Effects of perinatal overfeeding on mechanisms controlling food intake and body weight homeostasis

References

• Friedman JM. A war on obesity, not the obese. Science299(5608), 856–858 (2003).
   PubMed Web of Science ®Google Scholar
• Flier JS. Obesity wars: molecular progress confronts an expanding epidemic. Cell 116(2), 337–350 (2004).
   PubMed Web of Science ®Google Scholar
• Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia35(7), 595–601 (1992).
   PubMed Web of Science ®Google Scholar
• Hales CN, Barker DJ. The thrifty phenotype hypothesis. Br. Med. Bull.60, 5–20 (2001).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Heidrich I, Gotz F, Rohde W, Dorner G. Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeeding. Exp. Clin. Endocrinol.99(3), 154–158 (1992).
   PubMedGoogle Scholar
• Ozanne SE, Hales CN. Lifespan: catch-up growth and obesity in male mice. Nature427(6973), 411–412 (2004).
   PubMed Web of Science ®Google Scholar
• McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol. Rev.85(2), 571–633 (2005).
   PubMed Web of Science ®Google Scholar
• Plagemann A. Perinatal nutrition and hormone-dependent programming of food intake. Horm. Res.65(Suppl 3), 83–89 (2006).
   PubMedGoogle Scholar
• Lucas A. Programming by early nutrition in man. Ciba Found.Symp.156, 38–50 (1991).
   PubMedGoogle Scholar
• McCance RB. Food growth and time. Lancet2, 271–272 (1962).
   PubMedGoogle Scholar
• López M, Seoane LM, Tovar S et al. A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat. Diabetologia48(1), 140–148 (2005).
   PubMedGoogle Scholar
• López M, Tovar S, Vázquez MJ et al. Perinatal overfeeding in rats results in increased levels of plasma leptin but unchanged cerebrospinal leptin in adulthood. Int. J. Obes. Relat. Metab. Disord. (2006)(In Press).
   Google Scholar
• Lucas A. Programming by early nutrition: an experimental approach. J. Nutr.128(2 Suppl.), 401S–406S (1998).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Harder T, Rake A et al. Perinatal elevation of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurons, and syndrome x-like alterations in adulthood of neonatally overfed rats. Brain Res.836(1–2), 146–155 (1999).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Harder T, Rake A et al. Observations on the orexigenic hypothalamic neuropeptide Y-system in neonatally overfed weanling rats. J. Neuroendocrinol.11(7), 541–546 (1999).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Li Y, Plagemann A. Hypothalamic ventromedial and arcuate neurons of normal and postnatally overnourished rats differ in their responses to melanin-concentrating hormone. Regul. Pept.108(2–3), 103–111 (2002).
   PubMedGoogle Scholar
• Kalra SP, Dube MG, Pu S et al. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev.20(1), 68–100 (1999).
   PubMed Web of Science ®Google Scholar
• Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature404(6778), 661–671 (2000).
   PubMed Web of Science ®Google Scholar
• Meister B. Control of food intake via leptin receptors in the hypothalamus. Vitam. Horm.59, 265–304 (2000).
   PubMedGoogle Scholar
• Boullu-Ciocca S, Paulmyer-Lacroix O, Fina F et al. Expression of the mRNAs coding for the glucocorticoid receptor isoforms in obesity. Obes. Res.11(8), 925–929 (2003).
   PubMedGoogle Scholar
• Young JB. Effects of litter size on sympathetic activity in young adult rats. Am. J. Physiol. Regul. Integr. Comp. Physiol.282(4), R1113–R1121 (2002).
   Google Scholar
• Meaney MJ, Diorio J, Francis D et al. Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress. Dev. Neurosci.18(1–2), 49–72 (1996).
   PubMed Web of Science ®Google Scholar
• Seckl JR, Meaney MJ. Glucocorticoid programming. Ann. NY Acad. Sci.1032, 63–84 (2004).
