An update on the comorbidity of ADHD and ASD: a focus on clinical management

References

• APA. Diagnostic and statistical manual of mental disorders. 5th ed. Washington (DC): American Psychiatric Publishing; 2013.
   Google Scholar
• APA. DSM-IV-TR. Washington (DC): American Psychiatric Association; 2000.
   Google Scholar
• Sprenger L, Bühler E, Poustka L, et al. Impact of ADHD symptoms on autism spectrum disorder symptom severity. Res Dev Disabil. 2013;34(10):3545–3552.
   PubMed Web of Science ®Google Scholar
• Russell G, Rodgers LR, Ford T. The strengths and difficulties questionnaire as a predictor of parent-reported diagnosis of autism spectrum disorder and attention deficit hyperactivity disorder. PLoS One. 2013;8(12):e80247.
   PubMed Web of Science ®Google Scholar
• Frazier TW, Youngstrom EA, Embacher R, et al. Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis. Autism. 2014;18(5):571–582.
   PubMed Web of Science ®Google Scholar
• Ronald A, Larsson H, Anckarsäter H, et al. Symptoms of autism and ADHD: a Swedish twin study examining their overlap. J Abnorm Psychol. 2014;123(2):440–451.
   PubMed Web of Science ®Google Scholar
• Kotte A, Joshi G, Fried R, et al. Autistic traits in children with and without ADHD. Pediatrics. 2013;132(3):e612–622.
   Google Scholar
• Cooper M, Martin J, Langley K, et al.. Autistic traits in children with ADHD index clinical and cognitive problems. Eur Child Adolesc Psychiatry. 2014;23(1):23–34.
   PubMed Web of Science ®Google Scholar
• Jensen CM, Steinhausen H-C. Comorbid mental disorders in children and adolescents with attention-deficit/hyperactivity disorder in a large nationwide study. Atten Defic Hyperact Disord. 2015;7(1):27–38.
   PubMedGoogle Scholar
• Joshi G, Faraone SV, Wozniak J, et al. Symptom profile of ADHD in youth with high-functioning autism spectrum disorder: a comparative study in psychiatrically referred populations. J Atten Disord. 2014 Aug 1. doi:10.1177/1087054714543368. [Epub ahead of print].
   PubMedGoogle Scholar
• Joshi G, Faraone SV, Wozniak J, et al. Examining the clinical correlates of autism spectrum disorder in youth by ascertainment source. J Autism Dev Disord. 2014;44(9):2117–2126.
   PubMed Web of Science ®Google Scholar
• Salazar F, Baird G, Chandler S, et al. Co-occurring psychiatric disorders in preschool and elementary school-aged children with autism spectrum disorder. J Autism Dev Disord. 2015;45(8):2283–2294.
   PubMed Web of Science ®Google Scholar
• Kaat AJ, Gadow KD, Lecavalier L. Psychiatric symptom impairment in children with autism spectrum disorders. J Abnorm Child Psychol. 2013;41(6):959–969.
   PubMed Web of Science ®Google Scholar
• van der Meer JM, Oerlemans AM, van Steijn DJ, et al. Are autism spectrum disorder and attention-deficit/hyperactivity disorder different manifestations of one overarching disorder? Cognitive and symptom evidence from a clinical and population-based sample. J Am Acad Child Adolesc Psychiatry. 2012;51(11):1160–1172.e3.
   PubMed Web of Science ®Google Scholar
• Musser ED, Hawkey E, Kachan-Liu SS, et al. Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders. J Child Psychol Psychiatry. 2014;55(7):819–827.
   PubMed Web of Science ®Google Scholar
• Pettersson E, Anckarsäter H, Gillberg C, et al. Different neurodevelopmental symptoms have a common genetic etiology. J Child Psychol Psychiatry. 2013;54(12):1356–1365.
   PubMed Web of Science ®Google Scholar
• Taylor MJ, Charman T, Ronald A. Where are the strongest associations between autistic traits and traits of ADHD? evidence from a community-based twin study. Eur Child Adolesc Psychiatry. 2015;24(9):1129–1138.
   PubMed Web of Science ®Google Scholar
• Pinto R, Rijsdijk F, Ronald A, et al. The genetic overlap of attention-deficit/hyperactivity disorder and autistic-like traits: an investigation of individual symptom scales and cognitive markers. J Abnorm Child Psychol. 2016;44:335–345.
   PubMed Web of Science ®Google Scholar
• Polderman TJ, Hoekstra RA, Vinkhuyzen AAE, et al. Attentional switching forms a genetic link between attention problems and autistic traits in adults. Psychol Med. 2013;43(9):1985–1996.
   PubMed Web of Science ®Google Scholar
• Riley KN, Catalano LM, Bernat JA, et al. Recurrent deletions and duplications of chromosome 2q11.2 and 2q13 are associated with variable outcomes. Am J Med Genet A. 2015;167(11):2664–2673.
   Web of Science ®Google Scholar
• Hu J, Liao J, Sathanoori M, et al. CNTN6 copy number variations in 14 patients: a possible candidate gene for neurodevelopmental and neuropsychiatric disorders. J Neurodev Disord. 2015;7(1):26.
   PubMed Web of Science ®Google Scholar
• Polan MB, Pastore MT, Steingass K, et al. Neurodevelopmental disorders among individuals with duplication of 4p13 to 4p12 containing a GABAA receptor subunit gene cluster. Eur J Hum Genet. 2014;22(1):105–109.
   PubMed Web of Science ®Google Scholar
• Mervis CB, Klein-Tasman BP, Huffman MJ, et al. Children with 7q11.23 duplication syndrome: psychological characteristics. Am J Med Genet A. 2015;167(7):1436–1450.
   PubMed Web of Science ®Google Scholar
• Hu J, Sathanoori M, Kochmar S, et al. A novel maternally inherited 8q24.3 and a rare paternally inherited 14q23.3 CNVs in a family with neurodevelopmental disorders. Am J Med Genet A. 2015;167A(8):1921–1926.
   PubMed Web of Science ®Google Scholar
• Tropeano M, Ahn JW, Dobson RJB, et al. Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders. PLoS One. 2013;8(4):e61365.
