48
Views
2
CrossRef citations to date
0
Altmetric
Review

Use of neuroimaging in acute stroke trials

&
Pages 885-895 | Published online: 09 Jan 2014

References

  • Di Carlo A, Launer LJ, Breteler MM et al. Frequency of stroke in Europe: a collaborative study of population-based cohorts. ILSA Working Group and the Neurologic Diseases in the Elderly Research Group. Italian Longitudinal Study on Aging. Neurology54(11 Suppl. 5), S28–S33 (2000).
  • Bejot Y, Benatru I, Rouaud O et al. Epidemiology of stroke in Europe: geographic and environmental differences. J. Neurol. Sci.262(1–2), 85–88 (2007).
  • Higashida RT, Furlan AJ, Roberts H et al. Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke34(8), e109–e137 (2003).
  • Hacke W, Kaste M, Fieschi C et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA274(13), 1017–1025 (1995).
  • Clark WM, Albers GW, Madden KP, Hamilton S. The rtPA (alteplase) 0- to 6-hour acute stroke trial, part A (A0276g): results of a double-blind, placebo-controlled, multicenter study. Thromblytic therapy in acute ischemic stroke study investigators. Stroke31(4), 811–816 (2000).
  • Hacke W, Kaste M, Bluhmki E et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N. Engl. J. Med.359(13), 1317–1329 (2008).
  • Schellinger PD, Fiebach JB, Hacke W. Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status. Stroke34(2), 575–583 (2003).
  • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med.333(24), 1581–1587 (1995).
  • Hacke W, Kaste M, Fieschi C et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European–Australasian Acute Stroke Study Investigators. Lancet352(9136), 1245–1251 (1998).
  • Grotta JC, Chiu D, Lu M et al. Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy. Stroke30(8), 1528–1533 (1999).
  • Barber PA, Demchuk AM, Zhang J, Buchan AM. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet355(9216), 1670–1674 (2000).
  • Pexman JH, Barber PA, Hill MD et al. Use of the Alberta stroke program early CT Score (ASPECTS) for assessing CT scans in patients with acute stroke. Am. J. Neuroradiol.22(8), 1534–1542 (2001).
  • Demchuk AM, Hill MD, Barber PA, Silver B, Patel SC, Levine SR. Importance of early ischemic computed tomography changes using ASPECTS in NINDS rtPA Stroke Study. Stroke36(10), 2110–2115 (2005).
  • Dzialowski I, Hill MD, Coutts SB et al. Extent of early ischemic changes on computed tomography (CT) before thrombolysis: prognostic value of the Alberta Stroke Program Early CT Score in ECASS II. Stroke37(4), 973–978 (2006).
  • Hill MD, Rowley HA, Adler F et al. Selection of acute ischemic stroke patients for intra-arterial thrombolysis with pro-urokinase by using ASPECTS. Stroke34(8), 1925–1931 (2003).
  • Messe SR, Kasner SE, Chalela JA et al. CT-NIHSS mismatch does not correlate with MRI diffusion–perfusion mismatch. Stroke38(7), 2079–2084 (2007)
  • Kohrmann M, Juttler E, Huttner HB, Nowe T, Schellinger PD. Acute stroke imaging for thrombolytic therapy – an update. Cerebrovasc. Dis.24(2–3), 161–169 (2007).
  • Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia – the ischemic penumbra. Stroke12(6), 723–725 (1985).
  • Read SJ, Hirano T, Abbott DF et al. The fate of hypoxic tissue on 18F-fluoromisonidazole positron emission tomography after ischemic stroke. Ann. Neurol.48(2), 228–235 (2000).
  • Maulaz A, Piechowski-Jozwiak B, Michel P, Bogousslavsky J. Selecting patients for early stroke treatment with penumbra images. Cerebrovasc. Dis.20(Suppl. 2), 19–24 (2005).
  • Warach S, Chien D, Li W, Ronthal M, Edelman RR. Fast magnetic resonance diffusion-weighted imaging of acute human stroke. Neurology42(9), 1717–1723 (1992).
  • Kidwell CS, Saver JL, Mattiello J et al. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology57(11), 2015–2021 (2001).
  • Kidwell CS, Saver JL, Mattiello J et al. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann. Neurol.47(4), 462–469 (2000).
  • Takasawa M, Jones PS, Guadagno JV et al. How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET. Stroke39, 870–877 (2008).
  • Ostergaard L, Weisskoff RM, Chesler DA, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: mathematical approach and statistical analysis. Magn. Reson. Med.36(5), 715–725 (1996).
