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Onyx®: a unique neuroembolic agent

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Pages 705-715 | Published online: 09 Jan 2014

References

  • Stapf C, Mohr JP, Pile-Spellman J, Solomon RA, Sacco RL, Connolly ES. Epidemiology and natural history of arteriovenous malformations. Neurosurg. Focus11(5), 1–5 (2005).
  • Pawlikowska L, Tran MN, Achrol AS et al. Polymorphisms in transforming growth factor-(β)-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. Stroke36, 2278–2280 (2005).
  • Fults D, Kelly DL Jr. Natural history of arteriovenous malformations of the brain: a clinical study. Neurosurgery15(5), 658–662 (1984).
  • Ondra SL, Troupp H, George ED, Schwab K. The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment. J. Neurosurg.73, 387–391 (1990).
  • Frizzel RT, Fisher WS III. Cure, morbidity, and mortality associated with embolization of brain arteriovenous malformations: a review of 1246 patients in 32 series over a 35-year period. Neurosurgery37(6), 1031–1039 (1995)
  • Ledezma CJ, Hoh BL, Carter BS, Pryor JC, Putman CM, Ogilvy CS. Complications of cerebral arteriovenous malformation embolization: multivariate analysis of predictive factors. Neurosurgery58(4), 602–611 (2006).
  • Spetzler RF, Wilson CB, Weinstein P et al. Normal perfusion pressure breatkthrough theory. Clin. Neurosurg.25, 651–672 (1978).
  • Connors JJ III, Wojac JC. Fundamentals of interventional neuroradiology: tools of the trade. Chapter 1. In: Interventional Neuroradiology– Strategies and Practical Techniques. Connors JJ, Wojac JC (Eds). W.B. Saunders, PA, USA, 1–43 (1999).
  • Kerber CW, Wong W. Liquid acrylic adhesive agents in interventional neuroradiology. Neurosurg. Clin. N. Am.11(1), 85–99 (2000).
  • Taki W, Yonekawa Y, Iwata H et al. A new liquid material for embolization of arteriovenous malformations. AJNR11, 163–168 (1990).
  • Terada T, Nakamura Y, Nakai K et al. Embolization of arteriovenous malformations with peripheral aneurysms using ethylene vinyl alcohol copolymer. J. Neurosurg.75, 655–660 (1991).
  • Chaloupka JC, Vinuela F, Vinters HV, Robert J. Technical feasibility and histopathologic studies of ethylene vinyl copolymer (EVAL) using a swine endovascular embolization model. AJNR15, 1107–1115 (1994).
  • Yamashita K, Taki W, Iwata H et al. Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures. AJNR15, 1103–1105 (1994).
  • Murayama Y, Vinuela F, Ulhoa A et al. Nonadhesive liquid embolic agent for cerebral arteriovenous malformations: preliminary histopathological studies in swine rete mirabile. Neurosurgery43(5), 1164–1175 (1998).
  • Chaloupka JC, Huddle DC, Alderman J et al. A reexamination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model. AJNR20, 401–410 (1999).
  • Pamuk AG, Saatci I, Cekirge HS, Aypur U. A contribution to the controversy over dimethyl sulfoxide toxicity: anesthesia monitoring results in patients treated with Onyx embolization for intracranial aneurysms. Neuroradiology47, 380–386 (2005).
  • Saatci I, Cekirge S, Ciceri EFM et al. CT and MRI imaging findings and their implication in the follow-up of patients with intracranial aneurysms treated with endosaccular occlusion with Onyx. AJNR24, 567–578 (2003).
  • Akin ED, Perkins E, Ross IB. Surgical handling characteristics of an ethylene vinyl alcohol copolymer compared with N-butyl cyanoacrylate used for embolization of vessels in an arteriovenous malformation resection model in swine. J. Neurosurg.98, 366–370 (2003).
  • Howington JU, Kerber CW, Hopkins LN. Liquid embolic agents in the treatment of intracranial arteriovenous malformations. Neurosurg. Clin. N. Am.16, 355–363 (2005).
  • Jahan R, Murayama Y, Gobin YP et al. Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients. Neurosurgery48(5), 984–997 (2001).
  • Higashida R. Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients [comment]. Neurosurgery48, 995 (2001).
  • Lagares A, Lobarto RD, Ricoy JR, Campollo J. Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients [comment]. Neurosurgery51, 1525–1526 (2002).
  • Molyneux AJ, Cekirge S, Saatci I, Gail G. Cerebral Aneurysm Multicenter European Onyx (CAMEO) trial: results of a prospective observational study in 20 European centers. AJNR25, 39–51 (2004).
  • Cekirge HS, Saatci I, Ozturk MH et al. Late angiographic and clinical follow-up results of 100 consecutive aneurysms treated with Onyx reconstruction: largest single-center experience. Neuroradiology48(2), 113–126 (2006).
  • Murayama Y, Nien YL, Duckwiler G et al. Guglielmi detachable coil embolization of cerebral aneurysms: 11 years’ experience. J. Neurosurg.98, 959–966 (2003).
  • Murayama Y, Vinuela F, Tateshima S, Vinuela F Jr, Akiba Y. Endovascular treatment of experimental aneurysms by use of a combination of liquid embolic agents and protective devices. AJNR21, 1726–1735 (2000).
  • Warakaulle DR, Aviv RI, Niemann D et al. Embolisation of spinal dural arteriovenous fistulae with Onyx. Neuroradiology45, 110–112 (2003).
  • Arat A, Cekirge S, Saatci I, Ozgen B. Transvenous injection of Onyx for casting of the cavernous sinus for the treatment of a carotid-cavernous fistula. Neuroradiology46, 1012–1015 (2004).
  • Suzuki S, Lee DW, Jahan R, Duckwiler GR, Vinuela F. Transvenous treatment of spontaneous dural carotid-cavernous fistulas using a combination of detachable coils and Onyx. AJNR27, 1346–1349 (2006).
  • Gobin YP, Murayama Y, Milanese K et al. Head and neck hypervascular lesions: embolization with ethylene vinyl alcohol copolymer – laboratory evaluation in swine and clinical evaluation in humans. Radiology221, 309–317 (2001).
  • Hamada J, Kai Y, Kazekawa K et al. A nonadhesive liquid embolic agent composed of ethylene vinyl alcohol copolymer and ethanol mixture for the treatment of cerebral arteriovenous malformations: experimental study. J. Neurosurg.97(4), 889–895 (2002).
  • Hamada J, Kai Y, Morioka K et al. A mixture of ethylene vinyl alcohol copolymer and ethanol yielding a nonadhesive liquid embolic agent to treat cerebral arteriovenous malformations: initial clinical experience. J. Neurosurg.97(4), 881–888 (2002).

Patent

  • Evans S, Jones ML, Greff R. Embolizing compositions. US patent.5695480 (1997).

Website

  • Microtherapeutics Inc. product website www.microtherapeutics.com/products/index.php

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