   Google Scholar
• Poot M, Verrijn Stuart AA, van Daalen E, et al. Variable behavioural phenotypes of patients with monosomies of 15q26 and a review of 16 cases. Eur J Med Genet. 2013;56(7):346–350.
   PubMed Web of Science ®Google Scholar
• Ross JL, Tartaglia N, Merry DE, et al. Behavioral phenotypes in males with XYY and possible role of increased NLGN4Y expression in autism features. Genes Brain Behav. 2015;14(2):137–144.
   PubMed Web of Science ®Google Scholar
• Ross JL, Roeltgen DP, Kushner H, et al. Behavioral and social phenotypes in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome. Pediatrics. 2012;129(4):769–778.
   PubMed Web of Science ®Google Scholar
• Williams NM, Franke B, Mick E, et al. Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry. 2012;169(2):195–204.
   PubMed Web of Science ®Google Scholar
• Marshall CR, Scherer SW. Detection and characterization of copy number variation in autism spectrum disorder. Methods Mol Biol. 2012;838:115–135.
   PubMedGoogle Scholar
• Bertran M, Tagle FP, Irarrazaval M. Psychiatric manifestations of 22q11.2 deletion syndrome: a literature review [Internet]. Neurologia. 2015. doi:10.1016/j.nrl.2015.07.007. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/?term=tagle+bertran
   PubMedGoogle Scholar
• Swillen A, McDonald-McGinn D. Developmental trajectories in 22q11.2 deletion. Am J Med Genet C Semin Med Genet. 2015;169(2):172–181.
   PubMed Web of Science ®Google Scholar
• Tang KL, Antshel KM, Fremont WP, et al. Behavioral and psychiatric phenotypes in 22q11.2 deletion syndrome. J Dev Behav Pediatr. 2015;36(8):639–650.
   PubMed Web of Science ®Google Scholar
• Lowther C, Costain G, Stavropoulos DJ, et al. Delineating the 15q13.3 microdeletion phenotype: a case series and comprehensive review of the literature. Genet Med. 2015;17(2):149–157.
   PubMed Web of Science ®Google Scholar
• Cox DM, Butler MG. The 15q11.2 BP1-BP2 microdeletion syndrome: a review. Int J Mol Sci. 2015;16(2):4068–4082.
   PubMed Web of Science ®Google Scholar
• Vanlerberghe C, Petit F, Malan V, et al. 15q11.2 microdeletion (BP1-BP2) and developmental delay, behaviour issues, epilepsy and congenital heart disease: a series of 52 patients. Eur J Med Genet. 2015;58(3):140–147.
   PubMed Web of Science ®Google Scholar
• Hadley D, Wu ZL, Kao C, et al. The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism. Nat Commun. 2014;5:4074.
   PubMed Web of Science ®Google Scholar
• Martin J, Cooper M, Hamshere ML, et al. Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants. J Am Acad Child Adolesc Psychiatry. 2014;53(7):761–770.e26.
   Web of Science ®Google Scholar
• Smoller JW, Ripke S, Lee PH, et al. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381(9875):1371–1379.
   PubMed Web of Science ®Google Scholar
• Cristino AS, Williams SM, Hawi Z, et al. Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system. Mol Psychiatry. 2014;19(3):294–301.
   PubMed Web of Science ®Google Scholar
• Lotan A, Fenckova M, Bralten J, et al. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders. Front Neurosci. 2014;8:331.
   PubMed Web of Science ®Google Scholar
• Rivero O, Selten MM, Sich S, et al. Cadherin-13, a risk gene for ADHD and comorbid disorders, impacts GABAergic function in hippocampus and cognition. Transl Psychiatry. 2015;5:e655.
   Google Scholar
• Crepel A, De Wolf V, Brison N, et al. Association of CDH11 with non-syndromic ASD. Am J Med Genet B Neuropsychiatr Genet. 2014;165B(5):391–398.
   PubMed Web of Science ®Google Scholar
• Poot M. Connecting the CNTNAP2 networks with neurodevelopmental disorders. Mol Syndromol. 2015;6(1):7–22.
   PubMedGoogle Scholar
• Lionel AC, Tammimies K, Vaags AK, et al. Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes. Hum Mol Genet. 2014;23(10):2752–2768.
   PubMed Web of Science ®Google Scholar
• Iqbal Z, Vandeweyer G, van der Voet M, et al. Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders. Hum Mol Genet. 2013;22(10):1960–1970.
   PubMed Web of Science ®Google Scholar
• Curran S, Ahn JW, Grayton H, et al. NRXN1 deletions identified by array comparative genome hybridisation in a clinical case series – further understanding of the relevance of NRXN1 to neurodevelopmental disorders. J Mol Psychiatry. 2013;1(1):4.
   PubMedGoogle Scholar
• Esclassan F, Francois J, Phillips KG, et al. Phenotypic characterization of nonsocial behavioral impairment in neurexin 1α knockout rats. Behav Neurosci. 2015;129(1):74–85.
   PubMed Web of Science ®Google Scholar
• Camacho-Garcia RJ, Planelles MI, Margalef M, et al. Mutations affecting synaptic levels of neurexin-1β in autism and mental retardation. Neurobiol Dis. 2012;47(1):135–143.
   PubMed Web of Science ®Google Scholar
• Shang L, Cho MT, Retterer K, et al. Mutations in ARID2 are associated with intellectual disabilities. Neurogenetics. 2015;16(4):307–314.
   PubMed Web of Science ®Google Scholar
• Rasmussen MB, Nielsen JV, Lourenço CM, et al. Neurodevelopmental disorders associated with dosage imbalance of ZBTB20 correlate with the morbidity spectrum of ZBTB20 candidate target genes. J Med Genet. 2014;51(9):605–613.
   PubMed Web of Science ®Google Scholar
• Lozano R, Rosero CA, Hagerman RJ. Fragile X spectrum disorders. Intractable Rare Dis Res. 2014;3(4):134–146.
   PubMedGoogle Scholar
• Aoki Y, Cortese S. Mitochondrial aspartate/glutamate carrier SLC25A12 and autism spectrum disorder: a meta-analysis [Internet]. Mol Neurobiol. 2015 Feb 10. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25663199
   PubMedGoogle Scholar
• Wagle M, Holder J. Exonic deletion of SLC9A9 in autism with epilepsy (P4. 338). Neurology. 2014;82(10 Supplement):P4. 338–P4. 338.
