2
Views
0
CrossRef citations to date
0
Altmetric
Perspective

Arguments against preimplantation aneuploidy screening

&
Pages 115-118 | Published online: 10 Jan 2014

References

  • Kolibianakis E, Zikopoulos K, Verpoest W et al. Should we advise patients undergoing IVF to start a cycle leading to a day 3 or a day 5 transfer? Hum. Reprod.19, 2550–2554 (2004).
  • Papanikolaou E, D’Haeseleer E, Verheyen G et al. Live birth rate is significantly higher after blastocyst transfer than after cleavage-stage embryo transfer when at least four embryos are available on day 3. A randomized prospective study. Hum. Reprod.20, 3198–3203 (2005).
  • Staessen C, Platteau P, Van Assche E et al. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomised controlled trial. Hum. Reprod.19, 2849–2858 (2004).
  • Munné S. Chromosome abnormalities and their relationship to morphology and development of human embryos. Reprod. Biomed. Online12, 234–253 (2006).
  • Munné S, Lee A, Rosenwaks Z, Grifo J, Cohen J. Diagnosis of major chromosome aneuploidies in human preimplantation embryos. Hum. Reprod.8, 2185–2191 (1993).
  • Staessen C, Michiels A, Verpoest W, Van der Elst J, Liebaers I, Devroey P. Does PGS improve pregnancy rates in young patients with single embryo transfer. Hum. Reprod.22(Suppl. 1), I31–I33 (2007).
  • Gianaroli L, Magli C, Ferraretti A, Munné S. Preimplantation diagnosis for aneuploidies in patients undergoing in vitro fertilization with poor prognosis: identification of the categories for which it should be proposed. Fertil. Steril.72, 837–844 (1999).
  • Munné S, Sandalinas M, Escudero T et al. Improved implantation after preimplantation genetic diagnosis of aneuploidy. Reprod. Biomed. Online7, 91–97 (2003).
  • Munné S, Chen S, Fischer J et al. Preimplantation genetic diagnosis reduces pregnancy loss in women aged 35 years and older with a history of recurrent miscarriages. Fertil. Steril.84(2), 331–335 (2005).
  • Colls P, Escudo T, Cekleniak N, Sadowy S, Cohen J, Munné S. Increased efficiency of preimplantation genetic diagnosis for infertility using “no result rescue”. Fertil. Steril.88(1), 53–61 (2007).
  • Caglar GS, Asimakopoulos B, Nikolettos N, Diedrich K, Al-Hassani S. Preimplantation genetic diagnosis for aneuploidy screening in repeated implantation failure. Reprod. Biomed. Online10, 381–388 (2005).
  • Taranissi M, El-Toukhy T, Gorgy A, Verlinsky Y. Influence of maternal age on the outcome of PGD for aneuploidy screening in patients with recurrent implantation failure. Reprod. Biomed. Online10, 628–632 (2005).
  • Munné S, Magli C, Cohen J. Positive outcome after preimplantation diagnosis of aneuploidy in human embryos. Hum. Reprod.14, 2191–2199 (1999).
  • Munné S, Fischer J, Warner A, Chen S, Zouves C, Cohen J; The Referring Centers PGD Group. Preimplantation genetic diagnosis significantly reduces pregnancy loss in infertile couples: a multicenter study. Fertil. Steril.85(2), 326–332 (2006).
  • Garrisi J, Colls P, Ferry KM, Zheng X, Garrisi MG, Munné S. Effect of infertility, maternal age, and number of previous miscarriages on the outcome of preimplantation genetic diagnosis for idiopathic recurrent pregnancy loss. Fertil. Steril. DOI 10.1016/j.fertnstert.2008.05.056, (2008) (Epub ahead of print).
  • Viville S, Mollard R, Bach M, Falquet C, Gerlinger P, Warter S. Do morphological anomalies reflect chromosomal aneuploïdies? Hum. Reprod.15(12), 2563–2566 (2000).
  • Kahraman S, Sertyel S, Findikli N et al. Effect of PGD on implantation and ongoing pregnancy rates in cases with predominantly macrocephalic spermatozoa. Reprod. Biomed. Online9(1), 79–84 (2004).
  • Stevens J, Wale P, Surrey ES, Schoolcraft WB. Is aneuploidy screening for patients aged 35 or over beneficial? A prospective randomized trial. Fertil. Steril.82(Suppl. 2), 249 (2004).
