References
- OyoshiMKHeRKumarLYoonJGehaRSCellular and molecular mechanisms in atopic dermatitisAdv Immunol200910213522619477321
- BieberTAtopic dermatitisN Engl J Med2008358141483149418385500
- BoguniewiczMLeungDYAtopic dermatitis: a disease of altered skin barrier and immune dysregulationImmunol Rev2011242123324621682749
- RattenhollASteinhoffMProteinase-activated receptor-2 in the skin: receptor expression, activation and function during health and diseaseDrug News Perspect200821736938119259550
- PastoreSMasciaFGirolomoniGThe contribution of keratinocytes to the pathogenesis of atopic dermatitisEur J Dermatol200616212513116581561
- Gutowska-OwsiakDOggGSThe epidermis as an adjuvantJ Invest Dermatol20121323 Pt 294094822217742
- IwasakiAMedzhitovRToll-like receptor control of the adaptive immune responsesNat Immunol200451098799515454922
- ManicassamySPulendranBModulation of adaptive immunity with Toll-like receptorsSemin Immunol200921418519319502082
- HataTRGalloRLAntimicrobial peptides, skin infections, and atopic dermatitisSemin Cutan Med Surg200827214415018620136
- MandronMArièsMFBrehmRDTranterHSAcharyaKRCharveronMDavrincheCHuman dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarizationJ Allergy Clin Immunol200611751141114716675344
- HasannejadHTakahashiRKimishimaMHayakawaKShioharaTSelective impairment of Toll-like receptor 2-mediated proinflammatory cytokine production by monocytes from patients with atopic dermatitisJ Allergy Clin Immunol20071201697517531301
- NiebuhrMLutatCSigelSWerfelTImpaired TLR-2 expression and TLR-2-mediated cytokine secretion in macrophages from patients with atopic dermatitisAllergy200964111580158719392987
- YamanakaKMizutaniHThe role of cytokines/chemokines in the pathogenesis of atopic dermatitisCurr Probl Dermatol201141809221576949
- KogaCKabashimaKShiraishiNKobayashiMTokuraYPossible pathogenic role of Th17 cells for atopic dermatitisJ Invest Dermatol2008128112625263018432274
- KimBELeungDYBoguniewiczMHowellMDLoricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6Clin Immunol2008126333233718166499
- PigattoPThe efficacy of Avène thermal spring water in light to moderate atopic dermatitisAnn Dermatol Venereol200513210 Pt 26S166S1816340929
- GiannettiAThe hydrotherapy centre in Avène-les-bains. A controlled study in atopic dermatitisAnn Dermatol Venereol200513210 Pt 26S126S1516340928
- TaiebCSibaudVMerial-KienyCImpact of Avène hydrotherapy on the quality of life of atopic and psoriatic patientsJ Eur Acad Dermatol Venereol201125Suppl 12429
- CasasCRibetVAlvarez-GeorgesSSibaudVGuerreroDSchmittAMRedoulesDModulation of interleukin-8 and staphylococcal flora by Avène hydrotherapy in patients suffering from chronic inflammatory dermatosesJ Eur Acad Dermatol Venereol201125Suppl 11923
- BourrainMRibetVCalvezALebaronPSchmittAMBalance between beneficial microflora and Staphylococcus aureus colonisation: in vivo evaluation in patients with atopic dermatitis during hydrotherapyEur J Dermatol201323678679424280310
- PortalèsPArièsMFLicuDImmunomodulation induced by Avène spring water on Th1- and Th2-dependent cytokine production in healthy subjects and atopic dermatitis patientsSkin Pharmacol Appl Skin Physiol200114423424211464106
- Merial-KienyCCastex-RizziNSelasBMerySGuerreroDAvène Thermal Spring Water: an active component with specific propertiesJ Eur Acad Dermatol Venereol201125Suppl 125
- BourrainMVilletteCNguyenTLebaronPAquaphilus dolomiae gen. nov., sp. nov., isolated from a deep aquiferVie Milieu201262191195
- Castex-RizziNGallianoMFAriesMFIn vitro approaches to pharmacological screening in the field of atopic dermatitisBr J Dermatol2014170Suppl 1121824930566
- KinoshitaHTakaiTLeTACytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNAJ Allergy Clin Immunol2009123117918619056108
- BernardFXMorelFCamusMKeratinocytes under fire of pro-inflammatory cytokines: bona fide innate immune cells involved in the physiopathology of chronic atopic dermatitis and psoriasisJ Allergy (Cairo)2012201271872523193414
- BaoLShiVYChanLSIL-4 up-regulates epidermal chemotactic, angiogenic, and pro-inflammatory genes and down-regulates antimicrobial genes in vivo and in vitro: relevant in the pathogenesis of atopic dermatitisCytokine201361241942523207180
- MosmannTRapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assaysJ Immunol Methods1983651–255636606682
- BoukampPPetrussevskaRTBreitkreutzDHornungJMarkhamAFusenigNENormal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell lineJ Cell Biol198810637617712450098
- CasasCGinistyHAlvarez-GeorgesSMolecular characterization of inflammation and Staphylococcus aureus colonization of involved skin of atopic dermatitis patients. A non-invasive approachSkin Pharmacol Physiol200821526026818612217
- SoumelisVRechePAKanzlerHHuman epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLPNat Immunol20023767368012055625
- Leyva-CastilloJMHenerPJiangHLiMTSLP produced by keratinocytes promotes allergen sensitization through skin and thereby triggers atopic march in miceJ Invest Dermatol2013133115416322832486
- KonishiHTsutsuiHMurakamiTIL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditionsProc Natl Acad Sci U S A20029917113401134512151598
- NakanishiKYoshimotoTTsutsuiHOkamuraHInterleukin-18 regulates both Th1 and Th2 responsesAnnu Rev Immunol20011942347411244043
- HomeyBSteinhoffMRuzickaTLeungDYCytokines and chemokines orchestrate atopic skin inflammationJ Allergy Clin Immunol2006118117818916815153
- InoueYAiharaMKirinoMInterleukin-18 is elevated in the horny layer in patients with atopic dermatitis and is associated with Staphylococcus aureus colonizationBr J Dermatol2011164356056721087228
- TsutsuiHMizutaniHNakanishiKContribution of interleukin 18 to the development of infection-associated atopic dermatitisCurr Probl Dermatol2011419310321576950
- AmarbayasgalanTTakahashiHDekioIMoritaEInterleukin-8 content in the stratum corneum as an indicator of the severity of inflammation in the lesions of atopic dermatitisInt Arch Allergy Immunol2013160637422948248
- LeeSEJeongSKLeeSHProtease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitisYonsei Med J201051680882220879045
- WilsonSRThéLBatiaLMThe epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itchCell2013155228529524094650
- MoniagaCSJeongSKEgawaGProtease activity enhances production of thymic stromal lymphopoietin and basophil accumulation in flaky tail miceAm J Pathol2013182384185123333753
- NapolitaniGRinaldiABertoniFSallustoFLanzavecchiaASelected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cellsNat Immunol20056876977615995707
- KuoIHCarpenter-MendiniAYoshidaTActivation of epidermal toll-like receptor 2 enhances tight junction function: implications for atopic dermatitis and skin barrier repairJ Invest Dermatol2013133498899823223142
- HayashiFSmithKDOzinskyAThe innate immune response to bacterial flagellin is mediated by Toll-like receptor 5Nature200141068321099110311323673
- NakatsujiTGalloRLAntimicrobial peptides: old molecules with new ideasJ Invest Dermatol20121323 Pt 288789522158560
- SchittekBThe antimicrobial skin barrier in patients with atopic dermatitisCurr Probl Dermatol201141546721576947
- OngPYOhtakeTBrandtCEndogenous antimicrobial peptides and skin infections in atopic dermatitisN Engl J Med2002347151151116012374875
- BiragynARuffiniPALeiferCAToll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2Science200229855951025102912411706
- WolfRHowardOMDongHFChemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15J Immunol200818121499150618606705
- Guttman-YasskyENogralesKEKruegerJGContrasting pathogenesis of atopic dermatitis and psoriasis – part II: immune cell subsets and therapeutic conceptsJ Allergy Clin Immunol201112761420143221419481
- MillsKHDunganLSJonesSAHarrisJThe role of inflammasome-derived IL-1 in driving IL-17 responsesJ Leukoc Biol201393448949723271701
- MartinHLaborel-PréneronEFraysseFNguyenTSchmittAMRedoulèsDDavrincheCAquaphilus dolomiae extract counteracts the effects of cutaneous S. aureus secretome isolated from atopic children on CD4+ T cell activationPharm Biol20161414
- No authors listedSeverity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic DermatitisDermatology1993186123318435513
- BianchiPTheunisJCasasCEffects of a new emollient-based treatment on skin microflora balance and barrier function in children with mild atopic dermatitisPediatr Dermatol20163321657127001317