   Google Scholar
• Zayats T, Athanasiu L, Sonderby I, et al. Genome-wide analysis of attention deficit hyperactivity disorder in norway. PLoS One. 2015;10(4):e0122501.
   Web of Science ®Google Scholar
• Wagle M, Holder J. Exonic deletion of SLC9A9 in autism with epilepsy. Neurology. 2014;82(p4):338.
   Google Scholar
• Kondapalli KC, Hack A, Schushan M, et al. Functional evaluation of autism-associated mutations in NHE9. Nat Commun. 2013;4:2510.
   PubMed Web of Science ®Google Scholar
• Hovey D, Zettergren A, Jonsson L, et al. Associations between oxytocin-related genes and autistic-like traits. Soc Neurosci. 2014;9(4):378–386.
   PubMed Web of Science ®Google Scholar
• Taurines R, Schwenck C, Lyttwin B, et al. Oxytocin plasma concentrations in children and adolescents with autism spectrum disorder: correlation with autistic symptomatology. Atten Defic Hyperact Disord. 2014;6(3):231–239.
   PubMedGoogle Scholar
• Tamm G, Kreegipuu K, Harro J. Perception of emotion in facial stimuli: the interaction of ADRA2A and COMT genotypes, and sex. Prog Neuropsychopharmacol Biol Psychiatry. 2016;64:87–95.
   PubMed Web of Science ®Google Scholar
• Karam RA, Rezk NA, Abdelrahman HM, et al. Catechol-O-methyltransferase Val158Met polymorphism and hyperactivity symptoms in Egyptian children with autism spectrum disorder. Res Dev Disabil. 2013;34(7):2092–2097.
   PubMed Web of Science ®Google Scholar
• Antshel KM, Zhang-James Y, Faraone SV. The comorbidity of ADHD and autism spectrum disorder. Expert Rev Neurother. 2013;13(10):1117–1128.
   PubMed Web of Science ®Google Scholar
• Oerlemans AM, Burmanje MJ, Franke B, et al. Identifying unique versus shared pre- and perinatal risk factors for ASD and ADHD using a simplex-multiplex stratification [Internet]. J Abnorm Child Psychol. 2015 Oct 14. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26466830
   PubMedGoogle Scholar
• Curran EA, Cryan JF, Kenny LC, et al. Obstetrical mode of delivery and childhood behavior and psychological development in a British cohort. J Autism Dev Disord. 2016;46(2):603–614.
   PubMed Web of Science ®Google Scholar
• Mostafavi Abdolmaleky H. Horizons of psychiatric genetics and epigenetics: where are we and where are we heading? Iran J Psychiatry Behav Sci. 2014;8(3):1–10.
   PubMedGoogle Scholar
• Kiser DP, Rivero O, Lesch K-P. Annual research review: the (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing–unveiling the dark matter. J Child Psychol Psychiatry. 2015;56(3):278–295.
   PubMed Web of Science ®Google Scholar
• Babenko O, Kovalchuk I, Metz GA. Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health. Neurosci Biobehav Rev. 2015;48:70–91.
   PubMed Web of Science ®Google Scholar
• Lim L, Chantiluke K, Cubillo AI, et al. Disorder-specific grey matter deficits in attention deficit hyperactivity disorder relative to autism spectrum disorder. Psychol Med. 2015;45(5):965–976.
   PubMed Web of Science ®Google Scholar
• Shaw P, Malek M, Watson B, et al. Development of cortical surface area and gyrification in attention-deficit/hyperactivity disorder. Biol Psychiatry. 2012;72(3):191–197.
   PubMed Web of Science ®Google Scholar
• Shaw P, Eckstrand K, Sharp W, et al. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci U S A. 2007;104(49):19649–19654.
   PubMed Web of Science ®Google Scholar
• Bernard JA, Seidler RD. Cerebellar contributions to visuomotor adaptation and motor sequence learning: an ALE meta-analysis. Front Hum Neurosci. 2013;7:27.
   PubMed Web of Science ®Google Scholar
• Stoodley CJ, Schmahmann JD. Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage. 2009;44(2):489–501.
   PubMed Web of Science ®Google Scholar
• Pelphrey KA, Viola RJ, McCarthy G. When strangers pass: processing of mutual and averted social gaze in the superior temporal sulcus. Psychol Sci. 2004;15(9):598–603.
   PubMed Web of Science ®Google Scholar
• Eyler LT, Pierce K, Courchesne E. A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism. Brain. 2012;135(Pt 3):949–960.
   PubMed Web of Science ®Google Scholar
• O’Dwyer L, Tanner C, van Dongen EV, et al. Brain volumetric correlates of autism spectrum disorder symptoms in attention deficit/hyperactivity disorder. PLoS One. 2014;9(6):e101130.
   PubMed Web of Science ®Google Scholar
• Hampshire A, Chamberlain SR, Monti MM, et al. The role of the right inferior frontal gyrus: inhibition and attentional control. Neuroimage. 2010;50(3):1313–1319.
   PubMed Web of Science ®Google Scholar
• Poldrack RA, Wagner AD, Prull MW, et al. Functional specialization for semantic and phonological processing in the left inferior prefrontal cortex. Neuroimage. 1999;10(1):15–35.
   PubMed Web of Science ®Google Scholar
• Geurts HM, Ridderinkhof KR, Scholte HS. The relationship between grey-matter and ASD and ADHD traits in typical adults. J Autism Dev Disord. 2013;43(7):1630–1641.
   PubMed Web of Science ®Google Scholar
• Talati A, Hirsch J. Functional specialization within the medial frontal gyrus for perceptual go/no-go decisions based on “what,” “when,” and “where” related information: an fMRI study. J Cogn Neurosci. 2005;17(7):981–993.
   PubMed Web of Science ®Google Scholar
• Cooper M, Thapar A, Jones DK. White matter microstructure predicts autistic traits in attention-deficit/hyperactivity disorder. J Autism Dev Disord. 2014;44(11):2742–2754.
   PubMed Web of Science ®Google Scholar
• Cooper M, Thapar A, Jones DK. ADHD severity is associated with white matter microstructure in the subgenual cingulum. Neuroimage Clin. 2015;7:653–660.
