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Expert Review of Proteomics Volume 13, 2016 - Issue 1

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Review

Molecular histology of arteries: mass spectrometry imaging as a novel ex vivo tool to investigate atherosclerosis

Marta Martin-LorenzoDepartment of Immunology, IIS-Fundacion Jimenez Diaz, UAM, Madrid, Spain

Gloria Alvarez-LlamasDepartment of Immunology, IIS-Fundacion Jimenez Diaz, UAM, Madrid, SpainCorrespondence[email protected]

Liam A. McDonnellCenter for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands

Fernando VivancoDepartment of Immunology, IIS-Fundacion Jimenez Diaz, UAM, Madrid, Spain;Department of Biochemistry and Molecular Biology I, UCM, Madrid, Spain

Pages 69-81 | Published online: 04 Dec 2015

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https://doi.org/10.1586/14789450.2016.1116944
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Molecular histology of arteries: mass spectrometry imaging as a novel ex vivo tool to investigate atherosclerosis

References

• A good introductory review for starting experiments in MSI field.

• Metabolites analysis by MSI from FFPE tissues.

•• The first application of MALDI-MSI to investigate protein changes in arterial atherosclerotic tissue.

•• A prognostic signature of gastric cancer was identified by MALDI MSI and further validated by IHC.

•• An update on atherosclerosis development and plaque vulnerability.

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Molecular histology of arteries: mass spectrometry imaging as a novel ex vivo tool to investigate atherosclerosis

References

• A good introductory review for starting experiments in MSI field.

• Metabolites analysis by MSI from FFPE tissues.

•• The first application of MALDI-MSI to investigate protein changes in arterial atherosclerotic tissue.

•• A prognostic signature of gastric cancer was identified by MALDI MSI and further validated by IHC.

•• An update on atherosclerosis development and plaque vulnerability.

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