   PubMed Web of Science ®Google Scholar
• Angelbeck JH, DuBrul EF. The effect of neonatal testosterone on specific male and female patterns of phosphorylated cytosolic proteins in the rat preoptic-hypothalamus, cortex and amygdala. Brain Res.264(2), 277–283 (1983).
   PubMed Web of Science ®Google Scholar
• Garcia-Segura LM, Baetens D, Naftolin F. Sex differences and maturational changes in arcuate nucleus neuronal plasma membrane organization. Brain Res.351(1), 146–149 (1985).
   PubMedGoogle Scholar
• Garcia-Segura LM, Baetens D, Naftolin F. Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats. Brain Res.366(1–2), 131–136 (1986).
   PubMedGoogle Scholar
• Naftolin F, Mor G, Horvath TL et al. Synaptic remodeling in the arcuate nucleus during the estrous cycle is induced by estrogen and precedes the preovulatory gonadotropin surge. Endocrinology137(12), 5576–5580 (1996).
   PubMed Web of Science ®Google Scholar
• Horvath TL, Diano S. Opinion: the floating blueprint of hypothalamic feeding circuits. Nat. Rev. Neurosci.5(8), 662–667 (2004).
   PubMedGoogle Scholar
• Plagemann A, Rake A, Harder T et al. Reduction of cholecystokinin-8S-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling rats. Neurosci. Lett.258(1), 13–16 (1998).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Harder T, Rake A et al. Increased number of galanin-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling rats. Brain Res.818(1), 160–163 (1999).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Rittel F, Waas T, Harder T, Rohde W. Cholecystokinin-8S levels in discrete hypothalamic nuclei of weanling rats exposed to maternal protein malnutrition. Regul. Pept.85(2–3), 109–113 (1999).
   PubMedGoogle Scholar
• Plagemann A, Harder T, Rake A et al. Hypothalamic nuclei are malformed in weanling offspring of low protein malnourished rat dams. J. Nutr.130(10), 2582–2589 (2000).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Waas T, Harder T et al. Hypothalamic neuropeptide Y levels in weaning offspring of low-protein malnourished mother rats. Neuropeptides34(1), 1–6 (2000).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Harder T, Melchior K et al. Elevation of hypothalamic neuropeptide Y neurons in adult offspring of diabetic mother rats. Neuroreport10(15), 3211–3216 (1999).
   PubMed Web of Science ®Google Scholar
• Heidel E, Plagemann A, Davidowa H. Increased response to NPY of hypothalamic VMN neurons in postnatally overfed juvenile rats. Neuroreport10(9), 1827–1831 (1999).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Li Y, Plagemann A. Differential response to NPY of PVH and dopamine-responsive VMH neurons in overweight rats. Neuroreport13(12), 1523–1527 (2002).
   PubMedGoogle Scholar
• Li Y, Plagemann A, Davidowa H. Increased inhibition by agouti-related peptide of ventromedial hypothalamic neurons in rats overweight due to early postnatal overfeeding. Neurosci. Lett.330(1), 33–36 (2002).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Li Y, Plagemann A. Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats. Eur. J. Neurosci.18(3), 613–621 (2003).
   PubMed Web of Science ®Google Scholar
• Kozak R, Richy S, Beck B. Persistent alterations in neuropeptide Y release in the paraventricular nucleus of rats subjected to dietary manipulation during early life. Eur. J. Neurosci.21(10), 2887–2892 (2005).
   PubMedGoogle Scholar
• Davidowa H, Heidel E, Plagemann A. Differential involvement of dopamine D1 and D2 receptors and inhibition by dopamine of hypothalamic VMN neurons in early postnatally overfed juvenile rats. Nutr. Neurosci.5(1), 27–36 (2002).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Li Y, Plagemann A. Altered neuronal responses to feeding-relevant peptides as sign of developmental plasticity in the hypothalamic regulatory system of body weight. Zh. Vyssh. Nerv. Deiat. Im IP Pavlova53(5), 663–670 (2003).