   PubMedGoogle Scholar
• Dougherty CC, Evans DW, Myers SM, et al. A comparison of structural brain imaging findings in autism spectrum disorder and attention-deficit hyperactivity disorder [Internet]. Neuropsychol Rev. 2015 Oct 19. [Epub ahead of print]. [cited 2016 Feb 7]. Avilable from: http://www.ncbi.nlm.nih.gov/pubmed/26482248
   PubMedGoogle Scholar
• Chantiluke K, Barrett N, Giampietro V, et al. Inverse fluoxetine effects on inhibitory brain activation in non-comorbid boys with ADHD and with ASD. Psychopharmacology (Berl). 2015;232(12):2071–2082.
   PubMed Web of Science ®Google Scholar
• Xiao T, Xiao Z, Ke X, et al. Response inhibition impairment in high functioning autism and attention deficit hyperactivity disorder: evidence from near-infrared spectroscopy data. PLoS One. 2012;7(10):e46569.
   PubMed Web of Science ®Google Scholar
• Christakou A, Murphy CM, Chantiluke K, et al. Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism. Mol Psychiatry. 2013;18(2):236–244.
   PubMed Web of Science ®Google Scholar
• Grayson DS, Ray S, Carpenter S, et al. Structural and functional rich club organization of the brain in children and adults. PLoS One. 2014;9(2):e88297.
   PubMed Web of Science ®Google Scholar
• Ray S, Miller M, Karalunas S, et al. Structural and functional connectivity of the human brain in autism spectrum disorders and attention-deficit/hyperactivity disorder: a rich club-organization study. Hum Brain Mapp. 2014;35(12):6032–6048.
   PubMed Web of Science ®Google Scholar
• Di Martino A, Zuo X-N, Kelly C, et al. Shared and distinct intrinsic functional network centrality in autism and attention-deficit/hyperactivity disorder. Biol Psychiatry. 2013;74(8):623–632.
   PubMed Web of Science ®Google Scholar
• Nigg JT, Blaskey LG, Huang-Pollock CL, et al. Neuropsychological executive functions and DSM-IV ADHD subtypes. J Am Acad Child Adolesc Psychiatry. 2002;41(1):59–66.
   PubMed Web of Science ®Google Scholar
• Barkley RA. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull. 1997;121(1):65–94.
   PubMed Web of Science ®Google Scholar
• Russell J. Autism as an executive disorder. New York (NY): Oxford University Press; 1997.
   Google Scholar
• Ozonoff S, Jensen J. Brief report: specific executive function profiles in three neurodevelopmental disorders. J Autism Dev Disord. 1999;29(2):171–177.
   PubMed Web of Science ®Google Scholar
• Hill EL. Executive dysfunction in autism. Trends Cogn Sci. 2004;8(1):26–32.
   PubMed Web of Science ®Google Scholar
• Lawson RA, Papadakis AA, Higginson CI, et al. Everyday executive function impairments predict comorbid psychopathology in autism spectrum and attention deficit hyperactivity disorders. Neuropsychology. 2015;29(3):445–453.
   PubMed Web of Science ®Google Scholar
• Biscaldi M, Rauh R, Müller C, et al. Identification of neuromotor deficits common to autism spectrum disorder and attention deficit/hyperactivity disorder, and imitation deficits specific to autism spectrum disorder. Eur Child Adolesc Psychiatry. 2015;24(12):1497–1507.
   PubMed Web of Science ®Google Scholar
• Sanz-Cervera P, Pastor-Cerezuela G, Fernández-Andrés M-I, et al. Sensory processing in children with Autism Spectrum Disorder: relationship with non-verbal IQ, autism severity and Attention Deficit/Hyperactivity Disorder symptomatology. Res Dev Disabil. 2015;45–46:188–201.
   PubMed Web of Science ®Google Scholar
• Mattard-Labrecque C, Ben Amor L, Couture MM. Children with autism and attention difficulties: a pilot study of the association between sensory, motor, and adaptive behaviors. J Can Acad Child Adolesc Psychiatry. 2013;22(2):139–146.
   PubMedGoogle Scholar
• Unterrainer JM, Rauh R, Rahm B, et al. Development of planning in children with high-functioning autism spectrum disorders and/or attention deficit/hyperactivity disorder [Internet]. Autism Res. 2015 doi:10.1002/aur.1574. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26442805
   PubMedGoogle Scholar
• Tye C, Asherson P, Ashwood KL, et al. Attention and inhibition in children with ASD, ADHD and co-morbid ASD + ADHD: an event-related potential study. Psychol Med. 2014;44(5):1101–1116.
   PubMed Web of Science ®Google Scholar
• Andersen PN, Hovik KT, Skogli EW, et al. Symptoms of ADHD in children with high-functioning autism are related to impaired verbal working memory and verbal delayed recall. PLoS One. 2013;8(5):e64842.
   PubMed Web of Science ®Google Scholar
• Adamo N, Huo L, Adelsberg S, et al. Response time intra-subject variability: commonalities between children with autism spectrum disorders and children with ADHD. Eur Child Adolesc Psychiatry. 2014;23(2):69–79.
   PubMed Web of Science ®Google Scholar
• Lundervold AJ, Stickert M, Hysing M, et al. Attention deficits in children with combined autism and ADHD: a CPT study [Internet]. J Atten Disord. 2012. Aug 31 [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22940852
   Google Scholar
• Anholt GE, Cath DC, van Oppen P, et al. Autism and ADHD symptoms in patients with OCD: are they associated with specific OC symptom dimensions or OC symptom severity? J Autism Dev Disord. 2010;40(5):580–589.
   PubMed Web of Science ®Google Scholar
• Nyden A, Niklasson L, Stahlberg O, et al. Adults with autism spectrum disorders and ADHD neuropsychological aspects. Res Dev Disabil. 2010;31(6):1659–1668.
   PubMed Web of Science ®Google Scholar
• Tye C, Battaglia M, Bertoletti E, et al. Altered neurophysiological responses to emotional faces discriminate children with ASD, ADHD and ASD + ADHD. Biol Psychol. 2014;103:125–134.
