Voltage-dependent calcium channel α2δ1 subunit is a specific candidate marker for identifying gastric cancer stem cells

References

• Wagner AD, Syn NL, Moehler M, et al. Chemotherapy for advanced gastric cancer. Cochrane Database Syst Rev. 2017;8:CD004064.28850174
   PubMed Web of Science ®Google Scholar
• Guggenheim DE, Shah MA. Gastric cancer epidemiology and risk factors. J Surg Oncol. 2013;107(3):230–236. doi:10.1002/jso.2326223129495
   PubMed Web of Science ®Google Scholar
• Van Cutsem E, Sagaert X, Topal B, Haustermans K, Prenen H. Gastric cancer. Lancet. 2016;388(10060):2654–2664. doi:10.1016/S0140-6736(16)30354-327156933
   PubMed Web of Science ®Google Scholar
• Pattabiraman DR, Weinberg RA. Tackling the cancer stem cells - what challenges do they pose? Nat Rev Drug Discov. 2014;13(7):497–512. doi:10.1038/nrd425324981363
   PubMed Web of Science ®Google Scholar
• Takaishi S, Okumura T, Tu S, et al. Identification of gastric cancer stem cells using the cell surface marker CD44. Stem Cells. 2009;27(5):1006–1020. doi:10.1002/stem.3019415765
   PubMed Web of Science ®Google Scholar
• Qiao XT, Ziel JW, McKimpson W, et al. Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology. 2007;133(6):1989–1998. doi:10.1053/j.gastro.2007.09.03118054570
   PubMed Web of Science ®Google Scholar
• Richard V, Nair MG, Santhosh Kumar TR, Pillai MR. Side population cells as prototype of chemoresistant, tumor-initiating cells. Biomed Res Int. 2013;2013:517237 Epub 2013 Nov 4. doi:10.1155/2013/517237.24294611
   PubMed Web of Science ®Google Scholar
• Siddique HR, Saleem M. Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences. Stem Cells. 2012;30(3):372–378. doi:10.1002/stem.103522252887
   PubMed Web of Science ®Google Scholar
• Varga J, Greten FR. Lifting the mist on gastric stem cells. Cell Stem Cell. 2016;18(1):7–9. doi:10.1016/j.stem.2015.12.00826748749
   PubMed Web of Science ®Google Scholar
• Leushacke M, Tan SH, Wong A, et al. Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach. Nat Cell Biol. 2017;19(7):774–786. doi:10.1038/ncb345028581476
   PubMed Web of Science ®Google Scholar
• Zhao Y, Feng F, Zhou YN. Stem cells in gastric cancer. World J Gastroenterol. 2015;21(1):112–123. doi:10.3748/wjg.v21.i1.11225574084
   PubMed Web of Science ®Google Scholar
• Park JW, Park JM, Park DM, Kim DY, Kim HK. Stem cells antigen-1 enriches for a cancer stem cell-like subpopulation in mouse gastric cancer. Stem Cells. 2016;34(5):1177–1187. doi:10.1053/j.gastro.2007.09.03126869189
   PubMed Web of Science ®Google Scholar
• Rassouli FB, Matin MM, Saeinasab M. Cancer stem cells in human digestive tract malignancies. Tumour Biol. 2016;37(1):7–21. doi:10.1007/s13277-015-4155-y26446457
   PubMedGoogle Scholar
• Hoffmann W. Current status on stem cells and cancers of the gastric epithelium. Int J Mol Sci. 2015;16(8):19153–19169. doi:10.3390/ijms16081915326287172
   PubMed Web of Science ®Google Scholar
• Nguyen PH, Giraud J, Chambonnier L, et al. Characterization of biomarkers of tumorigenic and chemoresistant cancer stem cells in human gastric carcinoma. Clin Cancer Res. 2017;23(6):1586–1597. doi:10.1158/1078-0432.CCR-15-215727620279
   PubMed Web of Science ®Google Scholar
• Qiao XT, Gumucio D. Current molecular markers for gastric progenitor cells and gastric cancer stem cells. J Gastroenterol. 2011;46(7):855–865. doi:10.1007/s00535-011-0413-y21626457
   PubMed Web of Science ®Google Scholar
• Wang T, Shigdar S, Gantier MP, et al. Cancer stem cell targeted therapy: progress amid controversies. Oncotarget. 2015;6(42):44191–44206.26496035
   PubMedGoogle Scholar
• Zhao W, Wang L, Han H, et al. 1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit. Cancer Cell. 2013;23(4):541–556. doi:10.1016/j.ccr.2013.02.02523597567
