References
- ChanPFHolmesDJPayneDJFinding the gems using genomic discovery: antibacterial drug discovery strategies – the successes and the challengesDrug Discov Today Ther Strateg20041519527
- PayneDJGwynnMNHolmesDJPomplianoDLDrugs for bad bugs: confronting the challenges of antibacterial discoveryNat Rev Drug Discov20076294017159923
- BlackMTBrutonGInhibitors of bacterial signal peptidasesCurr Pharm Des1998413315410197037
- EisenthalRCornish-BowdenAProspects for antiparasitic drugs. The case of Trypanosoma brucei, the causative agent of sleeping sicknessJ Biol Chem1998273550055059488673
- KohanskiMADwyerDJHayeteBLawrenceCACollinsJJA common mechanism of cellular death induced by bactericidal antibioticsCell200713079781017803904
- BarveAGuptaASolapureSMA kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coliAdv Appl Bioinform Chem201039711021918631
- DattaSUnderstanding the characteristics of a good anti-infective drug targetJ Parasitic Dis199923139140
- KaurPAgarwalSDattaSIPTG inducible promoter system for delineating bacteristatic and bactericidal targets in mycobacteriaPloS One20094e592319526063
- PollegioniLSchonbrunnESiehlDMolecular basis of glyphosate resistance-different approaches through protein engineeringFEBS J20112782753276621668647
- BentleyRThe shikimate pathway – a metabolic tree with many branchesCrit Rev Biochem Mol Biol1990253073842279393
- de MaríaNBecerrilJMGarcía-PlazaolaJIHernandezADe FelipeMRFernandez-PascualMNew insights on glyphosate mode of action in nodular metabolism: role of shikimate accumulationJ Agric Food Chem2006542621262816569053
- OliveiraJSPintoCABassoLASantosDSCloning and over-expression in soluble form of fuctional shikimate kinase and 5-enolpyruvylshikimate 3-phosphate synthase enzymes from Mycobacterium tuberculosisProtein Expr Purif20012243043511483005
- OliveiraJSMendesMAPalmaMSBassoLASantosDSOne step purification of 5-enolpyruvylshikimate 3-phosphate synthase enzymes from Mycobacterium tuberculosisProtein Expr Purif20032828729212699693
- BradfordMA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnal Biochem197672248254942051
- WebbMRA continuous spectrophotometric assay for inorganic phosphate and for measuring phosphate release kinetics in biological systemsProc Natl Acad Sci U S A199289488448871534409
- Molecular Probes. EnzChek Phosphate Assay Kit (E-6646) product information. 2002. Available from: http://probes.invitrogen.com/media/pis/mp06646.pdf. Accessed December 2, 2012.
- BowdenSDRamachandranVKKnudsenGMHintonJCThompsonAAn incomplete TCA cycle increases survival of Salmonella typhimurium during infection of resting and activated murine macrophagesPLoS One20105e1387121079785
- SinghAKarimpour-FardAGillRTIncreased mutation frequency in redox-impaired Escherichia coli due to RelA- and RpoS-mediated repression of DNA repairAppl Environ Microbiol2010765463547020581184
- AlibhaiMFStallingsWCClosing down on glyphosate inhibition – with a new structure for drug discoveryProc Natl Acad Sci U S A2001982944294611248008
- HuynhQKKishoreGMBildGS5-enolpyruvylshikimate 3-phosphate synthase enzymes from Escherichia coli, identification of Lys-22 as a potential active site residueJ Biol Chem19882637357393121621
- ShuttleworthWAEvansJNSSite-directed mutagenesis and NMR studies of histidine-385 mutants of 5-enolpyruvylshikimate 3-phosphate synthase enzymesBiochemistry199433706270688003471
- ShuttleworthWAPohlMEHelmsGLJakemanDLEvansJNSite-directed mutagenesis of putative active site residues of 5-enolpyruvylshikimate 3-phosphate synthase enzymesBiochemistry1999382963029890910
- EschenburgSHealyMLPriestmanMALushingtonGHSchönbrunnEHow the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvylshikimate 3-phosphate synthase enzymes from Escherichia coliPlanta200221612913512430021
- SharmaUCurrent possibilities and unresolved issues of drug target validation in Mycobacterium tuberculosisExpert Opin Drug Discov201161171118622646985
- SauroHMEnzyme Kinetics for Systems BiologyLexington (KY)Ambrosius2011
- LarssonESanderCMarksDmRNA turnover rate limits siRNA and microRNA efficacyMol Syst Biol2010643321081925
- LiLLuWHanYA novel RPMXR motif among class II 5-enolpyruvylshikimate-3-phosphate synthases is required for enzymatic activity and glyphosate resistanceJ Biotechnol200914433033619799945
- PengLArauzo-BravoMJShimizuKMetabolic flux analysis for a ppc mutant Escherichia coli based on 13C-labelling experiments together with enzyme activity assays and intracellular metabolite measurementsFEMS Microbiol Lett2004235172315158257
- FongSSNanchenAPalssonBOSauerULatent pathway activation and increased pathway capacity enable Escherichia coli adaptation to loss of key metabolic enzymesJ Biol Chem20062818024803316319065
- SauerUCanonacoFHeriSPerrenoudAFischerEThe soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coliJ Biol Chem200427986613661914660605