2,163
Views
23
CrossRef citations to date
0
Altmetric
Special Report

Vinpocetine is the Forthcoming Adjuvant Agent in the Management of COVID-19

, , ORCID Icon &
Article: FSO797 | Received 18 Aug 2021, Accepted 23 Mar 2022, Published online: 14 Apr 2022

References

  • Al-kuraishyHM , Al-GareebAI , AlbuhadillyAK. Vinpocetine and pyritinol: a new model for blood rheological modulation in cerebrovascular disorders a randomized controlled clinical study. Biomed. Res. Int.2014, 324307 (2014).
  • Al-KuraishyHM , Al-GareebAI , NajiMT , Al-MamorryF. Role of vinpocetine in ischemic stroke and poststroke outcomes: a critical review. Brain Circ.6(1), 1 (2020).
  • SchermulyRT , PullamsettiSS , KwapiszewskaGet al.Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy. Circulation115(17), 2331–2339 (2007).
  • JeonKI , XuX , AizawaTet al.Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proc. Natl Acad. Sci.107(21), 9795–9800 (2010).
  • WuLR , LiuL , XiongXYet al.Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling. Oncotarget8(46), 80315 (2017).
  • BatihaGE , Al-GareebAI , QustiSet al.Common NLRP3 inflammasome inhibitors and COVID-19: divide and conquer. Sci. Afr.e01084Doi: 10.1016/j.sciaf.2021.e01084 (2021) ( Epub ahead of print).
  • Al-KuraishyHM , Al-GareebAI , AlblihedM , Cruz-MartinsN , BatihaGE. COVID-19 and risk of acute ischemic stroke and acute lung injury in patients with Type II diabetes mellitus: the anti-inflammatory role of metformin. Front. Med. (Lausanne)8, 644295 (2021).
  • KircheisR , HaasbachE , LuefteneggerD , HeykenWT , OckerM , PlanzO. NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients. Front. Immunol.11, 598444 (2020).
  • MoubarakM , KasoziKI , HettaHFet al.The rise of SARS-CoV-2 variants and the role of convalescent plasma therapy for management of infections. Life (Basel)11(8), 734 (2021).
  • HariharanA , HakeemAR , RadhakrishnanS , ReddyMS , RelaM. The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients. Inflammopharmacology29(1), 91–100 (2021).
  • YongshunYE , LiuH. Vinpocetine injection attenuates lipopolysaccharide-induced acute lung injury in rats. Chin. J. Pathophysiology33(7), 1278–1282 (2017).
  • LugnierC , Al-KuraishyHM , RousseauE. PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in COVID-19 and cigarette smoking. Biochem. Pharmacol.185, 114431 (2021).
  • Al-kuraishyHM , Al-GareebAI , FaidahH , Al-MaiahyTJ , Cruz-MartinsN , BatihaGE. The looming effects of estrogen in COVID-19: a rocky rollout. Front. Nutr.8, 649128 (2021).
  • Al-KuraishyHM , Al-GareebAI , Al-HussaniyHA , Al-HarcanNA , AlexiouA , BatihaGE. Neutrophil extracellular traps (NETs) and COVID-19: a new frontiers for therapeutic modality. Int. Immunopharmacol.104, 108516 (2022).
  • Al-KuraishyHM , Al-GareebAI , AlqarniM , Cruz-MartinsN , El-SaberBatiha G. Pleiotropic effects of tetracyclines in the management of COVID-19: emerging perspectives. Front. Pharmacol.12, 642822 (2021).
  • Al-KuraishyHM , Al-GareebAI , QustyN , Cruz-MartinsN , BatihaGE. Sequential doxycycline and colchicine combination therapy in COVID-19: the salutary effects. Pulm. Pharmacol. Ther.67, 102008 (2021).
  • LiuRT , WangA , ToEet al.Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells. Exp. Eye Res.127, 49–58 (2014).
  • HanD , WangJ , WenL , SunM , LiuH , GaoY. Vinpocetine attenuates ischemic stroke through inhibiting NLRP3 inflammasome expression in mice. J. Cardiovasc. Pharmacol.77(2), 208–216 (2020).
  • Al-KuraishyHM , Al-GareebAI , Al-NamiMS. Vinpocetine improves oxidative stress and pro-inflammatory mediators in acute kidney injury. Int. J. Prev. Med.10, 142 (2019).
  • SchönrichG , RafteryMJ , SamstagY. Devilishly radical NETwork in COVID-19: oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression. Adv. Biol. Regul.77, 100741 (2020).
  • BatihaGE , AwadDA , AlgammalAMet al.Dairy-derived and egg white proteins in enhancing immune system against COVID-19. Front. Nutr.8, 629440 (2021).
  • Al-KuraishyHM , Al-GareebAI , AlblihedM , GuerreiroSG , Cruz-MartinsN , BatihaGE. COVID-19 in relation to hyperglycemia and diabetes mellitus. Front. Cardiovasc. Med.8, 644095 (2021).
  • Ruiz-MiyazawaKW , Pinho-RibeiroFA , ZarpelonACet al.Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB. Chem. Biol. Interact.237, 9–17 (2015).
