Advanced search
Publication Cover
Expert Review of Proteomics Volume 1, 2004 - Issue 2
Submit an article Journal homepage
13
Views
5
CrossRef citations to date
0
Altmetric
Review

Targeted proteomics using immunoblotting technique for studying dysregulation of ion transporters in renal disorders

Carolyn A Ecelbarger Georgetown University, Department of Medicine, Box 571412, Washington DC, WA 20057-1412. [email protected]
Pages 219-227 | Published online: 09 Jan 2014

Reference

  • Lander ES, Linton LM, Birren B etal. Initial sequencing and analysis of the human genome. Nature 409,860–921 (2001).
  • Venter JC, Adams MD, Myers EW etal. The sequence of the human genome. Science 291,1304–1351 (2001).
  • Anderson N, Anderson N. Proteome and proteomics: new technologies, new concepts and new words. Electrophoresis 19, 1853–1861 (1998).
  • Nagele E, Vollmer M, Horth E Improved 2D nano-LC/MS for proteomics applications: a comparative analysis using yeast proteome. I Biomol. Tech. 15, 134–143 (2004).
  • Nagele E, Vollmer M, Horth E Two-dimensional nano-liquid chromatography-mass spectrometry system for applications in proteomics. Chromatogr. A 1009,197–205 (2003).
  • Pierce WM, Cai J. Applications of mass spectrometry in proteomics. Contrib. Nephrol. 141,40–58 (2004).
  • Cutillas P, Burlingame A, Unwin R. Proteomic strategies and their application in studies of renal function. News Physiol. Sc]. 19,114–119 (2004).
  • Bachhawat-Sikder K, Kodadek T. Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands. J. Am. Chem. Soc. 125,9550–9551 (2003).
  • Hoffert JD, van Balkom BW, Chou CL, Knepper MA. Application of difference gel electrophoresis to the identification of inner medullary collecting duct proteins. Am. J. Physiol. Renal Physiol. 286, F170—F179 (2004).
  • van Balkom BW, Hoffert JD, Chou CL, Knepper MA. Proteomic analysis of long-term vasopressin action in the inner medullary collecting duct of the Brattleboro rat. Am. J. Physiol. Renal Physiol. 286, F216—F224 (2004).
  • Chou CL, DiGiovanni SR, Luther A, Lolait SJ, Knepper MA. Oxytocin as an antidiuretic hormone. II. Role of V2 vasopressin receptor. Am. J. Physiol. 269, F78—F85 (1995).
  • DiGiovanni SR, Nielsen S, Christensen El, Knepper MA. Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat. Proc. Natl Acad. Sc]. USA 91,8984–8988 (1994).
  • Ecelbarger CA, Terris J, Frindt G etal. Aquaporin-3 water channel localization and regulation in rat kidney. Am. J. Physiol. 269, F663—F672 (1995).
  • Lingrel JB. Na, K-ATPase: isoform structure, function and expression. Bioenerg. Biomembr. 24,263-270 (1992).
  • Shull GE, Greeb J, Lingrel JB. Molecular cloning of three distinct forms of the Na+,K+-ATPase a-subunit from rat brain. Biochemistry Nom). 25,8125–8132 (1986).
  • Biemesderfer D, Pizzonia J, Abu-Alfa A et al. NHE3: a Na+/H+ exchanger isoform of renal brush border. Am. J. Physiol. 265, F736—F742 (1993).
  • Aronson PS. Mechanisms of active H+ secretion in the proximal tubule. Am. J. Physiol. 245, F647—F659 (1983).
  • Orlowski J, Kandasamy RA, Shull GE. Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. J Biol. Chem. 267, 9331–9339 (1992).
  • Biber J, Murer H, Forster I. The renal Type II Na+/phosphate cotransporter. Bioenerg. Biomembr. 30,187–194 (1998).
  • Magagnin S, Werner A, Markovich D et al. Expression cloning of human and rat renal cortex Na/Pi cotransport. Proc. Natl Acad. Sc]. USA 90,5979–5983 (1993).
