321
Views
5
CrossRef citations to date
0
Altmetric
Review

Vaccines against ‘the other’ Ebolavirus species

&
Pages 1093-1100 | Received 13 Jan 2016, Accepted 22 Mar 2016, Published online: 12 Apr 2016

References

  • Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team. Bull World Health Organ. 1978;56(2):247–270.
  • Ebola haemorrhagic fever in Zaire, 1976. Bull World Health Organ. 1978;56(2):271–293.
  • Ellis DS, Bowen ET, Simpson DI, et al. Ebola virus: a comparison, at ultrastructural level, of the behaviour of the Sudan and Zaire strains in monkeys. Br J Exp Pathol. 1978 Dec;59(6):584–593.
  • Lupton HW, Lambert RD, Bumgardner DL, et al. Inactivated vaccine for Ebola virus efficacious in guineapig model. Lancet. 1980 [Dec 13];2(8207):1294–1295.
  • Geisbert TW, Pushko P, Anderson K, et al. Evaluation in nonhuman primates of vaccines against Ebola virus. Emerg Infect Dis. 2002 May;8(5):503–507.
  • Sullivan NJ, Sanchez A, Rollin PE, et al. Development of a preventive vaccine for Ebola virus infection in primates. Nature. 2000 [Nov 30];408(6812):605–609.
  • Geisbert TW, Strong JE, Feldmann H. Considerations in the use of nonhuman primate models of ebola virus and marburg virus infection. J Infect Dis. 2015 [Oct 1];212 Suppl 2:S91–7.
  • Jansen HJ, Breeveld FJ, Stijnis C, et al. Biological warfare, bioterrorism, and biocrime. Clin Microbiol Infec. 2014 Jun;20(6):488–496.
  • Kuhn JH, Dodd LE, Wahl-Jensen V, et al. Evaluation of perceived threat differences posed by filovirus variants. Biosecur Bioterror. 2011 Dec;9(4):361–371.
  • De La Vega MA, Stein D, Kobinger GP. Ebolavirus evolution: past and present. PLoS Pathog. 2015 Nov;11(11):e1005221.
  • Anthony SM, Bradfute SB. Filoviruses: one of these things is (not) like the other. Viruses. 2015 Oct;7(10):5172–5190.
  • Baize S, Pannetier D, Oestereich L, et al. Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med. 2014 [Oct 9];371(15):1418–1425.
  • Alexander KA, Sanderson CE, Marathe M, et al. What factors might have led to the emergence of Ebola in West Africa? PLoS Negl Trop Dis. 2015 Jun;9(6):e0003652.
  • Towner JS, Sealy TK, Khristova ML, et al. Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog. 2008 Nov;4(11):e1000212.
  • Mire CE, Geisbert JB, Versteeg KM, et al. A single-vector, single-injection trivalent filovirus vaccine: proof of concept study in outbred Guinea Pigs. J Infect Dis. 2015 [Oct 1];212 Suppl 2:S384–8.
  • Rougeron V, Feldmann H, Grard G, et al. Ebola and Marburg haemorrhagic fever. J Clin Virol. 2015 Mar;64:111–119.
  • De La Vega M-A, Wong G, Kobinger GP, et al. The multiple roles of sGP in Ebola pathogenesis. Viral Immunol. 2015 Feb;28(1):3–9.
  • Wilson JA, Hevey M, Bakken R, et al. Epitopes involved in antibody-mediated protection from Ebola virus. Science. 2000 [Mar 3];287(5458):1664–1666.
  • Althaus CL, Low N, Musa EO, et al. Ebola virus disease outbreak in Nigeria: transmission dynamics and rapid control. Epidemics. 2015 Jun;11:80–84.
  • Cenciarelli O, Gabbarini V, Pietropaoli S, et al. Viral bioterrorism: learning the lesson of Ebola virus in West Africa 2013-2015. Virus Res. 2015 [Dec 2];210:318–326.
  • Wong G, Kobinger GP. Backs against the wall: novel and existing strategies used during the 2014-2015 Ebola virus outbreak. Clin Microbiol Rev. 2015 Jul;28(3):593–601.
