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Review

Treatment of bipolar depression: focus on pharmacologic therapies

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Pages 69-78 | Published online: 10 Jan 2014

References

  • Mitchell PB, Malhi GS. Bipolar depression: phenomenological overview and clinical characteristics. Bipolar Dis.6, 530–539 (2004).
  • Judd LL, Akiskal HS, Schttler PJ, Endicott J, Maser J, Solomon DA. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch. Gen. Psych.59, 530–537 (2002).
  • Judd LL, Akiskal HS, Schuttler PJ, Coryell W, Endicott J, Maser JD. Prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch. Gen. Psych.60, 261–269 (2003).
  • Bauer MS, Kirk GF, Gavin C, Williford WO. Determinants of functional outcome and healthcare costs in bipolar disorder: a high-intensity follow-up study. J. Affect. Disorders65, 231–241 (2001).
  • Bryant-Comstock L, Stender M, Devercelli G. Healthcare utilization and costs among privately insured patients with bipolar I disorder. Bipolar Dis.6, 398–405 (2002).
  • Altshuler LL, Gitlin MJ, Mintz J, Leight KL, Frye MA. Subsyndromal depression is associated with functional impairment in-patients with bipolar disorder. J. Clin. Psychiatry63, 807–811 (2002).
  • Muller-Oelinghausen B, Berghofer A, Bauer M. Bipolar disorder. Lancet359, 241–247 (2002).
  • Tondo L, Isacsson G, Baldessarini RJ. Suicidal behaviour in bipolar disorder: risk and prevention. CNS Drugs17, 491–511 (2003).
  • Chen Y-W, Dilsaver SC. Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other axis I disorders. Biol. Psychiatry39, 896–899 (1996).
  • Mitchell PB, Slade T, Andrews G. Twelve-month prevalence and disability of DSM-IV bipolar disorder in an Australian general population survey. Psychol. Med.34, 777–785 (2004).
  • Kessler RC, Rubinow DR, Holmes C, Abelson JM, Zhao S. The epidemiology of DSM-III-R bipolar I disorder in a general population survey. Psychol. Med.27, 1079–1080 (1997).
  • Goodwin F, Jamison K. Manic-Depressive Illness. Oxford University Press, NY, USA, 1–938 (1990).
  • Harris EC, Barraclough B. Suicide as an outcome for mental disorders. Br. J. Psychiatry170, 205–228 (1997).
  • Dilsaver SC, Chen Y-W, Swann AC, Shoaib AM, Tsai-Dilsaver Y, Krajewski KJ. Suicidality, panic disorder and psychosis in bipolar depression, depressive-mania and pure-mania. Psych. Res.73, 47–56 (1997).
  • Isometsa ET, Henriksson MM, Aro HM, Lonnqvist JK. Suicide in bipolar disorder in Finland. Am. J. Psychiatry151, 1020–1024 (1994).
  • Lopez P, Mosquera F, de Leon J et al. Suicide attempts in bipolar patients. J. Clin. Psychiatry62, 963–966 (2001).
  • Rihmer Z, Kiss K. Bipolar disorders and suicide behaviour. Bipolar Dis.4, 21–25 (2002).
  • Frankle WG, Perlis RH, Deckersbach T et al. Bipolar depression: relationship between episode length and antidepressant treatment. Psychol. Med.32, 1417–1423 (2002).
  • Crown WH, Finklenstein S, Berndt ER et al. The impact of treatment-resistant depression on healthcare utilization and costs. J. Clin. Psychiatry63, 963–971 (2002).
  • Furukawa TA, Konno W, Morinobu S, Harai H, Kitamura T, Takahashi K. Course and outcome of depressive episodes: comparison between bipolar, unipolar and subthreshold depression. Psychiatry Res.96, 211–220 (2000).
  • Bottlender R, Rudolf D, Jager M, Strauss A, Moller H-J. Are bipolar I depressive patients less responsive to treatment with antidepressants than unipolar depressive patients? Result from a case control study. Eur. Psychiatry17, 200–205 (2002).
