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REVIEW

Privatization and Oligopolies of the Renal Replacement Therapy Sector on Contemporary Capitalism: A Systematic Review and the Brazilian Scenario

ORCID Icon, & ORCID Icon
Pages 417-435 | Received 28 Feb 2024, Accepted 03 May 2024, Published online: 14 May 2024

References

  • Luyckx VA, Tonelli M, Stanifer JW. The global burden of kidney disease and the sustainable development goals. Bull World Health Organ. 2018;96(6):414–422D. doi:10.2471/BLT.17.206441
  • Liyanage T, Ninomiya T, Jha V, et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 2015;385(9981):1975–1982. doi:10.1016/S0140-6736(14)61601-9
  • Stevens PE, Levin A; Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med. 2013;158(11):825–830. doi:10.7326/0003-4819-158-11-201306040-00007
  • Tonelli M, Wiebe N, Knoll G, et al. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant. 2011;11(10):2093–2109. doi:10.1111/j.1600-6143.2011.03686.x
  • Thurlow JS, Joshi M, Yan G, et al. Global epidemiology of end-stage kidney disease and disparities in kidney replacement therapy. Am J Nephrol. 2021;52(2):98–107. doi:10.1159/000514550
  • Sloan CE, Hoffman A, Maciejewski ML, Coffman CJ, Trogdon JG, Wang V. Trends in dialysis industry consolidation after medicare payment reform, 2006–2016. JAMA Health Forum. 2021;2(11):e213626. doi:10.1001/jamahealthforum.2021.3626
  • Silva Junior GBD, Oliveira JGR, Oliveira MRB, Vieira LJES, Dias ER. Global costs attributed to chronic kidney disease: a systematic review. Rev Assoc Med Bras. 2018;64(12):1108–1116. doi:10.1590/1806-9282.64.12.1108
  • Elshahat S, Cockwell P, Maxwell AP, Griffin M, O’Brien T, O’Neill C. The impact of chronic kidney disease on developed countries from a health economics perspective: a systematic scoping review. PLoS One. 2020;15(3):e0230512. doi:10.1371/journal.pone.0230512
  • Yeung E, Bello AK, Levin A, et al. Current status of health systems financing and oversight for end-stage kidney disease care: a cross-sectional global survey. BMJ Open. 2021;11(7):e047245. doi:10.1136/bmjopen-2020-047245
  • Alcalde PR, Kirsztajn GM. Expenses of the Brazilian Public Healthcare System with chronic kidney disease. J Bras Nefrol. 2018;40(2):122–129. doi:10.1590/2175-8239-JBN-3918
  • Brazil, Ministry of Health. National Registry of Health Establishments (Cadastro Nacional de Estabelecimentos de Saúde [CNES]). Available from: http://tabnet.datasus.gov.br/cgi/deftohtm.exe?cnes/cnv/servc2br.def. Accessed April 15, 2023.
  • Brazil, Ministry of Health. Ordinance number 1112, June, 13, 2002. Determines that the group’s procedures - renal replacement therapy - TRS are financed by the strategic actions and compensation fund - FAEC/Strategic actions. Available from: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2002/prt1112_13_06_2002.html. Accessed June 30, 2023.
  • Fulton BD. Health care market concentration trends in the United States: evidence and policy responses. Health Aff. 2017;36(9):1530–1538. doi:10.1377/hlthaff.2017.0556
  • Pescuma-Junior A, Alves DFA, Mendes A, Bousquat A. International capital companies and the Brazilian health system: a study on renal replacement therapy. Cien Saude Colet. 2021;26(9):4163–4172. doi:10.1590/1413-81232021269.20742020
  • Tsai TC, Jha AK. Hospital consolidation, competition, and quality: is bigger necessarily better? JAMA. 2014;312(1):29–30. doi:10.1001/jama.2014.4692
  • Saeed MK, Ho V, Erickson KF. Consolidation in dialysis Markets-Causes, consequences, and the role of policy. Semin Dial. 2020;33(1):90–99. doi:10.1111/sdi.12855
  • Levin DI, Lingam T, Janiga NJ. 2020 outlook: dialysis clinics and ESRD. Available from: https://healthcareappraisers.com/wp-content/uploads/2020/03/FMVantagePoint_2020-OUTLOOK-DIALYSIS-CLINICS-AND-ESRD.pdf. Accessed April 15, 2023.