   PubMed Web of Science ®Google Scholar
• Yerys BE, Kenworthy L, Jankowski KF, et al. Separate components of emotional go/no-go performance relate to autism versus attention symptoms in children with autism. Neuropsychology. 2013;27(5):537–545.
   PubMed Web of Science ®Google Scholar
• Oerlemans AM, van der Meer JMJ, van Steijn DJ, et al. Recognition of facial emotion and affective prosody in children with ASD (+ADHD) and their unaffected siblings. Eur Child Adolesc Psychiatry. 2014;23(5):257–271.
   PubMed Web of Science ®Google Scholar
• Jarrold W, Mundy P, Gwaltney M, et al. Social attention in a virtual public speaking task in higher functioning children with autism. Autism Res. 2013;6(5):393–410.
   PubMed Web of Science ®Google Scholar
• Buhler E, Bachmann C, Goyert H, et al. Differential diagnosis of autism spectrum disorder and attention deficit hyperactivity disorder by means of inhibitory control and ‘theory of mind’. J Autism Dev Disord. 2011;41(12):1718–1726.
   PubMed Web of Science ®Google Scholar
• Baribeau DA, Doyle-Thomas KAR, Dupuis A, et al. Examining and comparing social perception abilities across childhood-onset neurodevelopmental disorders. J Am Acad Child Adolesc Psychiatry. 2015;54(6):479–486.e1.
   PubMed Web of Science ®Google Scholar
• Rao PA, Landa RJ. Association between severity of behavioral phenotype and comorbid attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders. Autism. 2014;18(3):272–280.
   PubMed Web of Science ®Google Scholar
• Scheres A, Tontsch C, Thoeny AL. Steep temporal reward discounting in ADHD-Combined type: acting upon feelings. Psychiatry Res. 2013;209(2):207–213.
   PubMed Web of Science ®Google Scholar
• Scheres A, Tontsch C, Thoeny AL, et al. Temporal reward discounting in attention-deficit/hyperactivity disorder: the contribution of symptom domains, reward magnitude, and session length. Biol Psychiatry. 2010;67(7):641–648.
   PubMed Web of Science ®Google Scholar
• Demurie E, Roeyers H, Baeyens D, et al. Domain-general and domain-specific aspects of temporal discounting in children with ADHD and autism spectrum disorders (ASD): a proof of concept study. Res Dev Disabil. 2013;34(6):1870–1880.
   PubMed Web of Science ®Google Scholar
• Goldstein S, Schwebach AJ. The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: results of a retrospective chart review. J Autism Dev Disord. 2004;34(3):329–339.
   PubMed Web of Science ®Google Scholar
• Jensen VK, Larrieu JA, Mack KK. Differential diagnosis between attention-deficit/hyperactivity disorder and pervasive developmental disorder–not otherwise specified. Clin Pediatr (Phila). 1997;36(10):555–561.
   PubMed Web of Science ®Google Scholar
• Luteijn EF, Serra M, Jackson S, et al. How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD. Eur Child Adolesc Psychiatry. 2000;9(3):168–179.
   PubMed Web of Science ®Google Scholar
• Hattori J, Ogino T, Abiru K, et al. Are pervasive developmental disorders and attention-deficit/hyperactivity disorder distinct disorders? Brain Dev. 2006;28(6):371–374.
   PubMed Web of Science ®Google Scholar
• Yoshida Y, Uchiyama T. The clinical necessity for assessing Attention Deficit/Hyperactivity Disorder (AD/HD) symptoms in children with high-functioning Pervasive Developmental Disorder (PDD). Eur Child Adolesc Psychiatry. 2004;13(5):307–314.
   PubMed Web of Science ®Google Scholar
• Miller M, Iosif A-M, Young GS, et al. School-age outcomes of infants at risk for autism spectrum disorder [Internet]. Autism Res. 2015. doi:10.1002/aur.1572. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26451968
   PubMedGoogle Scholar
• Buitelaar JK, van der Wees M, Swaab-Barneveld H, et al. Theory of mind and emotion-recognition functioning in autistic spectrum disorders and in psychiatric control and normal children. Dev Psychopathol. 1999;11(1):39–58.
   PubMed Web of Science ®Google Scholar
• Mulligan A, Anney RJL, O’Regan M, et al. Autism symptoms in Attention-Deficit/Hyperactivity Disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders. J Autism Dev Disord. 2009;39(2):197–209.
   PubMed Web of Science ®Google Scholar
• Santosh PJ, Baird G, Pityaratstian N, et al. Impact of comorbid autism spectrum disorders on stimulant response in children with attention deficit hyperactivity disorder: a retrospective and prospective effectiveness study. Child Care Health Dev. 2006;32(5):575–583.
   PubMed Web of Science ®Google Scholar
• Reiersen AM, Constantino JN, Volk HE, et al. Autistic traits in a population-based ADHD twin sample. J Child Psychol Psychiatry. 2007;48(5):464–472.
   PubMed Web of Science ®Google Scholar
• Green JL, Rinehart N, Anderson V, et al. Autism spectrum disorder symptoms in children with ADHD: A community-based study. Res Dev Disabil. 2015;47:175–184.
   PubMed Web of Science ®Google Scholar
• Ames CS, White SJ. Are ADHD traits dissociable from the autistic profile? Links between cognition and behaviour. J Autism Dev Disord. 2011;41(3):357–363.
   PubMed Web of Science ®Google Scholar
• Miodovnik A, Harstad E, Sideridis G, et al. Timing of the diagnosis of attention-deficit/hyperactivity disorder and autism spectrum disorder. Pediatrics. 2015;136(4):e830–837.
   PubMed Web of Science ®Google Scholar
• McQuade JD, Hoza B. Peer problems in attention deficit hyperactivity disorder: current status and future directions. Dev Disabil Res Rev. 2008;14(4):320–324.
   PubMed Web of Science ®Google Scholar
• Grzadzinski R, Di Martino A, Brady E, et al. Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD? J Autism Dev Disord. 2011;41:1178–1191.
   PubMed Web of Science ®Google Scholar
• Sung V, Hiscock H, Sciberras E, et al. Sleep problems in children with attention-deficit/hyperactivity disorder: prevalence and the effect on the child and family. Arch Pediatr Adolesc Med. 2008;162(4):336–342.
