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Review

Impact of tobacco smoking and smoking cessation on cardiovascular risk and disease

Pages 883-895 | Published online: 10 Jan 2014

References

  • Ezzati M, Lopez AD. Regional, disease specific patterns of smoking-attributable mortality in 2000. Tob. Control13(4), 388–395 (2004).
  • Jha P, Chaloupka FJ, Moore J et al. Tobacco Addiction. In: Disease Control Priorities in Developing Countries. Jamison DT, Bregman JG, Measham A (Ed.). Oxford University Press, World Bank, NY, USA, 869–885 (2006).
  • Yusuf S, Hawken S, Ounpuu S et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case–control study. Lancet364(9438), 937–952 (2004).
  • World Health Organisation. MPOWER. WHO Report on the Global Tobacco Epidemic. World Health Organisation, Geneva (2008).
  • Doll R, Peto R, Wheatley K, Gray R, Sutherland I. Mortality in relation to smoking: 40 years’ observations on male British doctors. Br. Med. J.309(6959), 901–911 (1994).
  • Hammond EC, Garfinkel L. Coronary heart disease, stroke, and aortic aneurysm. Arch. Environ. Health19(2), 167–182 (1969).
  • US Department of Health Education and Welfare. Smoking and health: report of the Advisory Committee to the Surgeon General of the Public Health Service. In: PHS Publication (Eds). US Department of Health, Education and Welfare Public Health Service, DC, USA (1964).
  • Benowitz NL. Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Prog. Cardiovasc. Dis.46(1), 91–111 (2003).
  • Teo KK, Ounpuu S, Hawken S et al. Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case–control study. Lancet368(9536), 647–658 (2006).
  • Burns DM. Epidemiology of smoking-induced cardiovascular disease. Prog. Cardiovasc. Dis.46(1), 11–29 (2003).
  • Metz L, Waters DD. Implications of cigarette smoking for the management of patients with acute coronary syndromes. Prog. Cardiovasc. Dis.46(1), 1–9 (2003).
  • Nakamura K, Barzi F, Lam T et al. Cigarette smoking, systolic blood pressure, and cardiovascular diseases in the Asia-Pacific Region. Stroke39(6), 1694–1702 (2008).
  • Willett WC, Green A, Stampfer MJ et al. Relative and absolute excess risks of coronary heart disease among women who smoke cigarettes. N. Engl. J. Med.317(21), 1303–1309 (1987).
  • Benowitz NL, Hall SM, Herning RI et al. Smokers of low-yield cigarettes do not consume less nicotine. N. Engl. J. Med.309(3), 139–142 (1983).
  • Jacobs EJ, Thun MJ, Apicella LF. Cigar smoking and death from coronary heart disease in a prospective study of US men. Arch. Internal Med.159(20), 2413–2418 (1999).
  • Iribarren C, Tekawa IS, Sidney S, Friedman GD. Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men. N. Engl. J. Med.340(23), 1773–1780 (1999).
  • Bjartveit K, Tverdal A. Health consequences of smoking 1–4 cigarettes per day. Tob. Control,14, 315–320 (2005).
  • Negri E, La Vecchia C, Nobili A, D’Avanzo B, Bechi S. Cigarette smoking and acute myocardial infarction. A case–control study from the GISSI-2 trial. GISSI-EFRIM Investigators. Eur. J. Epidemiol.10(4), 361–366 (1994).
  • Law MR, Morris JK, Wald NJ. Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence. Br. Med. J.315(7114), 973–980 (1997).
  • Wannamethee G, Shaper AG, Macfarlane PW, Walker M. Risk factors for sudden cardiac death in middle-aged British men. Circulation91(6), 1749–1756 (1995).
  • Hasdai D, Garratt KN, Grill DE, Lerman A, Holmes DR, Jr. Effect of smoking status on the long-term outcome after successful percutaneous coronary revascularization. N. Engl. J. Med.336(11), 755–761 (1997).
