89
Views
15
CrossRef citations to date
0
Altmetric
Review

Immunoisolation: where regenerative medicine meets solid organ transplantation

, , , , , , , , & show all
Pages 685-692 | Published online: 10 Jan 2014

References

  • Orlando G, Bendala JD, Shupe T et al. Cell and organ bioengineering technology as applied to gastrointestinal diseases. Gut doi:10.1136/gutjnl-2011-301111 (2012) (Epub ahead of print).
  • Orlando G. Transplantation as a subfield of regenerative medicine. Interview by Lauren Constable. Expert Rev. Clin. Immunol. 7(2), 137–141 (2011).
  • Orlando G. Immunosuppression-free transplantation reconsidered from a regenerative medicine perspective. Expert Rev. Clin. Immunol. 8(2), 179–187 (2012).
  • Orlando G, Wood KJ, Soker S, Stratta RJ. How regenerative medicine may contribute to the achievement of an immunosuppression-free state. Transplantation 92(8), e36–e38; author reply e39 (2011).
  • Thomas L. The technology of medicine. N. Engl. J. Med. 285(24), 1366–1368 (1971).
  • Oliver TR. Health care reform as a halfway technology. J. Health Polit. Policy Law 36(3), 603–609 (2011).
  • Thomas L. Lives of a Cell. Viking Press, New York, NY, USA (1974).
  • Rubín A, Aguilera V, Berenguer M. Liver transplantation and hepatitis C. Clin. Res. Hepatol. Gastroenterol. 35(12), 805–812 (2011).
  • Orlando G, Hematti P, Stratta RJ et al. Clinical operational tolerance after renal transplantation: current status and future challenges. Ann. Surg. 252(6), 915–928 (2010).
  • Orlando G, Soker S, Wood K. Operational tolerance after liver transplantation. J. Hepatol. 50(6), 1247–1257 (2009).
  • Opara EC, Mirmalek-Sani SH, Khanna O, Moya ML, Brey EM. Design of a bioartificial pancreas(+). J. Investig. Med. 58(7), 831–837 (2010).
  • Hill RS, Cruise GM, Hager SR et al. Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of mass-isolated porcine islets. Ann. NY Acad. Sci. 831, 332–343 (1997).
  • Avgoustiniatos ES, Colton CK. Effect of external oxygen mass transfer resistances on viability of immunoisolated tissue. Ann. NY Acad. Sci. 831, 145–167 (1997).
  • O’Sullivan ES, Vegas A, Anderson DG, Weir GC. Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocr. Rev. 32(6), 827–844 (2011).
  • Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 210(4472), 908–910 (1980).
  • Calafiore R, Basta G, Luca G et al. Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with type 1 diabetes: first two cases. Diabetes Care 29(1), 137–138 (2006).
  • Elliott RB, Escobar L, Tan PL, Muzina M, Zwain S, Buchanan C. Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xenotransplantation 14(2), 157–161 (2007).
  • Soon-Shiong P, Feldman E, Nelson R et al. Successful reversal of spontaneous diabetes in dogs by intraperitoneal microencapsulated islets. Transplantation 54(5), 769–774 (1992).
  • Prokop A. Bioartificial pancreas: materials, devices, function, and limitations. Diabetes Technol. Ther. 3(3), 431–449 (2001).
  • de Groot M, Schuurs TA, van Schilfgaarde R. Causes of limited survival of microencapsulated pancreatic islet grafts. J. Surg. Res. 121(1), 141–150 (2004).
  • Kizilel S, Garfinkel M, Opara E. The bioartificial pancreas: progress and challenges. Diabetes Technol. Ther. 7(6), 968–985 (2005).
  • Pareta RA, McQuilling JP, Farney A et al. Bioartificial pancreas: evaluation of crucial barriers to clinical application. In: Organ Donation and Transplantation – Public Policy and Clinical Perspectives. Randhawa G (Ed.). INTECH Publishers, Rijeka, Croatia 241–266 (2012).
  • Smidsrød O, Skjåk-Braek G. Alginate as immobilization matrix for cells. Trends Biotechnol. 8(3), 71–78 (1990).
  • Holtan S, Zhang Q, Strand WI, Skjåk-Braek G. Characterization of the hydrolysis mechanism of polyalternating alginate in weak acid and assignment of the resulting MG-oligosaccharides by NMR spectroscopy and ESI-mass spectrometry. Biomacromolecules 7(7), 2108–2121 (2006).
  • Maki T, Lodge JP, Carretta M et al. Treatment of severe diabetes mellitus for more than one year using a vascularized hybrid artificial pancreas. Transplantation 55(4), 713–7; discussion 717 (1993).
  • Zekorn T, Horcher A, Siebers U, Federlin K, Bretzel RG. Islet transplantation in immunoseparating membranes for treatment of insulin-dependent diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 103(Suppl. 2), 136–139 (1995).
  • de Vos P, Hamel AF, Tatarkiewicz K. Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia 45(2), 159–173 (2002).