   PubMed Web of Science ®Google Scholar
• Edvinsson D, Lindström E, Bingefors K, et al. Gender differences of axis I and II comorbidity in subjects diagnosed with attention-deficit hyperactivity disorder as adults. Acta Neuropsychiatr. 2013;25(3):165–174.
   PubMed Web of Science ®Google Scholar
• Johnston K, Dittner A, Bramham J, et al. Attention deficit hyperactivity disorder symptoms in adults with autism spectrum disorders. Autism Res. 2013;6(4):225–236.
   PubMed Web of Science ®Google Scholar
• Turygin N, Matson JL, Tureck K. The relationship of attention-deficit hyperactivity disorder and autism spectrum disorder to adaptive skills in young children. Dev Neurorehabil. 2015;18(5):317–321.
   PubMed Web of Science ®Google Scholar
• Sikora DM, Vora P, Coury DL, et al. Attention-deficit/hyperactivity disorder symptoms, adaptive functioning, and quality of life in children with autism spectrum disorder. Pediatrics. 2012;130(Suppl 2):S91–97.
   Google Scholar
• Ashwood KL, Tye C, Azadi B, et al. Brief report: adaptive functioning in children with ASD, ADHD and ASD + ADHD. J Autism Dev Disord. 2015;45:2235–2242.
   PubMed Web of Science ®Google Scholar
• Mattard-Labrecque C, Ben Amor L, Couture MM. Children with autism and attention difficulties: a pilot study of the association between sensory, motor, and adaptive behaviors. J Can Acad Adolesc Psychiatry. 2013;22(2):139–146.
   PubMedGoogle Scholar
• Yerys BE, Wallace GL, Sokoloff JL, et al. Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders. Autism Res. 2009;2(6):322–333.
   PubMed Web of Science ®Google Scholar
• Goldin RL, Matson JL, Tureck K, et al. A comparison of tantrum behavior profiles in children with ASD, ADHD and comorbid ASD and ADHD. Res Dev Disabil. 2013;34(9):2669–2675.
   PubMed Web of Science ®Google Scholar
• Jang J, Matson JL, Williams LW, et al. Rates of comorbid symptoms in children with ASD, ADHD, and comorbid ASD and ADHD. Res Dev Disabil. 2013;34(8):2369–2378.
   PubMed Web of Science ®Google Scholar
• Craig F, Lamanna AL, Margari F, et al. Overlap between autism spectrum disorders and attention deficit hyperactivity disorder: searching for distinctive/common clinical features. Autism Res. 2015;8(3):328–337.
   PubMed Web of Science ®Google Scholar
• Flouri E, Midouhas E, Charman T, et al. Poverty and the growth of emotional and conduct problems in children with autism with and without comorbid ADHD. J Autism Dev Disord. 2015;45(9):2928–2938.
   PubMed Web of Science ®Google Scholar
• Kerekes N, Brändström S, Lundström S, et al. ADHD, autism spectrum disorder, temperament, and character: phenotypical associations and etiology in a Swedish childhood twin study. Compr Psychiatry. 2013;54(8):1140–1147.
   PubMed Web of Science ®Google Scholar
• Wentz E, Nyden A, Krevers B. Development of an internet-based support and coaching model for adolescents and young adults with ADHD and autism spectrum disorders: a pilot study. Eur Child Adolesc Psychiatry. 2012;21(11):611–622.
   PubMed Web of Science ®Google Scholar
• De Vries M, Prins PJM, Schmand BA, et al. Working memory and cognitive flexibility-training for children with an autism spectrum disorder: a randomized controlled trial. J Child Psychol Psychiatry. 2015;56(5):566–576.
   PubMed Web of Science ®Google Scholar
• Liu X, Hubbard JA, Fabes RA, et al. Sleep disturbances and correlates of children with autism spectrum disorders. Child Psychiatry Hum Dev. 2006;37(2):179–191.
   PubMed Web of Science ®Google Scholar
• Virring A, Lambek R, Jennum PJ, et al. Sleep problems and daily functioning in children with ADHD: an investigation of the role of impairment, ADHD presentations, and psychiatric comorbidity [Internet]. J Atten Disord. 2014. pii:1087054714542001. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25015581
   PubMedGoogle Scholar
• Papadopoulos N, Sciberras E, Hiscock H, et al. The efficacy of a brief behavioral sleep intervention in school-aged children with ADHD and comorbid autism spectrum disorder [Internet]. J Atten Disord. 2015. pii:1087054714568565. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25646022
   Google Scholar
• Pearson DA, Santos CW, Aman MG, et al. Effects of extended release methylphenidate treatment on ratings of attention-deficit/hyperactivity disorder (ADHD) and associated behavior in children with autism spectrum disorders and ADHD symptoms. J Child Adolesc Psychopharmacol. 2013;23(5):337–351.
   PubMed Web of Science ®Google Scholar
• Reichow B, Volkmar FR, Bloch MH. Systematic review and meta-analysis of pharmacological treatment of the symptoms of attention-deficit/hyperactivity disorder in children with pervasive developmental disorders. J Autism Dev Disord. 2013;43(10):2435–2441.
   PubMed Web of Science ®Google Scholar
• Faraone SV, Buitelaar J. Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis. Eur Child Adolesc Psychiatry. 2010;19(4):353–364.
   PubMed Web of Science ®Google Scholar
• Harfterkamp M, Buitelaar JK, Minderaa RB, et al. Long-term treatment with atomoxetine for attention-deficit/hyperactivity disorder symptoms in children and adolescents with autism spectrum disorder: an open-label extension study. J Child Adolesc Psychopharmacol. 2013;23(3):194–199.
   PubMed Web of Science ®Google Scholar
• Harfterkamp M, van de Loo-Neus G, Minderaa RB, et al. A randomized double-blind study of atomoxetine versus placebo for attention-deficit/hyperactivity disorder symptoms in children with autism spectrum disorder. J Am Acad Child Adolesc Psychiatry. 2012;51(7):733–741.
   PubMed Web of Science ®Google Scholar
• Handen BL, Aman MG, Arnold LE, et al. Atomoxetine, parent training, and their combination in children with autism spectrum disorder and attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2015;54(11):905–915.
