Uridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway

References

• SiegelRLMillerKDJemalACancer statistics, 2015CA Cancer J Clin201565152925559415
   PubMed Web of Science ®Google Scholar
• ChenWZhengRBaadePDCancer statistics in China, 2015CA Cancer J Clin201666211513226808342
   PubMed Web of Science ®Google Scholar
• GohGBChangPETanCKChanging epidemiology of hepatocellular carcinoma in AsiaBest Pract Res Clin Gastroenterol201529691992826651253
   PubMed Web of Science ®Google Scholar
• LaneANFanTWRegulation of mammalian nucleotide metabolism and biosynthesisNucleic Acids Res20154342466248525628363
   PubMed Web of Science ®Google Scholar
• TomoikeFNakagawaNFukuiKIndispensable residue for uridine binding in the uridine-cytidine kinase familyBiochem Biophys Rep201711939828955773
   PubMedGoogle Scholar
• van RompayARNordaALindénKJohanssonMKarlssonAPhosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinasesMol Pharmacol20015951181118611306702
   PubMed Web of Science ®Google Scholar
• MuhaleFAWetmoreBAThomasRSMcleodHLSystems pharmacology assessment of the 5-fluorouracil pathwayPharmacogenomics201112334135021449674
   PubMed Web of Science ®Google Scholar
• MurataDEndoYObataTA crucial role of uridine/cytidine kinase 2 in antitumor activity of 3’-ethynyl nucleosidesDrug Metab Dispos200432101178118215280220
   PubMed Web of Science ®Google Scholar
• SatoATakanoTHiramotoARole of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3’-ethynylcytidine treatment of human cancer cellsAnticancer Drugs201728778178628542039
   PubMed Web of Science ®Google Scholar
• ShenGHePMaoYOverexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor PrognosisJ Breast Cancer201720213214128690649
   PubMed Web of Science ®Google Scholar
• AggarwalBBKunnumakkaraABHarikumarKBSignal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?Ann N Y Acad Sci20091171597619723038
   PubMed Web of Science ®Google Scholar
• RajendranPOngTHChenLSuppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivoClin Cancer Res20111761425143921131551
   PubMed Web of Science ®Google Scholar
• SubramaniamAShanmugamMKOngTHEmodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3Br J Pharmacol2013170480782123848338
   PubMed Web of Science ®Google Scholar
• WangSWSunYMThe IL-6/JAK/STAT3 pathway: potential therapeutic strategies in treating colorectal cancer (Review)Int J Oncol20144441032104024430672
   PubMed Web of Science ®Google Scholar
• RhodesDRYuJShankerKONCOMINE: a cancer micro-array database and integrated data-mining platformNeoplasia2004611615068665
   PubMed Web of Science ®Google Scholar
• ChenXCheungSTSoSGene expression patterns in human liver cancersMol Biol Cell20021361929193912058060
   PubMed Web of Science ®Google Scholar
• RoesslerSJiaHLBudhuAA unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patientsCancer Res20107024102021021221159642
   PubMed Web of Science ®Google Scholar
• EgebladMWerbZNew functions for the matrix metalloproteinases in cancer progressionNat Rev Cancer20022316117411990853
   PubMed Web of Science ®Google Scholar
• TaniaMKhanMAFuJEpithelial to mesenchymal transition inducing transcription factors and metastatic cancerTumour Biol20143587335734224880591
   PubMedGoogle Scholar
• ZeisbergMNeilsonEGBiomarkers for epithelial-mesenchymal transitionsJ Clin Invest200911961429143719487819
   PubMed Web of Science ®Google Scholar
• GronerBLucksPBorghoutsCThe function of Stat3 in tumor cells and their microenvironmentSemin Cell Dev Biol200819434135018621135
   PubMed Web of Science ®Google Scholar
• WeiZJiangXQiaoHSTAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cellsCell Signal201325493193823333463
   PubMed Web of Science ®Google Scholar
• BanerjeeKResatHConstitutive activation of STAT3 in breast cancer cells: A reviewInt J Cancer2016138112570257826559373
   PubMed Web of Science ®Google Scholar
• WendtMKBalanisNCarlinCRSTAT3 and epithelial-mesenchymal transitions in carcinomasJAKSTAT201431e2897524843831
   PubMedGoogle Scholar
• XiongHHongJduWRoles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transitionJ Biol Chem201228785819583222205702
   PubMed Web of Science ®Google Scholar
• ChenJLanTZhangWFeed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial-Mesenchymal Transition in Non-Small Cell Lung CancerCancer Res201575194198421026359459
   PubMed Web of Science ®Google Scholar
• YuanMGuoHLiJSlit2 and Robo1 induce opposing effects on metastasis of hepatocellular carcinoma Sk-hep-1 cellsInt J Oncol201649130531527176045
   PubMed Web of Science ®Google Scholar
• KessenbrockKPlaksVWerbZMatrix metalloproteinases: regulators of the tumor microenvironmentCell20101411526720371345
   PubMed Web of Science ®Google Scholar
• ThieryJPAcloqueHHuangRYNietoMAEpithelial-mesenchymal transitions in development and diseaseCell2009139587189019945376
   PubMed Web of Science ®Google Scholar
• SubramaniamAShanmugamMKPerumalEPotential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinomaBiochim Biophys Acta201318351466023103770
   PubMed Web of Science ®Google Scholar
• CourapiedSSellierHde Carné TrécessonSThe cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibitionJ Biol Chem201028535267652677820516069
   PubMed Web of Science ®Google Scholar
• XieTXWeiDLiuMStat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasisOncogene200423203550356015116091
   PubMed Web of Science ®Google Scholar
• SongYQianLSongSFra-1 and Stat3 synergistically regulate activation of human MMP-9 geneMol Immunol200845113714317572495
   PubMed Web of Science ®Google Scholar