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Perspective

Should atopy be assessed in elderly patients with respiratory symptoms suggestive of asthma?

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Pages 585-591 | Published online: 09 Jan 2014

References

  • Compston JE. Bone marrow and bone: a functional unit. J. Endocrinol.173, 387–394 (2002).
  • Gomez CR, Boehmer ED, Kovacs EJ. The aging innate immune system. Curr. Opin Immunol.17, 457–462 (2005).
  • Sansoni P, Vescovini R, Fagnoni F et al. The immune system in extreme longevity. Exp. Gerontol.43, 61–65 (2008).
  • Luscieti P, Hubschmid T, Cottier H, Hess MW, Sobin LH. Human lymph node morphology as a function of age and site. J. Clin. Pathol.33, 454–461 (1980).
  • Weksler ME, Szabo P. The effect of age on the B-cell repertoire. J. Clin. Immunol.20, 240–249 (2000).
  • Eaton SM, Burns EM, Kusser K, Randall TD, Haynes L. Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses. J. Exp. Med.200, 1613–1622 (2004).
  • Foy TM, Aruffo A, Bajorath J, Buhlmann JE, Noelle RJ. Immune regulation by CD40 and its ligand GP39. Annu. Rev. Immunol.14, 591–617 (1996).
  • Haynes L, Eaton SM. The effect of age on the cognate function of CD4+ T cells. Immunol. Rev.205, 220–228 (2005).
  • Sato H, Dobashi M. The distribution, immune complex trapping ability and morphology of follicular dendritic cells in popliteal lymph nodes of aged rats. Histol. Histopathol.13, 99–108 (1998).
  • Agrawal A, Agrawal S, Gupta S. Dendritic cells in human aging. Exp. Gerontol.42, 421–426 (2007).
  • Gazit R, Weissman IL, Rossi DJ. Hematopoietic stem cells and the aging hematopoietic system. Semin. Hematol.45, 218–224 (2008).
  • Ibs KH, Rink L. The immune system in aging. Z. Gerontol. Geriatr.34, 480–485 (2001).
  • Enright PL, McClelland RL, Newman AB, Gottlieb DJ, Lebowitz MD. Underdiagnosis and undertreatment of asthma in the elderly. Cardiovascular Health Study Research Group. Chest116, 603–613 (1999).
  • Parameswaran, K, Hildreth AJ, Chadha D, Keaney NP, Taylor IK, Bansal SK. Asthma in the elderly: underperceived, underdiagnosed and undertreated; a community survey. Respir. Med.92, 573–577 (1998).
  • Adams RJ, Wilson DH, Appleton S et al. Underdiagnosed asthma in South Australia. Thorax58, 846–850 (2003).
  • Mitsunobu F, Mifune T, Hosaki Y et al. IgE-mediated and age-related bronchial hyperresponsiveness in patients with asthma. Relationship to family history of the disease. Age Ageing29, 215–220 (2000).
  • Parker DR, O’Connor GT, Sparrow D, Segal MR, Weiss ST. The relationship of nonspecific airway responsiveness and atopy to the rate of decline of lung function. The Normative Aging Study. Am. Rev. Respir. Dis.141, 589–594 (1990).
  • Witt C, Stuckey MS, Woolcock AJ, Dawkins RL. Positive allergy prick tests associated with bronchial histamine responsiveness in an unselected population. J. Allergy Clin. Immunol.77, 698–702 (1986).
  • Scichilone N, Messina M, Battaglia S, Catalano F, Bellia V. Airway hyperresponsiveness in the elderly: prevalence and clinical implications. Eur. Respir. J.25, 364–375 (2005).
  • Choy DK, Hui DS, Li ST et al. Prevalence of wheeze, bronchial hyper-responsiveness and asthma in the elderly Chinese. Clin. Exp. Allergy32, 702–707 (2002).
  • Horsley JR, Sterling IJ, Waters WE, Howell JB. How common is increased airway reactivity amongst the elderly? Gerontology39, 38–48 (1993).
  • Sparrow D, O’Connor GT, Rosner B, Segal MR, Weiss ST. The influence of age and level of pulmonary function on nonspecific airway responsiveness. The Normative Aging Study. Am. Rev. Respir. Dis.143, 978–982 (1991).
  • Sparrow D, O’Connor GT, Rosner B, Weiss ST. Predictors of longitudinal change in methacholine airway responsiveness among middle-aged and older men: the Normative Aging Study. Am. J. Respir. Crit. Care Med.149, 376–381 (1994).
  • Verbeken EK, Cauberghs M, Mertens I, Clement J, Lauweryns JM, Van de Woestijne KP. The senile lung. Comparison with normal and emphysematous lungs. 2. Functional aspects. Chest101, 800–809 (1992).
  • Verbeken EK, Cauberghs M, Mertens I, Clement J, Lauweryns JM, Van de Woestijne KP. The senile lung. Comparison with normal and emphysematous lungs. 1. Structural aspects. Chest101, 793–799 (1992).
