158
Views
37
CrossRef citations to date
0
Altmetric
Original Research

Operationalizing a frailty index using routine blood and urine tests

, , , &
Pages 1029-1040 | Published online: 28 Jun 2017

References

  • CrimminsEMLifespan and healthspan: past, present, and promiseGerontologist20155590191126561272
  • JaggerCMatthewsFWohlandPA comparison of health expectancies over two decades in England: results of the Cognitive Function and Ageing Study I and IILancet201638777978626680218
  • ChristnerSRittMVolkertDWirthRSieberCCGaßmannKGEvaluation of the nutritional status of older hospitalised geriatric patients: a comparative analysis of a Mini Nutritional Assessment (MNA) version and the Nutritional Risk Screening (NRS 2002)J Hum Nutr Diet20162970471327298113
  • EschbachDKirchbichlerTWiesmannTNutritional intervention in cognitively impaired geriatric trauma patents: a feasibility studyClin Interv Aging2016111239124627672318
  • KemmlerWTeschlerMGoisserSPrevalence of sarcopenia in Germany and the corresponding effect of osteoarthritis in females 70 years and older living in the community: results of the FORMoSA studyClin Interv Aging2015101565157326491272
  • RittMSchüleinSLubrichHBollheimerLCSieberCCGaßmannKGHigh-technology based gait assessment in frail people: association between spatio-temporal and three-dimensional gait characteristics with frailty status across four different frailty measuresJ Nutr Health Aging20172134635328244577
  • RockwoodKSongXMacKnightCA global clinical measure of fitness and frailty in elderly peopleCMAJ20055489495
  • RockwoodKMitnitskiAHow might deficit accumulation give rise to frailty?J Frailty Aging2012181227092931
  • RockwoodKMitnitskiAFrailty defined by deficit accumulation and geriatric medicine defined by frailtyClin Geriatr Med201127172621093719
  • FriedLPTangenCMWalstonJFrailty in older adults: evidence for a phenotypeJ Gerontol A Biol Sci Med Sci200156M146M15611253156
  • MitnitskiAMogilnerAJRockwoodKAccumulation of deficits as a proxy measure of ageingScientificWorldJournal2001132333612806071
  • RittMBollheimerLCSieberCCGaßmannKGPrediction of one-year mortality by five different frailty instruments: a comparative study in hospitalized geriatric patientsArch Gerontol Geriatr201666667227259029
  • LiuzZWangQZhiTFrailty index and its relation to falls and overnight hospitalizations in elderly Chinese people: a population-based studyJ Nutr Health Aging20162056156827102796
  • Romero-OrtunoRWallisSJBiramRWKeevilVClinical frailty adds to acute illness severity in predicting mortality in hospitalized older adults: an observational studyEur J Intern Med201635243427596721
  • KaehrEWPapeLCMalmstromTKMorleyJEFRAIL-NH predicts outcomes in long term careJ Nutr Health Aging20162019219826812516
  • HubbardREPeelNMSamantaMDerivation of a frailty index from the interRAI acute care instrumentBMC Geriatr2015152725887105
  • MorleyJEVellasBvan KanGAFrailty consensus: a call to actionJ Am Med Dir Assoc20131439239723764209
  • KelaiditiECesariMCanevelliMCognitive frailty: rational and definition from an (I.A.N.A./I.A.G.G.) international consensus groupJ Nutr Health Aging20131772673424154642
  • VellasBCestacPMorleyJEImplementing frailty into clinical practice: we cannot waitJ Nutr Health Aging20121659960022836699
  • McMillanGJHubbardREFrailty in older inpatients: what physicians need to knowQ J Med201210510591065
  • CesariMMarzettiEThiemUThe geriatric management of frailty as paradigm of “The end of the disease era”Eur J Intern Med201631111426997416
  • Romero-OrtunoRO’SheaDFitness and frailty: opposite ends of a challenging continuum! Will the end of age discrimination make frailty assessments an imperative?Age Ageing20134227928023348509
  • MuscedereJAndrewMKBagshawSMScreening for frailty in Canada’s health care system: a time for actionCan J Aging20163528129727211065
  • MitnitskiAGrahamABMogilnerAJRockwoodKFrailty, fitness and late-life mortality in relation to chronological and biological ageBMC Geriatr20022111897015
  • BouillonKKivimakiMHamerMMeasures of frailty in population-based studies: an overviewBMC Geriatr2013136423786540
