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Review

Protective potential of mesenchymal stem cells against COVID-19 during pregnancy

ORCID Icon, ORCID Icon, ORCID Icon, , & ORCID Icon
Article: FSO924 | Received 31 Aug 2023, Accepted 17 Oct 2023, Published online: 20 May 2024

References

  • Huang C, Wang Y, Li X et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395(10223), 497–506 (2020).
  • Nadeem MS, Zamzami MA, Choudhry H et al. Origin, potential therapeutic targets and treatment for coronavirus disease (COVID-19). Pathogens 9(4), 307 (2020).
  • Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol 17(3), 181–192 (2019).
  • Guan W-J, Ni Z-Y, Hu Y et al. Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv doi: 10.1101/2020.02.06.20020974 (2020) ( Epub ahead of print).
  • Lauer SA, Grantz KH, Bi Q et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann. Intern. Med. 172(9), 577–582 (2020).
  • Munster VJ, Koopmans M, van Doremalen N, van Riel D, de Wit E. A novel coronavirus emerging in china - key questions for impact assessment. N. Engl. J. Med. 382(8), 692–694 (2020).
  • Shi L, Yuan X, Yao W et al. Human mesenchymal stem cells treatment for severe COVID-19: 1-year follow-up results of a randomized, double-blind, placebo-controlled trial. EBioMedicine 75, 103789 (2022).
  • Karakas N, Ucuncuoglu S, Uludag D, Karaoglan BS, Shah K, Ozturk G. Mesenchymal stem cell-based COVID-19 therapy: bioengineering perspectives. Cells 11(3), 465 (2022).
  • Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet 395(10223), 470–473 (2020).
  • Gentile P, Sterodimas A, Pizzicannella J, Calabrese C, Garcovich S. Research progress on mesenchymal stem cells (MSCs), adipose-derived mesenchymal stem cells (AD-MSCs), drugs, and vaccines in inhibiting COVID-19 disease. Aging Dis 11(5), 1191–1201 (2020).
  • Wu Z, McGoogan JM. Characteristics of an important lessons from the coronavirus disease 2019 (COVID-19) outbreak in china: summary of a report of 72–314 cases from the chinese center for disease control and prevention. JAMA 323(13), 1239–1242 (2020).
  • Shereen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: emergence, transmission, and characteristics of human coronaviruses. Journal of Advanced Research 24, 91–98 (2020).
  • Zhao Y, Zhao Z, Wang Y, Zhou Y, Ma Y, Zuo W. Single-Cell RNA expression profiling of ACE2, the receptor of SARS-CoV-2. Am. J. Respir. Crit. Care Med. 202(5), 756–759 (2020).
  • Alzahrani FA, Saadeldin IM, Ahmad A et al. The potential use of mesenchymal stem cells and their derived exosomes as immunomodulatory agents for COVID-19 patients. Stem cells international 2020, 8835986 (2020).
  • Zheng G, Huang R, Qiu G et al. Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis. Cell Tissue Res. 374(1), 1–15 (2018).
  • Su N, Gao PL, Wang K, Wang JY, Zhong Y, Luo Y. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: a new dimension in cell-material interaction. Biomaterials 141, 74–85 (2017).
  • Majolo F, da Silva GL, Vieira L, Timmers L, Laufer S, Goettert MI. Review of trials currently testing stem cells for treatment of respiratory diseases: facts known to date and possible applications to COVID-19. Stem Cell Rev Rep 17(1), 44–55 (2021).
  • Samara A, Herlenius E. Is there an effect of fetal mesenchymal stem cells in the mother-fetus dyad in COVID-19 pregnancies and vertical transmission? Front Physiol 11, 624625 (2020).
  • Hadi A, Kadhom M, Hairunisa N, Yousif E, Mohammed S. A review on COVID-19: origin, spread, symptoms, treatment and prevention. Biointerface Research in Applied Chemistry 10, 7234–7242 (2020).
  • Chrzanowski W, Kim SY, McClements L. Can stem cells beat COVID-19: advancing stem cells and extracellular vesicles toward mainstream medicine for lung injuries associated with SARS-CoV-2 infections. Front Bioeng Biotechnol 8, 554 (2020).
  • Friedenstein AJ, Petrakova KV, Kurolesova AI, Frolova GP. Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 6(2), 230–247 (1968).
