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Editorial

Current status of cell therapy for systemic arterial hypertension

, &
Pages 1307-1311 | Published online: 10 Jan 2014

References

  • Cooper RS, Tayo B. Geographic patterns of hypertension: a global perspective. In: Hypertension Primer: The Essentials of High Blood Pressure. 4th Edition. Izzo, JL, Sica DA, Black HR (Eds). Lippincott, Williams and Wilkins, PA, USA, 239–241 (2008).
  • Chobanian AV, Bakris GL, Black HR et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension42(6), 1206–1252 (2003).
  • Pravenec M, Kurtz TW. Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies. Hypertension49(5), 941–952 (2007).
  • Coleman TG, Hall JE. Systemic hemodynamics and regional blood flow regulation. In: Hypertension Primer: The Essentials of High Blood Pressure. 4th Edition. Izzo, JL, Sica DA, Black HR (Eds). Lippincott, Williams and Wilkins, PA, USA, 129–132 (2008).
  • Judy WV. Watanabe AM. Henry DP et al. Sympathetic nerve activity: role in regulation of blood pressure in the spontaneously hypertensive rat. Circ. Res.38(Suppl. 2), 21–29 (1976).
  • Brooks VL, Haywood JR, Johnson AK. Translation of salt retention to central activation of the sympathetic nervous system in hypertension. Clin. Exp. Pharmacol. Physiol.32(5–6), 426–432 (2005).
  • McIntyre M, Bohr DF, Dominiczak AF. Endothelial function in hypertension: the role of superoxide anion. Hypertension34, 539–545 (1999).
  • Touyz RM. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension44, 248–252 (2004).
  • Levy BI, Ambrosio G, Pries AR et al. Microcirculation in hypertension: a new target for treatment? Circulation104, 735–740 (2001).
  • le Noble FA, Stassen FR, Hacking WJ et al. Angiogenesis and hypertension. J. Hypertens.16, 1563–1572 (1998).
  • Wang H, Olszewski, B, Rosebury W et al. Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expression. Biochem. Biophys. Res. Comm.315, 363–368 (2004).
  • Murasawa S, Asahara T. Endothelial progenitor cells for vasculogenesis. Physiology (Bethesda)20, 36–42 (2005).
  • Asahara T, Murohara T, Sullivan A et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science275(5302), 964–967 (1997).
  • Shi Q, Rafii S, Wu MH et al. Evidence for circulating bone marrow-derived endothelial cells. Blood92(2), 362–367 (1998).
  • Peichev M, Naiyer AJ, Pereira D et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood95, 952–958 (2000).
  • Vasa M, Fichtlscherer S, Aicher A et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res.89, E1–E7, (2001).
  • Imanishi T, Moriwaki C, Hano T et al. Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension. J. Hypertens.23(10), 1831–1837 (2005).
  • Werner N, Kosiol S, Schiegl T et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N. Engl. J. Med.353(10), 999–1007 (2005).
  • Pirro M, Schillaci G, Menecali C et al. Reduced number of circulating endothelial progenitors and HOXA9 expression in CD34+ cells of hypertensive patients. J. Hypertens.25(10), 2093–2099 (2007).
  • Oliveras A, Soler MJ, Martínez-Estrada OM et al. Endothelial progenitor cells are reduced in refractory hypertension. J. Hum. Hypertens.22(3), 183–190 (2008).
  • Umemura T, Soga J, Hidaka T et al. Aging and hypertension are independent risk factors for reduced number of circulating endothelial progenitor cells. Am. J. Hypertens.21(11), 1203–1209 (2008).
  • Imanishi T, Hano T, Nishio I. Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress. J. Hypertens.23(1), 97–104 (2005).
  • Dimmeler S, Zeiher AM, Schneider MD. Unchain my heart: the scientific foundations of cardiac repair. J. Clin. Invest.115(3), 572–583 (2005).
  • Kukharchuk OL, Radchenko VV, Sipman BM et al. Effect of allotransplantation of embryonic pluripotent progenitor cells on dynamics of systemic arterial blood pressure in spontaneously hypertensive rats. Fiziol. Zh.49, 68–71 (2003).
  • Nagaya N, Kangawa K, Kanda M et al. Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells. Circulation108, 889–895 (2003).
  • Marsboom G, Janssens S. Endothelial progenitor cells: new perspectives and applications in cardiovascular therapies. Expert Rev. Cardiovasc. Ther.6(5), 687–701 (2008).
  • Wassmann S, Werner N, Czech T et al. Improvement of endothelial function by systemic transfusion of vascular progenitor cells. Circ. Res.99(8), e74–e83 (2006).
  • Gnecchi M, Zhang Z, Ni A, Dzau VJ. Paracrine mechanisms in adult stem cell signaling and therapy. Circ. Res.103(11), 1204–1219 (2008).
  • Watson T, Goon PK, Lip GY. Endothelial progenitor cells, endothelial dysfunction, inflammation, and oxidative stress in hypertension. Antioxid. Redox Signal.10(6), 1079–1088 (2008).
  • de Nigris F, Balestrieri ML, Williams-Ignarro S et al. Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways. J. Cardiovasc. Pharmacol.50(4), 424–433 (2007).
  • Chade AR, Zhu X, Lavi R et al. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation119(4), 547–557 (2009).
  • de Macedo Braga LM, Lacchini S, Schaan BD et al. In situ delivery of bone marrow cells and mesenchymal stem cells improves cardiovascular function in hypertensive rats submitted to myocardial infarction. J. Biomed. Sci.15(3), 365–374 (2008).
  • Braga LM, Rosa K, Rodrigues B et al. Systemic delivery of adult stem cells improves cardiac function in spontaneously hypertensive rats. Clin. Exp. Pharmacol. Physiol.35(2), 113–119 (2008).
  • Perry TE, Song M, Despres DJ et al. Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction. Cardiovasc. Res. DOI: 10.1093/cvr/cvp215 (2009) (Epub ahead of print).
  • Aicher A, Heeschen C, Mildner-Rihm C et al. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat. Med.9(11), 1370–1376 (2003).
  • Dias da Silva VJ, Machado MP, Rocha AM et al. Bone marrow stem/progenitor cells reduce arterial blood pressure and ameliorate endothelial dysfunction in spontaneously hypertensive rats. FASEB J. (Abstract) 19, 7439–7439 (2005).

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