  • Adler JT, Xiang L, Weissman JS, et al. Association of public reporting of medicare dialysis facility quality ratings with access to kidney transplantation. JAMA Network Open. 2021;4(9):e2126719. doi:10.1001/jamanetworkopen.2021.26719
  • Eliason PJ, Heebsh B, McDevitt RC, Roberts JW. How acquisitions affect firm behavior and performance: evidence from the dialysis industry. Q J Econ. 2020;135(1):221–267. doi:10.1093/qje/qjz034
  • Erickson KF, Zhao B, Niu J, et al. Association of hospitalization and mortality among patients initiating dialysis with hemodialysis facility ownership and acquisitions. JAMA Network Open. 2019;2(5):e193987. doi:10.1001/jamanetworkopen.2019.3987
  • Whittemore R, Knafl K. The integrative review: updated methodology. J Adv Nurs. 2005;52(5):546–553. doi:10.1111/j.1365-2648.2005.03621.x
  • Pan American Health Organization, World Health Organization. Health sciences descriptors. Available from: https://decs.bvsalud.org/. Accessed November 20, 2022.
  • Petticrew M, Shekelle P, Stewart LA, Group P. Preferred reporting items for systematic review and explanation. BMJ. 2015;7647:1–25. doi:10.1136/bmj.g7647
  • Amaral S, McCulloch CE, Lin F, et al. Association between dialysis facility ownership and access to the waiting list and transplant in pediatric patients with end-stage kidney disease in the US. JAMA. 2022;328(5):451–459. doi:10.1001/jama.2022.11231
  • Liu SY, Cheng CY, Wu MY, et al. Effect of profit status in facilities on the mortality of patients on long-term haemodialysis: a nationwide cohort study. BMJ Open. 2021;11(9):e045832. doi:10.1136/bmjopen-2020-045832
  • Dickman S, Mirza R, Kandi M, et al. Mortality at for-profit versus not-for-profit hemodialysis centers: a systematic review and meta-analysis. Int J Health Serv. 2021;51(3):371–378. doi:10.1177/0020731420980682
  • Gander JC, Zhang X, Ross K, et al. Association between dialysis facility ownership and access to kidney transplantation. JAMA. 2019;322(10):957–973. doi:10.1001/jama.2019.12803
  • Erickson KF, Zheng Y, Winkelmayer WC, Ho V, Bhattacharya J, Chertow GM. Consolidation in the dialysis industry, patient choice, and local market competition. Clin J Am Soc Nephrol. 2017;12(3):536–545. doi:10.2215/CJN.06340616
  • Wilson NE. For-profit status and industry evolution in health care markets: evidence from the dialysis industry. Int J Health Econ Manag. 2016;16(4):297–319. doi:10.1007/s10754-016-9192-6
  • Ştefan G, Podgoreanu E, Mircescu G. Hemodialysis system privatization and patient survival: a report from a large registry Eastern Europe cohort. Ren Fail. 2015;37(9):1481–1485. doi:10.3109/0886022X.2015.1077320
  • Brunelli SM, Wilson S, Krishnan M, Nissenson AR. Confounders of mortality and hospitalization rate calculations for profit and nonprofit dialysis facilities: analytic augmentation. BMC Nephrol. 2014;15:121. doi:10.1186/1471-2369-15-121
  • Zhang Y, Thamer M, Kshirsagar O, Cotter DJ, Schlesinger MJ. Dialysis chains and placement on the waiting list for a cadaveric kidney transplant. Transplantation. 2014;98(5):543–551. doi:10.1097/TP.0000000000000106
  • Dalrymple LS, Johansen KL, Romano PS, et al. Comparison of hospitalization rates among for-profit and nonprofit dialysis facilities. Clin J Am Soc Nephrol. 2014;9(1):73–81. doi:10.2215/CJN.04200413