  • Zielinski BA, Aebischer P. Chitosan as a matrix for mammalian cell encapsulation. Biomaterials 15(13), 1049–1056 (1994).
  • Iwata H, Amemiya H, Matsuda T, Takano H, Hayashi R, Akutsu T. Evaluation of microencapsulated islets in agarose gel as bioartificial pancreas by studies of hormone secretion in culture and by xenotransplantation. Diabetes 38(Suppl. 1), 224–225 (1989).
  • Risbud MV, Bhonde RR. Suitability of cellulose molecular dialysis membrane for bioartificial pancreas: in vitro biocompatibility studies. J. Biomed. Mater. Res. 54(3), 436–444 (2001).
  • Dawson RM, Broughton RL, Stevenson WT, Sefton MV. Microencapsulation of CHO cells in a hydroxyethyl methacrylate-methyl methacrylate copolymer. Biomaterials 8(5), 360–366 (1987).
  • Kessler L, Pinget M, Aprahamian M, Dejardin P, Damgé C. In vitro and in vivo studies of the properties of an artificial membrane for pancreatic islet encapsulation. Horm. Metab. Res. 23(7), 312–317 (1991).
  • Cruise GM, Hegre OD, Lamberti FV et al. In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized poly(ethylene glycol) diacrylate membranes. Cell Transplant. 8(3), 293–306 (1999).
  • Donati I, Holtan S, Mørch YA, Borgogna M, Dentini M, Skjåk-Braek G. New hypothesis on the role of alternating sequences in calcium-alginate gels. Biomacromolecules 6(2), 1031–1040 (2005).
  • Mørch YA, Qi M, Gundersen PO et al. Binding and leakage of barium in alginate microbeads. J. Biomed. Mater. Res. A 100(11), 2939–2947 (2012).
  • Soon-Shiong P, Heintz RE, Merideth N et al. Insulin independence in a Type 1 diabetic patient after encapsulated islet transplantation. Lancet 343(8903), 950–951 (1994).
  • Chaikof EL. Engineering and material considerations in islet cell transplantation. Annu. Rev. Biomed. Eng. 1, 103–127 (1999).
  • Wolters GH, Fritschy WM, Gerrits D, van Schilfgaarde R. A versatile alginate droplet generator applicable for microencapsulation of pancreatic islets. J. Appl. Biomater. 3(4), 281–286 (1991).
  • Hallé JP, Leblond FA, Pariseau JF, Jutras P, Brabant MJ, Lepage Y. Studies on small (<300 microns) microcapsules: II–Parameters governing the production of alginate beads by high voltage electrostatic pulses. Cell Transplant. 3(5), 365–372 (1994).
  • Hsu BR, Chen HC, Fu SH, Huang YY, Huang HS. The use of field effects to generate calcium alginate microspheres and its application in cell transplantation. J. Formos. Med. Assoc. 93(3), 240–245 (1994).
  • Dawson RM, Broughton RL, Stevenson WT et al. Microencapsulation of CHO cells in a hydroxyethyl methacrylate-methyl methacrylate copolymer. Biomaterials 8, 360–366 (1987).
  • Desmangles AI, Jordan O, Marquis-Weible F. Interfacial photopolymerization of β-cell clusters: approaches to reduce coating thickness using ionic and lipophilic dyes. Biotechnol. Bioeng. 72(6), 634–641 (2001).
  • Senuma Y, Lowe C, Zweifel Y, Hilborn JG, Marison I. Alginate hydrogel microspheres and microcapsules prepared by spinning disk atomization. Biotechnol. Bioeng. 67(5), 616–622 (2000).
  • Omer A, Duvivier-Kali V, Fernandes J, Tchipashvili V, Colton CK, Weir GC. Long-term normoglycemia in rats receiving transplants with encapsulated islets. Transplantation 79(1), 52–58 (2005).
  • Lanza RP, Kühtreiber WM, Ecker D, Staruk JE, Chick WL. Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres. Transplantation 59(10), 1377–1384 (1995).
  • van Schilfgaarde R, de Vos P. Factors influencing the properties and performance of microcapsules for immunoprotection of pancreatic islets. J. Mol. Med. 77(1), 199–205 (1999).
  • Bystrický S, Malovíková A et al. Interaction of alginates and pectins with cationic polypeptides. Carbohydrate Polymers 13(3), 283–294 (1990).
  • Thu B, Bruheim P, Espevik T, Smidsrød O, Soon-Shiong P, Skjåk-Braek G. Alginate polycation microcapsules. II. Some functional properties. Biomaterials 17(11), 1069–1079 (1996).
  • King GA, Daugulis AJ et al. Alginate-polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering. Biotech. Progress 3(4), 231–240 (1987).
  • Kulseng B, Thu B, Espevik T, Skjåk-Braek G. Alginate polylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane. Cell Transplant. 6(4), 387–394 (1997).
