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Original Research

Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo

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Pages 5883-5894 | Published online: 28 Jun 2019

References

  • Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893–2917. doi:10.1002/ijc.2551621351269
  • El-Serag HB. Hepatocellular carcinoma. Hepat Mon. 2011;11(2):69–70. 22087121
  • Fitzmaurice C, Dicker D, Pain A, et al. The global burden of cancer 2013. JAMA Oncol. 2015;1(4):505. doi:10.1001/jamaoncol.2015.073526181261
  • Trojan J, Zangos S, Schnitzbauer AA. Diagnostics and treatment of hepatocellular carcinoma in 2016: standards and developments. Viszeralmedizin. 2016;32(2):116–120.
  • Yang C, Jian P, Chen J. Identification of potential gene network associated with HCV-related hepatocellular carcinoma using microarray analysis. Pathol Oncol Res. 2017;24(3):1–8. 28160197
  • Llovet JM, Zucman-Rossi J, Pikarsky E, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2016;2:16018. doi:10.1038/nrdp.2016.1827158749
  • Cervello M, Mccubrey JA, Cusimano A, et al. Targeted therapy for hepatocellular carcinoma: novel agents on the horizon. Oncotarget. 2012;3(3):236–260. doi:10.18632/oncotarget.46622470194
  • Morise Z, Kawabe N, Tomishige H, et al. Recent advances in liver resection for hepatocellular carcinoma. Front Surg. 2014;1:21. doi:10.3389/fsurg.2014.0002125593945
  • Yu Y, Shen H, Yu H, et al. Systematic proteomic analysis of human hepotacellular carcinoma cells reveals molecular pathways and networks involved in metastasis. Mol Biosyst. 2011;7(6):1908–1916. doi:10.1039/c0mb00265h21468425
  • Perlikos F, Harrington KJ, Syrigos KN. Key molecular mechanisms in lung cancer invasion and metastasis: a comprehensive review. Crit Rev Oncol Hematol. 2013;87(1):1–11. doi:10.1016/j.critrevonc.2012.12.00723332547
  • Orlichenko LS, Radisky DC. Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development. Clin Exp Metastasis. 2008;25(6):593–600. doi:10.1007/s10585-008-9143-918286378
  • Twilley D, Lall N. Chapter 7 – the role of natural products from plants in the development of anticancer agents. Nat Rev Drug Discovery. 2018;1:139–178.
  • Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014;7(6):421–428. doi:10.1016/S1995-7645(14)60069-925066389
  • Kiso Y, Tohkin M, Hikino H. Antihepatotoxic principles of atractylodes rhizomes. J Nat Prod. 1983;46(5):651. doi:10.1021/np50029a0106418860
  • Kiso Y, Tohkin M, Hikino H. Mechanism of antihepatotoxic activity of atractylon, I: effect on free radical generation and lipid peroxidation. Planta Med. 1985;51(2):97–100. doi:10.1055/s-2007-969416
  • Hwang JM, Tseng TH, Hsieh YS, et al. Inhibitory effect of atractylon on tert-butyl hydroperoxide induced DNA damage and hepatic toxicity in rat hepatocytes. Arch Toxicol. 1996;70(10):640–644. 8870957
  • Satoh K, Nagai F, Ushiyama K, Kano I. Specific inhibition of Na+,K(+)-ATPase activity by atractylon, a major component of byaku-jutsu, by interaction with enzyme in the E2 state. Biochem Pharmacol. 1996;51(3):339. doi:10.1016/0006-2952(95)02188-48573201
  • Yang C, Mai JY, Hou TL, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016;14(4):3704–3710. doi:10.3892/mmr.2016.571327600871
  • Chen LG, Jan Y, Tsai P, et al. Anti-inflammatory and antinociceptive constituents of Atractylodes japonica Koidzumi. J Agric Food Chem. 2016;64:11.
  • Yu S, Yasukawa K, Takido M. Atractylodis Rhizoma extract and its component, atractylon, inhibit tumor promotion in mouse skin two-stage carcinogenesis. Phytomedicine. 1994;1(1):55. doi:10.1016/S0944-7113(11)80023-123195816
  • Xiong Y, Ye T, Wang M, et al. A novel cinnamide YLT26 induces breast cancer cells Apoptosis via ROS-mitochondrial apoptotic pathway in vitro and inhibits lung metastasis in vivo. Cell Physiol Biochem. 2014;34(6):1863–1876. doi:10.1159/00036638525503322
  • Finkel T. Signal transduction by reactive oxygen species in non-phagocytic cells. J Leukoc Biol. 1999;65(3):337–340. doi:10.1002/jlb.65.3.33710080536
  • Zhang T, Li J, Dong Y, et al. Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion. Breast Cancer Res Treat. 2012;135(2):445–458. doi:10.1007/s10549-012-2175-522842972
  • Thiery JP, Acloque H, Huang RYJ, et al. Epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871–890. doi:10.1016/j.cell.2009.11.00719945376
  • Bhuvarahamurthy V, Kristiansen GO, Johannsen M, et al. In situ gene expression and localization of metalloproteinases MMP1, MMP2, MMP3, MMP9, and their inhibitors TIMP1 and TIMP2 in human renal cell carcinoma. Oncol Rep. 2006;15(5):1379. 16596214
  • Indran IR, Tufo G, Pervaiz S, et al. Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochim Biophys Acta. 2011;1807(6):735–745. doi:10.1016/j.bbabio.2011.03.01021453675
  • Ly JD, Grubb DR, Lawen A. The mitochondrial membrane potential (Δψm) in apoptosis; an update. Apoptosis. 2003;8(2):115–128. 12766472
  • Chung YM, Bae YS, Lee SY. Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. Free Radic Biol Med. 2003;34(4):434–442. doi:10.1016/S0891-5849(02)01301-112566069
  • Dewson G, Kluck RM. Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis. J Cell Sci. 2009;122(16):2801–2808. 19795525
  • Tsai JH, Yang J. Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev. 2013;27(20):2192–2206. doi:10.1101/gad.225334.11324142872
  • Jin K, Gao W, Lu Y, et al. Mechanisms regulating colorectal cancer cell metastasis into liver (Review). Oncol Lett. 2012;3(1):11–15. doi:10.3892/ol.2011.43222740847
  • Deryugina EI, Quigley JP. Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature. Matrix Biol. 2015;44–46:94–112. doi:10.1016/j.matbio.2015.04.004
  • Kai K, Wang CY, Werb Z. Matrix metalloproteinases in stem cell regulation and cancer. Matrix Biol. 2015;44–46(46):184–190. doi:10.1016/j.matbio.2015.01.022