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Expert Review of Vaccines Volume 4, 2005 - Issue 5
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Review

Vaccination of the immunocompromised child

Thomas H Casswall Karolinska University Hospital, Paediatric Gastroenterology, Hepatology and Nutrition, Children’s Hospital, Karolinska, University Hospital, Sweden. [email protected]
&
Björn Fischler Karolinska University Hospital, Paediatric Gastroenterology, Hepatology and Nutrition, Children’s Hospital, Karolinska, University Hospital, Sweden. [email protected]
Pages 725-738 | Published online: 09 Jan 2014

References

  • Groth CG, Berglin E. 2004 – a year of jubilee for solid organ transplantation. Lakartidningen 101, 4219–4223 (2004).
  • Zinkernagel RM. On natural and artificial vaccinations. Ann. Rev. Immunol. 21, 515–546 (2003).
  • Plotkin SA. Immunologic correlates of protection induced by vaccination. Pediatr. Infect. Dis. J. 20(1), 63–75 (2001).
  • Permar SR, Klumpp SA, Mansfield KG et al. Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys. J. Infect. Dis. 190(5), 998–1005 (2004).
  • Giudice GD. Vaccination strategies. An overview. Vaccine 21, (Suppl. 2), S83–S88 (2003).
  • Beverley PC. Immunology of vaccination. Br. Med. Bull. 62, 15–28 (2002).
  • McVernon J, Mitchison NA, Moxon ER. T helper cells and efficacy of Haemophilus influenzae type b conjugate vaccination. Lancet Infect. Dis. 4(1), 40–43 (2004).
  • Eskola J. Immunogenicity of pneumococcal conjugate vaccines. Pediatr. Infect. Dis. J. 19(4), 388–393 (2000).
  • Farrell RJ, Kelleher D. Glucocorticoid resistance in inflammatory bowel disease. J. Endocrinol. 178(3), 339–346 (2003).
  • Stark K, Gunther M, Schonfeld C, Tullius SG, Bienzle U. Immunisations in solid-organ transplant recipients. Lancet 359(9310), 957–965 (2002).
  • Cara CJ, Pena AS, Sans M et al. Reviewing the mechanism of action of thiopurine drugs: Towards a new paradigm in clinical practice. Med. Sci. Monit. 10(11), RA247–254 (2004).
  • Kapturczak MH, Meier-Kriesche HU, Kaplan B. Pharmacology of calcineurin antagonists. Transplant. Proc. 36(Suppl. 2), 25S–32S (2004).
  • Kelly PA, Gruber SA, Behbod F, Kahan BD. Sirolimus, a new, potent immunosuppressive agent. Pharmacotherapy 17(6), 1148–56 (1997).
  • Rowinsky EK. Targeting the molecular target of rapamycin (mTOR). Curr. Opin. Oncol. 16(6), 564–575 (2004).
  • Lopez MJ, Thomas S. Immunization of children after solid organ transplantation. Pediatr. Clin. North Am. 50(6), 1435–1449 (2003).
  • Burroughs M, Moscona A. Immunization of pediatric solid organ transplant candidates and recipients. Clin. Infect. Dis. 30, 857–869 (2000).
  • Duchini A, Hendry RM, Redfield DC, Pockros PJ. Influenza infection in patients before and after liver transplantation. Liver Transpl. 6(5), 531–542 (2000).
  • Vilchez RA, McCurry K, Dauber J et al. Influenza virus infection in adult solid organ transplant recipients. Am. J. Transplant. 2(3), 287–91 (2002).
  • Duchini A, Goss JA, Karpen S, Pockros PJ. Vaccinations for adult solid-organ transplant recipients: current recommendations and protocols. Clin. Microbiol. Rev. 16(3), 357–364 (2003).
  • Belshe R, Lee MS, Walker RE, Stoddard J, Mendelman PM. Safety, immunogenicity and efficacy of intranasal, live attenuated influenza vaccine. Expert Rev. Vaccines 3(6), 643–654 (2004).
  • Gennery AR, Cant AJ, Baldwin CI, Calvert JE. Characterization of the impaired antipneumococcal polysacharide antibody production in immunosuppressed pediatric patients following cardiac transplantation. J. Clin. Immunol. 21(1), 43–50 (2001).
  • Thall TV, Rosh JR, Schwersenz AH et al. Primary immunization status in infants referred for liver transplantation. Transplant. Proc. 26(1), 191 (1994).
  • Nithichaiyo C, Chongsrisawat V, Hutagalung Y, Bock HL, Poovorawa Y. Immunogenicity and adverse effects of live attenuated varicella vaccine (Oka-strain) in children with chronic liver disease. Asian Pac. J. Allergy Immunol. 19(2), 101–105 (2001).
