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Review

Control of colon cancer development and progression by selected estrogen receptor modulators

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Pages 503-511 | Published online: 10 Jan 2014

References

  • Mandalà M, Mosconi S, Quadri A et al. Neoadjuvant chemotherapy for patients with liver metastasis from colorectal cancer. Expert Rev. Anticancer. Ther.7(6), 887–897 (2007).
  • Bishop JM. Molecular themes in oncogenesis. Cell64(2), 235–248 (1991).
  • Ponder BA. Molecular genetics of cancer. BMJ304(6836), 1234–1236 (1992).
  • Vogelstein B, Fearon ER, Hamilton SR et al. Genetic alterations during colorectal tumor development. N. Engl. J. Med.319(9), 525–532 (1988).
  • Fearon ER, Cho KR, Nigro JM et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science247(4938), 49–56 (1990).
  • Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature386(6627), 761–763 (1997).
  • Bodmer WF, Bailey CJ, Bodmer J et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature328(6131), 614–616 (1987).
  • Al-Tassan N, Chmiel NH, Maynard J et al. Inherited variants of MYH associated with somatic G:C --> T:A mutation in colorectal tumors. Nat. Genet.30(2), 227–332 (2002).
  • Peltomaki P, Aaltonene L, Sistonen P et al. Genetic mapping of a locus predisponing to human colorectal cancer. Science260(5109), 810–812 (1993).
  • Quehenberger F, Vasen HFA, van Houwelingen HC. Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment. J. Med. Genet.42(6), 491–496 (2005).
  • Vasen HFA, Stormorken A, Menko FH et al. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families. J. Clin. Oncol.19, 4074–4080 (2001).
  • Aarnio M, Mecklin JP, Aaltonen LA et al. Lifetime risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome. Int. J. Cancer64, 430–433 (1995).
  • Aarnio M, Sankila R, Pukkala E et al. Cancer risk in mutation carriers of DNA mismatch-repair genes. Int. J. Cancer81, 214–218 (1999).
  • Parc Y, Boisson C, Thomas G et al. Cancer risk in 348 French MSH2 or MLH1 gene carriers. J. Med. Genet.40, 208–213 (2003).
  • Watson P, Lynch HT. Cancer risk in mismatch repair gene mutation carriers. Fam. Cancer1, 57–60 (2001).
  • Hendriks YM, de Jong AE, Morreau H et al. Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians. CA Cancer J. Clin.56(4), 213–225 (2006).
  • McMichael AJ, Potter JD. Do intrinsic sex differences in lower alimentary tract physiology influence the sex-specific risks of bowel cancer and other biliary and intestinal diseases? Am. J. Epidemiol.118(5), 620–627 (1983).
  • Weiss NS, Daling JR, Chow WH. Incidence of cancer of the large bowel in women in relation to reproductive and hormonal factors. J. Natl Cancer Inst.67(1), 57–60 (1981).
  • Grodstein F, Martinez ME, Platz EA et al. Postmenopausal hormone use and risk for colorectal cancer and adenoma. Ann. Intern. Med.128(9), 705–712 (1998).
  • Grodstein F, Newcomb PA, Stampfer MJ. Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis. Am. J. Med.106(5), 574–582 (1999).
  • Chlebowski RT, Wactawaski-Wende J, Ritenbaugh C et al. Estrogens plus progestin and colorectal cancer in postmenopausal women. N. Engl. J. Med.350(10), 991–1004 (2004).
  • Mandelson MT, Miglioretti D, Newcomb PA, Harrison R, Potter JD. Hormone replacement therapy in relation to survival in women diagnosed with colon cancer. Cancer Causes Control14(10), 979–984 (2003).
  • Slattery ML, Potter JD, Curtin K et al. Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer. Cancer Res.61(1), 126–130 (2001).
  • Colditz GA. Relationship between estrogen levels, use of hormone replacement therapy, and breast cancer. J. Natl Cancer Inst.90(11), 814–823 (1998).
