90
Views
5
CrossRef citations to date
0
Altmetric
Review

New approach to the understanding of keloid: psychoneuroimmune–endocrine aspects

, , &
Pages 67-73 | Published online: 10 Feb 2015

References

  • JuhanDJob’s Body. Skin as Surface of the BrainBarrytown, NYStation Hill Press, Inc20133541
  • HallJMCruserDPodawiltzAMummertDIJonesHMummertMEPsychological stress and the cutaneous immune response: roles of the HPA axis and the sympathetic nervous system in atopic dermatitis and psoriasisDermatol Res Pract2012201240390822969795
  • SuárezALFeramiscoJDKooJSteinhoffMPsychoneuroimmunology of psychological stress and atopic dermatitis: pathophysiologic and therapeutic updatesActa Derm Venereol201292171522101513
  • MiseryLTouboulSVinçotCStress and seborrheic dermatitisAnn Dermatol Venereol20071341183383718033062
  • ChidaYMaoXDoes psychosocial stress predict symptomatic herpes simplex virus recurrence? A meta-analytic investigation on prospective studiesBrain Behav Immun200923791792519409481
  • ManolacheLBeneaVStress in patients with alopecia areata and vitiligoJ Eur Acad Dermatol Venereol200721792192817659001
  • YuRHuangYZhangXZhouYPotential role of neurogenic inflammatory factors in the pathogenesis of vitiligoJ Cutan Med Surg201216423024422784515
  • YosipovitchGTangMDawnAGStudy of psychological stress, sebum production and acnevulgaris in adolescentsActa Derm Venereol200787213513917340019
  • HadshiewIMFoitzikKArckPCPausRBurden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopeciaJ Invest Dermatol200412345545715304082
  • ArckPPausRFrom the brain-skin connection: the neuroendocrine-immune misalliance of stress and itchNeuroimmunomodulation2006135–634735617709957
  • Lugović-MihićLLjubešićLMihićJVuković-CvetkovićVTroskotNŠitumMPsychoneuroimmunologic aspects of skin diseasesActa Clin Croat20135233734524558766
  • ArckPCSlominskiATheoharidesTCPetersEMPausRNeuroimmunology of stress: skin takes center stageJ Invest Dermatol200612681697170416845409
  • PausRTheoharidesTCArckPCNeuroimmunoendocrine circuitry of the ‘brain-skin connection’Trends Immunol2006271323916269267
  • AderRCohenNFeltenDPsychoneuroimmunology: interactions between the nervous system and the immune systemLancet19953458942991037815892
  • FurtadoFHochmanBFerraraSFWhat factors affect the quality of life of patients with keloids?Rev Assoc Med Bras200955670070420191224
  • RoostermanDGoergeTSchneiderSWBunnettNWSteinhoffMNeuronal control of skin function: the skin as a neuroimmunoendocrine organPhysiol Rev20068641309137917015491
  • BosJDKapsenbergMLThe skin immune system: progress in cutaneous biologyImmunol Today199314275788447935
  • ZouboulisCCHuman skin: an independent peripheral endocrine organHorm Res2000545–623024211595811
  • KonoMNagataHUmemuraSKawanaSOsamuraRYIn situ expression of corticotrophin-releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skinFASEB J200115122297229911511529
  • WakamatsuKGrahamACookDThodyAJCharacterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptorPigment Cell Res19971052882979359624
  • SlominskiAZbytekBNikolakisGSteroidogenesis in the skin: implications for local immune functionsJ Steroid Biochem Mol Biol201313710712323435015
  • LugerTAEpidermal cytokinesActa Derm Venereol Suppl (Stockh)198915161762696309
  • AnselJPerryPBrownJCytokine modulation of keratinocyte cytokinesJ Invest Dermatol199094Suppl 6101S107S2161884
  • BlalockJEThe immune system as the sixth senseJ Inter Med20052572126138