  • Price JF, Mowbray PI, Lee AJ et al. Relationship between smoking and cardiovascular risk factors in the development of peripheral arterial disease and coronary artery disease: Edinburgh Artery Study. Eur. Heart J.20(5), 344–353 (1999).
  • Kannel WB, Shurtleff D. The Framingham Study. Cigarettes and the development of intermittent claudication. Geriatrics28(2), 61–68 (1973).
  • Hankey GJ, Norman PE, Eikelboom JW. Medical treatment of peripheral arterial disease. JAMA295(5), 547–553 (2006).
  • Hooi JD, Kester AD, Stoffers HE et al. Incidence of and risk factors for asymptomatic peripheral arterial occlusive disease: a longitudinal study. Am. J. Epidemiol.153(7), 666–672 (2001).
  • Hooi JD, Stoffers HE, Knottnerus JA, van Ree JW. The prognosis of non-critical limb ischaemia: a systematic review of population-based evidence. Br. J. Gen. Pract.49(438), 49–55 (1999).
  • Hooi JD, Stoffers HE, Kester AD et al. Risk factors and cardiovascular diseases associated with asymptomatic peripheral arterial occlusive disease. The Limburg PAOD Study. Peripheral Arterial Occlusive Disease. Scand. J. Prim. Health Care16(3), 177–182 (1998).
  • Bendermacher BLW, Willigendael EM, Teijink JAW, Prins MH. Medical management of peripheral arterial disease. J. Thromb. Haemost.3(8), 1628–1637 (2005).
  • Willigendael EM, Teijink JAW, Bartelink M-L et al. Smoking and the patency of lower extremity bypass grafts: a meta-analysis. J. Vasc. Surg.42(1), 67–74 (2005).
  • Kazmers A, Kohler TR. Very late survival after vascular surgery. J. Surg. Res.105(2), 109–114 (2002).
  • Witteman JC, Grobbee DE, Valkenburg HA et al. Cigarette smoking and the development and progression of aortic atherosclerosis. A 9-year population-based follow-up study in wom en. Circulation88(5 Pt 1), 2156–2162 (1993).
  • Brady AR, Thompson SG, Fowkes FGR et al. Abdominal aortic aneurysm expansion: risk factors and time intervals for surveillance. Circulation110(1), 16–21 (2004).
  • Vardulaki KA, Walker NM, Day NE et al. Quantifying the risks of hypertension, age, sex and smoking in patients with abdominal aortic aneurysm. Br. J. Surg.87(2), 195–200 (2000).
  • Lederle FA, Nelson DB, Joseph AM. Smokers’ relative risk for aortic aneurysm compared with other smoking-related diseases: a systematic review. J. Vasc. Surg.38(2), 329–334 (2003).
  • Iribarren C, Darbinian JA, Go AS et al. Traditional and novel risk factors for clinically diagnosed abdominal aortic aneurysm: The Kaiser Multiphasic Health Checkup Cohort Study. Ann. Epidemiol.17, 669–678 (2007).
  • Kurth T, Kase CS, Berger K et al. Smoking and risk of hemorrhagic stroke in women. Stroke34(12), 2792–2795 (2003).
  • Hart CL, Hole DJ, Smith GD. Risk factors and 20-year stroke mortality in men and women in the Renfrew/Paisley study in Scotland. Stroke30(10), 1999–2007 (1999).
  • Colditz GA, Bonita R, Stampfer MJ et al. Cigarette smoking and risk of stroke in middle-aged women. N. Engl. J. Med.318(15), 937–941 (1988).
  • Kelly T, Gu D, Chen J et al. Cigarette smoking and risk of stroke in the Chinese adult population. Stroke39(6), 1688–1693. (2008).
  • Goldstein LB, Adams R, Alberts MJ et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council. Stroke37(6), 1583–1633 (2006).
  • Haustein K. Tobacco or Health: Physiological and Social Damages Caused by Tobacco Smoking. Springer, Berlin, Germany (2002).
  • Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J. Am. Coll. Cardiol.43(10), 1731–1737 (2004).
  • Benowitz NL. Nicotine Safety and Toxicity. Oxford University Press, NY, USA (1998).
  • Beere PA, Glagov S, Zarins CK. Retarding effect of lowered heart rate on coronary atherosclerosis. Science226(4671), 180–182 (1984).
  • Asplund K. Smokeless tobacco and cardiovascular disease. Prog. Cardiovasc. Dis.45(5), 383–394 (2003).
  • Benowitz NL, Porchet H, Sheiner L, Jacob P 3rd. Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clin. Pharmacol. Ther.44(1), 23–28 (1988).
  • Eliasson M, Lundblad D, Hagg E. Cardiovascular risk factors in young snuff-users and cigarette smokers. J. Intern. Med.230(1), 17–22. (1991).
  • Benowitz NL, Gourlay SG. Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. J. Am. Coll. Cardiol.29(7), 1422–1431 (1997).
  • FitzGerald GA, Oates JA, Nowak J. Cigarette smoking and hemostatic function. Am. Heart J.115(1 Pt 2), 267–271 (1988).
  • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N. Engl. J. Med.326(5), 310–318 (1992).
  • Ernst E, Koenig W, Matrai A, Filipiak B, Stieber J. Blood rheology in healthy cigarette smokers. Results from the MONICA project, Augsburg. Arteriosclerosis8(4), 385–388 (1988).
  • Kannel WB, Wolf PA, Castelli WP, D’Agostino RB. Fibrinogen and risk of cardiovascular disease. The Framingham Study. JAMA258(9), 1183–1186 (1987).
  • Ernst E. Fibrinogen: its emerging role as a cardiovascular risk factor. Angiology45(2), 87–93 (1994).
  • Wilhelmsen L. Coronary heart disease: epidemiology of smoking and intervention studies of smoking. Am. Heart J.115(1 Pt 2), 242–249 (1988).
  • Sambola A, Osende J, Hathcock J et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity. Circulation107(7), 973–977 (2003).
  • Burke A, Fitzgerald GA. Oxidative stress and smoking-induced vascular injury. Prog. Cardiovasc. Dis.46(1), 79–90 (2003).
  • Heitzer T, Just H, Munzel T. Antioxidant vitamin C improves endothelial dysfunction in chronic smokers. Circulation94(1), 6–9 (1996).
  • Stamatelopoulos KS, Lekakis JP, Papamichael CM et al. Oral administration of ascorbic acid attenuates endothelial dysfunction after short-term cigarette smoking. Int. J. Vitam. Nutr. Res.73(6), 417–422 (2003).
  • Lehr HA, Weyrich AS, Saetzler RK et al. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J. Clin. Invest.99(10), 2358–2364 (1997).
  • Zhang J, Ying X, Lu Q et al. A single high dose of vitamin C counteracts the acute negative effect on microcirculation induced by smoking a cigarette. Microvasc. Res.58(3), 305–311 (1999).
  • Katayama Y, Shige H, Yamamoto A, Hirata F, Yasuda H. Oral vitamin C ameliorates smoking-induced arterial wall stiffness in healthy volunteers. J. Atheroscler. Thromb.11(6), 354–357 (2004).
  • Stadler N, Eggermann J, Voo S, Kranz A, Waltenberger J. Smoking-induced monocyte dysfunction is reversed by vitamin C supplementation in vivo. Arterioscler. Thromb. Vasc. Biol.27(1), 120–126 (2007).
  • Duthie GG, Arthur JR, Beattie JA et al. Cigarette smoking, antioxidants, lipid peroxidation, and coronary heart disease. Ann. NY Acad. Sci.686, 120–129 (1993).
  • Harats D, Ben-Naim M, Dabach Y et al. Cigarette smoking renders LDL susceptible to peroxidative modification and enhanced metabolism by macrophages. Atherosclerosis79(2–3), 245–252 (1989).