  • Darrabie M, Freeman BK, Kendall WF Jr, Hobbs HA, Opara EC. Durability of sodium sulfate-treated polylysine-alginate microcapsules. J. Biomed. Mater. Res. 54(3), 396–399 (2001).
  • Gugerli R, Cantana E, Heinzen C, von Stockar U, Marison IW. Quantitative study of the production and properties of alginate/poly-l-lysine microcapsules. J. Microencapsul. 19(5), 571–590 (2002).
  • Darrabie MD, Kendall WF Jr, Opara EC. Characteristics of Poly-l-Ornithine-coated alginate microcapsules. Biomaterials 26(34), 6846–6852 (2005).
  • Thu B, Bruheim P, Espevik T, Smidsrød O, Soon-Shiong P, Skjåk-Braek G. Alginate polycation microcapsules. I. Interaction between alginate and polycation. Biomaterials 17(10), 1031–1040 (1996).
  • Strand BL, Ryan TL, In’t Veld P et al. Poly-l-Lysine induces fibrosis on alginate microcapsules via the induction of cytokines. Cell Transplant. 10(3), 263–275 (2001).
  • Clayton HA, London NJ, Colloby PS, Bell PR, James RF. The effect of capsule composition on the biocompatibility of alginate-poly-l-lysine capsules. J. Microencapsul. 8(2), 221–233 (1991).
  • Bünger CM, Gerlach C, Freier T et al. Biocompatibility and surface structure of chemically modified immunoisolating alginate-PLL capsules. J. Biomed. Mater. Res. A 67(4), 1219–1227 (2003).
  • Brunetti P, Basta G, Faloerni A, Calcinaro F, Pietropaolo M, Calafiore R. Immunoprotection of pancreatic islet grafts within artificial microcapsules. Int. J. Artif. Organs 14(12), 789–791 (1991).
  • Calafiore R, Basta G, Boselli C et al. Effects of alginate/polyaminoacidic coherent microcapsule transplantation in adult pigs. Transplant. Proc. 29(4), 2126–2127 (1997).
  • Calafiore R, Basta G, Luca G et al. Grafts of microencapsulated pancreatic islet cells for the therapy of diabetes mellitus in non-immunosuppressed animals. Biotechnol. Appl. Biochem. 39(Pt. 2), 159–164 (2004).
  • Ching CD, Harland RC, Collins BH, Kendall W, Hobbs H, Opara EC. A reliable method for isolation of viable porcine islet cells. Arch. Surg. 136(3), 276–279 (2001).
  • Inaki Y, Tohnai N, Miyabayashi K, Miyata M. Isopoly-L-ornithine derivative as nucleic acid model. Nucleic Acids Symp. Ser. 37, 25–26 (1997).
  • De Castro M, Orive G, Hernandex RM et al. Comparitive study of microcapsules elaborated with three polycations (PLL, PDL, PLO) for cell immobilization. J. Microsurg. 25(6), 387–398 (2008).
  • Toso C, Mathe Z, Morel P et al. Effect of microcapsule composition and short-term immunosuppression on intraportal biocompatibility. Cell Transplant. 14(2–3), 159–167 (2005).
  • Dufrane D, Goebbels RM, Saliez A, Guiot Y, Gianello P. Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: proof of concept. Transplantation 81(9), 1345–1353 (2006).
  • Dufrane D, Steenberghe M, Goebbels RM, Saliez A, Guiot Y, Gianello P. The influence of implantation site on the biocompatibility and survival of alginate encapsulated pig islets in rats. Biomaterials 27(17), 3201–3208 (2006).
  • Kin T, Korbutt GS, Rajotte RV. Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch. Am. J. Transplant. 3(3), 281–285 (2003).
  • Kobayashi T, Aomatsu Y, Iwata H et al. Survival of microencapsulated islets at 400 days posttransplantation in the omental pouch of NOD mice. Cell Transplant. 15(4), 359–365 (2006).
  • Moya ML, Cheng MH, Huang JJ et al. The effect of FGF-1 loaded alginate microbeads on neovascularization and adipogenesis in a vascular pedicle model of adipose tissue engineering. Biomaterials 31(10), 2816–2826 (2010).
  • Calafiore R, Basta G, Luca G et al. Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with Type 1 diabetes. Diabetes Care 29(1), 137–138 (2006).
  • de Vos P, Faas MM, Strand B, Calafiore R. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials 27(32), 5603–5617 (2006).
  • Brasile L, Glowacki P, Stubenitsky BM. Bioengineered skin allografts: a new method to prevent humoral response. ASAIO J. 57(3), 239–243 (2011).
  • Brasile L, Glowacki P, Castracane J, Stubenitsky BM. Pretransplant kidney-specific treatment to eliminate the need for systemic immunosuppression. Transplantation 90(12), 1294–1298 (2010).
  • Stubenitsky BM, Brasile L, Rebellato LM, Hawinkels H, Haisch C, Kon M. Delayed skin allograft rejection following matrix membrane pretreatment. J. Plast. Reconstr. Aesthet. Surg. 62(4), 520–525 (2009).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.