   PubMed Web of Science ®Google Scholar
• Harfterkamp M, Buitelaar JK, Minderaa RB, et al. Atomoxetine in autism spectrum disorder: no effects on social functioning; some beneficial effects on stereotyped behaviors, inappropriate speech, and fear of change. J Child Adolesc Psychopharmacol. 2014;24(9):481–485.
   PubMed Web of Science ®Google Scholar
• Newcorn JH, Sutton VK, Weiss MD, et al. Clinical responses to atomoxetine in attention-deficit/hyperactivity disorder: the Integrated Data Exploratory Analysis (IDEA) study. J Am Acad Child Adolesc Psychiatry. 2009;48(5):511–518.
   PubMed Web of Science ®Google Scholar
• Harfterkamp M, van der Meer D, van der Loo-Neus G, et al. No evidence for predictors of response to atomoxetine treatment of attention-deficit/hyperactivity disorder symptoms in children and adolescents with autism spectrum disorder. J Child Adolesc Psychopharmacol. 2015;25(4):372–375.
   PubMed Web of Science ®Google Scholar
• Scahill L, McCracken JT, King BH, et al. Extended-release guanfacine for hyperactivity in children with autism spectrum disorder. Am J Psychiatry. 2015;172(12):1197–1206.
   PubMed Web of Science ®Google Scholar
• Golubchik P, Sever J, Weizman A. Reboxetine treatment for autistic spectrum disorder of pediatric patients with depressive and inattentive/hyperactive symptoms: an open-label trial. Clin Neuropharmacol. 2013;36(2):37–41.
   PubMed Web of Science ®Google Scholar
• Logan SL, Carpenter L, Leslie RS, et al. Aberrant behaviors and co-occurring conditions as predictors of psychotropic polypharmacy among children with autism spectrum disorders. J Child Adolesc Psychopharmacol. 2015;25(4):323–336.
   PubMed Web of Science ®Google Scholar
• Logan SL, Carpenter L, Leslie RS, et al. Rates and predictors of adherence to psychotropic medications in children with autism spectrum disorders. J Autism Dev Disord. 2014;44(11):2931–2948.
   PubMed Web of Science ®Google Scholar
• Mire SS, Nowell KP, Kubiszyn T, et al. Psychotropic medication use among children with autism spectrum disorders within the Simons Simplex Collection: are core features of autism spectrum disorder related? Autism. 2014;18(8):933–942.
   PubMed Web of Science ®Google Scholar
• Coury DL, Anagnostou E, Manning-Courtney P, et al. Use of psychotropic medication in children and adolescents with autism spectrum disorders. Pediatrics. 2012;130(Suppl 2):S69–76.
   PubMedGoogle Scholar
• Anderson DK, Liang JW, Lord C. Predicting young adult outcome among more and less cognitively able individuals with autism spectrum disorders. J Child Psychol Psychiatry. 2014;55(5):485–494.
   PubMed Web of Science ®Google Scholar
• Smith T, Iadarola S. Evidence base update for autism spectrum disorder. J Clin Child Adolesc Psychol. 2015;44(6):897–922.
   PubMed Web of Science ®Google Scholar
• Wilson BJ, Manangan CN, Dauterman HA, et al. ADHD symptoms moderate the relation between ASD status and internalizing symptoms in 3-6-year-old children. J Autism Dev Disord. 2014;44(6):1347–1356.
   PubMed Web of Science ®Google Scholar
• Williford AP, Shelton TL. Behavior management for preschool-aged children. Child Adolesc Psychiatr Clin N Am. 2014;23(4):717–730.
   PubMed Web of Science ®Google Scholar
• Greenhill L, Kollins S, Abikoff H, et al. Efficacy and safety of immediate-release methylphenidate treatment for preschoolers with ADHD. J Am Acad Child Adolesc Psychiatry. 2006;45(11):1284–1293.
   PubMed Web of Science ®Google Scholar
• DuPaul GJ, Gormley MJ, Laracy SD. School-based interventions for elementary school students with ADHD. Child Adolesc Psychiatr Clin N Am. 2014;23(4):687–697.
   PubMed Web of Science ®Google Scholar
• Mahajan R, Bernal MP, Panzer R, et al. Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders. Pediatrics. 2012;130(Suppl 2):S125–138.
   PubMed Web of Science ®Google Scholar
• Subcommittee on Attention-Deficit/Hyperactivity Disorder, Steering Committee on Quality Improvement and Management, Wolraich M, et al. ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics. 2011;128(5):1007–1022.
   PubMed Web of Science ®Google Scholar
• Pfiffner LJ, Haack LM. Behavior management for school-aged children with ADHD. Child Adolesc Psychiatr Clin N Am. 2014;23(4):731–746.
   PubMed Web of Science ®Google Scholar
• Dababnah S, Parish SL. Feasibility of an empirically based program for parents of preschoolers with autism spectrum disorder. Autism. 2016;20(1):85–95. doi:10.1177/1362361314568900.
   PubMed Web of Science ®Google Scholar
• Roberts D, Pickering N. Parent training programme for autism spectrum disorders: an evaluation. Community Pract. 2010;83(10):27–30.
   PubMedGoogle Scholar
• Roux G, Sofronoff K, Sanders M. A randomized controlled trial of group Stepping Stones Triple P: a mixed-disability trial. Fam Process. 2013;52(3):411–424.
   PubMed Web of Science ®Google Scholar
• Hodgetts S, Savage A, McConnell D. Experience and outcomes of stepping stones triple P for families of children with autism. Res Dev Disabil. 2013;34(9):2572–2585.
   PubMed Web of Science ®Google Scholar
• Midouhas E, Yogaratnam A, Flouri E, et al. Psychopathology trajectories of children with autism spectrum disorder: the role of family poverty and parenting. J Am Acad Child Adolesc Psychiatry. 2013;52(10):1057–1065.e1.
   PubMed Web of Science ®Google Scholar
• Mandy W, Roughan L, Skuse D. Three dimensions of oppositionality in autism spectrum disorder. J Abnorm Child Psychol. 2014;42(2):291–300.