  • FerreiraLMGragnaniAFurtadoFHochmanBControl of the skin scarring responseAn Acad Bras Cienc200981362362919722029
  • SlominskiATZmijewskiMAZbytekBTobinDJTheoharidesTCRivierJKey role of CRF in the skin stress response systemEndocr Rev201334682788423939821
  • JankordRHermanJPLimbic regulation of hypothalamo-pituitary-adrenocortical function during acute and chronic stressAnn N Y Acad Sci20081148647319120092
  • SlominskiAPisarchikATobinDJMazurkiewiczJEWortsmanJDifferential expression of a cutaneous corticotropin-releasing hormone systemEndocrinology2004145294195014605004
  • HsuSYHsuehAJHuman stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptorNat Med20017560561111329063
  • GrammatopoulosDKChrousosGPFunctional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonistsTrends Endocrinol Metab2002131043644412431840
  • SlominskiASzczesniewskiAWortsmanJLiquid chromatography-mass spectrometry detection of corticotropin-releasing hormone and proopiomelanocortin-derived peptides in human skinJ Clin Endocrinol Metab200085103582358811061505
  • TeofoliPMotokiKLottiTMUittoJMauvielAPropiomelanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: modulation by cytokinesExp Dermatol1997631111159226132
  • ItoNItoTKrommingaAHuman hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisolFASEB J200519101332133415946990
  • FoitzikKKrauseKNixonAJProlactin and its receptor are expressed in murine hair follicle epithelium, show hair cycle-dependent expression, and induce catagenAm J Pathol200316251611162112707045
  • LanganEAFoitzik-LauKGoffinVRamotYPausRProlactin: an emerging force along the cutaneous-endocrine axisTrends Endocrinol Metab201021956957720598901
  • RamotYBíróTTiedeSProlactin – a novel neuroendocrine regulator of human keratin expression in situFASEB J20102461768177920103718
  • SlominskiATobinDJZmijewskiMAWortsmanJPausRMelatonin in the skin: synthesis, metabolism and functionsTrends Endocrinol Metab2008191172418155917
  • WeiheESchützBHartschuhWAnlaufMSchäferMKEidenLECoexpression of cholinergic and noradrenergic phenotypes in human and nonhuman autonomic nervous systemJ Comp Neurol2005492337037916217790
  • JoachimRAKuhlmeiADinhQTNeuronal plasticity of the “brain-skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathwaysJ Mol Med (Berl)200785121369137817639286
  • Levi-MontalciniRSkaperSDDal TosoRPetrelliLLeonANerve growth factor: from neurotrophin to neurokineTrends Neurosci199619115145208931279
  • PetersEMBotchkarevVABotchkarevaNVTobinDJPausRHair-cycle-associated remodeling of the peptidergic innervations of murine skin, and hair growth modulation byneuropeptidesJ Invest Dermatol2001116223624511179999
  • UrpeMBuggianiGLottiTStress and psychoneuroimmunologic factors in dermatologyDermatol Clin200523460961716112436
  • HochmanBFurtadoFIsoldiFCNishiokaMAFerreiraLMPsychological stress and skin wound healing: new highlightsCavalcantiLAzevedoSPsychology of StressNew York, NYNova Science Publishers Inc2013148 Available from: https://www.novapublishers.com/catalog/product_info.php?products_id=42015&osCsid=a79df5592f9331df1e8f8cf43e6796c1Accessed September 24, 2014
  • AkaishiSOgawaRHyakusokuHKeloid and hypertrophic scar: neurogenic inflammation hypothesesMed Hypotheses2008711323818406540
  • YagmurCAkaishiSOgawaRGunerenEMechanical receptor-related mechanisms in scar management: a review and hypothesisPlast Reconstr Surg2010126242643420375759
  • OgawaRMechanobiology of scarringWound Repair Regen201119Suppl 1s2s921793962
