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Review

Nutritional lipid and antioxidant supplements: risks versus benefits

Pages 483-492 | Published online: 10 Jan 2014

References

  • Harman D. Role of free radicals in mutation, cancer, aging, and the maintenance of life. Radiat. Res. 16, 753–763 (1962).
  • Halliwell B. Reactive oxygen species in pathology with special reference to the skin. In: Oxidative Stress in Dermatology, Fuchs J, Packer L (Eds). Marcel Dekker, Inc., NY, USA 3–11 (1993).
  • Elmets CA, Mukhtar H. Ultraviolet radiation and skin cancer: progress in pathophysiologic mechanisms. Prog. Dermatol. 30, 1–16 (1996).
  • Norins AL. Free radical formation in the skin following exposure to ultraviolet light. J. Invest. Dermatol. 39, 445–448 (1962).
  • Black HS, Lenger W, McCann V, Thornby JI. Relation of UV dose to antioxidant modification of photocarcinogenesis. J. Am. Col. Toxicol. 2, 201–207 (1983).
  • Black HS, Lenger WA, Gerguis J, Thornby JI. Relation of antioxidants and level of dietary lipid to epidermal lipid peroxidation and ultraviolet carcinogenesis. Cancer Res. 45(12 Pt 1), 6254–6259 (1985).
  • Black HS, Chan JT. Suppression of ultraviolet light-induced tumor formation by dietary antioxidants. J. Invest. Dermatol. 65(4), 412–414 (1975).
  • Harmon D. The free radical theory of aging. In: Free Radicals in Biology, Pryor WA (Ed.). Academic Press, NY, USA 255–275 (1982).
  • Baumann CA, Rusch HP. Effect of diet on tumors induced by ultraviolet light. Am. J. Cancer 35, 213–221 (1939).
  • Black HS. Effects of dietary antioxidants on actinic tumor induction. Res. Commun. Chem. Pathol. Pharmacol. 7(4), 783–786 (1974).
  • Black HS, Lenger W, Phelps AW, Thornby JI. Influence of dietary lipid upon ultraviolet-light carcinogenesis. Nutr. Cancer 5(2), 59–68 (1983).
  • Black HS, Thornby JI, Gerguis J, Lenger W. Influence of dietary omega-6, -3 fatty acid sources on the initiation and promotion stages of photocarcinogenesis. Photochem. Photobiol. 56(2), 195–199 (1992).
  • Black HS, Herd JA, Goldberg LH et al. Effect of a low-fat diet on the incidence of actinic keratosis. N. Engl. J. Med. 330(18), 1272–1275 (1994).
  • Jaax S, Scott LW, Wolf JE Jr, Thornby JI, Black HS. General guidelines for a low-fat diet effective in the management and prevention of nonmelanoma skin cancer. Nutr. Cancer 27(2), 150–156 (1997).
  • Orengo IF, Black HS, Kettler AH, Wolf JE Jr. Influence of dietary menhaden oil upon carcinogenesis and various cutaneous responses to ultraviolet radiation. Photochem. Photobiol. 49(1), 71–77 (1989).
  • Vanderveen EE, Grekin RC, Swanson NA, Kragballe K. Arachidonic acid metabolites in cutaneous carcinomas. Evidence suggesting that elevated levels of prostaglandins in basal cell carcinomas are associated with an aggressive growth pattern. Arch. Dermatol. 122(4), 407–412 (1986).
  • Fischer MA, Black HS. Modification of membrane composition, eicosanoid metabolism, and immunoresponsiveness by dietary omega-3 and omega-6 fatty acid sources, modulators of ultraviolet-carcinogenesis. Photochem. Photobiol. 54(3), 381–387 (1991).
  • Cadenas E, Sies H, Nastainczyk W, Ullrich V. Singlet oxygen formation detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2. Hoppe-Seyler’s Z. Physiol. Chem. 364(5), 519–528 (1983).
  • Reeve VE, Bosnic M, Boehm-Wilcox C. Dependence of photocarcinogenesis and photoimmunosuppression in the hairless mouse on dietary polyunsaturated fat. Cancer Lett. 108(2), 271–279 (1996).
  • Chung HT, Burnham DK, Robertson B, Roberts LK, Daynes RA. Involvement of prostaglandins in the immune alterations caused by the exposure of mice to ultraviolet radiation. J. Immunol. 137(8), 2478–2484 (1986).
  • Orengo IF, Gerguis J, Phillips R, Guevara A, Lewis AT, Black HS. Celecoxib, a cyclooxygenase 2 inhibitor as a potential chemopreventive to UV-induced skin cancer: a study in the hairless mouse model. Arch. Dermatol. 138(6), 751–755 (2002).
  • Elmets CA, Viner JL, Pentland AP et al. Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial. J. Natl Cancer Inst. 102(24), 1835–1844 (2010).
  • Black HS, Okotie-Eboh G, Gerguis J, Urban JI, Thornby JI. Dietary fat modulates immunoresponsiveness in UV-irradiated mice. Photochem. Photobiol. 62(6), 964–969 (1995).
  • Black HS, Rhodes LE. The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. Cancer Detect. Prev. 30(3), 224–232 (2006).
  • Pilkington SM, Watson RE, Nicolaou A, Rhodes LE. Omega-3 polyunsaturated fatty acids: photoprotective macronutrients. Exp. Dermatol. 20(7), 537–543 (2011).
  • Black HS. ω-3 fatty acids and non-melanoma skin cancer. In: Handbook of Diet, Nutrition and the Skin. Preedy VR. (Ed.). Wageningen Academic Publishers, The Netherlands 367–378 (2012).