  • Ishida JH, McCulloch CE, Dudley RA, Grimes BA, Johansen KL. Dialysis facility profit status and compliance with a black box warning. JAMA Intern Med. 2013;173(12):1152–1153. doi:10.1001/jamainternmed.2013.979
  • Zhang Y, Thamer M, Kshirsagar O, Cotter DJ. Organizational status of dialysis facilities and patient outcome: does higher injectable medication use mediate increased mortality? Health Serv Res. 2013;48(3):949–971. doi:10.1111/1475-6773.12019
  • Balhara KS, Kucirka LM, Jaar BG, Segev DL. Disparities in provision of transplant education by profit status of the dialysis center. Am J Transplant. 2012;12(11):3104–3110. doi:10.1111/j.1600-6143.2012.04207.x
  • Hynes DM, Stroupe KT, Fischer MJ, et al. Comparing VA and private sector healthcare costs for end-stage renal disease. Med Care. 2012;50(2):161–170. doi:10.1097/MLR.0b013e31822dcf15
  • Zhang Y, Cotter DJ, Thamer M. The effect of dialysis chains on mortality among patients receiving hemodialysis. Health Serv Res. 2011;46(3):747–767. doi:10.1111/j.1475-6773.2010.01219.x
  • Hirth RA, Turenne MN, Wheeler JR, Ma Y, Messana JM. Do resource utilization and clinical measures still vary across dialysis chains after controlling for the local practices of facilities and physicians? Med Care. 2010;48(8):726–732. doi:10.1097/MLR.0b013e3181e3570a
  • Lee DK, Chertow GM, Zenios SA. Reexploring differences among for-profit and nonprofit dialysis providers. Health Serv Res. 2010;45(3):633–646. doi:10.1111/j.1475-6773.2010.01103.x
  • Pozniak AS, Hirth RA, Banaszak-Holl J, Wheeler JR. Predictors of chain acquisition among independent dialysis facilities. Health Serv Res. 2010;45(2):476–496. doi:10.1111/j.1475-6773.2010.01081.x
  • Van Wyck D, Robertson J, Nissenson A, Provenzano R, Kogod D. Relationship among length of facility ownership, clinical performance, and mortality. Clin J Am Soc Nephrol. 2010;5(2):248–251. doi:10.2215/CJN.03700609
  • Mehrotra R, Khawar O, Duong U, et al. Ownership patterns of dialysis units and peritoneal dialysis in the United States: utilization and outcomes. Am J Kidney Dis. 2009;54(2):289–298. doi:10.1053/j.ajkd.2009.01.262
  • Foley RN, Fan Q, Liu J, et al. Comparative mortality of hemodialysis patients at for-profit and not-for-profit dialysis facilities in the United States, 1998 to 2003: a retrospective analysis. BMC Nephrol. 2008;9:6. doi:10.1186/1471-2369-9-6
  • Thamer M, Zhang Y, Kaufman J, Cotter D, Dong F, Hernán MA. Dialysis facility ownership and epoetin dosing in patients receiving hemodialysis. JAMA. 2007;297(15):1667–1674. doi:10.1001/jama.297.15.1667
  • Gitto L, Santoro D, Sobbrio G. Choice of dialysis treatment and type of medical unit (private vs public): application of a recursive bivariate probit. Health Econ. 2006;15(11):1251–1256. doi:10.1002/hec.1139
  • Thamer M, Zhang Y, Kaufman J, Stefanik K, Cotter DJ. Factors influencing route of administration for epoetin treatment among hemodialysis patients in the United States. Am J Kidney Dis. 2006;48(1):77–87. doi:10.1053/j.ajkd.2006.03.040
  • Szczech LA, Klassen PS, Chua B, et al. Associations between CMS’s Clinical Performance Measures project benchmarks, profit structure, and mortality in dialysis units. Kidney Int. 2006;69(11):2094–2100. doi:10.1038/sj.ki.5000267