  • Ohman JL Jr, Sparrow D, MacDonald MR. New onset wheezing in an older male population: evidence of allergen sensitization in a longitudinal study. Results of the normative aging study. J. Allergy Clin. Immunol.91, 752–757 (1993).
  • Hospers JJ, Postma DS, Rijcken B, Weiss ST, Schouten JP. Histamine airway hyper-responsiveness and mortality from chronic obstructive pulmonary disease: a cohort study. Lancet356, 1313–1317 (2000).
  • Bellia V, Battaglia S, Catalano F et al. Aging and disability affect misdiagnosis of COPD in elderly asthmatics: the SARA study. Chest123, 1066–1072 (2003).
  • Adams RJ, Wilson DH, Appleton S et al. Underdiagnosed asthma in South Australia. Thorax58, 846–850 (2003).
  • Kitch BT, Levy BD, Fanta CH. Late onset asthma: epidemiology, diagnosis and treatment. Drugs Aging17, 385–397 (2000).
  • Bauer BA, Reed CE, Yunginger JW, Wollan PC, Silverstein MD. Incidence and outcomes of asthma in the elderly. A population-based study in Rochester, Minnesota. Chest111, 303–310 (1997).
  • Ariano R, Panzani RC, Augeri G. Late onset asthma clinical and immunological data: importance of allergy. J. Investig. Allergol. Clin. Immunol.8, 35–41 (1998).
  • Burrows B, Lebowitz MD, Barbee RA, Cline MG. Findings before diagnoses of asthma among the elderly in a longitudinal study of a general population sample. J. Allergy Clin. Immunol.88, 870–877 (1991).
  • Parameswaran K, Hildreth AJ, Taylor IK, Keaney NP, Bansal SK. Predictors of asthma severity in the elderly: results of a community survey in Northeast England. J. Asthma36, 613–618 (1999).
  • Mediaty A, Neuber K. Total and specific serum IgE decreases with age in patients with allergic rhinitis, asthma and insect allergy but not in patients with atopic dermatitis. Immun. Ageing2(1), 9 (2005).
  • Braman SS. Growing old with asthma: what are the changes and challenges? Expert Rev. Respir. Med.4, 239–248 (2010).
  • Clough JB, Williams JD, Holgate ST. Effect of atopy on the natural history of symptoms, peak expiratory flow, and bronchial responsiveness in 7- and 8-year-old children with cough and wheeze. A 12-month longitudinal study [published errarum appears in Am. Rev. Respir. Dis. 1992 Aug; 146(2):540]. Am. Rev. Respir. Dis.143, 755–760 (1991).
  • Asero R. Birch and ragweed pollinosis north of Milan: a model to investigate the effects of exposure to ‘new’ airborne allergens. Allergy57, 1063–1066 (2002).
  • Litonjua AA, Sparrow D, Weiss ST, O’Connor GT, Long AA, Ohman JL Jr. Sensitization to cat allergen is associated with asthma in older men and predicts new-onset airway hyperresponsiveness. The Normative Aging Study. Am. J. Respir. Crit. Care Med.156, 23–27 (1997).
  • Scichilone N, Marchese R, Catalano F, Togias A, Vignola AM, Bellia V. The bronchodilatory effect of deep inspiration diminishes with aging. Respir. Med.98, 838–843 (2004).
  • Kizkin O, Turker G, Hacievliyagil SS, Gunen H. Asthma, age, and early reversibility testing. J. Asthma40, 317–321 (2003).
  • Sin BA, Akkoca O, Saryal S, Oner F, Misirligil Z. Differences between asthma and COPD in the elderly. J. Investig. Allergol. Clin. Immunol.16, 44–50 (2006).
  • Bousquet J, Clark TJ, Hurd S et al. GINA guidelines on asthma and beyond. Allergy62, 102–112 (2007).
  • Togias A. Rhinitis and asthma: evidence for respiratory system integration. J. Allergy Clin. Immunol.111, 1171–1183 (2003).
  • Kim HY, So YK, Dhong HJ et al. Prevalence of lower airway diseases in patients with chronic rhinosinusitis. Acta Otolaryngol Suppl.558, 110–114 (2007).
  • Oguzulgen IK, Kervan F, Ozis T, Turktas H. The impact of bronchiectasis in clinical presentation of asthma. South Med. J.100, 468–471 (2007).
  • Cox L, Cohn JR. Duration of allergen immunotherapy in respiratory allergy: when is enough, enough? Ann. Allergy Asthma Immunol.98, 416–426 (2007).
  • Asero R. Efficacy of injection immunotherapy with ragweed and birch pollen in elderly patients. Int. Arch. Allergy Immunol.135, 332–335 (2004).
  • Strunk RC, Bloomberg GR. Omalizumab for asthma N. Engl. J. Med.354, 2689–2695 (2006).
  • Maykut RJ, Kianifard F, Geba GP. Response of older patients with IgE-mediated asthma to omalizumab: a pooled analysis. J. Asthma45, 173–181 (2008).

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