  • Nielsen S, Smith BL, Christensen El, Knepper MA, Agre E CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J Cell Biol. 120,371–383 (1993).
  • Kaplan MR, Mount DB, Delpire E. Molecular mechanisms of NaC1 cotransport. Ann. Rev Physiol. 58, 649–668 (1996).
  • Gamba G, Miyanoshita A, Lombardi M et al. Molecular cloning, primary structure and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J. Biol. Chem. 269,17713–17722 (1994).
  • Garty H, Palmer LG. Epithelial sodium channels: function, structure and regulation. Physiol. Rev 77,359–396 (1997).
  • Canessa CM, Horisberger JD, Rossier BC. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361,467–470 (1993).
  • Canessa CM, Schild L, Buell G et al. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 367,463–467 (1994).
  • Dijkink L, Hartog A, van Os CH, Bindels RJ. The epithelial sodium channel (ENaC) is intracellularly located as a tetramer. Pflugers Arch. 444,549–555 (2002).
  • Nielsen S, DiGiovanni SR, Christensen El, Knepper MA, Harris HW. Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc. Natl Acad. Sc]. USA 90, 11663–11667 (1993).
  • Terris J, Ecelbarger CA, Marples D, Knepper MA, Nielsen S. Distribution of aquaporin-4 water channel expression within rat kidney. Am. J. Physiol. 269, F775—F785 (1995).
  • Song J, Knepper MA, Verbalis JG, Ecelbarger CA. Increased renal ENaC subunit and sodium transporter abundances in streptozotocin-induced Type 1 diabetes. Am. J Physiol. Renal Physiol. 285, F1125—F1137 (2003).
  • Masilamani S, Kim GH, Mitchell C, Wade JB, Knepper MA. Aldosterone-mediated regulation of ENaC 13 and y subunit proteins in rat kidney. J Clin. Invest. 104, R19—R23 (1999).
  • Kim GH, Ecelbarger C, Knepper MA, Packer RK. Regulation of thick ascending limb ion transporter abundance in response to altered acid/base intake. J Am. Soc. Nephrol. 10,935–942 (1999).
  • Kim GH, Ecelbarger CA, Mitchell C, Packer RK, Wade JB, Knepper MA. Vasopressin increases Na-K-2C1 cotransporter expression in thick ascending limb of Henle's loop. Am. J. Physiol. 276, F96—F103 (1999).
  • Terris J, Ecelbarger CA, Nielsen S, Knepper MA. Long-term regulation of four renal aquaporins in rats. Am. J. Physiol.271, F414—F422 (1996).
  • Fernandez-Llama P, Andrews P, Ecelbarger CA, Nielsen S, Knepper MA. Concentrating defect in experimental nephrotic syndrone: altered expression of aquaporins and thick ascending limb Na* transporters. Kidney Int. 54,170–179 (1998).
  • Kim GH, Masilamani S, Turner R, Mitchell C, Wade JB, Knepper MA. The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein. Proc. Natl Acad. Sci. USA 95,14552–14557 (1998).
  • Kim GH, Martin SW Fernandez-Llama P, Masilamani S, Packer RK, Knepper MA. Long-term regulation of renal Na-dependent cotransporters and ENaC: response to altered acid-base intake. Am. J. Physiol. Renal Physiol. 279, F459—F467 (2000).
  • Brooks HL, Allred AJ, Beutler KT, Coffman TM, Knepper MA. Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II Type la receptor knockout mice. Hypertension 39,470–473 (2002).
  • Nielsen J, Kwon TH, Masilamani S et al. Sodium transporter abundance profiling in kidney: effect of spironolactone. Am. J. Physiol. Renal Physiol. 283, F923—F933 (2002).
  • Kim SW Wang W Nielsen J et al. Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats. Am. J Physiol. Renal Physiol. 286(5), F922—F935 (2004).
