312
Views
6
CrossRef citations to date
0
Altmetric
Drug Profile

Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD

Pages 1115-1124 | Published online: 10 Jan 2014

References

  • Chobanian AV, Bakris GL, Black HR et al. Seventh report of the National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42, 1206–1252 (2003).
  • Mancia G, De Backer G, Dominiczak A et al. 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. J. Hypertens. 25, 1751–1762 (2007).
  • Chrysant SG. Stopping the cardiovascular disease continuum: focus on prevention. World J. Cardiol. 2, 43–49 (2010).
  • Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 365, 217–223 (2005).
  • Roger VL, Go AS, Lloyd-Jones et al. Heart disease and stroke statistics – 2012 update: a report from the American Heart Association. Circulation 25, e2–e220 (2012).
  • Bakris GL, Sowers JR, Giles TD et al. Treatment of hypertension in patients with diabetes – an update. J. Am. Soc. Hypertens. 4, 62–67 (2010).
  • Rosendorff C, Black HR, Cannon CP et al. Treatment of hypertension in the prevention and management of ischemic heart disease: a scientific statement from the American Heart Association Council for High Blood Pressure Research and the Council on Clinical Cardiology and Epidemiology and Prevention. Circulation 115, 2761–2788 (2007).
  • Lewington S, Clarke R, Qizilbash N et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360, 1903–1913 (2002).
  • Bertoia ML, Waring ME, Gupta PS, Roberts MB, Eaton CB. Implications of new hypertension guidelines in the United States. Hypertension 58, 361–366 (2011).
  • Gradman AH. Rationale for triple combination therapy for management of high blood pressure. J. Clin. Hypertens. 12, 869–878 (2010).
  • Chrysant SG. Using fixed-dose combination therapies to achieve blood pressure goals. Clin. Drug Investig. 28, 713–734 (2008).
  • Gradman AH, Basile JN, Carter BL, Bakris GL. Combination therapy in hypertension. J. Am. Soc. Hypertens. 4, 42–50 (2010).
  • Bangalore S, Kamalakkanan G, Parkar S, Messerli FH. Fixed-dose combinations improve medication compliance: a meta-analysis. Am. J. Med. 120, 713–719 (2007).
  • Panjabi S, Lacey M, Bancroft T, Gao F. Treatment adherence, clinical outcomes, and economics of triple-drug therapy in hypertensive patients. J. Am. Soc. Hypertens. 7, 46–60 (2013).
  • Oparil S, Chrysant SG, Melino M, Lee J, Karki S, Heyrman R. Long-term efficacy of a combination of amlodipine and olmesartan medoxomil ± hydrochlorothiazide in patients with hypertension stratified by age, race and diabetes status: a sub study of the COACH trial. J. Hum. Hypertens. 24, 831–838 (2010).
  • Oparil S, Melino M, Lee J, Fernandez V, Heyrman R. Triple therapy with olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide in adult patients with hypertension: The TRINITY multicenter, randomized, double-blind, 12-week, parallel-group study. Clin. Ther. 32, 1252–1269 (2010).
  • Deeks ED. Olmesartan medoxomil/amlodipine/hydrochlorothiazide fixed-dose combination in hypertension. Drugs 71, 209–220 (2011).
  • Scott LJ, Mc Cormack PL. Olmesartan medoxomil: a review of its use in the management of hypertension. Drugs 68, 1239–1272 (2008).
  • Haria M, Wagstaff AJ. Amlodipine: a reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease. Drugs 50, 560–566 (1995).
  • Chrysant SG, Weber MA, Wang AC, Hinman DJ. Evaluation of antihypertensive therapy with the combination of olmesartan medoxomil and hydrochlorothiazide. Am. J. Hypertens. 17, 252–259 (2004).
  • Beermann B, Groschinsky-Grind M. Pharmacokinetics of hydrochlorothiazide in man. Eur. J. Clin. Pharmacol. 12, 297–303 (1977).
  • Ausubel H, Levine ML. Treatment of hypertension with Ser-Ap-Es. Curr. Ther. Res. Clin. Exp. 9, 29–35 (1967).
  • Moser M. From JNC 1-JNC 7: what have we learned? Prog. Cardiovasc. Dis. 48, 303–315 (2006).
  • Fagan TC. Remembering the lessons of basic pharmacology. Arch. Intern. Med. 1541430–1431 (1994).
  • Materson BJ, Reda DJ, Cushman WC et al. Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. N. Engl. J. Med. 328, 914–992 (1993).
  • Chrysant SG, Oparil S, Melino M, Lee J, Fernandez V, Heyrman R. Efficacy and safety of long-term treatment with the combination of amlodipine besylate and olmesartan medoxomil in patients with hypertension. J. Clin. Hypertens. 11, 475–482 (2009).
  • Chrysant SG, Melino M, Karki S, Lee J, Heyrman R. The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety study. Clin. Ther. 30, 587–604 (2008).
  • Izzo JL, Chrysant SG, Kereiakes DJ et al. 24-H efficacy and safety of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy. J. Clin. Hypertens. 13, 873–880 (2011).