  • Zarate CA, Payne JL, Singh J et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol. Psychiatry56, 54–60 (2004).
  • Hadjipavlou G, Mok H, Yatham LN. Pharmacotherapy of bipolar II disorder: a critical review of current evidence. Bipolar Dis.6, 14–25 (2004).
  • Bauer MS, Mitchner L. What is a ‘mood stabiliser’? An evidence-based response. Am. J. Psychiatry161, 13–18 (2004).
  • Gijsman HJ, Geddes JR, Rendell JM, Nolen WA, Goodwin GM. Antidepressants for bipolar depression: a systematic review of randomized, controlled trials. Am. J. Psychiatry161, 1537–1547 (2004).
  • Coryell W, Colomon D, Turvey C et al. The long-term course of rapid-cycling bipolar disorder. Arch. Gen. Psych.60, 914–920 (2003).
  • Malhi GS, Mitchell PB, Salim S. Bipolar depression: management options. CNS Drugs17, 9–25 (2003).
  • Peet M. Induction of mania with selective serotonin re-uptake inhibitors and tricyclic antidepressants. Br. J. Psychiatry164, 549–550 (1994).
  • Bottlender R, Rudolf D, Straub A, Moller H-J. Mood stabilizers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar I depressed patients. J. Affect. Disorders63, 79–83 (2001).
  • Henry C, Sorbara F, Lacoste J, Gindre C, Leboyer M. Antidepressant-induced mania in bipolar patients: identification of risk factors. J. Clin. Psychiatry62, 249–255 (2001).
  • Altshuler L, Suppes T, Black D et al. Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. Am. J. Psychiatry160, 1252–1262 (2003).
  • Royal Australian and New Zealand College of Psychiatrists Clinical Practice Guidelines Team for Bipolar Disorder. Australian and New Zealand clinical practice guidelines for the treatment of bipolar disorder. Aust. NZ J. Psychiatry38, 280–305 (2004).
  • Suppes T, Baldessarini RJ, Faedda GL et al. Risk of recurrence following discontinuation of lithium treatment in bipolar disorder. Arch. Gen. Psych.48, 1082–1088 (1991).
  • Zornberg GL, Pope Jr. HG. Treatment of depression in bipolar disorder: new directions for research.J. Clin. Psychopharmacol.13, 397–408 (1993).
  • Nemeroff CB, Evans DL, Gyulai L et al. Double -blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression. Am. J. Psychiatry158, 906–912 (2001).
  • Daly JJ, Prudic J, Devanand DP et al. ECT in bipolar and unipolar depression: differences in speed of response. Bipolar Disorders3, 95–104 (2001).
  • Ballenger JC, Post RM. carbamazepine in manic-depressive illness: a new treatment. Am. J. Psychiatry137, 782–790 (1980).
  • Post RM, Uhde TW, Roy-Byrne P et al. Antidepressant effects of carbamazepine. Am. J. Psychiatry143, 29–34 (1986).
  • Post RM, Leverich GS, Denicoff KD et al. Alternative approaches to refractory depression in bipolar illness. Depression Anxiety5, 73–83 (1997).
  • Dilsaver SC, Swann SC, Chen Y et al. Treatment of bipolar depression with carbamazepine: results of an open study. Biol. Psychiatry40, 935–937 (1996)
  • Kramlinger KG, Post RM. The addition of lithium to carbamazepine. Arch. Gen. Psych.46, 794–800 (1989).
  • Post RM, Ketter TA, Denicoff K et al. The place of anticonvulsant therapy in bipolar illness. Psychopharmacology128, 115–129 (1996)
  • Young LT, Joffe RT, Robb JC et al. Double-blind comparison of addition of a second mood stabilizer versus an antidepressant to an initial mood stabilizer for treatment of patients with bipolar depression. Am. J. Psychiatry157, 124–126 (2000).