  • Devereaux PJ, Schünemann HJ, Ravindran N, et al. Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis. JAMA. 2002;288(19):2449–2457. doi:10.1001/jama.288.19.2449
  • Ozgen H, Ozcan YA. A national study of efficiency for dialysis centers: an examination of market competition and facility characteristics for production of multiple dialysis outputs. Health Serv Res. 2002;37(3):711–732. doi:10.1111/1475-6773.00045
  • Irvin RA. Quality of care differences by ownership in United States renal dialysis facilities. ASAIO J. 2000;46(6):775–778. doi:10.1097/00002480-200011000-00023
  • Garg PP, Frick KD, Diener-West M, Powe NR. Effect of the ownership of dialysis facilities on patients’ survival and referral for transplantation. N Engl J Med. 1999;341(22):1653–1660. doi:10.1056/NEJM199911253412205
  • Furth SL, Hwang W, Neu AM, Fivush BA, Powe NR. For-profit versus not-for-profit dialysis care for children with end stage renal disease. Pediatrics. 1999;104(3 Pt 1):519–524. doi:10.1542/peds.104.3.519
  • Griffiths RI, Powe NR, Gaskin DJ, Anderson GF, de Lissovoy GV, Whelton PK. The production of dialysis by for-profit versus not-for-profit freestanding renal dialysis facilities. Health Serv Res. 1994;29(4):473–487.
  • de Lissovoy G, Powe NR, Griffiths RI, et al. The relationship of provider organizational status and erythropoietin dosing in end stage renal disease patients. Med Care. 1994;32(2):130–140. doi:10.1097/00005650-199402000-00004
  • Salman B, Hussain M, Shafique K, Imtiaz S, Dhrolia MF. Risk factors of hospitalization among chronic kidney disease patients in tertiary care hospitals - A single-center experience. Saudi J Kidney Dis Transpl. 2018;29(5):1150–1158. doi:10.4103/1319-2442.243973
  • Mathew AT, Rosen L, Pekmezaris R, et al. Potentially avoidable readmissions in United States hemodialysis patients. Kidney Int Rep. 2017;3(2):343–355. doi:10.1016/j.ekir.2017.10.014
  • Bao C, Bardhan I. Antecedents of patient health outcomes in dialysis clinics: a national study. J Cent Cathedra. 2017;10(1):25–48. doi:10.1108/JCC-09-2016-0015
  • Kimmel PL, Varela MP, Peterson RA, et al. Interdialytic weight gain and survival in hemodialysis patients: effects of duration of ESRD and diabetes mellitus. Kidney Int. 2000;57(3):1141–1151. doi:10.1046/j.1523-1755.2000.00941.x
  • Held PJ, Levin NW, Bovbjerg RR, Pauly MV, Diamond LH. Mortality and duration of hemodialysis treatment. JAMA. 1991;265:871–875.
  • Goldman DP, Vaiana M, Romley JA. The emerging importance of patient amenities in hospital care. N Engl J Med. 2010;363(23):2185–2187. doi:10.1056/NEJMp1009501
  • Hirth RA, Chernew ME, Orzol SM. Ownership, competition, and the adoption of new technologies and cost-saving practices in a fixed-price environment. Inquiry. 2000;37(3):282–294.
  • Lin W-H, Lin C-T, Chang H-F, et al. Financial performance of non-profit hospitals in Taiwan. J Inf Optim Sci. 2011;32:419–431.
  • Brazil, Ministry of Health. National data from the Unified Health System (DATASUS). Health Information. Outpatient and hospital production. Available from: https://datasus.saude.gov.br/informacoes-de-saude-tabnet/. Accessed May 20, 2023.
