Specific Lactobacillus species differentially activate Toll-like receptors and downstream signals in dendritic cells

References

• Ahrne S, Nobaek S, Jeppsson B, Adlerberth I, Wold AE, Molin G. The normal Lactobacillus flora of healthy human rectal and oral mucosa. J. Appl. Microbiol.85, 88–94 (1998).
   PubMed Web of Science ®Google Scholar
• Erickson KL, Hubbard NE. Probiotic immunomodulation in health and disease. J. Nutr.130, 403S–409S (2000).
   PubMed Web of Science ®Google Scholar
• Guarner F, Schaafsma GJ. Probiotics. Int. J. Food Microbiol.39, 237–238 (1998).
   PubMed Web of Science ®Google Scholar
• Johansson ML, Nobaek S, Berggren A et al. Molin G. Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats. Int. J. Food Microbiol.42, 29–38 (1998).
   PubMed Web of Science ®Google Scholar
• Klaenhammer TR. Probiotic bacteria: today and tomorrow. J. Nutr.130, 415S–416S (2000).
   PubMed Web of Science ®Google Scholar
• Kullen MJ, Klaenhammer TR. Genetic modification of intestinal lactobacilli and bifidobacteria. Curr. Issues Mol. Biol.2, 41–50 (2000).
   PubMedGoogle Scholar
• Bjorksten B, Naaber P, Sepp E, Mikelsaar M. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin. Exp. Allergy29, 342–346 (1999).
   PubMed Web of Science ®Google Scholar
• Holt PG, Jones CA. The development of the immune system during pregnancy and early life. Allergy55, 688–697 (2000).
   PubMed Web of Science ®Google Scholar
• Holt PG, Rudin A, Macaubas C et al. Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J. Allergy Clin. Immunol.105, 1117–1122 (2000).
   PubMed Web of Science ®Google Scholar
• Holt PG, Stumbles PA. Regulation of immunologic homeostasis in peripheral tissues by dendritic cells: the respiratory tract as a paradigm. J. Allergy Clin. Immunol.105, 421–429 (2000).
   PubMed Web of Science ®Google Scholar
• Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol.159, 1739–1745 (1997).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Olson S, Kalina WV et al. Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proc. Natl Acad. Sci. USA102, 2880–2885 (2005).
   PubMed Web of Science ®Google Scholar
• Steinman RM. Dendritic cells: understanding immunogenicity. Eur. J. Immunol.37(Suppl. 1) S53–S60 (2007).
   PubMed Web of Science ®Google Scholar
• Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature449, 419–426 (2007).
   PubMed Web of Science ®Google Scholar
• Kelsall BL, Strober W. Peyer‘s patch dendritic cells and the induction of mucosal immune responses. Res. Immunol.148, 490–498 (1997).
   PubMedGoogle Scholar
• Kelsall BL, Strober W. Dendritic cells of the gastrointestinal tract. Springer Semin. Immunopathol.18, 409–420 (1997).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Berard F, Essert G et al. Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J. Exp. Med.194, 1013–1020 (2001).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Ariizumi K, Sugamura K, Bergstresser PR, Takashima A. Expression of the common cytokine receptor γ chain by murine dendritic cells including epidermal Langerhans cells. Eur. J. Immunol.26, 156–160 (1996).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, McGuire MJ, Smith DJ, Gaspari AA, Bergstresser PR, Takashima A. Functional roles for granzymes in murine epidermal γ(δ) T-cell-mediated killing of tumor targets. J. Invest. Dermatol.107, 738–742 (1996).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Poltorak AN, Bergstressor PR, Beutler B, Takashima A. Dendritic cells produce macrophage inflammatory protein-1 γ, a new member of the CC chemokine family. J. Immunol.156, 3102–3106 (1996).
   PubMed Web of Science ®Google Scholar
• Reid G, Sanders ME, Gaskins HR et al. New scientific paradigms for probiotics and prebiotics. J. Clin. Gastroenterol.37, 105–118 (2003).
   PubMed Web of Science ®Google Scholar
• Grangette C, Muller-Alouf H, Goudercourt D, Geoffroy MC, Turneer M, Mercenier A. Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum. Infect. Immun.69, 1547–1553 (2001).
   PubMed Web of Science ®Google Scholar
• Mercenier A, Pavan S, Pot B. Probiotics as biotherapeutic agents: present knowledge and future prospects. Curr. Pharm. Des.9, 175–191 (2003).
   PubMed Web of Science ®Google Scholar
• Pavan S, Desreumaux P, Mercenier A. Use of mouse models to evaluate the persistence, safety, and immune modulation capacities of lactic acid bacteria. Clin. Diagn. Lab. Immunol.10, 696–701 (2003).