  • Volpe M, Miele C, Haag U. Efficacy and safety of a stepped-care regimen using olmesartan medoxomil, amlodipine and hydrochlorothiazide in patients with moderate-to-severe hypertension: an open-label long-term study. Clin. Drug Invest. 29, 381–391 (2009).
  • Weir MR, Hsue WA, Nesbitt SD et al. A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixer-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide. J. Clin. Hypertens. 13, 404–412 (2011).
  • Neutel JM, Smith DHG, Weber MA, Wang AC, Masonson HN. Use of an olmesartan medoxomil-based treatment algorithm for hypertension control. J. Clin. Hypertens. 6, 168–174 (2004).
  • Calhoun DA, Lacourciere Y, Chiang YT, Glazer RD. Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial. Hypertension 54, 32–39 (2009).
  • Lacourciere Y, Crikelait N, Glazer RD, Yen J, Calhoun DA. 24-h ambulatory blood pressure control with the triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension. J. Hum. Hypertens. 25, 615–522 (2011).
  • Destro M, Luckow A, Samson M, Kandra A, Brunel P. Efficacy and safety of amlodipine/valsartan compared with amlodipine monotherapy in patients with stage 2 hypertension: a randomized, double-blind, multicenter study: the EX-EFFeCTS Study. J. Am. Soc. Hypertens. 2, 294–302 (2008).
  • Flack JM, Calhoun DA, Satlin L, Barbier M, Hilkert R, Brunel P. Efficacy and safety of initial combination therapy with amlodipine/valsartan compared with amlodipine monotherapy in black patients with stage 2 hypertension: the EX-STAND Study. J. Hum. Hypertens. 23, 479–489 (2009).
  • Allemann Y, Fraile B, Lambert M, Barbier M, Ferber P, Izzo JL. Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: The Exforge in Failure after Single Therapy (EX-FAST) Study. J. Clin. Hypertens. 10, 185–194 (2008).
  • Lacourciere Y, Taddei S, Konis G, Fang H, Severin T, Zhang J. Clinic and ambulatory blood pressure lowering effect of aliskiren/amlodipine/hydrochlorothiazide combination in patients with moderate-to-severe hypertension: a randomized active-controlled trial. J. Hypertens. 30, 2047–2055 (2012).
  • Kereiakes DJ, Chrysant SG, Izzo JL et al. Olmesartan/amlodipine/hydrochlorothiazide in participants with hypertension and diabetes, chronic kidney disease, or chronic cardiovascular disease: a subanalysis of the multi center, randomized, double-blind, parallel-group TRINITY study. Cardiovasc. Diabetol. 11, 134 (2012).
  • Oparil S, Chrysant SG, Melino M, Lee J, Karki S, Heyrman R. Long-term efficacy of a combination of amlodipine and olmesartan medoxomil in patients with hypertension stratified by age, race and diabetes: a sub-study of the COACH trial. J. Hum. Hypertens. 24, 831–838 (2010).
  • Yannakopoulou E, Papadopoulos JS, Cokkinos DV, Mantokalakis TD. Adherence to antihypertensive treatment: a critical factor for blood pressure control. Eur. J. Cardovasc. Rev. Rehabbil. 12, 243–249 (2005).
  • Fung V, Huang J, Brand R, Newhouse JP, Hsu J. Hypertension treatment in a Medicare population: adherence and systolic blood pressure control. Clin. Ther. 29, 972–984 (2007).
  • Williams B, Lacy PS, Thom SM et al. Differential impact of blood pressure lowering drugs and control of aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFÉ) study. Circulation 113, 1213–1225 (2007).
  • Agapiti-Rosei M, Mancia G, O’Rourke MF et al. Central blood pressure measurements and antihypertensive therapy. A consensus document. Hypertension 50, 154–160 (2007).
  • Kim-Mitsuyama S, Ogawa H, Matsui K, Jinnouchi T, Jinnouchi H, Arakawa K, for the OSCAR Study Group. An angiotensin II receptor blocker- calcium channel blocker combination prevents cardiovascular events in elderly high-risk hypertensive patients with chronic kidney disease better than high-dose angiotensin II receptor blockade alone. Kidney Int. 83, 167–176 (2013).
  • Cooper-DeHoff RM, Gong Y, Hanberg EM et al. Tight blood pressure control on cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. JAMA 304, 61–68 (2010).
  • Cushman WC, Evans GW, Byington RP et al. Effects of intensive blood pressure control in Type 2 diabetes mellitus. N. Engl. J. Med. 362, 1575–1585 (2010).
  • Safar ME, Balkau B, Lange C et al. Hypertension and vascular dynamics in men and women with the metabolic syndrome. J. Am. Coll. Cardiol. 61, 12–19 (2013).
  • Sleight P, Redon J, Verdecchia P et al.; on behalf of the ONTARGET Investigators. Prognostic value of blood pressure in patients with vascular risk. In the Ongoing Telmisartan alone and in Combination with Ramipril Global Endpoint Trial study. J. Hypertens. 27, 1360–1369 (2009).
  • Mancia G, Laurent S, Agapiti-Rosei E et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J. Hypertens. 27, 2121–215 (2009).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.