New recombinant vaccines based on the use of prokaryotic antigen-display systems

References

• Boyer JD, Cohen AD, Vogt S et al. Vaccination of seronegative volunteers with a human immunodeficiency virus Type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of B-chemokines. .1. Infect. Dis. 181, 476–483 (2000).
   Google Scholar
• Baba TW, Liska V, Khimani AH eta]. Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nature Med. 5, 194–203 (1999).
   Google Scholar
• Robinson HL. New hope for an AIDS vaccine. Nature Rev. Immunol. 2, 239–250 (2002).
   PubMed Web of Science ®Google Scholar
• Belshe RB, Stevens C, Gorse GJ et al. Safety and immunogenicity of a canarypox-vectored human immunodeficiency virus Type 1 vaccine with or without gp120: a Phase II study in higher and lower-risk volunteers. .1. Infect. Dis. 183, 1343–1352 (2001).
   Google Scholar
• Cooney EL, Collier AC, Greenberg PD et al. Safety and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein. Lancet337, 567–572 (1991).
   PubMed Web of Science ®Google Scholar
• Barnett SW, Rajasekar S, Legg H eta]. Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit. Vaccine 15, 869–873 (1997).
   Google Scholar
• Robinson HL, Montefiori DC, Johnson RP et al. Neutralizing antibody-independent containment of immunodeficiency virus challenge by DNA priming and recombinant poxvirus booster immunizations. Nature Med. 5, 526–534 (1999).
   PubMed Web of Science ®Google Scholar
• Amara RR, Villinger F, Altman JD et al Control of mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Sdence292, 69–74 (2001).
   Google Scholar
• BarouchDH, Santra S, Schmitz JE et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 290, 486–492 (2000).
   Google Scholar
• Wee EG, Patel S, McMichael AJ, Hanke T. A DNA/MVA-based candidate human immunodeficiency virus vaccine for Kenia induces multispecific T-cell response in rhesus macaques. .1. Gen. Virol. 83, 75–80 (2002).
   Google Scholar
• Doria-Rose NA, Ohlen AC, Polacino P eta]. Multigene DNA priming-boosting vaccines protect macaques from acute CD4-T-cell depletion after Simian-human immunodeficiency virus 5HIV89.6P mucosal challenge. .1. Vim]. 77, 11563–11577 (2003).
   Google Scholar
• •Role of different types of prime—boosting for protection in nonhuman primates vaccine SHIV challenge models.
   Google Scholar
• Graham BS. Clinical trials of HIV vaccines. Ann. Rev. Med. 53, 207–221 (2002).
   PubMedGoogle Scholar
• Folgori A, Tall R, Meola A eta]. A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO I 13(9), 2236–2243 (1994).
   PubMed Web of Science ®Google Scholar
• Irving MB, Pan O, Scott JK. Random- peptide libraries and antigen fragment libraries for epitope mapping and the development of vaccines and diagnostics. Carr. Opin. Chem. Biol. 5(39), 314–324 (2001).
   Google Scholar
• Bastien N, Trudel M, Simard C. Protective immune responses induced by the immunization of mice with a recombinant bacteriophage displaying an epitope of the human respiratory syncytial virus. Virology 234 (1), 118–122 (1997).
   PubMed Web of Science ®Google Scholar
• Chen X, Scala G, Quinto I eta]. Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes. Nature Med. 7(11), 1225–1231 (2001).
   Google Scholar
• Clark JR, March JB. Bacteriophage- mediated nucleic acid immunization. FEMS ImmunoL Med. MicrobioL 40 (1), 21–26 (2004).
   Web of Science ®Google Scholar
• Benhar I. Biotechnological applications of phages and cell display. BiotechnoL Adv 19(1), 1–33 (2001).
   Google Scholar
• Kieber-Emmons T, Luo P, Qiu J eta]. Vaccination with carbohydrate peptide mimotopes promotes antitumor responses. Nature BiotechnoL17 (7), 660–665 (1999).
   PubMed Web of Science ®Google Scholar
• Wang LF, Yu M. Epitope identification and discovery using phage display libraries: apllications in vaccine development and diagnostics. Carr. Drug Targets 5(1), 1–15 (2004).
   PubMed Web of Science ®Google Scholar
• Manoutcharian K, Diaz-Orea A, Gevorkian G et al. Recombinant bacteriophage-based multiepitope vaccine against Taenia solium pig cysticercosis. Vet. Irnmunol. Irnmunopathol. 99,11–24 (2004).
   PubMed Web of Science ®Google Scholar
• •Protectve capability of M13 phage vaccine against pig cysticercosis.
   Google Scholar
• Grenwood J, Willis AE, Perham RN. Multiple display of foreign peptides on a filamentous bacteriophage: peptides from P/asrnodium fa/ciparum sporozoite protein as antigen.' MoL Biol. 220,821–827 (1991).
   Google Scholar
• Iannolo G, Minnenkova O, Petruzzelli R, Cesareni G. Modifying filamentous phage capsid: limits in the size of the major capsid protein. J Mol. Biol. 248,835–844 (1995).
   PubMed Web of Science ®Google Scholar
• Malik P, Terry TD, Gowda LR et al. Role of capsid structure and membrane protein processing in determining the size and copy number of peptides displayed on the major coat protein of filamentous bacteriophage. J MoL Biol. 260,9–21 (1996).