   PubMed Web of Science ®Google Scholar
• Yu J, Wang S, Zhao W, et al. Mechanistic exploration of cancer stem cell marker voltage-dependent calcium channel α2δ1 subunit-mediated chemotherapy resistance in small-cell lung cancer. Clin Cancer Res. 2018;24(9):2148–2158. doi:10.1158/1078-0432.CCR-17-193229437792
   PubMed Web of Science ®Google Scholar
• Akagi T, Kimoto T. Human cell line (HGC-27) derived from the metastatic lymph node of gastric cancer. Acta Med Okayama. 1976;30(3):215–219.136873
   PubMed Web of Science ®Google Scholar
• Zhu Y, Tian T, Li Z, et al. Establishment and characterization of patient-derived tumor xenograft using gastroscopic biopsies in gastric cancer. Sci Rep. 2015;5:8542. doi:10.1038/srep0854225712750
   PubMed Web of Science ®Google Scholar
• Singh SR. Gastric cancer stem cells: a novel therapeutic target. Cancer Lett. 2013;338(1):110–119. doi:10.1016/j.canlet.2013.03.03423583679
   PubMed Web of Science ®Google Scholar
• Clarke MF, Dick JE, Dirks PB, et al. Cancer stem cells–perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res. 2006;66(19):9339–9344. Epub 2006 Sep 21. doi:10.1158/0008-5472.CAN-06-3126.16990346
   PubMedGoogle Scholar
• Chiba T, Miyagi S, Saraya A, et al. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Res. 2008;68(19):7742–7749. doi:10.1158/0008-5472.CAN-07-588218829528
   PubMed Web of Science ®Google Scholar
• Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 1997;3(7):730–737.9212098
   PubMed Web of Science ®Google Scholar
• Zeppernick F, Ahmadi R, Campos B, et al. Stem cell marker CD133 affects clinical outcome in glioma patients. Clin Cancer Res. 2008;14(1):123–129. doi:10.1158/1078-0432.CCR-07-093218172261
   PubMed Web of Science ®Google Scholar
• Cao L, Zhou Y, Zhai B, et al. Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines. BMC Gastroenterol. 2011;11:71. doi:10.1186/1471-230X-11-9321669008
   PubMed Web of Science ®Google Scholar
• Lv C, Li F, Li X, et al. MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists. Nat Commun. 2017;8(1):1036. doi:10.1038/s41467-017-01059-529051494
   PubMedGoogle Scholar
• de Sousa e Melo F, Av K, Jm H, et al. A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer. Nature. 2017;543(7647):676–680. doi:10.1038/nature2171328358093
   PubMed Web of Science ®Google Scholar
• Batlle E, Clevers H. Cancer stem cells revisited. Nat Med. 2017;23(10):1124–1134. doi:10.1038/nm.426528985214
   PubMed Web of Science ®Google Scholar
• Talukdar S, Emdad L, Das SK, Sarkar D, Fisher PB. Evolving strategies for therapeutically targeting cancer stem cells. Adv Cancer Res. 2016;131:159–191.27451127
   PubMed Web of Science ®Google Scholar
• Singh SK, Clarke ID, Terasaki M. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63(18):5821–5828.14522905
   PubMed Web of Science ®Google Scholar
• Hansford LM, McKee AE, Zhang L, et al. Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell. Cancer Res. 2007;67(23):11234–11243. doi:10.1158/0008-5472.CAN-07-071818056449
   PubMed Web of Science ®Google Scholar
• Yan Y, Zuo X, Wei D. Concise review: emerging role of CD44 in cancer stem cells: a promising biomarker and therapeutic target. Stem Cells Transl Med. 2015;4(9):1033–1043. doi:10.5966/sctm.2015-004826136504
   PubMed Web of Science ®Google Scholar
• Rosen JM, Jordan CT. The increasing complexity of the cancer stem cell paradigm. Science. 2009;324(5935):1670–1673. doi:10.1126/science.117183719556499
   PubMed Web of Science ®Google Scholar
• Hu Y, Smyth GK. ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J Immunol Methods. 2009;347(1–2):70–78. doi:10.1016/j.jim.2009.06.00819567251
   PubMed Web of Science ®Google Scholar