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Drug profile

Dual daclatasvir and sofosbuvir for treatment of genotype 3 chronic hepatitis C virus infection

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References

  • Papers of special note have been highlighted as:
  • * Of interest
  • ** Of considerable interest
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** Of considerable importance as this is the first phase III study evaluating sofosbuvir and daclatasvir for hepatitis C virus genotype 3.

  • Hezode C, De Ledinghen V, Fontaine H, et al. LP05: daclatasvir plus sofosbuvir with or without ribavirin in patients with HCV genotype 3 infection: interim analysis of a French multicenter compassionate use program. J Hepatol. 2015;62:S265–S66. DOI:10.1016/S0168-8278(15)30159-8.

** Of considerable importance as this illustrates the benefits of extended therapy to 24 weeks of sofosbuvir and daclatasvir in patients with cirrhosis.

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