734
Views
56
CrossRef citations to date
0
Altmetric
Reviews

Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis

, , , , , & show all

References

  • McGrath J, Saha S, Chant D, Welham J. Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev 2008;30:67-76
  • Wong AH, Van Tol HH. Schizophrenia: from phenomenology to neurobiology. Neurosci Biobehav Rev 2003;27(3):269-306
  • Andreasen NC. Symptoms, signs, and diagnosis of schizophrenia. Lancet 1995;346(8973):477-81
  • Bensenor IM, Brunoni AR, Pilan LA, et al. Cardiovascular risk factors in patients with first-episode psychosis in Sao Paulo, Brazil. Gen Hosp Psychiatry 2012;34(3):268-75
  • Brown S, Kim M, Mitchell C, Inskip H. Twenty-five year mortality of a community cohort with schizophrenia. Br J Psychiatry 2010;196(2):116-21
  • Leucht S, Cipriani A, Spineli L, et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet 2013;382(9896):951-62
  • Elkis H. Treatment-resistant schizophrenia. Psychiatr Clin North Am 2007;30(3):511-33
  • Brunoni AR, Kobuti Ferreira LR, Gallucci-Neto J, et al. Lithium as a treatment of clozapine-induced neutropenia: a case report. Prog Neuropsychopharmacol Biol Psychiatry 2008;32(8):2006-7
  • Kreyenbuhl J, Buchanan RW, Dickerson FB, Dixon LB. The Schizophrenia Patient Outcomes Research Team (PORT): updated treatment recommendations 2009. Schizophr Bull 2010;36(1):94-103
  • Hasan A, Falkai P, Wobrock T, et al. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, part 1: update 2012 on the acute treatment of schizophrenia and the management of treatment resistance. World J Biol Psychiatry 2012;13(5):318-78
  • Slotema CW, Blom JD, van Lutterveld R, et al. Review of the efficacy of transcranial magnetic stimulation for auditory verbal hallucinations. Biol Psychiatry 2013; Epub ahead of print
  • Shi C, Yu X, Cheung EF, et al. Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: a meta-analysis. Psychiatry Res 2014;215(3):505-13
  • Kuo MF, Paulus W, Nitsche MA. Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases. Neuroimage 2014;85 Pt 3:948-60
  • Nitsche MA, Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol 2000;527(Pt 3):633-9
  • Rahman A, Reato D, Arlotti M, et al. Cellular effects of acute direct current stimulation: somatic and synaptic terminal effects. J Physiol 2013;591(Pt 10):2563-78
  • Batsikadze G, Moliadze V, Paulus W, et al. Partially non-linear stimulation intensity-dependent effects of direct current stimulation on motor cortex excitability in humans. J Physiol 2013;591(Pt 7):1987-2000
  • Datta A, Bansal V, Diaz J, et al. Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad. Brain Stimul 2009;2(4):201-7
  • Radman T, Ramos RL, Brumberg JC, Bikson M. Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimul 009;2(4):215-28. 228 e211-213
  • Purpura DP, McMurtry JG. Intracellular activities and evoked potential changes during polarization of motor cortex. J Neurophysiol 1965;28:166-85
  • Nitsche MA, Jaussi W, Liebetanz D, et al. Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology 2004;29(8):1573-8
  • Nitsche MA, Fricke K, Henschke U, et al. Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol 2003;553(Pt 1):293-301
  • Fritsch B, Reis J, Martinowich K, et al. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron 2010;66(2):198-204
  • Favalli G, Li J, Belmonte-de-Abreu P, et al. The role of BDNF in the pathophysiology and treatment of schizophrenia. J Psychiatr Res 2012;46(1):1-11
  • Hasan A, Falkai P, Wobrock T. Transcranial brain stimulation in schizophrenia: targeting cortical excitability, connectivity and plasticity. Curr Med Chem 2013;20(3):405-13
  • Brunoni AR, Valiengo L, Baccaro A, et al. The Sertraline versus Electrical Current Therapy for Treating Depression Clinical Study: results from a factorial, randomized, controlled trial. JAMA Psychiatry 2013;70(4):383-91