  • Abellan van KanGRollandYBergmanHMorleyJEKritchevskySBVellasBThe I.A.N.A. Task Force on frailty assessment of older people in clinical practiceJ Nutr Health Aging200812293718165842
  • BieniekJWilcznskiKSzewieczekJFried frailty phenotype assessment components as applied to geriatric inpatientsClin Interv Aging20161145345927217729
  • LisiakMUchmanowiczIWontorRFrailty and quality of life in elderly patients with acute coronary syndromeClin Interv Aging20161155356227217737
  • VerlooHGouletCMorinDvon GuntenAAssociation between frailty and delirium in older adult patients discharged from hospitalClin Interv Aging201611556326848261
  • RittMSchwarzCKronawitterVAnalysis of Rockwood et al’s Clinical Frailty Scale and Fried et al’s frailty phenotype as predictors of mortality and other clinical outcomes in older patients who were admitted to a geriatric wardJ Nutr Health Aging2015191043104826624218
  • RockwoodKTheouOMitnitskiAWhat are frailty instruments for?Age Ageing20154454554725824236
  • HowlettSERockwoodMRMitnitskiARockwoodKStandard laboratory tests to identify older adults at increased risk of deathBMC Med20141217125288274
  • RockwoodKSilviusJLFoxRAComprehensive geriatric assessment: helping your elderly patients maintain functional well-beingPostgrad Med1998103247264
  • RockwoodKRockwoodMRMitnitskiAPhysiological redundancy in older adults in relation to the change with age in the slope of a frailty indexJ Am Geriatr Soc20105831832320370858
  • RittMRadiKHSchwarzCBollheimerLCSieberCCGaßmannKGA comparison of frailty indexes based on a comprehensive geriatric assessment for the prediction of adverse outcomesJ Nutr Health Aging20162076076727499310
  • RockwoodKAndrewMMitnitskiAA comparison of two approaches to measuring frailty in elderly peopleJ Gerontol A Biol Sci Med Sci20076273874317634321
  • RittMRittJISieberCCGaßmannKGComparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wardsClin Interv Aging20171229330428223787
  • RockwoodKMcMillanMMitnitskiAHowlettSEA frailty index based on common laboratory tests in comparison with a clinical frailty index for older adults in long-term care facilitiesJ Am Med Dir Assoc20151684284725952475
  • BlodgettJMTheouOHowlettSEWuFCRockwoodKA frailty index based on laboratory deficits in community-dwelling men predict their risk of adverse health outcomesAge Ageing20164546346827076524
  • MitnitskiACollertonJMartin-RuizCAge-related frailty and its association with biological markers of ageingBMC Med20151316126166298
  • RockwoodKStadnykKMacKnightCMcDowellIHebertRHoganDBA brief clinical instrument to classify frailty in elderly peopleLancet19993532052069923878
  • HinkleDEWiersmaWJursSGApplied Statistics for the Behavioral Sciences5th edBostonHoughton Mifflin2003
  • SwetsJAMeasuring the accuracy of diagnostic systemsScience1988240128512933287615
  • HanleyJAMcNeilBJA method of comparing the areas under receiver operating characteristic curves derived from the same casesRadiology19831488398436878708
  • ChenCSiaIMaHMThe synergistic effect of functional status and comorbidity burden on mortality: a 16-year survival analysisPLoS One20149e10624825170612
  • MarengoniAvon StraussERizzutoDWinbladBFratiglioniLThe impact of chronic multimorbidity and disability on functional decline and survival in elderly persons: a community-based, longitudinal studyJ Intern Med200926528829519192038
  • LandiFLiperotiRRussoADisability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and olderJ Clin Epidemiol20106375275920056387
  • ZekryDValleBHGrafCProspective comparison of 6 comorbidity indices as predictors of 1-year post-hospital discharge institutionalization, readmission, and mortality in elderly individualsJ Am Med Dir Assoc20121327227821450226
  • BelooseskyYWeissAMansurNValidity of the Medication-based Disease Burden Index compared with the Charlson Comorbidity Index and the Cumulative Illness Rating Scale for Geriatrics: a cohort studyDrugs Aging2011281007101422117098
  • KobayashiLCJacksonSELeeSEWardleJSteptoeAThe development and validation of an index to predict 10-year mortality risk in longitudinal cohort of older English adultsAge Ageing Epub2016113
