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Immune therapy in autoimmune encephalitis: a systematic review

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References

  • Papers of special note have been highlighted as:
  • •• of considerable interest
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•• The first description of anti-N-methyl-d-aspartate receptor antibodies.

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•• Results of this study show a statistically significant association between good outcome and use of immune therapy.

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•• Results of this study show a statistically significant association between good outcome and early commencement of rituximab.

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•• Results of this study show a statistically significant association between good outcome and use of immune therapy, especially when started early in the course of the disease.

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•• The largest case series of patients with anti-N-methyl-d-aspartate receptor encephalitis, providing important data on treatment. Results of this study show that good outcome was significantly associated with early commencement of immune therapy and use second-line immune therapy. Relapse rate was significantly decreased in patients treated with immune therapy compared to those not treated and in patients who received second-line therapies.

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•• Results of this study show a statistically significant association between good outcome and early commencement of immune therapy.

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•• Results of this prospective study show a statistically significant association between good outcome (seizure reduction and good cognitive outcome) and use of immune therapy, and between time to recover and time to commencement of immune therapy.

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•• Results of this study show a statistically significant association between good outcome and use of immune therapy.

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