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Diagnosis and therapy of acute disseminated encephalomyelitis and its variants

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References

•• The largest prospective study on post-infectious encephalomyelitis to date, it reports a subgroup of 64 patients with combined central and peripheral demyelination and poorer outcome.

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• A large prospective study on any-age ADEM patients that reports in detail the clinical and paraclinical features of the cohort.

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•• A large prospective series that is considered the pivotal study on pediatric ADEM patients.

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•• An original report of 13 children with CCPD and poor clinical outcome.

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• A recent nationwide survey that sets the CCPD phenomenon into a population context.

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• A detailed description of 5 pediatric cases of CCPD.

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• An interesting study on the different OCB patterns observed in inflammatory demyelinating disorders and their possible relation to disease pathogenesis.

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• The first prospective study on postinfectious encephalomyelitis to evidence the existence of variants characterized by site-restricted damage or additional PNS involvement.

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• This study provides useful elements to the in-depth understanding of ADEM pathogenesis.

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• A comprehensive description of the distinctive neuropathological features of ADEM.

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• This study provides useful elements to the in-depth understanding of ADEM pathogenesis.

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•• The latest Consensus definitions proposed for ADEM in the pediatric cohort.

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