  • Pauling L, Willoughby R, Reynolds R, Blaisdell BE, Lawson S. Incidence of squamous cell carcinoma in hairless mice irradiated with ultraviolet light in relation to intake of ascorbic acid (vitamin C) and of D, L-alpha-tocopheryl acetate (vitamin E). Int. J. Vitam. Nutr. Res. Suppl. 23, 53–82 (1982).
  • Black HS, Chan JT, Brown GE. Effects of dietary constituents on ultraviolet light-mediated carcinogenesis. Cancer Res. 38(5), 1384–1387 (1978).
  • Black HS, Kleinhans CM, Hudson HT, Sayre RM, Agin PP. Studies on the mechanism of protection by butylated hydroxytoluene to UV-radiation damage. Photobiochem. Photobiophys. 1, 119–123 (1980).
  • Black HS, Lenger W, Gerguis J, McCann V. Studies on the photoprotective mechanism of butylated hydroxytoluene. Photochem. Photobiol. 40(1), 69–75 (1984).
  • Koone MD, Black HS. A mode of action for butylated hydroxytoluene-mediated photoprotection. J. Invest. Dermatol. 87(3), 343–347 (1986).
  • Peterson AO, McCann V, Black HS. Dietary modification of UV-induced epidermal ornithine decarboxylase. J. Invest. Dermatol. 75(5), 408–410 (1980).
  • Black HS, Mathews-Roth MM. Protective role of butylated hydroxytoluene and certain carotenoids in photocarcinogenesis. Photochem. Photobiol. 53(5), 707–716 (1991).
  • Chan JT, Ford JO, Rudolph AH, Black HS. Physiological changes in hairless mice maintained on an antioxidant supplemented diet. Experientia 33(1), 41–42 (1977).
  • Black HS, Gerguis J. Use of the Ames test in assessing the relation of dietary lipid and antioxidants to N-2-fluorenylacetamide activation. J. Environ. Pathol. Toxicol. 4(1), 131–138 (1980).
  • Foote CS, Denny RW. Chemistry of singlet oxygen. VII. Quenching by β-carotene. J. Am. Chem. Soc. 90, 6233–6235 (1968).
  • Burton GW, Ingold KU. β-Carotene: an unusual type of lipid antioxidant. Science 224(4649), 569–573 (1984).
  • Black HS, Lambert CR. Radical reactions of carotenoids and potential influence on UV carcinogenesis. Curr. Probl. Dermatol. 29, 140–156 (2001).
  • Mathews-Roth MM, Pathak MA, Fitzpatrick TB, Harber LH, Kass EH. β-carotene therapy for erythropoietic protoporphyria and other photosensitivity diseases. Arch. Dermatol. 113(9), 1229–1232 (1977).
  • Stahl W, Sies H. Photoprotection by dietary carotenoids: concept, mechanisms, evidence and future development. Mol. Nutr. Food Res. 56(2), 287–295 (2012).
  • Peto R, Doll R, Buckley JD, Sporn MB. Can dietary β-carotene materially reduce human cancer rates? Nature 290(5803), 201–208 (1981).
  • Mathews-Roth MM. Antitumor activity of β-carotene, canthaxanthin and phytoene. Oncology 39(1), 33–37 (1982).
  • Mathews-Roth MM, Krinsky NI. Carotenoid dose level and protection against UV-B induced skin tumors. Photochem. Photobiol. 42(1), 35–38 (1985).
  • Greenberg ER, Baron JA, Stukel TA et al. A clinical trial of β-carotene to prevent basal-cell and squamous-cell cancers of the skin. The Skin Cancer Prevention Study Group. N. Engl. J. Med. 323(12), 789–795 (1990).
  • The α-Tocopherol, β-Carotene Cancer Prevention Study Group. The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 330, 1029–1035 (1996).
  • Black HS. Radical interception by carotenoids and effects on UV carcinogenesis. Nutr. Cancer 31(3), 212–217 (1998).
  • Black HS, Okotie-Eboh G, Gerguis J. Diet potentiates the UV-carcinogenic response to β-carotene. Nutr. Cancer 37(2), 173–178 (2000).
  • Sayre RM, Black HS. β-carotene does not act as an optical filter in skin. J. Photochem. Photobiol. B, Biol. 12(1), 83–90 (1992).
  • Truscott TG. β-carotene and disease: a suggested pro-oxidant and anti-oxidant mechanism and speculations concerning its role in cigarette smoking. J. Photochem. Photobiol. B, Biol. 35(3), 233–235 (1996).
  • Edge R, Land EJ, McGarvey D, Mulroy L, Truscott TG. Relative one-electron reduction potentials of carotenoid radical cations and the interactions of carotenoids with the vitamin E radical cation. J. Am. Chem. Soc. 120, 4087–4090 (1998).
  • Black HS, Gerguis J. Modulation of dietary vitamins E and C fails to ameliorate b-carotene exacerbation of UV-carcinogenesis in mice. Nutr. Cancer 45(1), 36–45 (2003).
  • Black HS. Interaction of ascorbic acid and tocopherol on β-carotene modulated carcinogenesis. Hemoglobin 34(3), 284–290 (2010).
  • IARC Working Group on the Evaluation of Cancer Prevention Agents. IARC Handbooks of Cancer Prevention. Carotenoids Vol 2. Lyon, France (1998).
  • Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297(8), 842–857 (2007).
  • Ristow M, Zarse K, Oberbach A et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc. Natl Acad. Sci. USA 106(21), 8665–8670 (2009).
  • Bairati I, Meyer F, Gélinas M et al. A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J. Natl Cancer Inst. 97(7), 481–488 (2005).
  • World Cancer Research Fund/American Institute for Cancer Research, Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. AICR, Washington, DC, USA (2007).

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