   PubMed Web of Science ®Google Scholar
• •Description of new vectors obtained by modifying the genome of the filamentous bacteriophage fd for the purpose of displaying peptides on the surface of the virion.
   Google Scholar
• Cano A, Viveros M, Acero G et al. Antigenic properties of phage-displayed peptides comprising disulfide-bonded loop of the immunodominant region of HIV-1 gp41. I17717711fla Lett. 95,207-212 (2004).
   Google Scholar
• Malik P, Perham RN. New vectors for peptide display on the surface of filamentous bacteriophage. Gene 171, 49–51 (1996).
   Google Scholar
• De Berardinis P, D'apice L, Prisco A et al. Recognition of HIV-derived B- and T-cell epitopes displayed on filamentous phages. Vaccine17,1434–1441 (1999).
   Google Scholar
• De Berardinis P, Sartorius R, Fanutti C et al. Phage display of peptides epitopes from HIV-1 elicits strong cytolytic responses. Nature Biotech. 18,873–876 (2000).
   PubMed Web of Science ®Google Scholar
• ••Hybrid bacteriophages double displayinghelper and cytolytic peptides are able to evoke an antigen-specific cytotoxic T-lymphocyte responses both in vitro and in vivo.
   Google Scholar
• Minenkova OO, Ilychev AA, Kishenko GP, Petrenko VA. Design of specific immunogens using filamentous bacteriophage as the carrier. Gene 128, 85–88 (1993).
   PubMed Web of Science ®Google Scholar
• Perham RN, Terry TD, Willis AE et al. Engineering a peptide epitope display system on filamentous bacteriophage. FEMS MicrobioL Rev.17, 25–31 (1995).
   Google Scholar
• Jelinek R, Terry TD, Gesell JJ et al. NMR structure of the principal neutralizing determinant of HIV-1 displayed in filamentous bacteriophage coat protein. MoL Biol. 266,649–655 (1997).
   Google Scholar
• •Structure determination of peptides displayed on the surface of filamentous bacteriophage virions.
   Google Scholar
• Gaubin M, Fanutti C, Mishal Z et al. Processing by APC of filamentous phage displaying antigenic epitopes targets to both HLA class I and class II peptide-loading compartments. DNA Cell Biol. 22(1), 11–18 (2003).
   Google Scholar
• •Virions are taken up by antigen-presenting cells to yield peptides that reach both the major histocompatibility complex class II compartment and the endoplasmic reticulum.
   Google Scholar
• Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol. 8(2), 84–87 (1998).
   PubMed Web of Science ®Google Scholar
• Trepel M, Arap W, Pasqualini R. Modulation of the immune response by systemic targeting of antigens to lymph nodes. Cancer Res. 61,8110–8112 (2001).
   Google Scholar
• Domingo, GJ, Orru S, Perham RN. Multiple display of peptides and proteins on a macromolecular scaffold derived from a multienzyme complex. J MoL Biol. 305, 259–267 (2001).
   Google Scholar
• ••Simultaneous display of antigen epitopeson the icosahedral scaffold formed by the dihydrolipoyl acetyltransferase component (E2) of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus.
   Google Scholar
• Domingo GJ, Caivano A, Sartorius R et al. Induction of specific T-helper and cytolytic responses to epitopes displayed on a virus-like protein scaffold derived from the pyruvate dehydrogenase multienzyme complex. Vaccine 21, 1502–1509 (2003).
   Google Scholar
• •Priming of antigen-specific cytotoxic T-cell response by peptides displayed on the E2 icosahedral lattice.
   Google Scholar
• Henderson CE, Perham RN, Finch JT. Structure and symmetry of B. stearotherrnophiluspyruvate dehydrogenase multienzyme complex and implications for eucaryote evolution. Cell 17, 85–93 (1979).
   Google Scholar
• Perham RN. Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions. Ann. Rev. Biochem. 69, 961–1004 (2000).
   PubMedGoogle Scholar
• Allen MD, Perham RN. The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearotherrnphilus. Expression, purification and reversible denaturation. FEBS Lett. 413,339–343 (1997).
   Google Scholar
• Lessard IA, Domingo GJ, Borges A, Perham RN. Expression of genes encoding the E2 and E3 components of the Bacillus stearotherrnophilus pyruvate dehydrogenase complex and the stoichiometry of subunit interaction in assembly in vitro. Eur. J Biochern. 258, 491–501 (1998).
   Google Scholar
• Dale CJ, Liu XS, De Rose R al. Chimeric human papilloma virus-simian/human immunodeficiency virus-like-particle vaccines: immunogenicity and protective efficacy in macaques. Virology301, 176–187 (2002).
   PubMed Web of Science ®Google Scholar
• Benson EM, Clarkson J, Law M et al. Therapeutic vaccination with p24-VLP and Zidovudine augments HIV-specific cytotoxic T-lymphocyte activity in asymptomatic HIV-infected individuals. AIDS research & Human Retro virus 15, 105–113 (1999).
   PubMed Web of Science ®Google Scholar
• O'Hagan DT, Ott GS, Van Nest G. Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. Mol. Med. Today 3,69–75 (1977).
   Google Scholar
• Mooij P, Nieuwenhuis G, Knoop CJ et al. Qualitative T-helper responses to multiple viral antigens correlate with vaccine-induced immunity to simian/human immunodeficiency virus infection. J. Virol. 78,3333–3342 (2004).
   PubMed Web of Science ®Google Scholar