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Expert Review of Respiratory Medicine Volume 4, 2010 - Issue 5
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Key Paper Evaluation

Probiotics for the prevention of ventilator-associated pneumonia

Matthew E Falagas Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece; Department of Medicine, Henry Dunant Hospital, Athens, Greece. [email protected]; Department of Medicine, Tufts University School of Medicine, Boston, MA, USA; Department of Medicine, Henry Dunant Hospital, Athens, Greece. [email protected]
,
Ioanna P Korbila Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece; Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
&
Drosos E Karageorgopoulos Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece; Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
Pages 567-571 | Published online: 09 Jan 2014

References

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  • Coffin SE, Klompas M, Classen D et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect. Control Hosp. Epidemiol.29(Suppl. 1), S31–S40 (2008).
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  • de Smet AM, Kluytmans JA, Cooper BS et al. Decontamination of the digestive tract and oropharynx in ICU patients. N. Engl. J. Med.360(1), 20–31 (2009).
  • Besselink MG, van Santvoort HC, Buskens E et al. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet371(9613), 651–659 (2008).
  • Cohen SH, Gerding DN, Johnson S et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect. Control Hosp. Epidemiol.31, 431–455 (2010).
  • Falagas ME, Kouranos VD, Michalopoulos A, Rodopoulou SP, Athanasoulia AP, Karageorgopoulos DE. Inadequate statistical power of published comparative cohort studies on ventilator-associated pneumonia to detect mortality differences. Clin. Infect. Dis.50(4), 468–472 (2010).
  • Siempos II, Vardakas KZ, Kyriakopoulos CE, Ntaidou TK, Falagas ME. Predictors of mortality in adult patients with ventilator-associated pneumonia: a meta-analysis. Shock33(6), 590–601 (2010).

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