  • Brunoni AR, Ferrucci R, Bortolomasi M, et al. Interactions Between Transcranial Direct Current Stimulation (tDCS) and Pharmacological Interventions in the Major Depressive Episode: findings from a naturalistic study. Eur Psychiatry 2013;28(6):356-61
  • Priori A, Hallett M, Rothwell JC. Repetitive transcranial magnetic stimulation or transcranial direct current stimulation? Brain Stimul 2009;2(4):241-5
  • Ahdab R, Ayache SS, Brugieres P, et al. Comparison of "standard" and "navigated" procedures of TMS coil positioning over motor, premotor and prefrontal targets in patients with chronic pain and depression. Neurophysiol Clin 2010;40(1):27-36
  • Westin GG, Bassi BD, Lisanby SH, Luber B. Determination of motor threshold using visual observation overestimates transcranial magnetic stimulation dosage: safety implications. Clin Neurophysiol 2014;125(1):142-7
  • Brunoni AR, Amadera J, Berbel B, et al. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int J Neuropsychopharmacol 2011;14(8):1133-45
  • Rossi S, Hallett M, Rossini PM, Pascual-Leone A. Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol 2009;120(12):2008-39
  • Palm U, Hasan A, Keeser D, et al. Transcranial random noise stimulation for the treatment of negative symptoms in schizophrenia. Schizophr Res 2013;146(1-3):372-3
  • Villamar MF, Wivatvongvana P, Patumanond J, et al. Focal modulation of the primary motor cortex in fibromyalgia using 4x1-ring high-definition transcranial direct current stimulation (HD-tDCS): immediate and delayed analgesic effects of cathodal and anodal stimulation. J Pain 2013;14(4):371-83
  • Wagner TA, Zahn M, Grodzinsky AJ, Pascual-Leone A. Three-dimensional head model simulation of transcranial magnetic stimulation. IEEE Trans Biomed Eng 2004;51(9):1586-98
  • Gabriel C, Gabriel S, Corthout E. The dielectric properties of biological tissues: I. Literature survey. Phys Med Biol 1996;41(11):2231-49
  • Mattai A, Miller R, Weisinger B, et al. Tolerability of transcranial direct current stimulation in childhood-onset schizophrenia. Brain Stimul 2011;4(4):275-80
  • Brunelin J, Mondino M, Gassab L, et al. Examining Transcranial Direct-Current Stimulation (tDCS) as a Treatment for Hallucinations in Schizophrenia. Am J Psychiatry 2012;169(7):719-24
  • Nawani H, Bose A, Agarwal SM, et al. Modulation of Corollary Discharge Dysfunction in Schizophrenia by tDCS: preliminary Evidence. Brain Stimul 2014; Epub ahead of print
  • Homan P, Kindler J, Federspiel A, et al. Muting the voice: a case of arterial spin labeling-monitored transcranial direct current stimulation treatment of auditory verbal hallucinations. Am J Psychiatry 2011;168(8):853-4
  • Rakesh G, Shivakumar V, Subramaniam A, et al. Monotherapy with tDCS for Schizophrenia: a case report. Brain Stimul 2013;6(4):708-9
  • Nawani H, Kalmady SV, Bose A, et al. Neural Basis of tDCS effects on auditory verbal hallucinations in schizophrenia: a case report evidence for cortical neuroplasticity modulation. J ECT 2014;30(1):e2-4
  • Shivakumar V, Bose A, Rakesh G, et al. Rapid improvement of auditory verbal hallucinations in schizophrenia after add-on treatment with transcranial direct-current stimulation. J ECT 2013;29(3):e43-4
  • Shiozawa P, da Silva ME, Cordeiro Q, et al. Transcranial direct current stimulation (tDCS) for catatonic schizophrenia: a case study. Schizophr Res 2013;146(1-3):374-5
  • Shiozawa P, da Silva ME, Cordeiro Q, et al. Transcranial Direct Current Stimulation (tDCS) for the treatment of persistent visual and auditory hallucinations in schizophrenia: a case study. Brain Stimul 2013;6(5):831-3
  • Palm U, Keeser D, Blautzik J, et al. Prefrontal transcranial direct current stimulation (tDCS) changes negative symptoms and functional connectivity MRI (fcMRI) in a single case of treatment-resistant schizophrenia. Schizophr Res 2013;150(2-3):583-5