   PubMed Web of Science ®Google Scholar
• Cadman T, Eklund H, Howley D, et al. Caregiver burden as people with autism spectrum disorder and attention-deficit/hyperactivity disorder transition into adolescence and adulthood in the United Kingdom. J Am Acad Child Adolesc Psychiatry. 2012;51(9):879–888.
   PubMed Web of Science ®Google Scholar
• van Steijn DJ, Oerlemans AM, van Aken MAG, et al. The reciprocal relationship of ASD, ADHD, depressive symptoms and stress in parents of children with ASD and/or ADHD. J Autism Dev Disord. 2014;44(5):1064–1076.
   PubMed Web of Science ®Google Scholar
• van Steijn DJ, Oerlemans AM, van Aken MAG, et al. Match or mismatch? Influence of parental and offspring ASD and ADHD symptoms on the parent-child relationship. J Autism Dev Disord. 2013;43(8):1935–1945.
   PubMed Web of Science ®Google Scholar
• Huang A, Seshadri K, Matthews TA, et al. Parental perspectives on use, benefits, and physician knowledge of complementary and alternative medicine in children with autistic disorder and attention-deficit/hyperactivity disorder. J Altern Complement Med. 2013;19(9):746–750.
   PubMed Web of Science ®Google Scholar
• Wong HH, Smith RG. Patterns of complementary and alternative medical therapy use in children diagnosed with autism spectrum disorders. J Autism Dev Disord. 2006;36(7):901–909.
   PubMed Web of Science ®Google Scholar
• Liptak GS, Orlando M, Yingling JT, et al. Satisfaction with primary health care received by families of children with developmental disabilities. J Pediatr Health Care. 2006;20(4):245–252.
   PubMedGoogle Scholar
• Engelhardt CR, Mazurek MO, Sohl K. Media use and sleep among boys with autism spectrum disorder, ADHD, or typical development. Pediatrics. 2013;132(6):1081–1089.
   PubMed Web of Science ®Google Scholar
• Evans SW, Langberg JM, Schultz BK, et al. Evaluation of a school-based treatment program for young adolescents with ADHD. J Consult Clin Psychol. 2016;84(1):15–30. doi:10.1037/ccp0000057.
   PubMed Web of Science ®Google Scholar
• Vidal R, Castells J, Richarte V, et al. Group therapy for adolescents with attention-deficit/hyperactivity disorder: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry. 2015;54(4):275–282.
   PubMed Web of Science ®Google Scholar
• Langberg JM, Epstein JN, Becker SP, et al. Evaluation of the homework, organization, and planning skills (HOPS) intervention for middle school students with ADHD as implemented by school mental health providers. School Psych Rev. 2012;41(3):342–364.
   PubMed Web of Science ®Google Scholar
• Boyer BE, Geurts HM, Prins PJM, et al. Two novel CBTs for adolescents with ADHD: the value of planning skills. Eur Child Adolesc Psychiatry. 2015;24(9):1075–1090.
   PubMed Web of Science ®Google Scholar
• Zablotsky B, Bradshaw CP, Anderson C, et al. The association between bullying and the psychological functioning of children with autism spectrum disorders. J Dev Behav Pediatr. 2013;34(1):1–8.
   PubMed Web of Science ®Google Scholar
• Sterzing PR, Shattuck PT, Narendorf SC, et al. Bullying involvement and autism spectrum disorders: prevalence and correlates of bullying involvement among adolescents with an autism spectrum disorder. Arch Pediatr Adolesc Med. 2012;166(11):1058–1064.
   PubMedGoogle Scholar
• Antshel KM, Polacek C, McMahon M, et al. Comorbid ADHD and anxiety affect social skills group intervention treatment efficacy in children with autism spectrum disorders. J Dev Behav Pediatr. 2011;32(6):439–446.
   PubMed Web of Science ®Google Scholar
• Hatzenbuehler ML, Schwab-Reese L, Ranapurwala SI, et al. Associations between antibullying policies and bullying in 25 states. JAMA Pediatr. 2015;169(10):e152411.
   PubMed Web of Science ®Google Scholar
• Beecham J. Annual research review: child and adolescent mental health interventions: a review of progress in economic studies across different disorders. J Child Psychol Psychiatry. 2014;55(6):714–732.
   PubMed Web of Science ®Google Scholar
• Gargaro BA, Rinehart NJ, Bradshaw JL, et al. Autism and ADHD: how far have we come in the comorbidity debate? Neurosci Biobehav Rev. 2011;35(5):1081–1088.
   PubMed Web of Science ®Google Scholar
• Pennington BF, Ozonoff S. Executive functions and developmental psychopathology. J Child Psychol Psychiatry. 1996;37(1):51–87.
   PubMed Web of Science ®Google Scholar
• Polanczyk GV, Willcutt EG, Salum GA, et al. ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis. Int J Epidemiol. 2014;43(2):434–442.
   PubMed Web of Science ®Google Scholar
• Lundstrom S, Reichenberg A, Anckarsater H, et al. Autism phenotype versus registered diagnosis in Swedish children: prevalence trends over 10 years in general population samples. BMJ. 2015;350:h1961.
   Google Scholar
• Parikh SV, Huniewicz P. E-health: an overview of the uses of the Internet, social media, apps, and websites for mood disorders. Curr Opin Psychiatry. 2015;28(1):13–17.
   PubMed Web of Science ®Google Scholar
• Swineford LB, Thurm A, Baird G, et al. Social (pragmatic) communication disorder: a research review of this new DSM-5 diagnostic category. J Neurodev Disord. 2014;6(1):41.
   PubMed Web of Science ®Google Scholar
• Roullet FI, Wollaston L, Decatanzaro D, et al. Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid. Neuroscience. 2010;170(2):514–522.
   PubMed Web of Science ®Google Scholar
• Tania M, Khan MA, Xia K. Recent advances in animal model experimentation in autism research. Acta Neuropsychiatr. 2014;26(5):264–271.
   PubMed Web of Science ®Google Scholar
• Hara Y, Ago Y, Taruta A, et al. Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism [Internet]. Autism Res. 2015. doi:10.1002/aur.1596. [Epub ahead of print]. [cited 2016 Feb 7]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26714434
   PubMedGoogle Scholar
• Insel T, Cuthbert B, Garvey M, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010;167(7):748–751.
   PubMed Web of Science ®Google Scholar