  • McElroy SL, Keck PE Jr. Treatment guidelines for valproate in bipolar, schizoaffective disorders. Can. J. Psychiatry38, 62–66 (1993)
  • Winsberg ME, DeGolia SG, Strong CM et al. Divalproex therapy in medication-naive and mood-stabilizer-naive bipolar II depression. J. Affect. Disorders67, 207–212 (2001).
  • Calabrese JR, Bowden CL, Sachs GS et al. A double-blind placebo-controlled study of lamotrigine monotherapy in out-patients with bipolar I depression. Lamictal 602 Study Group. J. Clin. Psychiatry60, 79–88 (1999).
  • Frye MA, Ketter TA, Kimbrell TA et al. A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders. J. Clin. Psychopharmacol.20, 607–614 (2000).
  • Goldsmith DR, Wagstaff AJ, Ibbotson T, Perry CM. Lamotrigine: a review of its use in bipolar disorder. Drugs63, 2029–2050 (2003).
  • Tohen M, Vieta E, Calabrese J et al. Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch. Gen. Psych.60, 1079–1088 (2003).
  • Macfadden W, Calabrese J. Presented at 24th CINP Meeting, June 20–24, Paris, France (2004).
  • Mitchell PB, Wilhelm K, Parker G, Austin M-P, Rutgers P, Malhi GS. The clinical features of bipolar depression: a comparison with matched major depressive disorder patients. J. Clin. Psychiatry62, 212–216 (2001).
  • Singh J, Zarate CA, Krystal AD. Case report: successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine. Psychopharmacology173, 227–228 (2004).
  • Hahn C-G, Gyulai L, Baldassano CF, Lenox RH. The current understanding of lamotrigine as a mood stabilizer. J. Clin. Psychiatry65, 791–804 (2004).
  • Burgess S, Geddes J, Hawton K et al. Lithium for maintenance treatment of mood disorders (Cochrane Review). The Cochrane Library 4 Update Software, Oxford, UK (2001).
  • Bowden CL, Brugger AM, Swann AC et al. Efficacy of divalproex vs. lithium and placebo in the treatment of mania. JAMA27, 918–924 (1994).
  • Prien RF, Klett CJ, Caffey EM Jr. Lithium carbonate and imipramine in prevention of affective episodes; a comparison in recurrent affective illness. Arch. Gen. Psych.29, 420–425 (1973).
  • Kane JM, Quitkin FM, Rifkin A et al. A. Lithium carbonate and Imipramine in the prophylaxis of unipolar and bipolar II illness: a prospective, placebo-controlled comparison. Arch. Gen. Psych.39, 1065–1069 (1982).
  • Geddes JR, Burgess S, Hawton K, Jamison K, Goodwin GM. Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials. Am. J. Psychiatry161, 217–222 (2004).
  • Macritchie KAN, Geddes JR, Scott J et al. Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder (Cochrane Review). The Cochrane Library 4 Update Software, Oxford, UK (2001).
  • Bowden CL, Calabrese JR, McElroy SL et al. A randomized, placebo-controlled12-month trial of divalproex and lithium in treatment of out-patients with bipolar I disorder. Arch. Gen. Psych.57, 481–489 (2000).
  • Dardennes R, Even C, Bange F et al. Comparison of carbamazepine and lithium in the prophylaxis of bipolar disorders: a meta-analysis. Br. J. Psychiatry166, 378–381 (1995).
  • Davis JM, Janicak PG, Hogan DM. Mood stabilizers in the prevention of recurrent affective disorders: a meta-analysis. Acta Psychiatr. Scand.100, 406–417 (1999).
  • Baldessarini RJ. Effects of lithium treatment and its discontinuation on suicidal behaviour in bipolar manic depressive disorders. J. Clin. Psychiatry60, 77–84 (1999).
  • Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D. Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA290, 1467–1473 (2002).