  • Al-KuraishyHM , Al-GareebAI , QustyN , AlexiouA , BatihaGE. Impact of sitagliptin in non-diabetic COVID-19 patients. Curr. Mol. Pharmacol. doi:10.2174/1874467214666210902115650 (2021) ( Epub ahead of print).
  • BatihaGE. Cyclosporine attenuates COVID-19: ensnare or victory. Ann. Clin. Med. Case Rep.7(4), 1–8 (2021).
  • Al-KuraishyHM , Al-GareebAI , AlkazmiL , AlexiouA , BatihaGE. Levamisole therapy in COVID-19. Viral Immunol.12, 1–14 (2021).
  • O'DonoghueML , GlaserR , CavenderMAet al.Effect of losmapimod on cardiovascular outcomes in patients hospitalized with acute myocardial infarction: a randomized clinical trial. JAMA315(15), 1591–1599 (2016).
  • ChristieJD , VaslefS , ChangPKet al.A randomized dose-escalation study of the safety and anti-inflammatory activity of the p38 mitogen-activated protein kinase inhibitor dilmapimod in severe trauma subjects at risk for acute respiratory distress syndrome. Crit. Care Med.43(9), 1859–1869 (2015).
  • GaoR , FangQ , ZhangXet al.R5 HIV-1 gp120 activates p38 MAPK to induce rat cardiomyocyte injury by the CCR5 coreceptor. Pathobiology86(5–6), 274–284 (2019).
  • LiD , RenW , JiangZ , ZhuL. Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury. Mol. Med. Rep.18(5), 4399–4409 (2018).
  • WangK , WenL , PengWet al.Vinpocetine attenuates neointimal hyperplasia in diabetic rat carotid arteries after balloon injury. PloS ONE9(5), e96894 (2014).
  • LeeJY , KomatsuK , LeeBCet al.Vinpocetine inhibits streptococcus pneumoniae – induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media. J. Immunol.194(12), 5990–5998 (2015).
  • Al-KuraishyHM , Al-GareebAI , Al-NiemiMS , Al-BuhadilyAK , Al-HarchanNA , LugnierC. COVID-19 and phosphodiesterase enzyme type 5 inhibitors. J. Microsc. Ultrastruct.8(4), 141 (2020).
  • IsidoriAM , GiannettaE , PofiRet al.Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project. Andrology9(1), 33–38 (2021).
  • SegarraV , CrespoMI , PujolFet al.Phosphodiesterase inhibitory properties of losartan. Design and synthesis of new lead compounds. Bioorg. Med. Chem. Lett.8(5), 505–510 (1998).
  • DewanjeeS , VallamkonduJ , KalraRS , PuvvadaN , KandimallaR , ReddyPH. Emerging COVID-19 neurological manifestations: present outlook and potential neurological challenges in COVID-19 pandemic. Mol. Neurobiol.58(9), 4694–4715 (2021).
  • GolovachevaVA , TabeevaGR , KuznetsovIV. Cognitive impairment in COVID-19: associations, pathogenesis and treatment questions. Neurol. Neuropsychiatr. Psychosomat.13(2), 123–129 (2021).
  • Alonso-LanaS , MarquiéM , RuizA , BoadaM. Cognitive and neuropsychiatric manifestations of COVID-19 and effects on elderly individuals with dementia. Front. Aging Neurosci.12, 588872 (2020).
  • MaglioneTJ , AboymeA , GhoshBD , BhattiS , KostisWJ. Electrical storm in a febrile patient with Brugada syndrome and COVID-19 infection. HeartRhythm Case Rep.6(10), 676 (2020).
  • PrioriSG , WildeAA , HorieMet al.HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm10(12), 1932–1963 (2013).
  • ZhangC , YanC. Updates of recent vinpocetine research in treating cardiovascular diseases. J. Cell. Immunol.2(5), 211 (2020).
  • ShiS , QinM , ShenBet al.Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol.5(7), 802–810 (2020).
  • ZhangYS , LiJD , YanC. An update on vinpocetine: new discoveries and clinical implications. Eur. J. Pharmacol.819, 30–44 (2018).
  • FeherG , CsecseiP , PappJet al.The role of adjuvant vinpocetine therapy in aspirin-treated cerebrovascular patients. J. Cardiol. Ther.7(1), 942–945 (2020).
  • CaiY , KnightWE , GuoS , LiJD , KnightPA , YanC. Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. J. Pharmacol. Exp. Ther.343(2), 479–488 (2012).
  • KoupenovaM. Potential role of platelets in COVID-19: implications for thrombosis. Res. Pract. Thromb. Haemost.4(5), 737–740 (2020).
  • ZuoY , YalavarthiS , ShiHet al.Neutrophil extracellular traps in COVID-19. JCI Insight5(11), e138999 (2020).
  • JoobB , WiwanitkitV. Blood viscosity of COVID-19 patient: a preliminary report. Am. J. Blood Res.11(1), 93–95 (2021).
  • FeherG , KoltaiK , KesmarkyGet al.Effect of parenteral or oral vinpocetine on the hemorheological parameters of patients with chronic cerebrovascular diseases. Phytomedicine16(2–3), 111–117 (2009).
  • KimD , RybalkinSD , PiXet al.Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance. Circulation104(19), 2338–2343 (2001).