  • Andrade C. Once- to twice-daily, 3-year domiciliary maintenance transcranial direct current stimulation for severe, disabling, clozapine-refractory continuous auditory hallucinations in schizophrenia. J ECT 2013;74(11):e1054-8
  • Bikson M, Inoue M, Akiyama H, et al. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. J Physiol 2004;557(Pt 1):175-90
  • Busatto GF. Structural and Functional Neuroimaging Studies in Major Depressive Disorder With Psychotic Features: a Critical Review. Schizophr Bull 2013;39(4):776-86
  • van Haren NE, Schnack HG, Cahn W, et al. Changes in cortical thickness during the course of illness in schizophrenia. Arch Gen Psychiatry 2011;68(9):871-80
  • Ellison-Wright I, Bullmore E. Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophr Res 2009;108(1-3):3-10
  • Potkin SG, Turner JA, Brown GG, et al. Working memory and DLPFC inefficiency in schizophrenia: the FBIRN study. Schizophr Bull 2009;35(1):19-31
  • Kuhn S, Gallinat J. Resting-state brain activity in schizophrenia and major depression: a quantitative meta-analysis. Schizophr Bull 2013;39(2):358-65
  • Andreasen NC, O'Leary DS, Flaum M, et al. Hypofrontality in schizophrenia: distributed dysfunctional circuits in neuroleptic-naive patients. Lancet 1997;349(9067):1730-4
  • Freitas C, Fregni F, Pascual-Leone A. Meta-analysis of the effects of repetitive transcranial magnetic stimulation (rTMS) on negative and positive symptoms in schizophrenia. Schizophr Res 2009;108(1-3):11-24
  • Dlabac-de Lange JJ, Knegtering R, Aleman A. Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: review and meta-analysis. J Clin Psychiatry 2010;71(4):411-18
  • Fregni F, Boggio PS, Nitsche M, et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res 2005;166(1):23-30
  • Oliveira JF, Zanao TA, Valiengo L, et al. Acute working memory improvement after tDCS in antidepressant-free patients with major depressive disorder. Neurosci Lett 2013;537:60-4
  • Barr MS, Farzan F, Rajji TK, et al. Can repetitive magnetic stimulation improve cognition in schizophrenia? Pilot data from a randomized controlled trial. Biol Psychiatry 2013;73(6):510-17
  • Prikryl R. Repetitive transcranial magnetic stimulation and treatment of negative symptoms of schizophrenia. Neuro Endocrinol Lett 2011;32(2):121-6
  • Demeulemeester M, Amad A, Bubrovszky M, et al. What is the real effect of 1-Hz repetitive transcranial magnetic stimulation on hallucinations? Controlling for publication bias in neuromodulation trials. Biol Psychiatry 2012;71(6):e15-16
  • Suddath RL, Casanova MF, Goldberg TE, et al. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. Am J Psychiatry 1989;146(4):464-72
  • Dierks T, Linden DE, Jandl M, et al. Activation of Heschl's gyrus during auditory hallucinations. Neuron 1999;22(3):615-21
  • Homan P, Kindler J, Hubl D, Dierks T. Auditory verbal hallucinations: imaging, analysis, and intervention. Eur Arch Psychiatry Clin Neurosci 2012;262(Suppl 2):S91-5
  • Olabi B, Ellison-Wright I, McIntosh AM, et al. Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies. Biol Psychiatry 2011;70(1):88-96
  • Bracha HS, Wolkowitz OM, Lohr JB, et al. High prevalence of visual hallucinations in research subjects with chronic schizophrenia. Am J Psychiatry 1989;146(4):526-8
  • Manford M, Andermann F. Complex visual hallucinations. Clinical and neurobiological insights. Brain 1998;121(Pt 10):1819-40
  • Muller PA, Pascual-Leone A, Rotenberg A. Safety and tolerability of repetitive transcranial magnetic stimulation in patients with pathologic positive sensory phenomena: a review of literature. Brain Stimul 2012;5(3):320-9. e327
  • Merabet LB, Kobayashi M, Barton J, Pascual-Leone A. Suppression of complex visual hallucinatory experiences by occipital transcranial magnetic stimulation: a case report. Neurocase 2003;9(5):436-40