  • Phinney DG. Building a consensus regarding the nature and origin of mesenchymal stem cells. Journal of cellular biochemistry. Supplement 38, 7–12 (2002).
  • Main H, Munsie M, O'Connor MD. Managing the potential and pitfalls during clinical translation of emerging stem cell therapies. Clin Transl Med 3, 10 (2014).
  • Dominici M, Le Blanc K, Mueller I et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8(4), 315–317 (2006).
  • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 284(5411), 143–147 (1999).
  • Li C, Zhang W, Jiang X, Mao N. Human-placenta-derived mesenchymal stem cells inhibit proliferation and function of allogeneic immune cells. Cell Tissue Res. 330(3), 437–446 (2007).
  • O'Donoghue K, Choolani M, Chan J et al. Identification of fetal mesenchymal stem cells in maternal blood: implications for non-invasive prenatal diagnosis. Mol Hum Reprod 9(8), 497–502 (2003).
  • Li TS, Hayashi M, Ito H et al. Regeneration of infarcted myocardium by intramyocardial implantation of ex vivo transforming growth factor-beta-preprogrammed bone marrow stem cells. Circulation 111(19), 2438–2445 (2005).
  • Tang L, Jiang Y, Zhu M et al. Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19. Front Med 14(5), 664–673 (2020).
  • Matthay MA, Calfee CS, Zhuo H et al. Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase IIa safety trial. Lancet Respir Med 7(2), 154–162 (2019).
  • Chen J, Hu C, Chen L et al. Clinical study of mesenchymal stem cell treatment for acute respiratory distress syndrome induced by epidemic influenza A (H7N9) infection: a hint for COVID-19 treatment. Engineering (Beijing) 6(10), 1153–1161 (2020).
  • Du YM, Zhuansun YX, Chen R, Lin L, Lin Y, Li JG. Mesenchymal stem cell exosomes promote immunosuppression of regulatory T cells in asthma. Exp. Cell Res. 363(1), 114–120 (2018).
  • Li F. Structure, Function, and Evolution of Coronavirus Spike Proteins. Annu Rev Virol 3(1), 237–261 (2016).
  • Manning CN, Martel C, Sakiyama-Elbert SE et al. Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro. Stem Cell Res Ther 6(1), 74 (2015).
  • Leng Z, Zhu R, Hou W et al. Transplantation of ACE2(-) mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia. Aging Dis 11(2), 216–228 (2020).
  • Al Jumah MA, Abumaree MH. The immunomodulatory and neuroprotective effects of mesenchymal stem cells (MSCs) in experimental autoimmune encephalomyelitis (EAE): a model of multiple sclerosis (MS). Int J Mol Sci 13(7), 9298–9331 (2012).
  • Zheng ZH, Li XY, Ding J, Jia JF, Zhu P. Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the responses of type II collagen-reactive T cells in rheumatoid arthritis. Rheumatology (Oxford) 47(1), 22–30 (2008).
  • Gentile P, Sterodimas A. Adipose-derived stromal stem cells (ASCs) as a new regenerative immediate therapy combating coronavirus (COVID-19)-induced pneumonia. Expert Opin Biol Ther 20(7), 711–716 (2020).
  • Xu Z, Shi L, Wang Y et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med 8(4), 420–422 (2020).
  • Khatri M, Richardson LA, Meulia T. Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model. Stem Cell Res Ther 9(1), 17 (2018).
  • Abu-El-Rub E, Khasawneh RR, Almahasneh F et al. Mesenchymal stem cells and COVID-19: what they do and what they can do. World journal of stem cells 13(9), 1318–1337 (2021).
  • Qiancheng X, Jian S, Lingling P et al. Coronavirus disease 2019 in pregnancy. Int J Infect Dis 95, 376–383 (2020).
  • Jamieson DJ, Rasmussen SA. An update on COVID-19 and pregnancy. Am. J. Obstet. Gynecol. 226(2), 177–186 (2022).
  • Naidu SAG, Clemens RA, Pressman P, Zaigham M, Davies KJA, Naidu AS. COVID-19 during pregnancy and postpartum. J. Diet Suppl. 19(1), 78–114 (2022).
  • Kasraeian M, Zare M, Vafaei H et al. COVID-19 pneumonia and pregnancy; a systematic review and meta-analysis. J Matern Fetal Neonatal Med 35(9), 1652–1659 (2022).