  • Sridhar S. Clinical development of Ebola vaccines. Ther Advances Vaccines. 2015 Sep;3(5–6):125–138.
  • Tapia MD, Sow SO, Lyke KE, et al. Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2016 Jan;16(1):31–42.
  • De Santis O, Audran R, Pothin E, et al. Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study. Lancet Infect Dis. 2016 Mar;16(3):311–320.
  • Kennedy SB, Neaton JD, Lane HC, et al. Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: design, procedures, and challenges. Clin Trials. 2016 Feb;13(1):49–56.
  • Jones SM, Feldmann H, Stroher U, et al. Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses. Nat Med. 2005;11(7):786–790.
  • Garbutt M, Liebscher R, Wahl-Jensen V, et al. Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses. J Virol. 2004;78(10):5458–5465.
  • Henao-Restrepo AM, Longini IM, Egger M, et al. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet. 2015 [Aug 29];386(9996):857–866.
  • Mire CE, Miller AD, Carville A, et al. Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates. PLoS Negl Trop Dis. 2012;6(3):e1567.
  • Geisbert TW, Daddario-Dicaprio KM, Lewis MG, et al. Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates. PLoS Pathog. 2008 Nov;4(11):e1000225.
  • Wong G, Richardson JS, Pillet S, et al. Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates. Sci Transl Med. 2012 [Oct 31];4(158):158ra46.
  • Stanley DA, Honko AN, Asiedu C, et al. Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge. Nat Med. 2014;20(10):1126–1129.
  • Shoemaker T, MacNeil A, Balinandi S, et al. Reemerging Sudan Ebola virus disease in Uganda, 2011. Emerg Infect Dis. 2012 Sep;18(9):1480–1483.
  • Martin JE, Sullivan NJ, Enama ME, et al. A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial. Clin Vaccine Immunol. 2006 Nov;13(11):1267–1277.
  • Sarwar UN, Costner P, Enama ME, et al. Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial. J Infect Dis. 2015 [Feb 15];211(4):549–557.
  • Kibuuka H, Berkowitz NM, Millard M, et al. Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial. Lancet. 2015 [Apr 18];385(9977):1545–1554.
  • Ledgerwood JE, Costner P, Desai N, et al. A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults. Vaccine. 2010 [Dec 16];29(2):304–313.
  • Ledgerwood JE, DeZure AD, Stanley DA, et al. Chimpanzee adenovirus vector Ebola vaccine - preliminary report. N Engl J Med. 2014 [Nov 26].
  • Warfield KL, Dye JM, Wells JB, et al. Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles. Plos One. 2015;10(3):e0118881.
  • Zahn R, Gillisen G, Roos A, et al. Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species. Plos One. 2012;7(12):e44115.
  • Wang D, Raja NU, Trubey CM, et al. Development of a cAdVax-based bivalent ebola virus vaccine that induces immune responses against both the Sudan and Zaire species of Ebola virus. J Virol. 2006 Mar;80(6):2738–2746.
  • Pratt WD, Wang D, Nichols DK, et al. Protection of nonhuman primates against two species of Ebola virus infection with a single complex adenovirus vector. Clinical Vaccine Immunology: CVI. 2010 Apr;17(4):572–581.
  • Richardson JS, Pillet S, Bello AJ, et al. Airway delivery of an adenovirus-based Ebola virus vaccine bypasses existing immunity to homologous adenovirus in nonhuman primates. J Virol. 2013 Apr;87(7):3668–3677.
  • Willet M, Kurup D, Papaneri A, et al. Preclinical development of inactivated rabies virus-based polyvalent vaccine against rabies and filoviruses. J Infect Dis. 2015 [Oct 1];212 Suppl 2:S414–24.
  • Herbert AS, Kuehne AI, Barth JF, et al. Venezuelan equine encephalitis virus replicon particle vaccine protects nonhuman primates from intramuscular and aerosol challenge with ebolavirus. J Virol. 2013 May;87(9):4952–4964.
