Efficacy and safety of lenalidomide for the treatment of acute myeloid leukemia: a systematic review and meta-analysis

References

• SiegelRLMillerKDJemalACancer Statistics, 2017CA Cancer J Clin201767173028055103
   PubMed Web of Science ®Google Scholar
• LeopoldLHWillemzeRThe treatment of acute myeloid leukemia in first relapse: a comprehensive review of the literatureLeuk Lymphoma20024391715172712685823
   PubMed Web of Science ®Google Scholar
• LöwenbergBDowningJRBurnettAAcute myeloid leukemiaN Engl J Med1999341141051106210502596
   PubMed Web of Science ®Google Scholar
• StoneRMThe difficult problem of acute myeloid leukemia in the older adultCA Cancer J Clin200252636337112469764
   PubMed Web of Science ®Google Scholar
• National Cancer InstituteSEER Stat Fact Sheets: Acute Myeloid Leukemia (AML) Available from: http://seer.cancer.gov/statfacts/html/amyl.htmlAccessed December 29, 2017
   Google Scholar
• KlepinHDElderly acute myeloid leukemia: assessing riskCurr Hematol Malig Rep201510211812525939828
   PubMed Web of Science ®Google Scholar
• BurnettAWetzlerMLöwenbergBTherapeutic advances in acute myeloid leukemiaJ Clin Oncol201129548749421220605
   PubMed Web of Science ®Google Scholar
• GuptaVTallmanMSWeisdorfDJAllogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknownsBlood201111782307231821098397
   PubMed Web of Science ®Google Scholar
• KorethJSchlenkRKopeckyKJAllogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: systematic review and meta-analysis of prospective clinical trialsJAMA2009301222349236119509382
   PubMed Web of Science ®Google Scholar
• BasaraNSchulzeAWeddingUEarly related or unrelated haematopoietic cell transplantation results in higher overall survival and leukaemia-free survival compared with conventional chemotherapy in high-risk acute myeloid leukaemia patients in first complete remissionLeukemia200923463564019151786
   PubMed Web of Science ®Google Scholar
• GuptaVTallmanMSHeWComparable survival after HLA-well- matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosisBlood2010116111839184820538804
   PubMed Web of Science ®Google Scholar
• DombretHRaffouxEGardinCNew insights in the management of elderly patients with acute myeloid leukemiaCurr Opin Oncol200921658959319812493
   PubMed Web of Science ®Google Scholar
• DöhnerHWeisdorfDJBloomfieldCDAcute myeloid leukemiaN Engl J Med2015373121136115226376137
   PubMed Web of Science ®Google Scholar
• EsteyEAcute myeloid leukemia and myelodysplastic syndromes in older patientsJ Clin Oncol200725141908191517488990
   PubMed Web of Science ®Google Scholar
• DohnerHEsteyEHAmadoriSDiagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European Leukemia NetBlood201011545347419880497
   PubMed Web of Science ®Google Scholar
• LangKEarleCCFosterTTrends in the treatment of acute myeloid leukaemia in the elderlyDrugs Aging2005221194395516323971
   PubMed Web of Science ®Google Scholar
• ChenYBorthakurGLenalidomide as a novel treatment of acute myeloid leukemiaExpert Opin Investig Drugs2013223389397
   PubMed Web of Science ®Google Scholar
• BlumWKlisovicRBBeckerHDose escalation of lenalidomide in relapsed or refractory acute leukemiasJ Clin Oncol201028334919492520956622
   PubMed Web of Science ®Google Scholar
• FehnigerTAUyGLTrinkausKA phase 2 study of high-dose lenalidomide as initial therapy for older patients with acute myeloid leukemiaBlood201111761828183321051557
   PubMed Web of Science ®Google Scholar
• MedeirosBCMccaulKKambhampatiSRandomized study of continuous high-dose lenalidomide, sequential azacitidine and lenalidomide, or azacitidine in persons 65 years and over with newly-diagnosed acute myeloid leukemiaHaematologica2018103110110629097499
   PubMed Web of Science ®Google Scholar
• HigginsJPTGreenSCochrane Handbook for Systematic Reviews of Interventions Version 5.1.0The Cochrane Collaboration2011 Available from: http://handbook.cochrane.orgLast accessed September 7, 2018
   Google Scholar
• ChesonBDGreenbergPLBennettJMClinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasiaBlood2006108241942516609072
   PubMed Web of Science ®Google Scholar
• ChesonBDBennettJMKopeckyKJRevised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid LeukemiaJ Clin Oncol200321244642464914673054
   PubMed Web of Science ®Google Scholar
• WellsGSheaBO’ConnellDThe Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta–analysis Available from: http://www.ohri.ca/programs/clinical_epidemiology/oxfordAccessed December 29, 2017
   Google Scholar
• NarayanRGarciaJSPercivalMESequential azacitidine plus lenalidomide in previously treated elderly patients with acute myeloid leukemia and higher risk myelodysplastic syndromeLeuk Lymphoma201657360961526374199
   PubMed Web of Science ®Google Scholar
• PollyeaDAKohrtHEGallegosLSafety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemiaLeukemia201226589390122033493
   PubMed Web of Science ®Google Scholar
• PollyeaDAZehnderJCoutreSSequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemiaHaematologica201398459159623242596
   PubMed Web of Science ®Google Scholar
• RamsinghGWesterveltPCashenAFA phase 1 study of concomitant high-dose lenalidomide and 5-azacitidine induction in the treatment of AMLLeukemia201327372572822828444
   PubMed Web of Science ®Google Scholar
• SekeresMAGundackerHLancetJA phase 2 study of lenalidomide monotherapy in patients with deletion 5q acute myeloid leukemia: Southwest Oncology Group Study S0605Blood2011118352352821551228
   PubMed Web of Science ®Google Scholar
• GriffithsEABradyWETanWA phase I study of intermediate dose cytarabine in combination with lenalidomide in relapsed/refractory acute myeloid leukemiaLeuk Res201643444826943703
   PubMed Web of Science ®Google Scholar
• VisaniGFerraraFdi RaimondoFLow-dose lenalidomide plus cytarabine induce complete remission that can be predicted by genetic profiling in elderly acute myeloid leukemia patientsLeukemia201428496797024441289
   PubMed Web of Science ®Google Scholar
• VisaniGFerraraFdi RaimondoFLow-dose lenalidomide plus cytarabine in very elderly, unfit acute myeloid leukemia patients: Final result of a phase II studyLeuk Res201762778328987821
   PubMed Web of Science ®Google Scholar
• DombretHSeymourJFButrymAInternational phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with 30% blastsBlood2015126329129925987659
   PubMed Web of Science ®Google Scholar
• HickeyCJSchwindSRadomskaHSLenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemiaBlood2013121115916923100311
   PubMed Web of Science ®Google Scholar
• MarcucciGRadmacherMDMaharryKMicroRNA expression in cytogenetically normal acute myeloid leukemiaN Engl J Med2008358181919192818450603
   PubMed Web of Science ®Google Scholar
• LiZHuangHLiYUp-regulation of a HOXA-PBX3 homeoboxgene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AMLBlood2012119102314232422251480
   PubMed Web of Science ®Google Scholar
• SchwindSMaharryKRadmacherMDPrognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B studyJ Clin Oncol201028365257526421079133
   PubMed Web of Science ®Google Scholar
• DöhnerHEsteyEHAmadoriSDiagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNetBlood2010115345347419880497
   PubMed Web of Science ®Google Scholar
• MarcucciGHaferlachTDöhnerHMolecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implicationsJ Clin Oncol201129547548621220609
   PubMed Web of Science ®Google Scholar