1,038
Views
73
CrossRef citations to date
0
Altmetric
Review

Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature

, , , , , & show all

References

  • Anandan C, Nurmatov U, van Schayck OC, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy 2010;65(2):152-67
  • Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31(1):143-78
  • Asher MI, Montefort S, Björkstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006;368(9537):733-43
  • Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med 2006;355(21):2226-35
  • Beasley R, Crane J, Lai CK, Pearce N. Prevalence and etiology of asthma. J Allergy Clin Immunol 2000;105(2 Pt 2):S466-72
  • Jenkins MA, Hopper JL, Bowes G, et al. Factors in childhood as predictors of asthma in adult life. BMJ 1994;309(6947):90-3
  • Rhodes L, Moorman JE, Redd SC. Sex differences in asthma prevalence and other disease characteristics in eight states. J Asthma 2005;42(9):777-82
  • Burgess JA, Walters EH, Byrnes GB, et al. Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study. J Allergy Clin Immunol 2007;120(4):863-9
  • Jenkins HA, Cherniack R, Szefler SJ, et al. A comparison of the clinical characteristics of children and adults with severe asthma. Chest 2003;124(4):1318-24
  • Lange P, Parner J, Vestbo J, et al. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 1998;339(17):1194-200
  • Perret JL, Dharmage SC, Matheson MC, et al. The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age. Am J Respir Crit Care Med 2013;187(1):42-8
  • Lange P. Prognosis of adult asthma. Monaldi Arch Chest Dis 1999;54(4):350-2
  • Burgess JA, Matheson MC, Gurrin LC, et al. Factors influencing asthma remission: a longitudinal study from childhood to middle age. Thorax 2011;66(6):508-13
  • Lawson JA, Janssen I, Bruner MW, et al. Asthma incidence and risk factors in a national longitudinal sample of adolescent Canadians: a prospective cohort study. BMC Pulm Med 2014;14(1):51
  • Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 2012;18(5):716-25
  • Siroux V, Basagaña X, Boudier A, et al. Identifying adult asthma phenotypes using a clustering approach. Eur Respir J 2011;38(2):310-17
  • Montuschi P, Barnes PJ. New perspectives in pharmacological treatment of mild persistent asthma. Drug Discov Today 2011;16(23-24):1084-91
  • Montuschi P, Mores N, Trové A, et al. The electronic nose in respiratory medicine. Respiration 2013;85(1):72-84
  • Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet 2006;368(9537):804-13
  • Haldar P, Pavord ID, Shaw DE, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 2008;178(3):218-24
  • Moore WC, Meyers DA, Wenzel SE, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010;181(4):315-23
  • de Nijs SB, Venekamp LN, Bel EH. Adult-onset asthma: is it really different? Eur Respir Rev 2013;22(127):44-52
  • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557-60
  • Holguin F, Comhair SA, Hazen SL, et al. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med 2013;187(2):153-9
  • Rossall M, Cadden P, Kolsum U, Singh D. A comparison of the clinical and induced sputum characteristics of early- and late-onset asthma. Lung 2012;190(4):459-62
  • Holguin F, Bleecker ER, Busse WW, et al. Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol 2011;127(6):1486-93.e2
  • Hsu JY, King SL, Kuo BI, Chiang CD. Age of onset and the characteristics of asthma. Respirology 2004;9(3):369-72
  • Ségala C, Priol G, Soussan D, et al. Asthma in adults: comparison of adult-onset asthma with childhood-onset asthma relapsing in adulthood. Allergy 2000;55(7):634-40
  • Khin-Maung U, Aung-Than B. House-dust mite allergy and eosinophilia in patients with asthma in Rangoon (Yangon). J Asthma 1992;29(6):383-91
  • de Carvalho-Pinto RM, Cukier A, Angelini L, et al. Clinical characteristics and possible phenotypes of an adult severe asthma population. Respir Med 2012;106(1):47-56
  • Miranda C, Busacker A, Balzar S, et al. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004;113(1):101-8
  • ten Brinke A, van Dissel JT, Sterk PJ, et al. Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. J Allergy Clin Immunol 2001;107(3):449-54
  • Almqvist C, Worm M, Leynaert B; Working group of GA2LEN WP 2.5 Gender. Impact of gender on asthma in childhood and adolescence: a GA2LEN review. Allergy 2008;63(1):47-57
  • Bjornson CL, Mitchell I. Gender differences in asthma in childhood and adolescence. J Gend Specif Med 2000;3(8):57-61
