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Editorial

Triple inhalers for obstructive airways disease: will they be useful?

Pages 297-300 | Published online: 09 Jan 2014

References

  • Nannini L, Cates C, Lasserson T et al. Combined corticosteroid and long-acting β-agonist in one inhaler versus long-acting β-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev.4, CD006829 (2007).
  • Calverley PM, Anderson JA, Celli B et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N. Engl. J. Med.356, 775–789 (2007).
  • Szafranski W, Cukier A, Ramirez A et al. Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur. Respir. J.21, 74–81 (2003).
  • Calverley PM, Kuna P, Monso E et al. Beclomethasone/formoterol in the management of COPD: a randomised controlled trial. Respir. Med.104, 1858–1868 (2010).
  • Yang IA, Fong KM, Sim EH et al. Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane Database Syst. Rev.2, CD002991 (2007).
  • Barnes PJ. Inhaled corticosteroids in COPD: a controversy. Respiration80, 89–95 (2010).
  • Suissa S, Ernst P, Vandemheen KL et al. Methodological issues in therapeutic trials of COPD. Eur. Respir. J.31, 927–933 (2008).
  • Suissa S, Barnes PJ. Inhaled corticosteroids in COPD: the case against. Eur. Respir. J.34, 13–16 (2009).
  • Rabe KF, Hurd S, Anzueto A et al. Global strategy for the diagnosis, management, and prevention of COPD – 2006 Update. Am. J. Respir. Crit. Care Med.176, 532–555 (2007).
  • Drummond MB, Dasenbrook EC, Pitz MW et al. Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis. JAMA300, 2407–2416 (2008).
  • Suissa S, Kezouh A, Ernst P. Inhaled corticosteroids and the risks of diabetes onset and progression. Am. J. Med.123, 1001–1006 (2010).
  • Singh S, Loke YK. An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease. Int. J. Chron. Obstruct. Pulmon. Dis.5, 189–195 (2010).
  • Tashkin DP, Celli B, Senn S et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N. Engl. J. Med.359, 1543–1554 (2008).
  • Decramer M, Celli B, Kesten S et al. Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial. Lancet374, 1171–1178 (2009).
  • Wedzicha JA, Calverley PM, Seemungal TA et al. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am. J. Respir. Crit. Care Med.177, 19–26 (2008).
  • Welsh EJ, Cates CJ, Poole P. Combination inhaled steroid and long-acting β2-agonist versus tiotropium for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev.3, CD007891 (2010).
  • Singh D, Brooks J, Hagan G et al. Superiority of ‘triple’ therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD. Thorax63, 592–598 (2008).
  • Cazzola M, Ando F, Santus P et al. A pilot study to assess the effects of combining fluticasone propionate/salmeterol and tiotropium on the airflow obstruction of patients with severe-to-very severe COPD. Pulm. Pharmacol. Ther.20, 556–561 (2007).
  • Aaron SD, Vandemheen KL, Fergusson D et al. Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial. Ann. Intern. Med.146, 545–555 (2007).
  • Karner C, Cates CJ. Combination inhaled steroid and long-acting β(2)-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev.3, CD008532 (2011).
  • Cazzola M, Matera MG. Emerging inhaled bronchodilators: an update. Eur. Respir. J.34, 757–769 (2009).
  • Korn S, Kerwin E, Atis S et al. Indacaterol once-daily provides superior efficacy to salmeterol twice-daily in COPD: a 12-week study. Respir. Med.105(5), 719–726 (2011).
  • Barnes PJ, Pocock SJ, Magnussen H et al. Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design. Pulm. Pharmacol. Ther.23, 165–171 (2010).
  • Vogelmeier C, Ramos-Barbon D, Jack D et al. Indacaterol provides 24-hour bronchodilation in COPD: a placebo-controlled blinded comparison with tiotropium. Respir. Res.11, 135 (2010).
  • Chapman KR, Rennard SI, Dogra A et al. Long-term Safety and Efficacy of Indacaterol, a Novel Long-acting {β}2-Agonist, in Subjects with COPD: a Randomized, Placebo-controlled Study. Chest DOI: 10.1378/chest.10-1830 (2011) (Epub ahead of print).
  • van Noord JA, Aumann JL, Janssens E et al. Effects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. Chest129, 509–517 (2006).
  • van Noord JA, Aumann JL, Janssens E et al. Combining tiotropium and salmeterol in COPD: effects on airflow obstruction and symptoms. Respir. Med.104, 995–1004 (2010).
  • Tashkin DP, Pearle J, Iezzoni D et al. Formoterol and tiotropium compared with tiotropium alone for treatment of COPD. COPD6, 17–25 (2009).
  • Cazzola M. Aclidinium bromide, a novel long-acting muscarinic M3 antagonist for the treatment of COPD. Curr. Opin. Investig. Drugs10, 482–490 (2009).
  • Gibson PG, Powell H, Ducharme FM. Differential effects of maintenance long-acting β-agonist and inhaled corticosteroid on asthma control and asthma exacerbations. J. Allergy Clin. Immunol.119, 344–350 (2007).
  • Ducharme FM, Ni CM, Greenstone I et al. Addition of long-acting β2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children. Cochrane Database Syst. Rev.5, CD005535 (2010).
  • Edwards SJ, von Maltzahn R, Naya IP et al. Budesonide/formoterol for maintenance and reliever therapy of asthma: a meta analysis of randomised controlled trials. Int. J. Clin. Pract.64, 619–627 (2010).
  • Magnussen H, Bugnas B, van Noord J et al. Improvements with tiotropium in COPD patients with concomitant asthma. Respir. Med.102, 50–56 (2008).
  • Park HW, Yang MS, Park CS et al. Additive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response. Allergy64, 778–783 (2009).
  • Israel E, Chinchilli VM, Ford JG et al. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet364, 1505–1512 (2004).
  • Peters SP, Kunselman SJ, Icitovic N et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N. Engl. J. Med.363, 1715–1726 (2010).
  • Lavorini F, Magnan A, Christophe DJ et al. Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD. Respir. Med.102, 593–604 (2007).
  • Pitchayajittipong C, Shur J, Price R. Engineering of crystalline combination inhalation particles of a long-acting β2-agonist and a corticosteroid. Pharm. Res.26, 2657–2666 (2009).
  • Ray NC, Alcaraz L. Muscarinic antagonist-β-adrenergic agonist dual pharmacology molecules as bronchodilators: a patent review. Expert Opin. Ther. Pat.19, 1–12 (2009).
  • Barnes PJ. Emerging pharmacotherapies for COPD. Chest134, 1278–1286 (2008).

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