  • Barua RS, Ambrose JA, Eales-Reynolds LJ et al. Dysfunctional endothelial nitric oxide biosynthesis in healthy smokers with impaired endothelium-dependent vasodilatation. Circulation104(16), 1905–1910 (2001).
  • Celermajer DS, Sorensen KE, Georgakopoulos D et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation88(5 Pt 1), 2149–2155 (1993).
  • Higman DJ, Greenhalgh RM, Powell JT. Smoking impairs endothelium-dependent relaxation of saphenous vein. Br. J. Surg.80(10), 1242–1245 (1993).
  • Kiowski W, Linder L, Stoschitzky K et al. Diminished vascular response to inhibition of endothelium-derived nitric oxide and enhanced vasoconstriction to exogenously administered endothelin-1 in clinically healthy smokers. Circulation90(1), 27–34 (1994).
  • Petitti DB, Kipp H. The leukocyte count: associations with intensity of smoking and persistence of effect after quitting. Am. J. Epidemiol.123(1), 89–95 (1986).
  • Lavi S, Prasad A, Yang EH et al. Smoking is associated with epicardial coronary endothelial dysfunction and elevated white blood cell count in patients with chest pain and early coronary artery disease. Circulation115(20), 2621–2627 (2007).
  • Grimm RH Jr, Neaton JD, Ludwig W. Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality. JAMA254(14), 1932–1937 (1985).
  • Lam TH, Stewart SM, Ho SY et al. Depressive symptoms and smoking among Hong Kong Chinese adolescents. Addiction100(7), 1003–1011 (2005).
  • Hansen PR. Role of neutrophils in myocardial ischemia and reperfusion. Circulation91(6), 1872–1885 (1995).
  • Waters D, Lesperance J, Gladstone P et al.; CCAIT Study Group. Effects of cigarette smoking on the angiographic evolution of coronary atherosclerosis. A Canadian Coronary Atherosclerosis Intervention Trial (CCAIT) Substudy. Circulation94(4), 614–621 (1996).
  • Howard G, Wagenknecht LE, Burke GL et al. Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study. JAMA279(2), 119–124 (1998).
  • He J, Vupputuri S, Allen K et al. Passive smoking and the risk of coronary heart disease – a meta-analysis of epidemiologic studies. N. Engl. J. Med.340(12), 920–926 (1999).
  • Barnoya J, Glantz SA. Cardiovascular effects of secondhand smoke: nearly as large as smoking. Circulation111(20), 2684–2698 (2005).
  • Bonita R, Duncan J, Truelsen T, Jackson RT, Beaglehole R. Passive smoking as well as active smoking increases the risk of acute stroke. Tob. Control8(2), 156–160 (1999).
  • Donnan GA, McNeil JJ, Adena MA et al. Smoking as a risk factor for cerebral ischaemia. Lancet2(8664), 643–647 (1989).
  • Whincup PH, Gilg JA, Emberson JR et al. Passive smoking and risk of coronary heart disease and stroke: prospective study with cotinine measurement. Br. Med. J.329(7459), 200–205 (2004).
  • Iribarren C, Darbinian JA, Klatsky AL, Friedman GD. Cohort study of exposure to environmental tobacco smoke exposure and risk of first ischemic stroke and transient ischemic attack. Neuroepidemiology23, 8–44 (2007).
  • Wang XL, Raveendran M, Wang J. Genetic influence on cigarette-induced cardiovascular disease. Prog. Cardiovasc. Dis.45(5), 361–382 (2003).
  • Thorgeirsson TE, Geller F, Sulem P et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature452(7187), 638–642 (2008).
  • Lou XY, Ma JZ, Sun D et al. Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European–Americans. Hum. Mol. Genet.16(2), 142–153 (2007).
  • Saccone S, Hinrichs AL, Saccone NL et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum. Mol. Genet.16(1), 36–49 (2007).
  • Critchley JA, Capewell S. Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review. JAMA290(1), 86–97 (2003).
