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Drug Profile

Novel intravitreal fluocinolone acetonide implant in the treatment of chronic noninfectious posterior uveitis

Pages 33-44 | Published online: 09 Jan 2014

References

  • Nussenblatt RB, Whitcup SM, Palestine AG. Uveitis: Fundamentals and Clinical Practice. (2nd Ed.). Mosby, MO, USA (1996).
  • Foster CS, Vitale AT. Treatment of uveitis: overview. In: Diagnosis and Treatment of Uveitis. (1st Ed.). WB Saunders Company, NY, USA, 150 (2002).
  • Durrani OM, Tehrani NN, Marr JE, Moradi P, Stavrou P, Murray PI. Degree, duration, and causes of visual loss in uveitis. Br. J. Ophthalmol.88, 1159–1162 (2004).
  • Gritz DC, Wong IG. Incidence and prevalence of uveitis in northern California; the northern California epidemiology of uveitis study. Ophthalmology111(3), 491–500 (2004).
  • Dandona L, Dandona R, John RK et al. Population based assessment of uveitis in an urban population in southern India. Br. J. Ophthalmol.84, 706–709 (2000).
  • Becker MD, Smith JR, Max R, Feihn C. Management of sight-threatening uveitis: new therapeutic options. Drugs65(4), 497–519 (2005).
  • Rothova A. Corticosteroids in uveitis. Ophthalmol. Clin. North Am.15(3), 389–394 (2002).
  • Jabs DA, Rosenbaum JT, Foster CS et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am. J. Ophthalmol.130, 492–513 (2000).
  • Geroski DH, Edelhauser HF. Drug delivery for posterior segment eye disease. Invest. Ophthalmol. Vis. Sci.41(5), 961–964 (2000).
  • Jager RD, Aiello LP, Patel SC, Cunningham ET Jr. Risks of intravitreous injection: a comprehensive review. Retina24, 676–698 (2004).
  • Thompson JT. Cataract formation and other complications of intravitreal triamcinolone for macular edema. Am. J. Ophthalmol.141, 629–637 (2006).
  • Quiram PA, Gonzales CR, Schwartz SD. Severe steroid-induced glaucoma following intravitreal injection of triamcinolone acetonide. Am. J. Ophthalmol.141, 580–582 (2006).
  • Yang CS, Chen MJ, Chou CK, Hsu WM. Refractory severe ocular hypertension after intravitreal triamcinolone acetonide injection. Ophthalmologica219, 413–415 (2005).
  • Jonas JB, Spandau UH, Kamppeter BA et al. Follow-up after intravitreal triamcinolone acetonide for diabetic macular edema. Eur. J. Ophthalmol.16, 566–572 (2006).
  • Kok H, Lau C, Maycock N et al. Outcome of intravitreal triamcinolone in uveitis. Ophthalmology112, 1916 (2005).
  • Durrani K, Papaliodis GN, Foster CS. Pulse IV cyclophosphamide in ocular inflammatory disease: efficacy and short-term safety. Ophthalmology111(5), 960–965 (2004).
  • Goldstein DA, Fontanilla FA, Kaul S et al. Long-term follow-up of patients treated with short-term high-dose chlorambucil for sight-threatening ocular inflammation. Ophthalmology109(2), 370–377 (2002).
  • Sarwal MM, Yorgin PD, Alexander S et al. Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation. Transplantation72(1), 13–21 (2001).
  • American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines. Guidelines for the management of rheumatoid arthritis: 2002 update. Arthritis Rheum.46(2), 328–346 (2002).
  • Samson CM, Waheed N, Baltatzis S et al. Methotrexate therapy for chronic noninfectious uveitis: analysis of a case series of 160 patients. Ophthalmology108(6), 1134–1139 (2001).
  • Doycheva DG, Deuter CM, Stuebiger N, Biester S, Zierhut M. Mycophenolate mofetil in the treatment of uveitis in children. Br. J. Ophthalmol. doi:10.1136/bjo.2006.094698 (2006). (Epub ahead of print).
  • Lau CH, Comer M, Lightman S. Long-term efficacy of mycophenolate mofetil in the control of severe intraocular inflammation. Clin. Experiment. Ophthalmol.31(6), 487–491 (2003).
  • Siepmann K, Huber M, Stubiger N, Deuter C, Zierhut M. Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis: a retrospective analysis of 106 patients. Graefes Arch. Clin. Exp. Ophthalmol.244, 788–794 (2006).
  • Thorne JE, Jabs DA, Qazi FA, Nguyen QD, Kempen JH, Dunn JP. Mycophenolate mofetil therapy for inflammatory eye disease. Ophthalmology112, 1472–1477 (2005).
  • Nussenblatt RB, de Smet MD, Rubin B et al. A masked, randomized, dose-response study between cyclosporine A and G in the treatment of sight-threatening uveitis of noninfectious origin. Am. J. Ophthalmol.115, 583–591 (1993).
  • Hesselink DA, Baarsma GS, Kuijpers RW et al. Experience with cyclosporine in endogenous uveitis posterior. Transplant Proc.36(2), 372S–377S (2004).
  • Okada AA. Immunomodulatory therapy for ocular inflammatory disease: a basic manual and review of the literature. Ocular Immunol. Inflamm.13, 335–351 (2005).
  • Caspi RR. Th1 and Th2 responses in pathogenesis and regulation of experimental autoimmune uveoretinitis. Int. Rev. Immunol.21(2–3), 197–208 (2002).
  • Nussenblatt RB, Thompson DJ, Li Z et al. Humanized anti-interleukin-2 (IL-2) receptor α therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administration. J. Autoimmun.21(3), 283–293 (2003).
  • Papaliodis GN, Chu D, Foster CS. Treatment of ocular inflammatory disorders with daclizumab. Ophthalmology110(4), 786–789 (2003).
  • Church AC. Clinical advances in therapies targeting the interleukin-2 receptor. QJM96(2), 91–102 (2003).
  • Santos LM, Marcos MC, Gallardo GJM et al. Aqueous humor and serum tumor necrosis factor-α in clinical uveitis. Ophthalmic Res.33(5), 251–255 (2001).
  • Reiff A. Long-term outcome of etanercept therapy in children with treatment-refractory uveitis (letter). Arthritis Rheum.48(7), 2079–2080 (2003).
  • Etanercept Prescribing Information. Immunex Corp.; Amgen; Wyeth (2006).
  • Suhler EB, Smith JR, Wertheim MS et al. A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes. Arch. Ophthalmol.123, 903–912 (2005).
  • Infliximab Prescribing Information. Centocor, Inc., PA, USA (2006).
  • Murphy CC, Greiner K, Plskova J et al. Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis. Arch. Ophthalmol.122, 845–851 (2004).
  • Kim H, Robinson MR, Lizak MJ et al. Controlled drug release from an ocular implant: an evaluation using dynamic 3-dimensional magnetic resonance imaging. Invest. Ophthalmol. Vis. Sci.45(8), 2722–2731 (2004).
  • Kurz D, Ciulla TA. Novel approaches for retinal drug delivery. Ophthalmol. Clin. North Am.15(3), 405–410 (2002).
  • Retisert™ Prescribing Information, Bausch & Lomb, Inc. (2005).
  • Jaffe GJ, Yang CH, Guo H, Denny JP, Lima C, Ashton P. Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device. Invest. Ophthalmol. Vis. Sci.41(11), 3569–3575 (2000).
  • Driot JY, Novack GD, Rittenhouse KD, Milazzo C, Pearson PA. Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period. J. Ocul. Pharmacol. Therapeutics20(3), 269–275 (2004).
  • Jaffe GJ, McCallum RM, Branchaud B, Skalak C, Butuner Z, Ashton P. Long-term follow-up of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. Ophthalmology112, 1192–1198 (2005).
  • Jaffe GJ, Martin D, Callanan D, Pearson PA, Levy B, Comstock T. Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis. Ophthalmology113, 1019–1026 (2006).
  • Lim LL, Smith JR, Rosenbaum JT. Retisert: Bausch and Lomb/Control Delivery Systems. Curr. Opin. Invest. Drugs6(11), 1159–1167 (2005).
  • Fluocinolone acetonide ophthalmic – Bausch & Lomb: fluocinolone acetonide envision TD implant. Drugs RD6(2), 116–119 (2005).
  • Herbert HM, Viswanathan A, Jackson H, Lightman SL. Risk factors for elevated intraocular pressure in uveitis. J. Glaucoma13, 96–99 (2004).
  • Holekamp NM, Thomas MA, Pearson A. The safety profile of long-term, high-dose intraocular corticosteroid delivery. Am. J. Ophthalmol.139, 421–428 (2005).
  • Bucher RS, Hall E, Reed DM, Richards JE, Johnson MW, Zacks DN. Effect of intravitreal triamcinolone acetonide on susceptibility to experimental bacterial endophthalmitis and subsequent response to treatment. Arch. Ophthalmol.123(5), 649–653 (2005).