  • Greenbaum E, Nir-Paz R, Linton DM, Ben-Hur T, Meirovitz A, Zakay-Rones Z. Severe influenza infection in a chronic hepatitis C carrier: failure of protective serum HI antibodies after IM vaccination. J. Clin. Virol. 29(1), 23–26 (2004).
  • Mack DR, Chartrand SA, Ruby EI, Antonson DL, Shaw BW Jr, Heffron TG. Influenza vaccination following liver transplantation in children. Liver Transpl. Surg. 2(6), 431–437 (1996).
  • Kano H, Mizuta K, Sakakihara Y et al. Efficacy and safety of immunization for pre- and post-liver transplant children. Transplantation 74(4), 543–550 (2002).
  • Rand EB, McCarthy CA, Whitington PF. Measles vaccination after orthotopic liver transplantation. J. Pediatr. 123(1), 87–89 (1993).
  • Almasio PL, Amoroso P. HAV infection in chronic liver disease: a rationale for vaccination. Vaccine 21(19–20), 2238–2241 (2003).
  • Majda-Stanislawska E, Bednarek M, Kuydowicz J. Immunogenicity of inactivated hepatitis A vaccine in children with chronic liver disease. Pediatr. Infect. Dis. J. 23(6), 571–574 (2004).
  • Van Herck K, Van Damme P. Inactivated hepatitis A vaccine-induced antibodies: follow-up and estimates of long-term persistence. J. Med. Virol.63(1), 1–7 (2001).
  • Reiss G, Keeffe EB. Review article: hepatitis vaccination in patients with chronic liver disease. Aliment. Pharmacol. Ther. 19(7), 715–727 (2004).
  • Sokal EM, Ulla L, Otte JB. Hepatitis B vaccine response before and after transplantation in 55 extrahepatic biliary atresia children. Dig. Dis. Sci. 37(8), 1250–1252 (1992).
  • Ghio L, Pedrazzi C, Assael BM, Panuccio A, Foti M, Edefonti A. Immunity to diphtheria and tetanus in a young population on a dialysis regimen or with a renal transplant. J. Pediatr. 130(6), 987–989 (1997).
  • Huzly D, Neifer S, Reinke P et al. Routine immunizations in adult renal transplant recipients. Transplantation 63(6), 839–845 (1997).
  • Enke BU, Bokenkamp A, Offner G, Bartmann P, Brodehl J. Response to diphtheria and tetanus booster vaccination in pediatric renal transplant recipients. Transplantation 64(2), 237–241 (1997).
  • Furth SL, Hogg RJ, Tarver J, Moulton LH, Chan C, Fivush BA. Varicella vaccination in children with chronic renal failure. A report of the Southwest Pediatric Nephrology Study Group. Pediatr. Nephrol. 18(1), 33–38 (2003).
  • Laube GF, Berger C, Goetschel P, Leumann E, Neuhaus TJ. Immunization in children with chronic renal failure. Pediatr. Nephrol. 17(8), 638–642 (2002).
  • Fabrizi F, Martin P, Dixit V, Bunnapradist S, Dulai G. Meta-analysis: the effect of age on immunological response to hepatitis B vaccine in end stage renal disease. Aliment. Pharmacol. Ther. 20(10), 1053–1062 (2004).
  • Rangel MC, Coronado VG, Euler GL, Strikas RA. Vaccine recommendations for patients on chronic dialysis. The Advisory Committee on Immunization Practices and the American Academy of Pediatrics. Semin. Dial. 13(2), 101–107 (2000).
  • Neuhaus TJ. Immunization in children with chronic real failure: a practical approach. Pediatr. Nephrol. 19, 1334–1339 (2004).
  • Amber IJ, Gilbert EM, Schiffman G, Jacobson JA. Increased risk of pneumococcal infections in cardiac transplant recipients. Transplantation 49(1), 122–125 (1990).
  • Dengler TJ, Strnad N, Buhring I et al. Differential immune response to influenza and pneumococcal vaccination in immunosuppressed patients after heart transplantation. Transplantation 66(10), 1340–1347 (1998).
  • Blumberg EA, Brozena SC, Stutman P, Wood D, Phan HM, Musher DM. Immunogenicity of pneumococcal vaccine in heart transplant recipients. Clin. Infect. Dis. 32(2), 307–310 (2001).
  • Vilchez R, McCurry K, Dauber J et al. Influenza and parainfluenza respiratory viral infection requiring admission in adult lung transplant recipients. Transplantation 73(7), 1075–1078 (2002).
  • Kimball P, Verbeke S, Tolman D. Influenza vaccination among heart transplant recipients. Transplant. Proc. 33(1–2), 1785–1786 (2001).
  • Fraund S, Wagner D, Pethig K, Drescher J, Girgsdies OE, Haverich A. Influenza vaccination in heart transplant recipients. J. Heart Lung Transplant. 18(3), 220–225 (1999).
  • Centers for Disease Control and Prevention. Prevention and control of influenza. Recommendations of the advisory committee on immunization practices. Morb. Mortal. Wkly Rep. 49(RR-3), 1–38 (2000).
