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Review

Progress towards the use of Listeria monocytogenes as a live bacterial vaccine vector for the delivery of HIV antigens

Yvonne Paterson University of Pennsylvania, 323 Johnson Pavilion, 36th St. and Hamilton Walk, Philadelphia, PA 19104-6076. [email protected]
&
R Johnson Virginia State University, Department of Biology, P.O. Box 9064, Petersburg, VA 23806, USA. [email protected]
Pages S119-S134 | Published online: 09 Jan 2014

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  • ••Demonstrates that prior exposure to mutant strains of L. monocytogenes that lack certain immunodominant epitopes does not inhibit the development of a primary cu, response to these epitopes delivered by wild-type L. monocytogenes These results suggest that pre-existing vector immunity will not inhibit the use of L. monocytogenes as a vaccine vector.

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