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Original Research

Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults

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Pages 1221-1230 | Published online: 21 Jul 2020

References

  • Foulke BA, Kendal AR, Murray DW, Pandit H. Fracture healing in the elderly: a review. Maturitas. 2016;92:49–55. doi:10.1016/j.maturitas.2016.07.01427621238
  • Jones G, Nguyen T, Sambrook PN, Kelly PJ, Gilbert C, Eisman JA. Symptomatic fracture incidence in elderly men and women: the Dubbo Osteoporosis Epidemiology Study (DOES). Osteoporos Int. 1994;4(5):277–282. doi:10.1007/BF16233527812076
  • Gruber R, Koch H, Doll BA, Tegtmeier F, Einhorn TA, Hollinger JO. Fracture healing in the elderly patient. Exp Gerontol. 2006;41(11):1080–1093. doi:10.1016/j.exger.2006.09.00817092679
  • Moghaddam A, Zimmermann G, Hammer K, Bruckner T, Grutzner PA, von Recum J. Cigarette smoking influences the clinical and occupational outcome of patients with tibial shaft fractures. Injury. 2011;42(12):1435–1442. doi:10.1016/j.injury.2011.05.01121665205
  • Lu C, Miclau T, Hu D, et al. Cellular basis for age-related changes in fracture repair. J Orthop Res. 2005;23(6):1300–1307. doi:10.1016/j.orthres.2005.04.003.110023061015936915
  • Egol KA, Koval KJ, Zuckerman JD. Functional recovery following hip fracture in the elderly. J Orthop Trauma. 1997;11(8):594–599. doi:10.1097/00005131-199711000-000099415867
  • Karger C, Kishi T, Schneider L, Fitoussi F, Masquelet AC. Treatment of posttraumatic bone defects by the induced membrane technique. Orthop Traumatol Surg Res. 2012;98(1):97–102. doi:10.1016/j.otsr.2011.11.00122244249
  • Bosemark P, Perdikouri C, Pelkonen M, Isaksson H, Tagil M. The masquelet induced membrane technique with BMP and a synthetic scaffold can heal a rat femoral critical size defect. J Orthop Res. 2015;33(4):488–495. doi:10.1002/jor.2281525639666
  • Masquelet AC, Begue T. The concept of induced membrane for reconstruction of long bone defects. Orthop Clin North Am. 2010;41(1):27–37. doi:10.1016/j.ocl.2009.07.01119931050
  • Pelissier P, Masquelet AC, Bareille R, Pelissier SM, Amedee J. Induced membranes secrete growth factors including vascular and osteoinductive factors and could stimulate bone regeneration. J Orthop Res. 2004;22(1):73–79. doi:10.1016/S0736-0266(03)00165-714656662
  • Moghaddam A, Zietzschmann S, Bruckner T, Schmidmaier G. Treatment of atrophic tibia non-unions according to ‘diamond concept’: results of one- and two-step treatment. Injury. 2015;46(Suppl 4):S39–50. doi:10.1016/S0020-1383(15)30017-6
  • Giannoudis PV, Einhorn TA, Marsh D. Fracture healing: the diamond concept. Injury. 2007;38(Suppl 4):S3–6. doi:10.1016/S0020-1383(08)70003-2
  • Tanner M, Vlachopoulos W, Findeisen S, et al. Does age influence the outcome of lower limb non-union treatment? A matched pair analysis. J Clin Med. 2019;8(9):1276. doi:10.3390/jcm8091276
  • Andrzejowski P, Giannoudis PV. The ‘diamond concept’ for long bone non-union management. J Orthop Traumatol. 2019;20(1):21. doi:10.1186/s10195-019-0528-030976944
  • Schmidmaier G, Moghaddam A. [Long Bone Nonunion]. Z Orthop Unfall. 2015;153(6):659–674. German. doi:10.1055/s-0035-155825926670151
  • Miska M, Findeisen S, Tanner M, et al. Treatment of nonunions in fractures of the humeral shaft according to the Diamond Concept. Bone Joint J. 2016;98-B(1):81–87. doi:10.1302/0301-620X.98B1.35682
  • Moghaddam A, Thaler B, Bruckner T, Tanner M, Schmidmaier G. Treatment of atrophic femoral non-unions according to the diamond concept: results of one- and two-step surgical procedure. J Orthop. 2017;14(1):123–133. doi:10.1016/j.jor.2016.10.00327843223
  • Haubruck P, Tanner MC, Vlachopoulos W, et al. Comparison of the clinical effectiveness of Bone Morphogenic Protein (BMP) −2 and −7 in the adjunct treatment of lower limb nonunions. Orthop Traumatol Surg Res. 2018;104(8):1241–1248. doi:10.1016/j.otsr.2018.08.00830293748
  • Haubruck P, Kammerer A, Korff S, et al. The treatment of nonunions with application of BMP-7 increases the expression pattern for angiogenic and inflammable cytokines: a matched pair analysis. J Inflamm Res. 2016;9:155–165. doi:10.2147/JIR.S11062127703392
  • Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev. 2000;21(2):115–137. doi:10.1210/edrv.21.2.039510782361
  • Fischer C, Nissen M, Schmidmaier G, Bruckner T, Kauczor HU, Weber MA. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the prediction of non-union consolidation. Injury. 2017;48(2):357–363. doi:10.1016/j.injury.2017.01.02128088373
  • Hernandez RK, Do TP, Critchlow CW, Dent RE, Jick SS. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database. Acta Orthop. 2012;83(6):653–660. doi:10.3109/17453674.2012.74705423140093
  • Masquelet AC, Obert L. [Induced membrane technique for bone defects in the hand and wrist]. Chir Main. 2010;29(Suppl 1):S221–224. French. doi:10.1016/j.main.2010.10.00721084208
  • Toksvig-Larsen AWD, Toksvig-Larsen S. Cigarette smoking delays bone healing: a prospective study of 200 patients operated on by the hemicallotasis technique. Acta Orthop Scand. 2004;75(3):347–351. doi:10.1080/0001647041000130315260429
  • Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P. Does obesity and nicotine abuse influence the outcome and complication rate after open-wedge high tibial osteotomy? A retrospective evaluation of five hundred and thirty three patients. Int Orthop. 2014;38(1):55–60. doi:10.1007/s00264-013-2082-324022738
  • Chapman IM. Obesity in old age. Front Horm Res. 2008;36:97–106.18230897
  • Wojzischke J, Diekmann R, Bauer JM. [Obesity in old age and its importance for functionality and frailty]. Z Gerontol Geriatr. 2016;49(7):573–580. German. doi:10.1007/s00391-016-1133-y27637579
  • Mathus-Vliegen EM. Obesity and the elderly. J Clin Gastroenterol. 2012;46(7):533–544. doi:10.1097/MCG.0b013e31825692ce22772735
  • Vallier HA, Cureton BA, Patterson BM. Randomized, prospective comparison of plate versus intramedullary nail fixation for distal tibia shaft fractures. J Orthop Trauma. 2011;25(12):736–741. doi:10.1097/BOT.0b013e318213f70921904230