  • Avigan D, Pirofski LA, Lazarus HM. Vaccination against infectious disease following hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant. 7(3), 171–183 (2001).
  • Centers for Disease Control and Prevention. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Morb. Mortal. Wkly Rep. 49(RR-10), 1–128 (2000).
  • Ljungman P, Ward KN, Crooks BN et al. Respiratory virus infections after stem cell transplantation: a prospective study from the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant. 28(5), 479–484 (2001).
  • Moore SE, Goldblatt D, Bates CJ, Prentice AM. Impact of nutritional status on antibody responses to different vaccines in undernourished Gambian children. Acta. Paediatr. 92(2), 170–176 (2003).
  • Hugosson C, Harfi H. Disseminated BCG-osteomyelitis in congenital immunodeficiency. Pediatr. Radiol. 21(5), 384–385 (1991).
  • Perez EE, Bokszczanin A, McDonald-McGinn D, Zackai EH, Sullivan KE. Safety of live viral vaccines in patients with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). Pediatrics 112(4), e325–e-327 (2003).
  • Zuccotti GV, Cucchi C, Sala D, Giovannini M. Immunogenicity and safety of a virosomal influenza vaccine in HIV-infected children. Acta. Paediatr. 91(4), 486; author reply 487 (2002).
  • Zanetti AR, Amendola A, Besana S, Boschini A, Tanzi E. Safety and immunogenicity of influenza vaccination in individuals infected with HIV. Vaccine 20(Suppl. 5), B29–32 (2002).
  • Obaro SK, Pugatch D, Luzuriaga K. Immunogenicity and efficacy of childhood vaccines in HIV-1-infected children. Lancet 4, 510–518 (2004).
  • Davies K, Woo P. Immunization in rheumatic diseases of childhood: an audit of the clinical practice of British Paediatric Rheumatology Group members and a review of the evidence. Rheumatology 41(8), 937–941 (2002).
  • Kanakoudi-Tsakalidou F, Trachana M, Pratsidou-Gertsi P, Tsitsami E, Kyriazopoulou-Dalaina V. Influenza vaccination in children with chronic rheumatic diseases and long-term immunosuppressive therapy. Clin. Exp. Rheumatol. 19(5), 589–594 (2001).
  • Maillefert JF, Sibilia J, Toussirot E et al. Rheumatic disorders developed after hepatitis B vaccination. Rheumatology 38(10), 978–983 (1999).
  • Demicheli V, Rivetti A, Di Pietrantonj C, Clements CJ, Jefferson T. Hepatitis B vaccination and multiple sclerosis: evidence from a systematic review. J. Viral Hepat. 10(5), 343–344 (2003).
  • Kasapcopur O, Cullu F, Kamburoglu-Goksel A et al. Hepatitis B vaccination in children with juvenile idiopathic arthritis. Ann. Rheum. Dis. 63(9), 1128–1130 (2004).
  • Ioannou Y, Isenberg DA. Immunisation of patients with systemic lupus erythematosus: the current state of play. Lupus 8(7), 497–501 (1999).
  • Aron-Maor A, Shoenfeld Y. Vaccination and systemic lupus erythematosus: the bidirectional dilemmas. Lupus 10(3), 237–40 (2001).
  • Lindberg E, Lindquist B, Holmquist L, Hildebrand H. Inflammatory bowel disease in children and adolescents in Sweden, 1984–1995. J. Pediatr. Gastroenterol. Nutr. 30(3), 259–264 (2000).
  • Bremner AR, Griffiths DM, Beattie RM. Current therapy of ulcerative colitis in children. Expert Opin. Pharmacother. 5(1), 37–53 (2004).
  • Sands BE, Cuffari C, Katz J et al. Guidelines for immunizations in patients with inflammatory bowel disease. Inflamm. Bowel Dis. 10(5), 677–692 (2004).
  • Fairchok MP, Trementozzi DP, Carter PS, Regnery HL, Carter ER. Effect of prednisone on response to influenza virus vaccine in asthmatic children. Arch. Pediatr. Adolesc. Med. 152(12), 1191–1195 (1998).
  • Lahood N, Emerson SS, Kumar P, Sorensen RU. Antibody levels and response to pneumococcal vaccine in steroid-dependent asthma. Ann. Allergy 70(4), 289–94 (1993).
  • Zignol M, Peracchi M, Tridello G et al. Assessment of humoral immunity to poliomyelitis, tetanus, hepatitis B, measles, rubella, and mumps in children after chemotherapy. Cancer 101(3), 635–641 (2004).
  • Nilsson A, De Milito A, Engstrom P et al. Current chemotherapy protocols for childhood acute lymphoblastic leukemia induce loss of humoral immunity to viral vaccination antigens. Pediatrics 109(6), e91 (2002).