  • Geisbert TW, Geisbert JB, Leung A, et al. Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus. J Virol. 2009;83(14):7296–7304.
  • Wong G, He S, Wei H, et al. Development and characterization of a Guinea pig-adapted Sudan virus. J Virol. 2015;90(1):392–399.
  • Geisbert TW, Daddario-DiCaprio KM, Williams KJ, et al. Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates. J Virol. 2008 Jun;82(11):5664–5668.
  • Wamala JF, Lukwago L, Malimbo M, et al. Ebola hemorrhagic fever associated with novel virus strain, Uganda, 2007-2008. Emerg Infect Dis. 2010 Jul;16(7):1087–1092.
  • Kratz T, Roddy P, Tshomba Oloma A, et al. Ebola virus disease outbreak in Isiro, democratic republic of the Congo, 2012: signs and symptoms, management and outcomes. Plos One. 2015;10(6):e0129333.
  • Roddy P, Howard N, Van Kerkhove MD, et al. Clinical manifestations and case management of Ebola haemorrhagic fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008. Plos One. 2012;7(12):e52986.
  • Falzarano D, Feldmann F, Grolla A, et al. Single immunization with a monovalent vesicular stomatitis virus-based vaccine protects nonhuman primates against heterologous challenge with Bundibugyo ebolavirus. J Infect Dis. 2011 Nov;204 Suppl 3:S1082–9.
  • Hensley LE, Mulangu S, Asiedu C, et al. Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species. PLoS Pathog. 2010 May;6(5):e1000904.
  • Mire CE, Geisbert JB, Marzi A, et al. Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus. PLoS Negl Trop Dis. 2013;7(12):e2600.
  • Jayme SI, Field HE, De Jong C, et al. Molecular evidence of Ebola Reston virus infection in Philippine bats. Virol J. 2015;12:107.
  • Sayama Y, Demetria C, Saito M, et al. A seroepidemiologic study of Reston ebolavirus in swine in the Philippines. BMC Vet Res. 2012;8:82.
  • Taniguchi S, Sayama Y, Nagata N, et al. Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines. BMC Vet Res. 2012;8:189.
  • Jahrling PB, Geisbert TW, Jaax NK, et al. Experimental infection of cynomolgus macaques with Ebola-Reston filoviruses from the 1989-1990 U.S. epizootic. Archives of Virology Supplementum. 1996;11:115–134.
  • Miranda ME, Ksiazek TG, Retuya TJ, et al. Epidemiology of Ebola (subtype Reston) virus in the Philippines, 1996. Journal of Infectious Diseases. 1999;179 Suppl 1:S115–9.
  • Barrette RW, Metwally SA, Rowland JM, et al. Discovery of swine as a host for the Reston ebolavirus. Science. 2009 [Jul 10];325(5937):204–206.
  • Marsh GA, Haining J, Robinson R, et al. Ebola Reston virus infection of pigs: clinical significance and transmission potential. J Infect Dis. 2011;204 Suppl 3:S804–9.
  • Le Guenno B, Formenty P, Wyers M, et al. Isolation and partial characterisation of a new strain of Ebola virus. Lancet. 1995 [May 20];345(8960):1271–1274.
  • Leroy EM, Telfer P, Kumulungui B, et al. A serological survey of Ebola virus infection in central African nonhuman primates. J Infect Dis. 2004 [Dec 1];190(11):1895–1899.
  • Formenty P, Boesch C, Wyers M, et al. Ebola virus outbreak among wild chimpanzees living in a rain forest of Cote d’Ivoire. J Infect Dis. 1999;179 Suppl 1:S120–6.
  • Lai L, Davey R, Beck A, et al. Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick. Jama. 2015 [Mar 24-31];313(12):1249–1255.
  • Wong G, Audet J, Fernando L, et al. Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents. Vaccine. 2014 [Sep 29];32(43):5722–5729.
  • Mire CE, Geisbert JB, Agans KN, et al. Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates. Plos One. 2014;9(4):e94355.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.