruce J, et al. Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery. Proteomics. 2013;13(10–11):1608–1623.
  • Zhang X, Kulasinghe A, Karim RS, et al. Advances in Salivary Diagnostics. Berlin: Springer Science; 2015. Chapter 7, Saliva Diagnostics of Oral Diseases; p. 131–156.
  • Kulasinghe A, Lim YK, Punyadeera C, et al. Head and Neck Cancer: Epidemiology, Management and Treatment Outcomes. Hauppauge (NY): Nova Science; 2015. Chapter 4, Current trends and management in head and neck cancers; p. 41–73.
  • Salazar C, Nagadia R, Pandit P, et al. DNA methylation at the novel CpG sites in the promoter of MED15/PCQAP gene as a biomarker for head and neck cancers. Biomark Insights. 2014;9:53–60.
  • Salazar C, Nagadia R, Pandit P, et al. A novel saliva-based microRNA biomarker panel to detect head and neck cancers. Cell Oncol. 2014;37(5):331–338.

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