  • Okuma T, Inanaga K, Otsuki S et al. A preliminary double-blind study on the efficacy of carbamazepine in prophylaxis of manic-depressive illness. Psychopharmacology73, 95–95 (1981).
  • Denicoff KD, Smith-Jackson EE, Disney ER et al. Comparative prophylactic efficacy of lithium, carbamazepine, and the combination in bipolar disorder. J. Clin. Psychiatry58, 470–478 (1997).
  • Greil W, Ludwig-Mayerhofer W, Erazo N et al. Lithium vs. carbamazepine in the maintenance treatment of bipolar disorders – a randomized study. J. Affect. Disorders43, 151–161 (1997).
  • Gyulai L, Bowden CL, McElroy SL et al. Maintenance efficacy of divalproex in the prevention of bipolar depression. Neuropsychopharmacology28, 1374–1382 (2003).
  • Bowden CL, Calabrese JR, Sachs G et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch. Gen. Psych.60, 392–400 (2003).
  • Calabrese JR, Bowden CL, Sachs G. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar disorder. J. Clin. Psychiatry64, 1013–1024 (2003).
  • Goodwin GM, Bowden CL, Calabrese JR et al. A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder. J. Clin. Psychiatry65, 432–441 (2004).
  • Tohen M, Ketter TA, Zarate CA et al. Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. Am. J. Psychiatry160, 1263–1271 (2003)
  • Tohen M, Chengappa KN, Suppes T et al. Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser vs. mood stabiliser alone. Br. J. Psychiatry184, 337–345 (2004).
  • Tohen M, Marneros A, Bowden C et al. Olanzapine versus lithium in relapse prevention in bipolar disorder: a randomized double-blind controlled 12-month clinical trial. Presented at Stanley Foundation Bipolar Network Meeting, September, Freiberg, Germany (2002).
  • Lam DH, Watkins ER, Hayward P. A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year. Arch. Gen. Psych.60, 145–152 (2003).
  • Perry A, Tarrier N, Morriss R et al. Randomized controlled trial of efficacy of teaching patients with bipolar disorder to identify early symptoms of relapse and obtain treatment. Br. Med. J.318, 149–153 (1999).
  • Miklowitz DJ, George EL, Richards, JA et al. A randomized study of family-focused psychoeducation and pharmacotherapy in the out-patient management of bipolar disorder. Arch. Gen. Psych.60, 904–912 (2003).
  • Colom F, Vieta E, Martinez-Aran A et al. A randomized trial on the efficacy of group psychoeducation prophylaxis of recurrences in bipolar patients whose disease is in remission. Arch. Gen. Psych.60, 402–407 (2003).
  • Frank E, Kupfer DJ, Ihlers CL et al. Interpersonal and social rhythm therapy for bipolar disorder. Behav. Ther.17, 143–149 (1994).
  • Sachs GS, Printz DJ, Kahn DA, Carpenter D, Docherty JP. The Expert Consensus Guideline Series: Medication Treatment Of Bipolar Disorder 2000. McGraw-Hill, NY, USA, 1–104 (2000).
  • Boerlin HL, Gitlin MJ, Zoellner LA et al. Bipolar depression and antidepressant-induced mania: a naturalistic study. J. Clin. Psychiatry59, 374–381 (1998).
  • Bottlender R, Rudolf D, Straub A. Mood-stabilizers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar 1 depressed patients. J. Affect. Disorders63, 79–83 (2001).
  • Vieta E, Martinez-Aran A, Goikolea JM et al. A randomized trial comparing paroxetine and venlafaxine in the treatment of bipolar depressed patients taking mood stabilizers. J. Clin. Psychiatry63, 508–512 (2002).
  • UK ECT Review Group. Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. Lancet361, 799–808 (2003).
  • Vieta E, Colom F. Psychological interventions in bipolar disorder: from wishing thinking to an evidence-based approach. Acta Psych. Scandinav.11(Suppl. 422), 34–38 (2004).

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