   PubMed Web of Science ®Google Scholar
• Cowley MA, Smart JL, Rubinstein M et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature411(6836), 480–484 (2001).
   PubMed Web of Science ®Google Scholar
• Boullu-Ciocca S, Dutour A, Guillaume V et al. Postnatal diet-induced obesity in rats upregulates systemic and adipose tissue glucocorticoid metabolism during development and in adulthood: its relationship with the metabolic syndrome. Diabetes54(1), 197–203 (2005).
   PubMed Web of Science ®Google Scholar
• Pinto S, Roseberry AG, Liu H et al. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science304(5667), 110–115 (2004).
   PubMed Web of Science ®Google Scholar
• Bouret SG, Draper SJ, Simerly RB. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science304(5667), 108–110 (2004).
   PubMed Web of Science ®Google Scholar
• Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D Jr. Insulin in the brain: a hormonal regulator of energy balance. Endocr. Rev.13(3), 387–414 (1992).
   PubMed Web of Science ®Google Scholar
• Nataf V, Monier S. Effect of insulin and insulin-like growth factor I on the expression of the catecholaminergic phenotype by neural crest cells. Brain Res. Dev. Brain Res.69(1), 59–66 (1992).
   PubMedGoogle Scholar
• Woods SC, Seeley RJ, Baskin DG, Schwartz MW. Insulin and the blood-brain barrier. Curr. Pharm. Des9(10), 795–800 (2003).
   PubMed Web of Science ®Google Scholar
• Plagemann A, Harder T, Rake A et al. Morphological alterations of hypothalamic nuclei due to intrahypothalamic hyperinsulinism in newborn rats. Int. J. Dev. Neurosci.17(1), 37–44 (1999).
   PubMed Web of Science ®Google Scholar
• Wang J, Leibowitz KL. Central insulin inhibits hypothalamic galanin and neuropeptide Y gene expression and peptide release in intact rats. Brain Res.777(1–2), 231–236 (1997).
   PubMedGoogle Scholar
• Schwartz MW, Sipols AJ, Marks JL et al. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology130(6), 3608–3616 (1992).
   PubMed Web of Science ®Google Scholar
• Dorner G, Plagemann A. Perinatal hyperinsulinism as possible predisposing factor for diabetes mellitus, obesity and enhanced cardiovascular risk in later life. Horm. Metab. Res.26(5), 213–221 (1994).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Plagemann A. Inhibition by insulin of hypothalamic VMH neurons in rats overweight due to postnatal overfeeding. Neuroreport12, 3201–3204 (2001).
   PubMedGoogle Scholar
• Zhang Y, Proenca R, Maffei M et al. Positional cloning of the mouse obese gene and its human homologue. Nature372(6505), 425–432 (1994).
   PubMed Web of Science ®Google Scholar
• Casanueva FF, Dieguez C. Neuroendocrine regulation and actions of leptin. Front Neuroendocrinol.20(4), 317–363 (1999).
   PubMed Web of Science ®Google Scholar
• Ahima RS, Flier JS. Leptin. Annu. Rev. Physiol.62, 413–437 (2000).
   PubMed Web of Science ®Google Scholar
• Schmidt I, Fritz A, Scholch C et al. The effect of leptin treatment on the development of obesity in overfed suckling Wistar rats. Int. J. Obes. Relat. Metab. Disord.8, 1168–1174 (2001).
   Google Scholar
• Schmidt I, Schoelch C, Ziska T et al. Interaction of genetic and environmental programming of the leptin system and of obesity disposition. Physiol. Genomics3(2), 113–120 (2000).
   PubMedGoogle Scholar
• Davidowa H, Plagemann A. Decreased inhibition by leptin of hypothalamic arcuate neurons in neonatally overfed young rats. Neuroreport11(12), 2795–2798 (2000).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Plagemann A. Different responses of ventromedial hypothalamic neurons to leptin in normal and early postnatal overfed rats. Neurosci. Lett.293, 21–24 (2000).