  • MelgaardLGorst-RasmussenARasmussenLHLipGYLarsenRBVascular disease and risk stratification for ischemic stroke and all-cause death in heart failure patients without diagnosed atrial fibrillation: a nationwide cohort studyPlos One201611e015226927015524
  • MandelliSRivaETettamantiMDetomaPGiacominALuccaUMortality prediction in the oldest old with five different equations to estimate glomerular filtration rate: the health and anemia population-based studyPlos One201510e013603926317988
  • Holroyd-LeducJMMehtaKMCovinskyKEUrinary incontinence and its association with death, nursing home admission, and functional declineJ Am Geriatr Soc20045271271815086650
  • BootsmaAMBuurmanBMGeerlingsSEde RooijSEUrinary incontinence and indwelling urinary catheters in acutely admitted elderly patients: relationship with mortality, institutionalization, and functional declineJ Am Med Dir Assoc201314147.e7147.e12
  • KoloskiNAJonesMWaiRGillRSBylesJTalleyNJImpact of persistent constipation on health-related quality of life and mortality in older community-dwelling womenAm J Gastroenterol20131081152115823670115
  • GnjidicDHilmerSNBlythFMPolypharmacy cutoff and outcomes: five or more medications were used to identify community-dwelling older men at risk of different adverse outcomesJ Clin Epidemiol20126598999522742913
  • PernaLWahlHWMonsUSaumKUHolleczekBBrennerHCognitive impairment, all-cause and cause-specific mortality among non-demented older adultsAge Ageing20154444545125468013
  • SachsGACarterRHoltzLRCognitive impairment: an independent predictor of excess mortality: a cohort studyArch Intern Med2011155300308
  • IdlandGEngedalKBerglandAPhysical performance and 13.5-year mortality in elderly womenScand J Public Health20134110210823178925
  • De BuyserSLPetrovicMTaesYEToyeKRKaufmanJMGoemaereSPhysical function measurements predict mortality in ambulatory older menEur J Clin Invest20134337938623398295
  • StreicherMThemessl-HuberMSchindlerKESieberCCHiesmayrMVolkertDNutritionDay in nursing homes: the association of nutritional intake and nutritional interventions with 6-month mortality in malnourished residentsJ Am Med Dir Assoc20171816216827742584
  • BahatGTufanFBahatZObservational cohort study on correlates of mortality in older community-dwelling outpatients: the value of functional assessmentGeriatr Gerontol Int2015151219122625511256
  • Tabue-TeguoMKelaiditiEDemougeotLDartiguesJFVellasBCesariMFrailty index and mortality in nursing home residents in France: results from the INCUR studyJ Am Med Dir Assoc20151660360625769962
  • CabrerizoSCuadrasDGomez-BustoFArtaza-ArtabeIMarin-CiancasFMalafarinaVSerum albumin and health in older people: review and meta analysisMaturitas201581172725782627
  • KoehlerEMSannaDHansenBESerum liver enzymes are associated with all-cause mortality in an elderly populationLiver Int20143429630424219360
  • WulaningsihWHombergLGarmoHSerum lactate dehydrogenase and survival following cancer diagnosisBr J Cancer20151131389139626469834
  • LiuXHMengQHYeYHildebrandtMAGuJWuXPrognostic significance of pretreatment serum levels of albumin, LDH and total bilirubin in patients with non-metastatic breast cancerCarcinogenesis20153624324825524924
  • SearleSMitnitskiAGahbauerEAGillTMRockwoodKA standard procedure for creating a frailty indexBMC Geriatr200882418826625
  • RockwoodKMitnitskiALimits to deficit accumulation in elderly peopleMech Ageing Dev200612749449616487992
  • MatzenLEJepsenDBJesperRMasudTFunctional level at admission is a predictor of survival in older patients admitted to an acute geriatric unitBMC Geriatr2012123222731680
  • Avelino-SilvaTJFarfelJMCuriatiJAAmaralJRCamporaFJacob-FilhoWComprehensive geriatric assessment predicts mortality and adverse outcomes in hospitalized older adultsBMC Geriatr20141412925464932
  • TheouOCannLBlodgettJWallaceLMBrothersTDRockwoodKModifications of the frailty phenotype criteria: systematic review of the current literature and investigation of 262 frailty phenotypes in the survey of health, ageing, and retirement in EuropeAgeing Res Rev201521789425846451
  • MulassoARoppoloMGiannottaFRabagliettiEAssociations of frailty and psychosocial factors with autonomy in daily activities: a cross-sectional study in Italian community-dwelling older adultsClin Interv Aging201611374526811675