  • Feldman S, Lott L. Varicella in children with cancer: impact of antiviral therapy and prophylaxis. Pediatrics 80(4), 465–472 (1987).
  • Slifkin M, Doron S, Snydman DR. Viral prophylaxis in organ transplant patients. Drugs 64(24), 2763–2792 (2004).
  • Leung TF, Li CK, Hung EC et al. Immunogenicity of a two-dose regime of varicella vaccine in children with cancers. Eur. J. Haematol. 72(5), 353–357 (2004).
  • Chandra RK. Nutrition and immunology: from the clinic to cellular biology and back again. Proc. Nutr. Soc. 58(3), 681–683 (1999).
  • Bhaskaram P. Micronutrient malnutrition, infection, and immunity: an overview. Nutr. Rev. 60(5 Pt. 2), S40–S45 (2002).
  • Monova D, Belovezhdov N, Altunkova I, Monov S. Intravenous immunoglobulin G in the treatment of patients with chronic glomerulonephritis: clinical experience lasting 15 years. Nephron 90(3), 262–266 (2002).
  • Davison S. Acute hepatitis. In: Diseases of the Liver and Biliary System in Children. Kelly DA (Ed.). Blackwell Publishing, Birmingham, UK, 92–106 (2004).
  • Poddar U, Thapa BR, Prasad A, Sharma AK, Singh K. Natural history and risk factors in fulminant hepatic failure. Arch. Dis. Child. 87(1), 54–56 (2002).
  • Castagnola E, Fioredda F. Prevention of life-threatening infections due to encapsulated bacteria in children with hyposplenia or asplenia: a brief review of current recommendations for practical purposes. Eur. J. Haematol. 71(5), 319–326 (2003).
  • Ventura A, Nassimbeni G, Martelossi S, Bohm P, D’Agaro PL. Experience with γ−globulins per os in the therapy and prevention of infectious diarrhea. Pediatr. Med. Chir.15, 343–346 (1993).
  • Cant AJ, Davies G, Finn A, Foot A, Skinner R. Immunisation of the immunocompromised child. In: Best Practice Statement: Royal College of Paediatric and Child Health. Royal College of Paediatrics and Child Health, London, UK (2002).
  • Revised indications for the use of palivizumab and respiratory syncytial virus immune globulin intravenous for the prevention of respiratory syncytial virus infections. Pediatrics 112(6 Pt. 1), 1442–1446 (2003).
  • Boeckh M, Nichols WG. The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy. Blood 103(6), 2003–2008 (2004).
  • Triantos C, Samonakis D, Stigliano R, Thalheimer U, Patch D, Burroughs A. Liver transplantation and hepatitis C virus: systematic review of antiviral therapy. Transplantation 79(3), 261–268 (2005).
  • John TJ, Samuel R. Herd immunity and herd effect: new insights and definitions. Eur. J. Epidemiol. 16(7), 601–606 (2000).
  • Gans H, DeHovitz R, Forghani B, Beeler J, Maldonado Y, Arvin AM. Measles and mumps vaccination as a model to investigate the developing immune system: passive and active immunity during the first year of life. Vaccine 21(24), 3398–3405 (2003).
  • Cimaz R, Meregalli E, Biggioggero M et al. Alterations in the immune system of children from mothers treated with immunosuppressive agents during pregnancy. Toxicol. Lett. 149(1–3), 155–162 (2004).
  • Airo P, Antonioli CM, Motta M et al. The immune development in a child born to a cyclosporin A-treated woman with systemic lupus erythematosus/polymyositis. Lupus 11(7), 454–457 (2002).
  • Johny AA, Clark A, Price N, Carrington D, Oakhill A, Marks DI. The use of zanamivir to treat influenza A and B infection after allogeneic stem cell transplantation. Bone Marrow Transplant. 29(2), 113–115 (2002) .
  • Machado CM, Boas LS, Mendes AV et al. Use of Oseltamivir to control influenza complications after bone marrow transplantation. Bone Marrow Transplant. 34(2), 111–114 (2004).
  • Pirofski LA, Casadevall A. Use of licensed vaccines for active immunization of the immunocompromised host. Clin. Microbiol. Rev. 11(1), 1–26 (1998).
  • Sartori AM. A review of the varicella vaccine in immunocompromised individuals. Int. J. Infect. Dis. 8(5), 259–270 (2004).

Websites

  • Centers for Disease Control and Prevention www.cdc.gov/nip/publications (Accessed September 2005)
  • British Society for Rheumatology www.rheumatology.org.uk (Accessed September 2005)

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