  • Mastenbroek S, Twisk M, van Echten-Arends J. In vitro fertilization with preimplantation genetic screening. N. Engl. J. Med.357, 9–17 (2007).
  • Goossens V, De Rycke M, De Vos A et al. Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis. Hum. Reprod.23(3), 481–492 (2008).
  • Twisk M, Mastenbroeck S, van Wely M, Heineman MJ, Van der Veen F, Repping S. Preimplantation genetic screening for abnormal number of chromosomes (aneuploidies) in in vitro fertilization or intracytoplasmic sperm injection. Cochrane Database Syst. Rev.25(1), CD005291 (2006).
  • Munné S, Cohen J, Simpson JL. In vitro fertilization with preimplantation genetic screening. N. Engl. J. Med.357, 17 (2007).
  • Simpson JL, Bombard AT. Chromosomal abnormalities in spontaneous abortion: frequency, pathology and genetic counseling. In: Spontaneous Abortion. Edmonds K, Bennett MJ (Eds). Blackwell, London, UK (1987).
  • Vouillaire L, Slater H, Williamson R, Wilton L. Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization. Hum. Genet.106, 210–217 (2000).
  • Munné S, Weier H, Grifo J, Cohen J. Chromosome mosaicism in human embryos. Biol. Reprod.51, 373–379 (1994).
  • Baart E, Van Opstal D, Los F, Fauser B, Martini E. Fluorescence in situ hybridization analysis of two blastomeres from day 3 frozen-thawed embryos followed by analysis of the remaining embryo on day 5. Hum. Reprod.19, 685–693 (2004).
  • Coonen E, Derhaag J, Dumoulin J et al. Anaphase lagging mainly explains chromosomal mosaicism in human preimplantation embryo. Hum. Reprod.19, 316–324 (2004).
  • Magli MC, Gianaroli L, Ferraretti AP, Lappi M, Ruberti A, Farfalli V. Embryo morphology and development are dependent on the chromosomal complement. Fertil. Steril.87(3), 534–541 (2007).
  • Baart E, Martini E, van den Bergh I. Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF. Hum. Reprod.21, 223–233 (2006).
  • Munné S, Sandalinas M, Escudero T, Marquez C, Cohen J. Chromosome mosaicism in cleavage-stage human embyos: evidence of a maternal age effect. Reprod. Biomed. Online4, 223–232 (2002).
  • Los FJ, van Opstal D, van den Berg C. The development of cytogenetically normal, abnormal and mosaic embryos: a theoretical model. Hum. Reprod. Update10, 79–94 (2004).
  • Li M, DeUgarte CM, Surrey M, Danzer H, DeCherney A, Hill DL. Fluorescence in situ hybridization reanalysis of day-6 human blastocysts diagnosed with aneuploidy on day 3. Fertil. Steril.84, 1395–1400 (2005).
  • Pellestor F. The cytogenetic analysis of human zygotes and preimplantation embryos. Hum. Reprod. Update1, 581–585 (1995).
  • Munné S, Alikani M, Tomkin G, Grifo J, Cohen J. Embryo morphology, developmental rates and maternal age are correlated with chromosome abnormalities. Fertil. Steril.64, 382–391 (1995).
  • Sandalinas M, Sadowy S, Alikani M, Calderon G, Cohen J, Munné S. Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage. Hum. Reprod.16, 1954–1958 (2001).
  • Munné S, Gianaroli L, Tur-Kapsa I et al. Substandard application of preimplantation genetic screening may interfere with its clinical success. Fertil. Steril.88, 781–784 (2007).
  • Verlinsky Y, Cohen J, Nummé S et al. Over a decade of experience with preimplantation genetic diagnosis: a multicenter report. Fertil. Steril.82, 292–294 (2004).
  • Harper J, Boelaert K, Geraeadts J et al. ESHRE PGD Consortium data collection V: cycles from January to December 2002 with pregnancy follow-up to October 2003. Hum. Reprod.21, 3–21 (2006).
  • Shahine LK, Cedars M. Preimplantation genetic diagnosis does not increase pregnancy rates in patients at risk for aneuploidy. Fertil. Steril.85, 51–56 (2006).
  • Donoso P, Staessen C, Fauser B, Devroey P. Current value of preimplantation genetic aneuploidy screening in IVF. Hum. Reprod. Update13, 15–25 (2007).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.