  • Postma DS. Gender differences in asthma development and progression. Gend Med 2007;4(Suppl B):S133-46
  • Chen W, Mempel M, Schober W, et al. Gender difference, sex hormones, and immediate type hypersensitivity reactions. Allergy 2008;63(11):1418-27
  • Sears MR, Burrows B, Flannery EM, et al. Atopy in childhood. I. Gender and allergen related risks for development of hay fever and asthma. Clin Exp Allergy 1993;23(11):941-8
  • Pang JJ, Xu XB, Li HF, et al. Inhibition of beta-estradiol on trachea smooth muscle contraction in vitro and in vivo. Acta Pharmacol Sin 2002;23(3):273-7
  • Leung GP, Cheng-Chew SB, Wong PY. Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia. Am J Physiol Cell Physiol 2001;280(5):C1160-7
  • Pearce N, Pekkanen J, Beasley R. How much asthma is really attributable to atopy? Thorax 1999;54(3):268-72
  • Lau S, Illi S, Sommerfeld C, et al. Early exposure to house-dust mite and cat allergens and development of childhood asthma: a cohort study. Multicentre Allergy Study Group. Lancet 2000;356(9239):1392-7
  • Howard TD, Whittaker PA, Zaiman AL, et al. Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am J Respir Cell Mol Biol 2001;25(3):377-84
  • Bouzigon E, Corda E, Aschard H, et al. Effect of 17q21 variants and smoking exposure in early-onset asthma. N Engl J Med 2008;359(19):1985-94
  • Moffatt MF, Gut IG, Demenais F, et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010;363(13):1211-21
  • London SJ, James Gauderman W, Avol E, et al. Family history and the risk of early-onset persistent, early-onset transient, and late-onset asthma. Epidemiology 2001;12(5):577-83
  • Romanet-Manent S, Charpin D, Magnan A, et al. Allergic vs nonallergic asthma: what makes the difference? Allergy 2002;57(7):607-13
  • Holguin F. Obesity as a risk factor for increased asthma severity and allergic inflammation; cause or effect? Clin Exp Allergy 2012;42(5):612-13
  • Melgert BN, Ray A, Hylkema MN, et al. Are there reasons why adult asthma is more common in females? Curr Allergy Asthma Rep 2007;7(2):143-50
  • Polosa R, Knoke JD, Russo C, et al. Cigarette smoking is associated with a greater risk of incident asthma in allergic rhinitis. J Allergy Clin Immunol 2008;121(6):1428-34
  • Thomson NC, Chaudhuri R. Asthma in smokers: challenges and opportunities. Curr Opin Pulm Med 2009;15(1):39-45
  • Westerhof GA, Vollema EM, Weersink EJ, et al. Predictors for the development of progressive severity in new-onset adult asthma. J Allergy Clin Immunol 2014;134(5):1051-1056.e2
  • Le Moual N, Carsin AE, Siroux V, et al. Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II. Eur Respir J 2014;43(2):374-86
  • Silva GE, Sherrill DL, Guerra S, Barbee RA. Asthma as a risk factor for COPD in a longitudinal study. Chest 2004;126(1):59-65
  • Zeki AA, Schivo M, Chan A, et al. The asthma-COPD overlap syndrome: a common clinical problem in the elderly. J Allergy (Cairo) 2011;2011:861926
  • Gibson PG, Simpson JL. The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax 2009;64(8):728-35
  • Montuschi P, Malerba M, Santini G, Miravitlles M. Pharmacological treatment of chronic obstructive pulmonary disease: from evidence-based medicine to phenotyping. Drug Discov Today 2014;19(12):1928-35
  • Wenzel S. Severe asthma in adults. Am J Respir Crit Care Med 2005;172(2):149-60
  • Just J, Gouvis-Echraghi R, Rouve S, et al. Two novel, severe asthma phenotypes identified during childhood using a clustering approach. Eur Respir J 2012;40(1):55-60
  • Torén K, Palmqvist M, Löwhagen O, et al. Self-reported asthma was biased in relation to disease severity while reported year of asthma onset was accurate. J Clin Epidemiol 2006;59(1):90-3
  • Pattaro C, Locatelli F, Sunyer J, de Marco R. Using the age at onset may increase the reliability of longitudinal asthma assessment. J Clin Epidemiol 2007;60(7):704-11
  • Brogger J, Eagan T, Eide GE, et al. Bias in retrospective studies of trends in asthma incidence. Eur Respir J 2004;23(2):281-6
  • Burgess JA, Walters EH, Byrnes GB, et al. Who remembers whether they had asthma as children? J Asthma 2006;43(10):727-30
  • Strachan DP, Griffiths JM, Johnston ID, Anderson HR. Ventilatory function in British adults after asthma or wheezing illness at ages 0-35. Am J Respir Crit Care Med 1996;154(6 Pt 1):1629-35
  • Abramson MJ, Perret JL, Dharmage SC, et al. Distinguishing adult-onset asthma from COPD: a review and a new approach. Int J Chron Obstruct Pulmon Dis 2014;9:945-62

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.