  • Peters RW, Brooks MM, Todd L, Liebson PR, Wilhelmsen L; The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Smoking cessation and arrhythmic death: the CAST experience. J. Am. Coll. Cardiol.26(5), 1287–1292 (1995).
  • Hallstrom AP, Cobb LA, Ray R. Smoking as a risk factor for recurrence of sudden cardiac arrest. N. Engl. J. Med.314(5), 271–275 (1986).
  • Jonason T, Bergstrom R. Cessation of smoking in patients with intermittent claudication. Effects on the risk of peripheral vascular complications, myocardial infarction and mortality. Acta Med. Scand.221(3), 253–260 (1987).
  • Robbins AS, Manson JE, Lee IM, Satterfield S, Hennekens CH. Cigarette smoking and stroke in a cohort of U.S. male physicians. Ann. Intern. Med.120(6), 458–462 (1994).
  • Kenfield S, Stampfer M, Rosner B, Colditz G. Smoking and smoking cessation in relation to mortality in women. JAMA299, 2037–2047(2008).
  • Lightwood JM, Glantz SA. Short-term economic and health benefits of smoking cessation: myocardial infarction and stroke. Circulation96(4), 1089–1096 (1997).
  • Hunter KA, Garlick PJ, Broom I, Anderson SE, McNurlan MA. Effects of smoking and abstention from smoking on fibrinogen synthesis in humans. Clin. Sci. (Colch.)100(4), 459–465 (2001).
  • Terres W, Becker P, Rosenberg A. Changes in cardiovascular risk profile during the cessation of smoking. Am. J. Med.97(3), 242–249 (1994).
  • Morita H, Ikeda H, Haramaki N, Eguchi H, Imaizumi T. Only two-week smoking cessation improves platelet aggregability and intraplatelet redox imbalance of long-term smokers. J. Am. Coll. Cardiol.45(4), 589–594 (2005).
  • Eliasson B, Hjalmarson A, Kruse E, Landfeldt B, Westin A. Effect of smoking reduction and cessation on cardiovascular risk factors. Nicotine Tob. Res.3(3), 249–255 (2001).
  • Stubbe I, Eskilsson J, Nilsson-Ehle P. High-density lipoprotein concentrations increase after stopping smoking. Br. Med. J. (Clin. Res. Ed.)284(6328), 1511–1513 (1982).
  • Oren S, Isakov I, Golzman B et al. The influence of smoking cessation on hemodynamics and arterial compliance. Angiology57(5), 564–568 (2006).
  • Law MR, Wald NJ. Environmental tobacco smoke and ischemic heart disease. Prog. Cardiovasc. Dis.46(1), 31–38 (2003).
  • Lightwood J. The economics of smoking and cardiovascular disease. Prog. Cardiovasc. Dis.46(1), 39–78 (2003).
  • Brown AI, Garber AM. A concise review of the cost–effectiveness of coronary heart disease prevention. Med. Clin. North Am.84(1), 279–297 (2000).
  • Prignot J, Bartsch P, Vermeire P et al. Physician’s involvement in the smoking cessation process of their patients. Results of a 1998 survey among 4,643 Belgian physicians. Acta Clin. Belg.55(5), 266–275 (2000).
  • Hasdai D, Garratt KN, Grill DE et al. Predictors of smoking cessation after percutaneous coronary revascularization. Mayo Clin. Proc.73(3), 205–209 (1998).
  • Holtzman JL, Weeks CE, Kvam DC et al. Identification of drug interactions by meta-analysis of premarketing trials: the effect of smoking on the pharmacokinetics and dosage requirements for flecainide acetate. Clin. Pharmacol. Ther.46(1), 1–8 (1989).
  • Walle T, Walle UK, Cowart TD, Conradi EC, Gaffney TE. Selective induction of propranolol metabolism by smoking: additional effects on renal clearance of metabolites. J. Pharmacol. Exp. Ther.241(3), 928–933 (1987).