  • Koehler KF, Helguero LA, Haldosén LA, Warner M, Gustafsson JA. Reflections on the discovery and significance of estrogen receptor β. Endocr. Rev.26(3), 465–478 (2005).
  • Chambliss KL, Yuhanna IS, Anderson RG, Mendelsohn ME, Shaul PW. ERβ has nongenomic action in caveolae. Mol. Endocrinol.16(5), 938–946 (2002).
  • Razandi M, Pedram A, Merchenthaler I, Greene GL, Levin ER. Plasma membrane estrogen receptors exist and functions as dimers. Mol. Endocrinol.18(12), 2854–2865 (2004).
  • Acconcia F, Kumar R. Signaling regulation of genomic and nongenomic functions of estrogen receptors. Cancer Lett.238(1), 1–14 (2006).
  • Nilsson S, Mäkelä S, Treuter E et al. Mechanisms of estrogen action. Physiol. Rev.81(4), 1535–1565 (2001).
  • Pettersson K, Gustafsson JA. Role of estrogen receptor β in estrogen action. Ann. Rev. Physiol.63, 165–192 (2001).
  • Couse JF, Korach KS. Estrogen receptor null mice. What have we learned and where will they lead us? Endocr. Rev.20(3), 358–417 (1999).
  • Xie LQ, Yu JP, Luo HS. Expression of estrogen receptor β in human colorectal cancer. World J. Gastroenterol.10(2), 214–217 (2004).
  • Konstantinopoulos PA, Kominea A, Vandoros G et al. Oestrogen receptor β (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour’s dedifferentiation. Eur. J. Cancer39(9), 1251–1258 (2003).
  • Jassam N, Bell SM, Speirs V, Quirke P. Loss of expression of estrogen receptor β in colon cancer and its association with Duke’s staging. Oncol. Rep.14(1), 17–21 (2005).
  • Fiorelli G, Picariello L, Martineti V, Tonelli F, Brandi ML. Functional estrogen receptor β in colon cancer cells. Biochem. Biophys. Res. Commun.261(2), 521–527 (1999).
  • Arai N, Strom A, Rafter JJ, Gustafsson JA. Estrogen receptor β mRNA in colon cancer cells: growth effects of estrogen and genistein. Biochem. Biophys. Res. Commun.270(2), 425–431 (2000).
  • Campbell-Thompson M, Lynch IJ, Bhardwaj B. Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer. Cancer Res.61(2), 632–640 (2001).
  • Nakayama Y, Sakamoto H, Satoh K, Yamamoto T. Tamoxifen and gonadal steroids inhibit colon cancer growth in association with inhibition of thymidylate synthase, survivin and telomerase expression through estrogen receptor β mediated system. Cancer Lett.161(1), 63–71 (2000).
  • Nojima D, Li LC, Dharia A et al. CpG hypermethylation of the promoter region inactivates the estrogen receptor-β gene in patients with prostate carcinoma. Cancer92(8), 2076–2083 (2001).
  • Zhao C, Lam EW, Sunters A et al. Expression of estrogen receptor β isoform in normal breast epithelial cells and breast cancer: regulation by methylation. Oncogene22(48), 7600–7606 (2003).
  • Zhang X, Leung YK, Ho SM. AP-2 regulates the transcription of estrogen receptor (ER)-β by acting through a methylation hotspot of the 0N promoter in prostate cancer cells. Oncogene26(52), 7346–7354 (2007).
  • Liu MM, Albanese C, Anderson CM et al. Opposing action of estrogen receptors alpha and β on cyclin D1 gene expression. J. Biol. Chem.277(27), 24353–24360 (2002).
  • Pettersson K, Delaunay F, Gustafsson JA. Estrogen receptor β acts as a dominant regulator of estrogen signaling. Oncogene19(43), 4970–4978 (2000).
  • Weihua Z, Makela S, Andersson LC et al. A role for estrogen receptor β in the regulation of growth of the ventral prostate. Proc. Natl Acad. Sci. USA98(11), 6330–6335 (2001).
