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Future Science OA Volume 5, 2019 - Issue 8
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Research Article

Downregulation of RBBP6 Variant 1 During Arsenic Trioxide-Mediated Cell Cycle Arrest and Curcumin-Induced Apoptosis in MCF-7 Breast Cancer Cells

Lilian Makgoo1 Department of Biochemistry, Microbiology, & Biotechnology, University of Limpopo, Private Bag x1106, Sovenga, 0727, Polokwane, South Africa
,
Kagiso Laka1 Department of Biochemistry, Microbiology, & Biotechnology, University of Limpopo, Private Bag x1106, Sovenga, 0727, Polokwane, South Africa
&
Zukile Mbita1 Department of Biochemistry, Microbiology, & Biotechnology, University of Limpopo, Private Bag x1106, Sovenga, 0727, Polokwane, South AfricaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3179-8169
ORCID Icon
Article: FSO409 | Received 03 Apr 2019, Accepted 07 Jun 2019, Published online: 30 Jul 2019

References

  • SiegelRL , MillerKD , JemalA. Cancer statistics 2015. CA Cancer J. Clin.65(1), 5–29 (2015).
  • DiLeo A , CuriglianoG , DiérasVet al.New approaches for improving outcomes in breast cancer in Europe. Breast24(4), 321–330 (2015).
  • LiL , DengB , XingGet al.PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc. Natl Acad. Sci. USA104(19), 7951–7956 (2007).
  • MbitaZ , MeyerM , SkepuA , HosieM , ReesJ , DlaminiZ. De-regulation of the RBBP6 isoform 3/DWNN in human cancers. Mol. Cell Biochem.362(1–2), 249–262 (2012).
  • MotadiLR , BhoolaKD , DlaminiZ. Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer. Immunobiology216(10), 1065–1073 (2012).
  • NtwasaM , NwekeE , CajeeUF. The retinoblastoma binding protein 6 family is essential for embryonic development and carcinogenesis. J. Cancer Res. Forecast1(1), 2002 (2018).
  • NtwasaM. Retinoblastoma binding protein 6, another p53 monitor. Trends Cancer2(11), 635–637 (2016).
  • GaoS , ScottRE. P2P‐R protein overexpression restricts mitotic progression at prometaphase and promotes mitotic apoptosis. J. Cell. Physiol.193(2), 199–207 (2002).
  • BajG , ArnulfoA , DeaglioSet al.Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects. Breast Cancer Res. Treat.73(1), 61–73 (2002).
  • ChoudhuriT , PalS , AgwarwalML , DasT , SaG. Curcumin induces apoptosis in human breast cancer cells through p53‐dependent Bax induction. FEBS Lett.512(1–3), 334–340 (2012).
  • BaeS , JeongHJ , ChaHJet al.The hypoxia-mimetic agent cobalt chloride induces cell cycle arrest and alters gene expression in U266 multiple myeloma cells. Int. J. Mol. Med.30(5), 1180–1186 (2012).
  • FoghsgaardL , WissingD , MauchDet al.Cathepsin B acts as a dominant execution protease in tumour cell apoptosis induced by tumour necrosis factor. J. Cell Biol.153(5), 999–1010 (2001).
  • PughDJ , EisoAB , FaroA , LutyaPT , HoffmannE , ReesDJG. DWNN, a novel ubiquitin-like domain, implicates RBBP6 in mRNA processing and ubiquitin-like pathways. BMC Struct. Biol.6(1), 1 (2006).
  • ChibiM , MeyerM , SkepuA , ReesDJG , Moolman-SmookJC , PughDJ. RBBP6 interacts with multifunctional protein YB-1 through its RING finger domain, leading to ubiquitination and proteosomal degradation of YB-1. J. Mol. Biol.384(4), 908–916 (2008).
  • ChenJ , TangH , WuZ , ZhouC , JiangT , XueYet al.Overexpression of RBBP6, alone or combined with mutant TP53, is predictive of poor prognosis in colon cancer. PLoS ONE8(6), e66524 (2013).
  • SinghJ , MnickamP , ShmoishMet al.Annotation of androgen dependence to human prostate cancer-associated genes by microarray analysis of mouse prostate. Cancer Lett.237(2), 298–304 (2006).
  • YoshitakeY , NakatsuraT , MonjiMet al.Proliferation potential-related protein, an ideal oesophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis. Clin. Cancer Res.10, 6437–6448 (2004).
  • JiangL , WangL , ChenLet al.As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases. Int. J. Clin. Exp. Med.8(2), 2190 (2015).
  • GaoYH , ZhangHP , YangSMet al.Inactivation of Akt by arsenic trioxide induces cell death via mitochondrial-mediated apoptotic signalling in SGC-7901 human gastric cancer cells. Oncol. Rep.31(4), 1645–1652 (2014).
  • ChunYJ , ParkIC , ParkMet al.Enhancement of radiation response in human cervical cancer cells in vitro and in vivo by arsenic trioxide (As2O3). FEBS Lett.519(1–3), 195–200 (2002).
  • KanzawaT , KondoY , ItoH , KondoS , GermanoI. Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. Cancer Res.63(9), 2103–2108 (2003).
  • WangY , ZhangY , YangLet al.Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels. Exp. Ther. Med.2(3), 481–486 (2011).
  • StevensJJ , GrahamB , DugoE , Berhaneselassie-SumnerB , NdebeleK , TchounwouPB. Arsenic trioxide induces apoptosis via specific signaling pathways in HT-29 colon cancer cells. J. Cancer Sci. Ther.9(1), 298 (2017).
  • JänickeRU. MCF-7 breast carcinoma cells do not express caspase-3. Breast Cancer Res. Treat.117(1), 219–221 (2009).
  • ParamitaD , WisnubrotoJDP. Effect of methylglyoxal on reactive oxygen species, KI-67, and caspase-3 expression in MCF-7 cells. Exp. Mol. Pathol.105(1), 76–80 (2018).

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