  • Meppelink AM, de Jong BM, van der Hoeven JH, van Laar T. Lasting visual hallucinations in visual deprivation; fMRI correlates and the influence of rTMS. J Neurol Neurosurg Psychiatry 2010;81(11):1295-6
  • Northoff G, Kotter R, Baumgart F, et al. Orbitofrontal cortical dysfunction in akinetic catatonia: a functional magnetic resonance imaging study during negative emotional stimulation. Schizophr Bull 2004;30(2):405-27
  • Northoff G, Steinke R, Nagel DC, et al. Right lower prefronto-parietal cortical dysfunction in akinetic catatonia: a combined study of neuropsychology and regional cerebral blood flow. Psychol Med 2000;30(3):583-96
  • Scheuerecker J, Ufer S, Kapernick M, et al. Cerebral network deficits in post-acute catatonic schizophrenic patients measured by fMRI. J Psychiatr Res 2009;43(6):607-14
  • Richter A, Grimm S, Northoff G. Lorazepam modulates orbitofrontal signal changes during emotional processing in catatonia. Hum Psychopharmacol 2010;25(1):55-62
  • Saba G, Rocamora JF, Kalalou K, et al. Catatonia and transcranial magnetic stimulation. Am J Psychiatry 2002;159(10):1794
  • Kate MP, Raju D, Vishwanathan V, et al. Successful treatment of refractory organic catatonic disorder with repetitive transcranial magnetic stimulation (rTMS) therapy. J Neuropsychiatry Clin Neurosci 2011;23(3):E2-3
  • Grisaru N, Chudakov B, Yaroslavsky Y, Belmaker RH. Catatonia treated with transcranial magnetic stimulation. Am J Psychiatry 1998;155(11):1630
  • Poreisz C, Boros K, Antal A, Paulus W. Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients. Brain Res Bull 2007;72(4-6):208-14
  • Stagg CJ, Nitsche MA. Physiological basis of transcranial direct current stimulation. Neuroscientist 2011;17(1):37-53
  • Jacobson L, Koslowsky M, Lavidor M. tDCS polarity effects in motor and cognitive domains: a meta-analytical review. Exp Brain Res 2012;216(1):1-10
  • Busatto GF, Kerwin RW. Schizophrenia, psychosis, and the basal ganglia. Psychiatr Clin North Am 1997;20(4):897-910
  • Brunoni AR, Nitsche MA, Bolognini N, et al. Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions. Brain Stimul 2012;5(3):175-95
  • Tu PC, Lee YC, Chen YS, et al. Schizophrenia and the brain's control network: aberrant within- and between-network connectivity of the frontoparietal network in schizophrenia. Schizophr Res 2013;147(2-3):339-47
  • Tu PC, Hsieh JC, Li CT, et al. Cortico-striatal disconnection within the cingulo-opercular network in schizophrenia revealed by intrinsic functional connectivity analysis: a resting fMRI study. Neuroimage 2012;59(1):238-47
  • Rogasch NC, Daskalakis ZJ, Fitzgerald PB. Cortical Inhibition, Excitation, and Connectivity in Schizophrenia: a Review of Insights From Transcranial Magnetic Stimulation. Schizophr Bull 2013; Epub ahead of print
  • Creutzfeld D, Fromm GH, Kapp H. Influence of transcortical d-c currents on cortical neuronal activity. Exp Neural 1962;5:436-52
  • Jefferys JG. Influence of electric fields on the excitability of granule cells in guinea-pig hippocampal slices. J Physiol 1981;319:143-52
  • Bikson M, Radman T, Datta A. Rational modulation of neuronal processing with applied electric fields. Conf Proc IEEE Eng Med Biol Soc 2006;1:1616-19
  • Basser PJ, Roth BJ. New currents in electrical stimulation of excitable tissues. Annu Rev Biomed Eng 2000;2:377-97
  • Di Lazzaro V, Manganelli F, Dileone M, et al. The effects of prolonged cathodal direct current stimulation on the excitatory and inhibitory circuits of the ipsilateral and contralateral motor cortex. J Neural Transm 2012;119(12):1499-506
  • Hasan A, Nitsche MA, Herrmann M, et al. Impaired long-term depression in schizophrenia: a cathodal tDCS pilot study. Brain Stimul 2012;5(4):475-83
  • Hasan A, Nitsche MA, Rein B, et al. Dysfunctional long-term potentiation-like plasticity in schizophrenia revealed by transcranial direct current stimulation. Behav Brain Res 2011;224(1):15-22

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.