  • Ostergaard L, Sorensen AG, Kwong KK, Weisskoff RM, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: experimental comparison and preliminary results. Magn. Reson. Med.36(5), 726–736 (1996).
  • Siemonsen S, Fitting T, Thomalla G et al. T2´ imaging predicts infarct growth beyond the acute diffusion-weighted imaging lesion in acute stroke. Radiology248(3), 979–986 (2008).
  • Schramm P, Schellinger PD, Fiebach JB et al. Comparison of CT and CT angiography source images with diffusion-weighted imaging in patients with acute stroke within 6 hours after onset. Stroke33(10), 2426–2432 (2002).
  • Koenig M, Klotz E, Luka B, Venderink DJ, Spittler JF, Heuser L. Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke. Radiology209(1), 85–93 (1998).
  • Wintermark M, Reichhart M, Thiran JP et al. Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients. Ann. Neurol.51(4), 417–432 (2002).
  • Sasaki M, Kudo K, Oikawa H. CT perfusion for acute stroke: current concepts on technical aspects and clinical applications. Int. Congr. Ser.1290, 30–36 (2006).
  • Wintermark M, Meuli R, Browaeys P et al. Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment. Neurology68(9), 694–697 (2007).
  • Heiss WD. Imaging the penumbra: the pathophysiologic basis for therapy of ischemic stroke. Presented at: 10th International Symposium on Thrombolysis and Acute Stroke Therapy. Budapest, Hungary, 21–23 September 2008.
  • Handschu R, Garling A, Heuschmann PU, Kolominsky-Rabas PL, Erbguth F, Neundorfer B. Acute stroke management in the local general hospital. Stroke32(4), 866–870 (2001).
  • Barber PA, Zhang J, Demchuk AM, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology56(8), 1015–1020 (2001).
  • Wintermark M, Albers GW, Alexandrov AV et al. Acute stroke imaging research roadmap. Stroke39(5), 1621–1628 (2008).
  • Wintermark M, Albers GW, Alexandrov AV et al. Acute stroke imaging research roadmap. AJNR Am. J. Neuroradiol.29(5), e23–e30 (2008).
  • Warach S. Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials. Curr. Control Trials Cardiovasc. Med.2, 38–44 (2001).
  • Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM. MR contrast due to intravascular magnetic susceptibility perturbations. Magn. Reson. Med.34(4), 555–566 (1995).
  • Fiehler J, Albers GW, Boulanger JM et al. Bleeding risk analysis in stroke imaging before thromboLysis (BRASIL): pooled analysis of T2*-weighted magnetic resonance imaging data from 570 patients. Stroke38(10), 2738–2744 (2007).
  • Latour LL, Kang DW, Ezzeddine MA, Chalela JA, Warach S. Early blood–brain barrier disruption in human focal brain ischemia. Ann. Neurol.56(4), 468–477 (2004).
  • Molina CA, Saver JL. Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke36(10), 2311–2320 (2005).
  • Ritzl A, Meisel S, Wittsack HJ et al. Development of brain infarct volume as assessed by magnetic resonance imaging (MRI): follow-up of diffusion-weighted MRI lesions. J. Magn. Reson. Imaging20(2), 201–207 (2004).
  • Albers GW, Thijs VN, Wechsler L et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann. Neurol.60(5), 508–517 (2006).
  • Davis SM, Donnan GA, Parsons MW et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol.7(4), 299–309 (2008).
  • Ribo M, Molina CA, Rovira A et al. Safety and efficacy of intravenous tissue plasminogen activator stroke treatment in the 3- to 6-hour window using multimodal transcranial Doppler/MRI selection protocol. Stroke36(3), 602–606 (2005).
  • Schellinger PD, Fiebach JB, Jansen O et al. Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann. Neurol.49(4), 460–469 (2001).
  • Hacke W, Albers G, Al-Rawi Y et al. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a Phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke36(1), 66–73 (2005).
  • Furlan AJ, Eyding D, Albers GW et al. Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke37(5), 1227–1231 (2006).
  • Kane I, Sandercock P, Wardlaw J. Magnetic resonance perfusion diffusion mismatch and thrombolysis in acute ischaemic stroke: a systematic review of the evidence to date. J. Neurol. Neurosurg. Psychiatry78(5), 485–491 (2007).
  • Kidwell CS, Alger JR, Saver JL. Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke35, 2662–2665 (2004).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.