   PubMed Web of Science ®Google Scholar
• García MC, López M, Gualillo O et al. Hypothalamic levels of NPY, MCH, and prepro-orexin mRNA during pregnancy and lactation in the rat: role of prolactin. FASEB J.17(11), 1392–1400 (2003).
   PubMedGoogle Scholar
• Seeber RM, Smith JT, Waddell BJ. Plasma leptin-binding activity and hypothalamic leptin receptor expression during pregnancy and lactation in the rat. Biol. Reprod.66(6), 1762–1767 (2002).
   PubMedGoogle Scholar
• Van Heek M, Compton DS, France CF et al. Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J. Clin. Invest.99(3), 385–390 (1997).
   PubMed Web of Science ®Google Scholar
• Burguera B, Couce ME, Curran GL et al. Obesity is associated with a decreased leptin transport across the blood–brain barrier in rats. Diabetes49(7), 1219–1223 (2000).
   PubMed Web of Science ®Google Scholar
• Furuhata Y, Kagaya R, Hirabayashi K et al. Development of obesity in transgenic rats with low circulating growth hormone levels: involvement of leptin resistance. Eur. J. Endocrinol.143(4), 535–541 (2000).
   PubMedGoogle Scholar
• Banks WA, Farrell CL. Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible. Am. J. Physiol. Endocrinol. Metab.285(1), E10–E15 (2003).
   PubMed Web of Science ®Google Scholar
• Tronche F, Kellendonk C, Reichardt HM, Schutz G. Genetic dissection of glucocorticoid receptor function in mice. Curr. Opin. Genet. Dev.8, 532–538 (1998).
   PubMed Web of Science ®Google Scholar
• Freedman MR, Horwitz BA, Stern JS. Effect of adrenalectomy and glucocorticoid replacement on development of obesity. Am. J. Physiol.250(4 Pt 2), R595–R607 (1986).
   PubMedGoogle Scholar
• Zakrzewska KE, Cusin I, Sainsbury A, Rohner-Jeanrenaud F, Jeanrenaud B. Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance. Diabetes46(4), 717–719 (1997).
   PubMed Web of Science ®Google Scholar
• Masuzaki H, Paterson J, Shinyama H et al. A transgenic model of visceral obesity and the metabolic syndrome. Science294(5549), 2166–2170 (2001).
   PubMed Web of Science ®Google Scholar
• Velkoska E, Cole TJ, Morris MJ. Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers. Am. J. Physiol. Endocrinol. Metab.288(6), E1236–E1243 (2005).
   PubMed Web of Science ®Google Scholar
• Kojima M, Hosoda H, Date Y et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature402(6762), 656–660 (1999).
   PubMed Web of Science ®Google Scholar
• Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature407(6806), 908–913 (2000).
   PubMed Web of Science ®Google Scholar
• Seoane LM, López M, Tovar S et al. Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Endocrinology144(2), 544–551 (2003).
   PubMed Web of Science ®Google Scholar
• Nogueiras R, Tovar S, Mitchell SE et al. Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin. Diabetes53(10), 2552–2558 (2004).
   PubMedGoogle Scholar
• Sun Y, Ahmed S, Smith RG. Deletion of ghrelin impairs neither growth nor appetite. Mol. Cell. Biol.23(22), 7973–7981 (2003).
   PubMed Web of Science ®Google Scholar
• Wortley KE, Del Rincon JP, Murray JD et al. Absence of ghrelin protects against early-onset obesity. J. Clin. Invest.115(12), 3573–3578 (2005).
   PubMed Web of Science ®Google Scholar
• Zigman JM, Nakano Y, Coppari R et al. Mice lacking ghrelin receptors resist the development of diet-induced obesity. J. Clin. Invest.115(12), 3564–3572 (2005).
