References
- WHO. World malaria report (2022). www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2022
- TrivediS , ChakravartyA. Neurological complications of malaria. Curr. Neurol. Neurosci. Rep.22(8), 499–513 (2022).
- MaN , ZhangZ , LiaoF , JiangT , TuY. The birth of artemisinin. Pharmacol. Ther.216, 107658 (2020).
- KapishnikovS , HempelmannE , ElbaumM , Als-NielsenJ , LeiserowitzL. Malaria pigment crystals: the Achilles' heel of the malaria parasite. Chem. Med. Chem.16(10), 1515–1532 (2021).
- VallochiAL , TeixeiraL , OliveiraKDS , Maya-MonteiroCM , BozzaPT. Lipid droplet, a key player in host-parasite interactions. Front. Immunol.9, 1022 (2018).
- KimuraT , TakabatakeY , TakahashiA , IsakaY. Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res.73(1), 3–7 (2013).
- GaoJ , TianZ , YangX. Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies. Biosci. Trends14(1), 72–73 (2020).
- BrayPG , MartinRE , TilleyL , WardSA , KirkK , FidockDA. Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance. Mol. Microbiol.56(2), 323–333 (2005).
- WardKE , FidockDA , BridgfordJL. Plasmodium falciparum resistance to artemisinin-based combination therapies. Curr. Opin. Microbiol.69, 102193 (2022).
- SchrezenmeierE , DörnerT. Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology. Nat. Rev. Rheumatol.16(3), 155–166 (2020).
- Al-BariMAA. Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases. J. Antimicrob. Chemother.70(6), 1608–1621 (2015).
- EpsteinJE , PaolinoKM , RichieTLet al.Protection against Plasmodium falciparum malaria by PfSPZ Vaccine. JCI Insight2(1), e89154 (2017).
- SirimaSB , OuédraogoA , TionoABet al.A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria. Sci. Transl. Med.14(674), eabj3776 (2022).
- DuffyPE. Transmission-blocking vaccines: harnessing herd immunity for malaria elimination. Expert Rev. Vac.20(2), 185–198 (2021).
- CarolinoK , WinzelerEA. The antimalarial resistome-finding new drug targets and their modes of action. Curr. Opin. Microbiol.57, 49–55 (2020).
- SinghL , SinghK. Ivermectin: a promising therapeutic for fighting malaria. Current status and perspective. J. Med. Chem.64(14), 9711–9731 (2021).
- TouzeJE , FourcadeL , PradinesB , HovetteP , PauleP , HenoP. Mechanism of action of antimalarials. Value of combined atovaquone/proguanil. Med. Trop.62(3), 219–224 (2002).
- ThompsonAJ , LummisSCR. Antimalarial drugs inhibit human 5-HT3 and GABAA but not GABAC receptors. Brit. J. Pharmacol.153(8), 1686–1696 (2008).