  • Easter SR, Gupta S, Brenner SK, Leaf DE. Outcomes of critically Ill pregnant women with COVID-19 in the United States. Am. J. Respir. Crit. Care Med. 203(1), 122–125 (2021).
  • Ellington S, Strid P, Tong VT et al. Characteristics of women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status - United States, January 22–June 7, 2020. MMWR Morb. Mortal. Wkly Rep. 69(25), 769–775 (2020).
  • Shoji K, Tsuzuki S, Akiyama T et al. Clinical characteristics and outcomes of coronavirus disease 2019 (COVID-19) in pregnant women: a propensity score-matched analysis of data from the COVID-19 Registry Japan. Clin. Infect. Dis. 75(1), e397–e402 (2022).
  • Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound Obstet. Gynecol. 56(1), 15–27 (2020).
  • Chen L, Li Q, Zheng D et al. Clinical characteristics of pregnant women with Covid-19 in Wuhan, China. N. Engl. J. Med. 382(25), e100 (2020).
  • Wilkinson M, Johnstone ED, Simcox LE, Myers JE. The impact of COVID-19 on pregnancy outcomes in a diverse cohort in England. Sci Rep 12(1), 942 (2022).
  • Papapanou M, Papaioannou M, Petta A et al. Maternal and neonatal characteristics and outcomes of COVID-19 in pregnancy: an overview of systematic reviews. Int J Environ Res Public Health 18(2), 596 (2021).
  • Zambrano LD, Ellington S, Strid P et al. Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 Infection by pregnancy status - United States, January 22–October 3, 2020. MMWR Morb. Mortal. Wkly Rep. 69(44), 1641–1647 (2020).
  • Badell ML, Dude CM, Rasmussen SA, Jamieson DJ. Covid-19 vaccination in pregnancy. BMJ 378, e069741 (2022).
  • Wastnedge EAN, Reynolds RM, van Boeckel SR et al. Pregnancy and COVID-19. Physiol. Rev. 101(1), 303–318 (2021).
  • Ahlberg M, Neovius M, Saltvedt S et al. Association of SARS-CoV-2 test status and pregnancy outcomes. JAMA 324(17), 1782–1785 (2020).
  • Khoury R, Bernstein PS, Debolt C et al. Characteristics and outcomes of 241 births to women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at five New York City medical centers. Obstet. Gynecol. 136(2), 273–282 (2020).
  • Dashraath P, Wong JLJ, Lim MXK et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am. J. Obstet. Gynecol. 222(6), 521–531 (2020).
  • Zha Y, Chen G, Gong X et al. Coronavirus disease 2019 in pregnant and non-pregnant women: a retrospective study. Chin Med J (Engl) 134(10), 1218–1220 (2021).
  • Khan DSA, Pirzada AN, Ali A, Salam RA, Das JK, Lassi ZS. The differences in clinical presentation, management, and prognosis of laboratory-confirmed COVID-19 between pregnant and non-pregnant women: a systematic review and meta-analysis. Int J Environ Res Public Health 18(11), 5613 (2021).
  • Zheng G, Huang L, Tong H et al. Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study. Respir Res 15(1), 39 (2014).
  • Zhou T, Yuan Z, Weng J et al. Challenges and advances in clinical applications of mesenchymal stromal cells. J Hematol Oncol 14(1), 24 (2021).
  • Chen L, Qu J, Kalyani FS et al. Mesenchymal stem cell-based treatments for COVID-19: status and future perspectives for clinical applications. Cell. Mol. Life Sci. 79(3), 142 (2022).
  • Sanchez-Guijo F, Garcia-Arranz M, Lopez-Parra M et al. Adipose-derived mesenchymal stromal cells for the treatment of patients with severe SARS-CoV-2 pneumonia requiring mechanical ventilation. A proof of concept study. EClinicalMedicine 25, 100454 (2020).
  • Qu W, Wang Z, Hare JM et al. Cell-based therapy to reduce mortality from COVID-19: systematic review and meta-analysis of human studies on acute respiratory distress syndrome. Stem Cells Transl Med 9(9), 1007–1022 (2020).
  • Chouw A, Milanda T, Sartika CR, Kirana MN, Halim D, Faried A. Potency of mesenchymal stem cell and its secretome in treating COVID-19. Regen Eng Transl Med 8(1), 43–54 (2022).