   PubMed Web of Science ®Google Scholar
• Grove KL, Cowley MA. Is ghrelin a signal for the development of metabolic systems? J. Clin. Invest.115(12), 3393–3397 (2005).
   PubMed Web of Science ®Google Scholar
• Davidowa H, Ziska T, Plagemann A. Arcuate neurons of overweight rats differ in their responses to amylin from controls. Neuroreport15(18), 2801–2805 (2004).
   PubMedGoogle Scholar
• Stanley S, Wynne K, McGowan B, Bloom S. Hormonal regulation of food intake. Physiol. Rev.85(4), 1131–1158 (2005).
   PubMed Web of Science ®Google Scholar
• Batterham RL, Cowley MA, Small CJ et al. Gut hormone PYY(3–36) physiologically inhibits food intake. Nature418(6898), 650–654 (2002).
   PubMed Web of Science ®Google Scholar
• Challis BG, Pinnock SB, Coll AP et al. Acute effects of PYY3–36 on food intake and hypothalamic neuropeptide expression in the mouse. Biochem. Biophys. Res. Commun.311(4), 915–919 (2003).
   PubMed Web of Science ®Google Scholar
• Tschop M, Castaneda TR, Joost HG et al. Physiology: does gut hormone PYY3–36 decrease food intake in rodents? Nature430(6996), 1 (2004).
   PubMedGoogle Scholar
• Coll AP, Challis BG, O’Rahilly S. Peptide YY3–36 and satiety: clarity or confusion? Endocrinology145(6), 2582–2584 (2004).
   PubMedGoogle Scholar
• Halatchev IG, Cone RD. Peripheral administration of PYY3–36 produces conditioned taste aversion in mice. Cell Metab.1(3), 159–168 (2005).
   PubMed Web of Science ®Google Scholar
• Broberger C, Landry M, Wong H, Walsh JN, Hokfelt T. Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus. Neuroendocrinology66(6), 393–408 (1997).
   PubMed Web of Science ®Google Scholar
• Hales CN, Barker DJ, Clark PM et al. Fetal and infant growth and impaired glucose tolerance at age 64. Br. Med. J.303(6809), 1019–1022 (1991).
   PubMed Web of Science ®Google Scholar
• Ozanne SE, Hales CN. Early programming of glucose-insulin metabolism. Trends Endocrinol. Metab.13(9), 368–373 (2002).
   PubMed Web of Science ®Google Scholar
• Susser M, Stein Z. Timing in prenatal nutrition: a reprise of the Dutch Famine Study. Nutr. Rev.52(3), 84–94 (1994).
   PubMed Web of Science ®Google Scholar
• Roseboom TJ, van der Meulen JH, Ravelli AC et al. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview. Mol. Cell. Endocrinol.185(1–2), 93–98 (2001).
   PubMed Web of Science ®Google Scholar
• Gillman MW, Rifas-Shiman S, Berkey CS, Field AE, Colditz GA. Maternal gestational diabetes, birth weight, and adolescent obesity. Pediatrics111(3), e221-e226 (2003).
   Web of Science ®Google Scholar
• Jaquet D, Leger J, Tabone MD, Czernichow P, Levy-Marchal C. High serum leptin concentrations during catch-up growth of children born with intrauterine growth retardation. J. Clin. Endocrinol. Metab.84(6), 1949–1953 (1999).
   PubMed Web of Science ®Google Scholar
• Phillips DI, Fall CH, Cooper C et al. Size at birth and plasma leptin concentrations in adult life. Int. J. Obes. Relat. Metab. Disord.23(10), 1025–1029 (1999).
   PubMedGoogle Scholar
• Singhal A, Farooqi IS, O’Rahilly S et al. Early nutrition and leptin concentrations in later life. Am. J. Clin. Nutr.75(6), 993–999 (2002).
   PubMedGoogle Scholar
• Plagemann A. Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity. Physiol. Behav. (2005).
   PubMedGoogle Scholar