  • Neves PDMM, Sesso RCC, Thomé FS, Lugon JR, Nasicmento MM. Brazilian Dialysis Census: analysis of data from the 2009-2018 decade. Braz J Bras Nefrol. 2020;42(2):191–200. doi:10.1590/2175-8239-JBN-2019-0234
  • Fontenelle LF, Camargo MBJ, Bertoldi AD, Gonçalves H, Maciel ELN, Barros AJD. Coverage by health insurance or discount cards: a household survey in the coverage area of the Family Health Strategy. Cad Saude Publica. 2017;33(10):e00141515. doi:10.1590/0102-311X00141515
  • Novais M, Martins CB. Profile of Plan and SUS Beneficiaries and Access to Health Services – PNAD 2003 and 2008. Brasil: Instituo de Estudos da Saúde Suplementar; 2010. Available from: www.iess.org.br/sites/default/files/2021-04/TD35.pdf. Accessed December 20, 2023.
  • Nelson KM, Chapko MK, Reiber G, Boyko EJ. The association between health insurance coverage and diabetes care; data from the 2000 Behavioral Risk Factor Surveillance System. Health Serv Res. 2005;40(2):361–372. doi:10.1111/j.1475-6773.2005.00361.x
  • Freeman HE, Corey CR. Insurance status and access to health services among poor persons. Health Serv Res. 1993;28(5):531–541.
  • Barra ABL, Silva APRD, Canziani MEF, Lugon JR, Matos JPS. Survival in hemodialysis in Brazil according to the source of payment for the treatment: Public Healthcare System (SUS) versus private insurance. J Bras Nefrol. 2023;45(3):302–309. doi:10.1590/2175-8239-JBN-2022-0131en
  • da Rocha EP, Kojima CA, Modelli de Andrade LG, et al. Comparing survival outcomes between hemodialysis and hemodiafiltration using real-world data from Brazil. J Clin Med. 2024;13(2):594. doi:10.3390/jcm13020594
  • Mohottige D, Gibson K. Staying on track to achieve racial justice in kidney care. Nat Rev Nephrol. 2022;18(2):72–73. doi:10.1038/s41581-021-00520-5
  • Kevin Tucker J. Social Justice as a Tool to Eliminate Inequities in Kidney Disease. Semin Nephrol. 2021;41(3):203–210. doi:10.1016/j.semnephrol.2021.05.001
  • Farah SS, Alhaji MM, Ahmed D, et al. Barriers to Kidney Transplantation as a Choice of Renal Replacement Therapy. Transplant Proc. 2018;50(10):3165–3171. doi:10.1016/j.transproceed.2018.07.005
  • Zee J, Zhao J, Subramanian L, et al. Perceptions about the dialysis modality decision process among peritoneal dialysis and in-center hemodialysis patients. BMC Nephrol. 2018;19(1):298. doi:10.1186/s12882-018-1096-x
  • Glickman A, Lin E, Berns JS. Conflicts of interest in dialysis: a barrier to policy reforms. Semin Dial. 2020;33(1):83–89. doi:10.1111/sdi.12848
  • Streja E, Park J, Chan TY, et al. Erythropoietin dose and mortality in hemodialysis patients: marginal structural model to examine causality. Int J Nephrol. 2016;2016:6087134. doi:10.1155/2016/6087134
  • Thamer M, Zhang Y, Kaufman J, Kshirsagar O, Cotter D, Hernán MA. Major declines in epoetin dosing after prospective payment system based on dialysis facility organizational status. Am J Nephrol. 2014;40(6):554–560. doi:10.1159/000370334
  • Hirth RA Y, Turenne MN, Wheeler JR, et al. The initial impact of Medicare’s new prospective payment system for kidney dialysis. Am J Kidney Dis. 2013;62(4):662–669. doi:10.1053/j.ajkd.2013.03.044
  • Okpechi IG, Jha V, Cho Y, et al. The case for increased peritoneal dialysis utilization in low- and lower-middle-income countries. Nephrology. 2022;27(5):391–403. doi:10.1111/nep.14024
  • van de Luijtgaarden MW, Jager KJ, Stel VS, et al. Global differences in dialysis modality mix: the role of patient characteristics, macroeconomics and renal service indicators. Nephrol Dial Transplant. 2013;28(5):1264–1275.