Websites

  • Oculex Pharmaceuticals, Inc. Oculex Pharmaceuticals begins Phase II clinical trial of Posurdex for persistent macular edema (2001). www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/10–29–2001/0001602952&EDATE
  • Roach L. Inside the eye: precision drug delivery. EyeNet, American Academy of Ophthalmology, January (2003) www.aao.org/aao/news/eyenet/feature1/ feature1_jan.htm
  • Allergan, Inc. Allergan’s investigational Posurdex technology demonstrates improvement in patients with macular edema (swelling of the retina) in Phase II clinical trial according to data presented at American Academy of Ophthalmology (2003) www.shareholder.com/agn/ReleaseDetail. cfm?ReleaseID=123213
  • Charters L. Dexamethasone implant treats persistent macular edema: Intravitreal bioerodable drug delivery system associated with significant visual improvement. Ophthalmology Times (2005) www.ophthalmologytimes.com/ ophthalmologytimes/article/articleDetail. jsp?id=186746
  • pSivida, Inc. Ophthalmology (2004) www.psivida.com/application/ Ophthalmologyasp
  • Data Safety Monitoring Board. Briefly: Alimera Sciences and Control Delivery Systems launch Phase III trial for DME. Review of Ophthalmology Online 5(42), 5 (2005) www.revophth.com/archive/newsletter/ ro_102405.htm
  • SurModics, Inc. I-vation sustained drug delivery system: intravitreal implant for drug delivery (2006) www.surmodics.com
  • Bausch and Lomb, Inc. website for Retisert implant. www.retisert.com
  • Bausch and Lomb, Inc. Bausch and Lomb and Control Delivery Systems announce results of first Phase III clinical trial of Envision TD ophthalmic implant for treatment of diabetic macula edema (2002) www.bausch.com

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