  • Paech K, Webb P, Kuiper GG et al. Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science277(5331), 1508–1510 (1997).
  • Martineti V, Picariello L, Tognarini I et al. ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components. Endocr. Relat. Cancer12(2), 455–469 (2005).
  • Wada-Hiraike O, Imamov O, Hiraike H et al. Role of estrogen receptor β in colonic epithelium. Proc. Natl Acad. Sci. USA103(8), 2959–2964 (2006).
  • Narayan S, Rajakumar G, Prouix H, Singh P. Estradiol is trophic for colon cancer in mice: effect on ornithine decarboxylase and c-myc messenger RNA. Gastroenterology103(6), 1823–1832 (1992).
  • Singh S, Paraskeva C, Gallimore PH, Sheppard MC, Langman MJ. Differential growth response to oestrogen of premalignant and malignant colonic cell lines. Anti Cancer Res.14(3A), 1037–1041 (1994).
  • Fiorelli G, Picariello L, Martineti V, Tonelli F, Brandi ML. Functional estrogen receptor β in colon cancer cells. Biochem. Biophys. Res. Commun.261(2), 521–527 (1999).
  • Weyant MJ, Carothers AM, Mahmoud NN et al. Reciprocal expression of ERα and ERβ is associated with estrogen-mediated modulation of intestinal tumorigenesis. Cancer Res.61(6), 2547–2551 (2001).
  • Hsu HH, Cheng SF, Wu CC et al. Apoptotic effects of over-expressed estrogen receptor-β on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner. China J. Physiol.49(2), 110–116 (2006).
  • Lee H, Jiang F, Wang Q et al. MEKK1 activation of human estrogen receptor β and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells. Mol. Endocrinol.14(11), 1882–1896 (2000).
  • Driggers PH, Segars JH, Rubino DM. The protooncoprotein Brx activates estrogen receptor β by a p38 mitogen-activated protein kinase pathway. J. Biol. Chem.276(50), 46792–46797 (2001).
  • Chen SL, Chang YJ, Wu YH, Lin KH. Mitogenactivated protein kinases potentiate thyroid hormone receptor transcriptional activity by stabilizing its protein. Endocrinology144(4), 1407–1419 (2003).
  • Lee H, Bai W. Regulation of estrogen receptor nuclear export by ligand-induced and p38-mediated receptor phosphorylation. Mol. Cell. Biol.22(16), 5835–5845 (2002).
  • Wilpart M, Mainguet P, Maskens A, Roberfroid M. Mutagenicity of 1,2-dimethylhydrazine towards Salmonella typhimurium, co-mutagenic effect of secondary biliary acids. Carcinogenesis4(1), 45–48 (1983).
  • Allende HD, Ona FV, Davis HT. Gallbladder disease: risk factor for colorectal carcinoma? J. Clin. Gastroenterol.6(1), 51–55 (1984).
  • McMichael AJ, Potter JD. Reproduction, endogenous and exogenous sex hormones, and colon cancer: a review and hypothesis. J. Natl Cancer Inst.65(6), 1201–1207 (1980).
  • Terry PD, Miller AB, Rohan TE. Obesity and colorectal cancer risk in women. Gut51(2), 191–194 (2002).
  • Powell DR, Suwanichkul A, Cubbage ML, DePaolis LA, Snuggs MB, Lee PD. Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J. Biol. Chem.266(28), 18868–18876 (1991).
  • Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J. Nutr.131(Suppl. 11), S3109–S3120 (2001).
  • Ettinger B, Black DM, Mitlak BH et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. JAMA282(7), 637–645 (1999).
  • Kanis JA, Johnell O, Black DM et al. Effect of raloxifene on the risk of new vertebral fracture in postmenopausal women with osteopenia or osteoporosis: a reanalysis of the Multiple Outcomes of Raloxifene Evaluation trial. Bone33(3), 293–300 (2003).