  • Mercado-Martinez FJ, Silva DGV, Souza SS, Zillmer JGV, Lopes SGR, Böell JE. Living with renal insufficiency: obstacles to hemodialysis treatment from the perspective of sick people and their families. Physis. 2015;25(1). doi:10.1590/S0103-73312015000100005
  • Pancras G, Shayo J, Anaeli A. Non-medical facilitators and barriers towards accessing haemodialysis services: an exploration of ethical challenges. BMC Nephrol. 2018;19(1):342. doi:10.1186/s12882-018-1140-x
  • Mercado-Martínez FJ, Correa-Mauricio ME. Viviendo con hemodiálisis y sin seguridad social: las voces de los enfermos renales y sus familias [Living in hemodialysis without social insurance: the voices of renal sick people and their families]. Salud Publica Mex. 2015;57(2):155–160. Spanish.
  • McDonald SP, Ullah S, Dansie K, et al. The burden of travel-time and distance traveled for hemodialysis patients in Australian Major City Areas. Kidney Int Rep. 2023;8(5):1105–1108. doi:10.1016/j.ekir.2023.02.1077
  • Msy N, Charu V, Johnson DW, O’Shaughnessy MM, Mallett AJ. National and international kidney failure registries: characteristics, commonalities, and contrasts. Kidney Int. 2022;101(1):23–35. doi:10.1016/j.kint.2021.09.024
  • United States Renal Data System. USRDS Annual Data Report: epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. Available from: https://www.niddk.nih.gov/about-niddk/strategic-plans-reports/usrds. Accessed June 30, 2023.
  • Almasri J, Alsawas M, Mainou M, et al. Outcomes of vascular access for hemodialysis: a systematic review and meta-analysis. J Vasc Surg. 2016;64(1):236–243. doi:10.1016/j.jvs.2016.01.053
  • Franco RP, Chula DC, de Moraes TP, Campos RP. Health insurance provider and endovascular treatment availability are associated with different hemodialysis vascular access profiles: a Brazilian national survey. Front Nephrol. 2022;2:985449. doi:10.3389/fneph.2022.985449
  • Brazil, Ministry of Health. Ordinance number 1675, June 7, 2018. Criteria for the organization, operation and financing of care for people with Chronic Kidney Disease in the Unified Health System. Available from: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2018/prt1675_08_06_2018.html. Accessed May 24, 2023.
  • Thomé FS, Sesso R, Lopes AA, Lugon JR, Martins CT. Brazilian chronic dialysis survey 2017. J Bras Nefrol. 2019;41(2):208–214. doi:10.1590/2175-8239-JBN-2018-0178
  • Emrani Z, Amiresmaili M, Daroudi R, Najafi MT, Akbari Sari A. Payment systems for dialysis and their effects: a scoping review. BMC Health Serv Res. 2023;23(1):45. doi:10.1186/s12913-022-08974-4
  • Santos NRD. 30 years of SUS: the beginning, the pathway and the target. Cien Saude Colet. 2018;23(6):1729–1736. doi:10.1590/1413-81232018236.06092018
  • Noronha JC, Noronha GS, Pereira TR, Costa AM. The future of the Brazilian Health System: a short review of its pathways towards an uncertain and discouraging horizon. Cien Saude Colet. 2018;23(6):2051–2059. doi:10.1590/1413-81232018236.05732018
  • Vieira SF. Health financing in Brazil and the goals of the 2030 Agenda: high risk of failure. Rev Saude Publica. 2020;54:127. doi:10.11606/s1518-8787.2020054002414