   PubMedGoogle Scholar
• Repa A, Grangette C, Daniel C et al. Mucosal co-application of lactic acid bacteria and allergen induces counter-regulatory immune responses in a murine model of birch pollen allergy. Vaccine22, 87–95 (2003).
   PubMed Web of Science ®Google Scholar
• Cross ML, Gill HS. Can immunoregulatory lactic acid bacteria be used as dietary supplements to limit allergies? Int. Arch. Allergy Immunol.125, 112–119 (2001).
   PubMed Web of Science ®Google Scholar
• Cross ML, Stevenson LM, Gill HS. Anti-allergy properties of fermented foods: an important immunoregulatory mechanism of lactic acid bacteria? Int. Immunopharmacol.1, 891–901 (2001).
   PubMed Web of Science ®Google Scholar
• Maassen CB, Boersma WJ, van Holten-Neelen C, Claassen E, Laman JD. Growth phase of orally administered Lactobacillus strains differentially affects IgG1/IgG2a ratio for soluble antigens: implications for vaccine development. Vaccine21, 2751–2757 (2003).
   PubMed Web of Science ®Google Scholar
• Kalliomaki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J. Allergy Clin. Immunol.107, 129–134 (2001).
   PubMed Web of Science ®Google Scholar
• Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet357, 1076–1079 (2001).
   PubMed Web of Science ®Google Scholar
• Pochard P, Gosset P, Grangette C et al. Lactic acid bacteria inhibit Th2 cytokine production by mononuclear cells from allergic patients. J. Allergy Clin. Immunol.110, 617–623 (2002).
   PubMed Web of Science ®Google Scholar
• Grangette C, Nutten S, Palumbo E et al. Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids. Proc. Natl. Acad. Sci. USA102, 10321–10326 (2005).
   PubMed Web of Science ®Google Scholar
• Okamoto N, Tezuka K, Kato M, Abe R, Tsuji T. PI3-kinase and MAP-kinase signaling cascades in AILIM/ICOS- and CD28-costimulated T-cells have distinct functions between cell proliferation and IL-10 production. Biochem. Biophys. Res. Commun.310, 691–702 (2003).
   PubMed Web of Science ®Google Scholar
• Yang DD, Conze D, Whitmarsh AJ et al. Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. Immunity9, 575–585 (1998).
   PubMed Web of Science ®Google Scholar
• Dillon S, Agrawal S, Banerjee K et al. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J. Clin. Invest.116, 916–928 (2006).
   PubMed Web of Science ®Google Scholar
• Agrawal A, Dillon S, Denning TL, Pulendran B. ERK1-/- mice exhibit Th1 cell polarization and increased susceptibility to experimental autoimmune encephalomyelitis. J. Immunol.176, 5788–5796 (2006).
   PubMed Web of Science ®Google Scholar
• Christensen HR, Frokiaer H, Pestka JJ. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol.168, 171–178 (2002).
   PubMed Web of Science ®Google Scholar
• Janeway CA Jr. A trip through my life with an immunological theme. Annu. Rev. Immunol.20, 1–28 (2002).
   PubMed Web of Science ®Google Scholar
• Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu. Rev. Immunol.20, 197–216 (2002).
   PubMed Web of Science ®Google Scholar
• Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science296, 298–300 (2002).
   PubMed Web of Science ®Google Scholar
• Kawai T, Akira S. TLR signaling. Semin. Immunol.19, 24–32 (2007).
   PubMed Web of Science ®Google Scholar
• Akira S. TLR signaling. Curr. Top. Microbiol. Immunol.311, 1–16 (2006).
   PubMed Web of Science ®Google Scholar
• Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell124, 783–801 (2006).
   PubMed Web of Science ®Google Scholar
• Thoma-Uszynski S, Kiertscher SM, Ochoa MT et al. Activation of Toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10. J. Immunol.165, 3804–3810 (2000).
   PubMed Web of Science ®Google Scholar
• Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D. Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol.163, 1–5 (1999).
   PubMed Web of Science ®Google Scholar
• Hoebe K, Du X, Georgel P et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature424, 743–748 (2003).
   PubMed Web of Science ®Google Scholar
• Hoebe K, Janssen EM, Kim SO et al. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat. Immunol.4, 1223–1229 (2003).
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Duong T, Hoover T, Klaenhammer TR. Targeting mucosal dendritic cells with microbial antigens from probiotic lactic acid bacteria. Expert Rev. Vaccines7(2), 163–174 (2008).
   PubMed Web of Science ®Google Scholar
• Wells JM, Mercenier A. Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria. Nat. Rev. Microbiol.6, 349–362 (2008).
   PubMed Web of Science ®Google Scholar