  • Nam CM, Oh KW, Lee KH et al. Vitamin C intake and risk of ischemic heart disease in a population with a high prevalence of smoking. J. Am. Coll. Nutr.22(5), 372–378 (2003).
  • Evans RW, Shaten BJ, Day BW, Kuller LH. Prospective association between lipid soluble antioxidants and coronary heart disease in men: the multiple risk factor intervention trial. Am. J. Epidemiol., 147(2), 180–186 (1998).
  • Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet361(9374), 2017–2023 (2003).
  • Moller AM, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet359(9301), 114–117 (2002).
  • Fiore MC, Jaen CR, Baker TB et al.Treating Tobacco Use and Dependence: 2008 Update. US Department of Health and Human Services. Public Health Service, MD, USA (2008).
  • Silagy C, Stead L. Physician advice for smoking cessation (Cochrane Review). Cochrane Database Syst. Rev. (2), CD000165 (2001).
  • Anderson JE, Jorenby DE, Scott WJ, Fiore MC. Treating tobacco use and dependence: an evidence-based clinical practice guideline for tobacco cessation. Chest121(3), 932–941 (2002).
  • Fagerstrom K, Balfour DJK. Neuropharmacology and potential efficacy of new treatments for tobacco dependence. Expert Opin. Investig. Drugs15(2), 107–116 (2006).
  • Balfour D, Benowitz N, Fagerstrom K, Kunze M, Keil U. Diagnosis and treatment of nicotine dependence with emphasis on nicotine replacement therapy. A status report Eur. Heart J.21(6), 438–445 (2000).
  • Stead L, Perera R, Bullen C, Mant D, Lancaster T. Nicotine replacement therapy for smoking cessation. Cochrane Database Syst. Rev.1, CD000146 (2008).
  • Molyneux A, Lewis S, Leivers U et al. Clinical trial comparing nicotine replacement therapy (NRT) plus brief counselling, brief counselling alone, and minimal intervention on smoking cessation in hospital inpatients. Thorax58(6), 484–488 (2003).
  • McRobbie H, Hajek P. Nicotine replacement therapy in patients with cardiovascular disease: guidelines for health professionals. Addiction96(11), 1547–1551 (2001).
  • Benowitz NL, Chan K, Denaro CP, Jacob P 3rd. Stable isotope method for studying transdermal drug absorption: the nicotine patch. Clin. Pharmacol. Ther.50(3), 286–293 (1991).
  • Meine TJ, Patel MR, Washam JB, Pappas PA, Jollis JG. Safety and effectiveness of transdermal nicotine patch in smokers admitted with acute coronary syndromes. Am. J. Cardiol.95(8), 976–978 (2005).
  • McRobbie H. Current insights and new opportunities for smoking cessation. Br. J. Cardiol.12(1), 37–44 (2005).
  • Royal College of Physicians. Nicotine Addiction in Britain. Royal College of Physicians, London, UK (2000).
  • Jorenby DE, Leischow SJ, Nides MA et al. A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. N. Engl. J. Med.340(9), 685–691 (1999).
  • West R. Bupropion SR for smoking cessation. Expert Opin. Pharmacother.4(4), 533–540 (2003).
  • Tonstad S, Farsang C, Klaene G et al. Bupropion SR for smoking cessation in smokers with cardiovascular disease: a multicentre, randomised study. Eur. Heart J.24(10), 946–955 (2003).
  • Roddy E. Bupropion and other non-nicotine pharmacotherapies. Br. Med. J.328(7438), 509–511 (2004).
  • Jorenby DE, Hays JT, Rigotti NA et al. Efficacy of varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA296(1), 56–63 (2006).
  • Coe JW, Brooks PR, Vetelino MG et al. Varenicline: an α4β2 nicotinic receptor partial agonist for smoking cessation. J. Med. Chem.48(10), 3474–3477 (2005).
  • Nides M. Efficacy and safety of varenicline for smoking cessation. In: 1st UK National Smoking Cessation Conference. London, UK (2005)
  • Kuehn B. FDA warns of adverse events linked to smoking cessation drug and antiepileptics. JAMA299(10), 1121–1122 (2008).
