Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study

Juan Pablo Castanedo-Cazares1 Department of Dermatology

Gabryela Lárraga-Piñones1 Department of Dermatology

Adriana Ehnis-Pérez1 Department of Dermatology

Cornelia Fuentes-Ahumada1 Department of Dermatology

Cuauhtemoc Oros-Ovalle2 Department of Pathology, Hospital Central Dr Ignacio Morones Prieto, Universidad Autónoma de San Luis Potosí, México

Bruce R Smoller3 Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AK, USA

Bertha Torres-Álvarez1 Department of DermatologyCorrespondence[email protected]

show all

Pages 29-36 | Published online: 14 Jan 2013

Cite this article

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

AlexisAFSergayABTaylorSCCommon dermatologic disorders in skin of color: a comparative practice surveyCutis20078038739418189024
PubMed Web of Science ®Google Scholar
PapaCMKligmanAMThe behavior of melanocytes in inflammationJ Invest Dermatol1965454654735847001
PubMed Web of Science ®Google Scholar
MottazJHThorneEGZelicksonASResponse of the epidermal melanocyte to minor traumaArch Dermatol19711046116185002251
PubMed Web of Science ®Google Scholar
TomitaYMaedaKTagamiHMelanocyte-stimulating properties of arachidonic acid metabolites: possible role in postinflammatory pigmentationPigment Cell Res199253573611292020
PubMedGoogle Scholar
LamelSARahvarMMaibachHIPostinflammatory hyperpigmentation secondary to external insult: an overview of the quantitative analysis of pigmentationCutan Ocul Toxicol201232677122667459
PubMed Web of Science ®Google Scholar
Al-AboosiMAbalkhailAKasimOFriction melanosis: a clinical, histologic, and ultrastructural study in Jordanian patientsInt J Dermatol20044326126415090007
PubMed Web of Science ®Google Scholar
CallenderVDSt Surin-LordSDavisECMaclinMPostinflammatory hyperpigmentation: etiologic and therapeutic considerationsAm J Clin Dermatol201112879921348540
PubMed Web of Science ®Google Scholar
JamesAGPopleJEParishWEMooreAEDunbarNHistological evaluation of hyperpigmentation on female Filipino axillary skinInt J Cosmet Sci20062824725318489264
PubMedGoogle Scholar
WeisbergNKGreenbaumSSPigmentary changes after alexandrite laser hair removalDermatol Surg20032941541912656825
PubMed Web of Science ®Google Scholar
MagañaMHerrera-GoepfertRFriction hypermelanosis: other variantsJ Am Acad Dermatol20024745412196763
PubMed Web of Science ®Google Scholar
PincelliCMagniRMotoleseAPigmented contact dermatitis from deodorantContact Derm1993283053068365140
PubMed Web of Science ®Google Scholar
Cook-BoldenFEHamiltonS FAn open-label study of the efficacy and tolerability of microencapsulated hydroquinone 4% and retinol 0.15% with antioxidants for the treatment of hyperpigmentationCutis20088136537118491487
PubMed Web of Science ®Google Scholar
GrimesPEManagment of hyperpigmentation in darker racial ethnic groupsSemin Cutan Med Surg200928778519608057
PubMed Web of Science ®Google Scholar
Bulengo-RansbySMGrififthsCEKimbrough-GreenCKTopical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patientsN Engl J Med1993328143814438479462
PubMed Web of Science ®Google Scholar
JacykAKMpofuPAdapalene gel 0.1% for topical treatment of acne vulgaris in African patientsCutis200168485411845948
PubMedGoogle Scholar
GrimesPCallenderVTazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled studyCutis200677455016475496
PubMed Web of Science ®Google Scholar
LoweNJRizkDGrimesPBillipsMPincusSAzelaic acid 20% cream in the treatment of facial hyperpigmentation in darker-skinned patientsClin Ther1998209459599829446
PubMed Web of Science ®Google Scholar
BurnsRLPrevost-BlankPLLawryMALawryTBFariaDTFivensonD PGlycolic acid peels for post- inflammatory hyperpigmentation in black patients: a comparative studyDermatol Surg1997231711749145958
PubMed Web of Science ®Google Scholar
AhnHHKimIHWhitening effect of salicylic acid peels in Asian patientsDermatol Surg20063237237516640681
PubMed Web of Science ®Google Scholar
PolderKDLandauJMVergilis-KalnerIJGoldbergLHFriedmanPMBruceSLaser eradication of pigmented lesions: a reviewDermatol Surg20113757259521492309
PubMed Web of Science ®Google Scholar
HakozakiTMinwallaLZhuangJThe effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transferBr J Dermatol2002147203112100180
PubMed Web of Science ®Google Scholar
BissettDLMiyamotoKSunPTopical niacinamide produces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skinInt J Cosmet Sci20042623123818492135
PubMedGoogle Scholar
Cosmetic Ingredient Review Expert PanelFinal report of the safety assessment of niacinamide and niacinInt J Toxicol200524 Suppl 5131
Google Scholar
Navarrete-SolísJCastanedo-CázaresJ PTorres-ÁlvarezBA double-blind, randomized clinical trial of niacinamide 4% versus hydroquinone 4% in the treatment of melasmaDermatol Res Pract2011201137917321822427
PubMedGoogle Scholar
TakiwakiHShiraiSKohnoHSohHAraseSThe degrees of UVB-induced erythema and pigmentation correlate linearly and are reduced in a parallel manner by topical anti-inflammatory agentsJ Invest Dermatol19941036426467963648
PubMed Web of Science ®Google Scholar
KahanekNGelbardCHebertADesonide: a review of formulations, efficacy and safetyExpert Opin Investig Drugs20081710971104
PubMed Web of Science ®Google Scholar
Torres-ÁlvarezBMesa-GarzaIGCastanedo-CázaresJ PHistochemical and immunohistochemical study in melasma: evidence of damage in the basal membraneAm J Dermatopathol20113329129521317614
PubMed Web of Science ®Google Scholar
UngerstedtJSBlombackMSoderstromTNicotinamide is a potent inhibitor of proinflammatory cytokinesClin Exp Immunol2003131485212519385
PubMed Web of Science ®Google Scholar
BiedrońRCiszekMTokarczykM1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophagesArch Immunol Ther Exp200856127134
PubMed Web of Science ®Google Scholar
HenggeURRuzickaTSchwartzRACorkMJAdverse effects of topical glucocorticosteroidsJ Am Acad Dermatol20065411516384751
PubMed Web of Science ®Google Scholar
GrimesPEA microsponge formulation of hydroquinone 4% and retinol 0.15% in the treatment of melasma and postinflammatory hyperpigmentationCutis20047436236815663072
PubMed Web of Science ®Google Scholar

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date