  • Bickel CA, Knepper MA, Verbalis JG, Ecelbarger CA. Dysregulation of renal salt and water transport proteins in diabetic Zucker rats. Kidney Int. 61,2099–2110 (2002).
  • Na KY, Oh YK, Han JS et al. Upregulation of Na+ transporter abundances in response to chronic thiazide or loop diuretic treatment in rats. Am. J. Physiol. Renal Physiol. 284, F133—F143 (2003).
  • Thongboonkerd V, Klein JB. Proteomics and diabetic nephropathy. Contrib. Nephrol. 141,142–154 (2004).
  • Thongboonkerd V, McLeish K, Pierce W Epstein P, Klein J. Proteomic analysis of a hypoinsulinemic diabetic nephropathy. J. Am. Soc. Nephrol.(Suppl.), 102A-121A (2002).
  • Epstein PN, Overbeek PA, Means AR. Calmodulin-induced early-onset diabetes in transgenic mice. Ce1158, 1067–1073 (1989).
  • Umenishi F, Summer SN, Cadnapaphornchai M, Schrier RW. Comparison of three methods to quantify urinary aquaporin-2 protein. Kidney Int. 62,2288–2293 (2002).
  • McKee JA, Kumar S, Ecelbarger CA, Fernandez-Llama P, Terris J, Knepper MA. Detection of Na(+) transporter proteins in urine. J. Arn. Soc. Nephrol. 11,2128-2132 (2000).
  • Pedersen RS, Bentzen H, Bech JN, Pedersen EB. Effect of an acute oral ibuprofen intake on urinary aquaporin-2 excretion in healthy humans. Scand. j Clin. Lab. Invest. 61,631–640 (2001).
  • Takagi J, Otake K, Nakao N, Takashashi M, Hirooka Y. Urinary excretion of aquaporin-2 and inappropriate secretion of vasopressin in hyponatremic patients after cerebral infarction. Horm. Metab. Res. 35,62–66 (2003).
  • Ivarsen P, Frokiaer J, Aagaard NK et al. Increased urinary excretion of aquaporin-2 in patients with liver cirrhosis. Gut 52, 1194-1199 (2003).
  • Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ. Urinary proteomics of renal Fanconi syndrome. Contrib. Nephrol. 141,155–169 (2004).
  • Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ. Detection and analysis of urinary peptides by on-line liquid chromatography and mass spectrometry: application to patients with renal Fanconi syndrome. Clin. Sci. (Lond.) 104,483–490 (2003).
  • Pang JX, Ginanni N, Dongre AR, Hefta SA, Opitek GJ. Biomarker discovery in urine by proteomics. j Proteome Res. 1, 161–169 (2002).
  • Kaiser T, Kamal H, Rank A etal. Proteomics applied to the clinical follow-up of patients after allogeneic hematopoietic stem cell transplantation. Blood (2004).
  • Rogers MA, Clarke P, Noble J et al. Proteomic profiling of urinary proteins in renal cancer by surface enhanced laser desorption ionization and neural-network analysis: identification of key issues affecting potential clinical utility. Cancer Res. 63,6971–6983 (2003).
  • Bergeron M, Gougoux A, Noel J, Parent L. The renal Fanconi syndrome. In: The Metabolic Basis of Inherited Disease, Eighth edition. Scriver C, Sly W, Valle D, Vogelstein B, Childs B (Eds), McGraw-Hill, NY, USA, 5023–5038 (2001).
  • Klein J, Thongboonkerd V. Overview of proteomics. In: Proteomics in Nephrology Thongboonkerd V, Klein JB, Karger AG, Basel, Switzerland, 1–10 (2004).

Websites

  • The National Human Genome Research Institute www.genome.gov (Viewed July 2004)
  • Beyond Genome 2004 www.beyondgenome.com (Viewed July 2004)
  • NHLBI Proteomics Initiative www.nhlbi.nih.gov/resources/medres/ proteomics (Viewed July 2004)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.