  • OgawaRHsuCKMechanobiological dysregulation of the epidermis and dermis in skin disorders and in degenerationJ Cell Mol Med201317781782223672502
  • KadanoffDNeurotization and innervation of the human scar-keloidsZ Haut Geschlechtskr196944219259305396789
  • HochmanBNahasFXSobralCSNerve fibres: a possible role in keloid pathogenesisBr J Dermatol2008158365165218205867
  • ParkhouseNCroweRMcGroutherDABurnstockGPainful hypertrophic scarring and neuropeptidesLancet1992340883214101360111
  • CroweRParkhouseNMcGroutherDBurnstockGNeuropeptide-containing nerves in painful hypertrophic human scar tissueBr J Dermatol199413044444527514432
  • ZhangLQLaatoMInnervation of normal and hypertrophic human scars and experimental wounds in the ratAnn Chir Gynaecol200121590293212041924
  • TeyHLMaddisonBWangHCutaneous innervation and itch in keloidsActa Derm Venereol201292552953122378106
  • ZhiboXMiaoboZIntralesional botulinum toxin type A injection as a new treatment measure for keloidsPlast Reconstr Surg20091245275e277e
  • UyesugiBLippincottBDaveSTreatment of a painful keloid with botulinum toxin type AAm J Phys Med Rehabil201089215315519884811
  • RobinsonAJKhadimMFKhanKKeloid scars and treatment with botulinum toxin type A: the Belfast experienceJ Plast Reconstr Aesthet Surg201366343944023092904
  • WilsonAMEradication of keloids: surgical excision followed by a single injection of intralesional 5-fluorouracil andbotulinum toxinCan J Plast Surg2013212879124431948
  • KimLRWhelpdaleKZurowskiMPomeranzBSympathetic denervation impairs epidermal healing in cutaneous woundsWound Repair Regen1998631942019776863
  • ScholzenTEBrzoskaTKaldenDHEffect of ultraviolet light on the release of neuropeptides and neuroendocrine hormones in the skin: mediators of photodermatitis and cutaneous inflammationJ Investig Dermatol Symp Proc1999415560
  • LouwLThe keloid phenomenon: progress toward a solutionClin Anat200720131416944532
  • MeeranSMSinghTNagyTRKatiyarSKHigh-fat diet exacerbates inflammation and cell survival signals in the skin of ultraviolet B-irradiated C57BL/6 miceToxicol Appl Pharmacol2009241330331019747500
  • FerreiraACHochmanBFurtadoFBonattiSFerreiraLMKeloids: a new challenge for nutritionNutr Rev201068740941720591108
  • DhabharFSPsychological stress and immunoprotection versus immunopathology in the skinClin Dermatol2013311183023245970
  • HochmanBVilas BôasFCMarianoMFerreirasLMKeloid heterograft in the hamster (Mesocricetus auratus) cheek pouch, BrazilActa Cir Bras200520320021216033178
  • NirodiCSDevalarajaRNanneyLBChemokine and chemokine receptor expression in keloid and normal fibroblastsWound Repair Regen20008537138211115149
  • WilkeKMartinATerstegenLBielSSA short history of sweat gland biologyInt J Cosmetic Sci2007293169179
  • ZouboulisCCThe sebaceous glandHautarzt201061646746820512305
  • LugerTALottiTNeuropeptides: role in inflammatory skin diseasesJ Eur Acad Dermatol Venereol19981032072119643321
  • HarvimaITNilssonGNaukkarinenARole of mast cells and sensory nerves in skin inflammationG Ital Dermatol Venereol2010145219520420467393
  • HarvimaITNilssonGStress, the neuroendocrine system and mast cells: current understanding of their role in psoriasisExpert Rev Clin Immunol20128323524122390488
  • LeeYSVijayasingamSMast cells and myofibroblasts in keloid: a light microscopic, immunohistochemical and ultrastructural studyAnn Acad Med Singapore19952469029058839007
