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Review

Genetics and genomics in human lung transplantation

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Pages 271-278 | Published online: 09 Jan 2014

References

  • Hosenpud JD, Bennett LE, Keck BM, Boucek MM, Novick RJ. The Registry of the International Society for Heart and Lung Transplantation: seventeenth official report–2000. J. Heart Lung Transplant.19(10), 909–931 (2000).
  • McDyer JF. Human and murine obliterative bronchiolitis in transplant. Proc. Am. Thorac. Soc.4(1), 37–43 (2007).
  • Glanville AR. The role of bronchoscopic surveillance monitoring in the care of lung transplant recipients. Semin. Respir. Crit. Care Med.27(5), 480–491 (2006).
  • You L. Toward computational systems biology. Cell Biochem. Biophys.40(2), 167–184 (2004).
  • Lander ES, Linton LM, Birren B et al. Initial sequencing and analysis of the human genome. Nature409(6822), 860–921 (2001).
  • Futreal PA, Coin L, Marshall M et al. A census of human cancer genes. Nat. Rev.4(3), 177–183 (2004).
  • Ozaki K, Inoue K, Sato H et al. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro. Nature429(6987), 72–75 (2004).
  • Ozaki K, Ohnishi Y, Iida A et al. Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction. Nat. Genet.32(4), 650–654 (2002).
  • Saxena R, Voight BF, Lyssenko V et al. Genome-wide association analysis identifies loci for Type 2 diabetes and triglyceride levels. Science316(5829), 1331–1336 (2007).
  • Scott LJ, Mohlke KL, Bonnycastle LL et al. A genome-wide association study of Type 2 diabetes in Finns detects multiple susceptibility variants. Science316(5829), 1341–1345 (2007).
  • Zeggini E, Weedon MN, Lindgren CM et al. Replication of genome-wide association signals in U.K. samples reveals risk loci for Type 2 diabetes. Science316(5829), 1336–1341 (2007).
  • Dewan A, Liu M, Hartman S et al.HTRA1 promoter polymorphism in wet age-related macular degeneration. Science314(5801), 989–992 (2006).
  • Yang Z, Camp NJ, Sun H et al. A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science314(5801), 992–993 (2006).
  • Coon KD, Myers AJ, Craig DW et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer’s disease. J. Clin. Psychiatry68(4), 613–618 (2007).
  • Ozaki K, Sato H, Iida A et al. A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population. Nat. Genet.38(8), 921–925 (2006).
  • Hampe J, Franke A, Rosenstiel P et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet.39(2), 207–211 (2007).
  • Gibbs RA, Belmont JW, Hardenbol P et al. The International HapMap Project. Nature426(6968), 789–796 (2003).
  • Fischereder M, Luckow B, Hocher B et al. CC chemokine receptor 5 and renal-transplant survival. Lancet357(9270), 1758–1761 (2001).
  • Brown KM, Kondeatis E, Vaughan RW et al. Influence of donor C3 allotype on late renal-transplantation outcome. N. Engl. J. Med.354(19), 2014–2023 (2006).
  • Barnard JB, Richardson S, Sheldon S et al. The MDR1/ABCB1 gene, a high-impact risk factor for cardiac transplant rejection. Transplantation82(12), 1677–1682 (2006).
  • Lee H, Clark B, Gooi HC, Stoves J, Newstead CG. Influence of recipient and donor IL-1α, IL-4, and TNFα genotypes on the incidence of acute renal allograft rejection. J. Clin. Pathol.57(1), 101–103 (2004).
  • Pawlik A, Domanski L, Rozanski J et al. IL-2 and TNF-α promoter polymorphisms in patients with acute kidney graft rejection. Transplant. Proc.37(5), 2041–2043 (2005).
  • Holweg CT, Weimar W, Uitterlinden AG, Baan CC. Clinical impact of cytokine gene polymorphisms in heart and lung transplantation. J. Heart Lung Transplant.23(9), 1017–1026 (2004).
  • Snyder LD, Hartwig MG, Ganous T et al. Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant. J. Heart Lung Transplant.25(11), 1330–1335 (2006).
  • Palmer SM, Burch LH, Davis RD et al. The role of innate immunity in acute allograft rejection after lung transplantation. Am. J. Respir. Crit. Care Med.168(6), 628–632 (2003).
  • Palmer SM, Burch LH, Trindade AJ et al. Innate immunity influences long-term outcomes after human lung transplant. Am. J. Respir. Crit. Care Med.171(7), 780–785 (2005).
  • Palmer SM, Klimecki W, Yu L et al. Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14. Am. J. Transplant.7(3), 693–699 (2007).
  • Horwitz PA, Tsai EJ, Putt ME et al. Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation110(25), 3815–3821 (2004).
  • Deng MC, Eisen HJ, Mehra MR et al. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am. J. Transplant.6(1), 150–160 (2006).
  • Starling RC, Pham M, Valantine H et al. Molecular testing in the management of cardiac transplant recipients: initial clinical experience. J. Heart Lung Transplant.25(12), 1389–1395 (2006).
  • Sarwal M, Chua MS, Kambham N et al. Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N. Engl. J. Med.349(2), 125–138 (2003).
  • Flechner SM, Kurian SM, Head SR et al. Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes. Am. J. Transplant.4(9), 1475–1489 (2004).
  • Li B, Hartono C, Ding R et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N. Engl. J. Med.344(13), 947–954 (2001).
  • Muthukumar T, Dadhania D, Ding R et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N. Engl. J. Med.353(22), 2342–2351 (2005).
  • Hotchkiss H, Chu TT, Hancock WW et al. Differential expression of profibrotic and growth factors in chronic allograft nephropathy. Transplantation81(3), 342–349 (2006).
  • Mas V, Maluf D, Archer K et al. Establishing the molecular pathways involved in chronic allograft nephropathy for testing new noninvasive diagnostic markers. Transplantation83(4), 448–457 (2007).
  • Scherer A, Krause A, Walker JR et al. Early prognosis of the development of renal chronic allograft rejection by gene expression profiling of human protocol biopsies. Transplantation75(8), 1323–1330 (2003).
  • Gimino VJ, Lande JD, Berryman TR, King RA, Hertz MI. Gene expression profiling of bronchoalveolar lavage cells in acute lung rejection. Am. J. Respir. Crit. Care Med.168(10), 1237–1242 (2003).
  • Lande JD, Dalheimer SL, Mueller DL, Hertz MI, King RA. Gene expression profiling in murine obliterative airway disease. Am. J. Transplant.5(9), 2170–2184 (2005).
  • Lu BS, Yu AD, Zhu X et al. Sequential gene expression profiling in lung transplant recipients with chronic rejection. Chest130(3), 847–854 (2006).
  • Xu X, Golden JA, Dolganov G et al. Transcript signatures of lymphocytic bronchitis in lung allograft biopsy specimens. J. Heart Lung Transplant.24(8), 1055–1066 (2005).
  • Morgun A, Shulzhenko N, Perez-Diez A et al. Molecular profiling improves diagnoses of rejection and infection in transplanted organs. Circ. Res.98(12), E74–E83 (2006).
  • Nelsestuen GL, Martinez MB, Hertz MI, Savik K, Wendt CH. Proteomic identification of human neutrophil α-defensins in chronic lung allograft rejection. Proteomics5(6), 1705–1713 (2005).

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