  • McRobbie H, Lee M, Juniper Z. Non-nicotine pharmacotherapies for smoking cessation. Respir. Med.99(10), 1203–1212 (2005).
  • Roose SP, Laghrissi-Thode F, Kennedy JS et al. Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease. JAMA279(4), 287–291 (1998).
  • White AR, Rampes H, Campbell JL. Acupuncture and related interventions for smoking cessation. Cochrane Database Syst. Rev.1, CD000009 (2006).
  • Abbot NC, Stead LF, White AR, Barnes J. Hypnotherapy for smoking cessation. Cochrane Database Syst. Rev.1, 1–15 (2006).
  • Sargent RP, Shepard RM, Glantz SA. Reduced incidence of admissions for myocardial infarction associated with public smoking ban: before and after study. Br. Med. J.328(7446), 977–980 (2004).
  • Bartecchi C, Alsever RN, Nevin-Woods C et al. Reduction in the incidence of acute myocardial infarction associated with a citywide smoking ordinance. Circulation114(14), 1490–1496 (2006).
  • Khuder SA, Milz S, Jordan T et al. The impact of a smoking ban on hospital admissions for coronary heart disease. Prev. Med.45(1), 3–8 (2007).
  • Barnoya J, Bialous SA, Glantz SA. Effective interventions to reduce smoking-induced heart disease around the world: time to act. Circulation112(4), 456–458 (2005).
  • Stead LF, Perera R, Lancaster T. A systematic review of interventions for smokers who contact quitlines. Tob. Control16(Suppl. 1), i3–i8 (2007).
  • Zhu SH, Anderson C, Tedeschi G et al. Evidence of real-world effectiveness of a telephone quitline for smokers. N. Engl. J. Med.347(14), 1087–1093 (2002).
  • Rodgers A, Corbett T, Bramley D et al. Do u smoke after txt? Results of a randomised trial of smoking cessation using mobile phone text messaging. Tob. Control14(4), 255–261 (2005).
  • Rigotti NA, Munafo MR, Stead LF. Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst. Rev.3, CD001837 (2007).
  • Hyland A, Rezaishiraz H, Giovino G et al. Over-the-counter availability of nicotine replacement therapy and smoking cessation. Nicotine Tob. Res.7(4), 547–555 (2005).
  • Waitzkin H. One and a half centuries of forgetting and rediscovering: virchow’s lasting contributions to social medicine. Social Med.1(1), 5–10 (2006).
  • World Health Organisation. Chapter 5. Building capacity for smoking cessation and treatment of tobacco dependence. In: Policy Recommendations for Smoking Cessation and Treatment of Tobacco Dependence. Silva, VdCe (Ed.). WHO, Geneva, Switzerland (2003).
  • Bullen C, Whittaker R, McRobbie H, Fagerstrom K. A clinical imperative: assisting patients who smoke to reduce their risk of cardiovascular disease. Prev. Cardiol.10(2 Suppl. 1), 5–9 (2007).
  • Fagerstrom K, Balfour DJK. Neuropharmacology and potential efficacy of new treatments for tobacco dependence. Expert Opin. Investig. Drugs15(2), 107–116 (2006).
  • Fagerstrom K. New perspectives in the treatment of tobacco dependence. Monaldi Arch. Chest Dis.60(3), 179–183 (2003).
  • Siu E, Tyndale R. Selegiline is a mechanism-based inactivator of CYP2A6 inhibting nicotine metabolism in humans and mice. J. Pharmacol. Exp. Ther.324, 992–999 (2008).
  • Cahill K, Ussher M. Cannabinoid type 1 receptor antagonists (rimonabant) for smoking cessation. Cochrane Database Syst. Rev. (4), CD005353 (2007).
  • Etter J-F. Cytisine for smoking cessation: a literature review and a meta-analyis. Arch. Intern. Med.166(15), 1553–1559 (2006).

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