  • Siris ES, Harris ST, Eastell R et al. Continuing Outcomes Relevant to Evista (CORE) Investigators. Skeletal effects of raloxifene after 8 years: results from the continuing outcomes relevant to Evista (CORE) study. J. Bone Miner. Res.20(9), 1514–1524 (2005).
  • Cauley JA, Norton L, Lippman ME et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res. Treat.65(2), 125–134 (2001).
  • Cummings SR, Eckert S, Krueger KA et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA281(23), 2189–2197 (1999).
  • Martino S, Cauley JA, Barrett-Connor E et al. Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J. Natl Cancer Inst.96(23), 1751–1761 (2004).
  • Vogel VG, Costantino JP, Wickerham DL et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA295(23), 2727–2741 (2006).
  • Cummings SR, Duong T, Kenyon E, Cauley JA, Whitehead M, Krueger KA; Multiple Outcomes of Raloxifene Evaluation (MORE) Trial. Serum estradiol level and risk of breast cancer during treatment with raloxifene. JAMA287(2), 216–220 (2002).
  • Barrett-Connor E, Cauley JA, Kulkarni PM, Sashegyi A, Cox DA, Geiger MJ. Risk-benefit profile for raloxifene: 4-year data From the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial. J. Bone Miner. Res.19(8), 1270–1275 (2004).
  • Dickler MN, Norton L. The MORE trial: multiple outcomes for raloxifene evaluation – breast cancer as a secondary end point: implications for prevention. Ann. NY Acad. Sci.949, 134–142 (2001).
  • Barrett-Connor E, Mosca L, Collins P et al. Raloxifene Use for The Heart (RUTH) trial investigators. Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N. Engl. J. Med.355(2), 125–137 (2006).
  • Picariello L, Fiorelli G, Martineti V et al. Growth response of colon cancer cell lines to selective estrogen receptor modulators. Anti Cancer Res.23(3B), 2419–2424 (2003).
  • Kuiper GG, Lemmen JG, Carlsson B et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology139(10), 4252–4263 (1998).
  • Herold C, Ganslmayer M, Ocker M et al. Overadditive anti-proliferative and pro-apoptotic effects of a combination therapy on colorectal carcinoma cells. Int. J. Oncol.23(3), 751–756 (2003).
  • Walsh JME, Cheung AM, Yang D, Litwack S, Grady D. Raloxifene and colorectal cancer. J. Womens Health (Larchmt).14(4), 299–305 (2005).
  • Yin F, Shi YQ, Chen CP et al. Expression of cDNA fragment encoding MGr1-Ag1 detected by MDR related antibody MGr1 in gastric cancer. Shi Jie Hua Ren Xiao Hua Za Zhi11, 18–21 (2003).
  • Uchiyama-Kokubu N, Watanabe T. Establishment and characterization of adriamycin-resistant human colorectal adenocarcinoma HCT-15 cell lines with multidrug resistance. Anticancer Drugs12(9), 769–779 (2001).
  • Wang BL, Zhai HY, Chen BY et al. Clinical relationship between MDR1 gene and gallbladder cancer. Hepatobiliary Pancreat. Dis. Int.3(2), 296–299 (2004).
  • Lorke DE, Kruger M, Buchert R, Bohuslavizki KH, Clausen M, Schumacher U. In vitro and in vivo tracer characteristics of an established multidrug-resistant human colon cancer cell line. J. Nucl. Med.42(4), 646–654 (2001).
  • Shen LZ, Hua YB, Yu XM et al. Tamoxifen can reverse multidrug resistance of colorectal carcinoma in vivo. World J. Gastroenterol.11(7), 1060–1064 (2005).
  • Hamilton G, Cosentini EP, Teleky B et al. The multidrug-resistance modifiers verapamil, cyclosporine A and tamoxifen induce an intracellular acidification in colon carcinoma cell lines In vitro. Anti Cancer Res.13(6A), 2059–2063 (1993).

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