  • ShakerSAAyuobNNHajrahNHCell talk: a phenomenon observed in the keloid scar by immunohistochemical studyAppl Immunohistochem Mol Morphol201119215315920881838
  • MessadiDVLeABergSHuangGZhuangWBertolamiCNEffect of TGF-beta 1 on PDGF receptors expression in human scar fibroblastsFront Biosci19983a16a229450987
  • FujiwaraMMuragakiYOoshimaAUpregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activityArch Dermatol Res2005297416116916184401
  • CampanerABFerreiraLMGragnaniABruderJMCusickJLMorganJRUpregulation of TGF-beta1 expression may be necessary but is not sufficient for excessive scarringJ Invest Dermatol200612651168117616498396
  • AbdouAGMaraeeAHAl-BaraAMDiabWMImmunohistochemical expression of TGF-β1 in keloids and hypertrophic scarsAm J Dermatopathol2011331849120559120
  • KikuchiKKadonoTTakeharaKEffects of various growth factors and histamine on cultured keloid fibroblastsDermatology19951901487894095
  • McCauleyRLChopraVLiYYHerndonDNRobsonMCAltered cytokine production in black patients with keloidsJ Clin Immunol19921243003081512303
  • GhazizadehMTosaMShimizuHHyakusokuHKawanamiOFunctional implications of the IL-6 signaling pathway in keloid pathogenesisJ Invest Dermatol200712719810517024100
  • GhazizadehMEssential role of IL-6 signaling pathway in keloid pathogenesisJ Nippon Med Sch2007741112217384473
  • UittoJIL-6 signaling pathway in keloids: a target for pharmacologic intervention?J Invest Dermatol200712716817170717
  • EishiKBaeSJOgawaFHamasakiYShimizuKKatayamaISilicone gel sheets relieve pain and pruritus with clinical improvement of keloid: possible target of mast cellsJ Dermatolog Treat200314424825214660274
  • FurtadoFHochmanBFarberPLMullerMCHayashiLFFerreiraLMPsychological stress as a risk factor for postoperative keloid recurrenceJ Psychosom Res201272428228722405222
  • DuraniPBayatALevels of evidence for the treatment of keloid diseaseJ Plast Reconstr Aesthet Surg200861141717644502
  • GauglitzGGManagement of keloids and hypertrophic scars: current and emerging optionsClin Cosmet Investig Dermatol20136103114
  • AlonsoPERiojaLFPeraCKeloids: a viral hypothesisMed Hypotheses20087015616617509771
  • de MesquitaCJAbout strawberry, crab claws, and the Sir James Black’s invention. Hypothesis: can we battle keloids with propranolol?Med Hypotheses20107435335919758768
  • HuangCAkaishiSHyakusokuHOgawaRAre keloid and hypertrophic scar different forms of the same disorder? A fibroproliferative skin disorder hypothesis based on keloid findingsInt Wound J Epub11222012
  • DongXMaoSWenHUpregulation of proinflammatory genes in skin lesions may be the cause of keloid formation [review]Biomed Rep20131683383624649037
  • ShihBBayatAGenetics of keloid scarringArch Dermatol Res2010302531933920130896
  • HalimASEmamiASalahshourifarIKannanTPKeloid scarring: understanding the genetic basis, advances, and prospectsArch Plast Surg201239318418922783524
  • BurdAHuangLHypertrophic response and keloid diathesis: two very different forms of scarPlast Reconstr Surg20051167150e157e
  • NirodiCSDevalarajaRNanneyLBChemokine and chemokine receptor expression in keloid and normal fibroblastsWound Repair Regen20008537138211115149
  • ZhangQYamazaTKellyAPTumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axisPLoS One2009411e779819907660
  • QuMSongNChaiGWuXLiuWPathological niche environment transforms dermal stem cells to keloid stem cells: a hypothesis of keloid formation and developmentMed Hypotheses201381580781224074897