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Original Research

Cervical Cancer Cells-Secreted Exosomal microRNA-221-3p Promotes Invasion, Migration and Angiogenesis of Microvascular Endothelial Cells in Cervical Cancer by Down-Regulating MAPK10 Expression

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Pages 10307-10319 | Published online: 09 Dec 2019

References

  • Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet. 2019;393(10167):169–182. doi:10.1016/S0140-6736(18)32470-X30638582
  • Vaccarella S, Franceschi S, Zaridze D, et al. Preventable fractions of cervical cancer via effective screening in six Baltic, central, and eastern European countries 2017-40: a population-based study. Lancet Oncol. 2016;17(10):1445–1452. doi:10.1016/S1470-2045(16)30275-327567054
  • Steenbergen RD, Snijders PJ, Heideman DA, Meijer CJ. Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions. Nat Rev Cancer. 2014;14(6):395–405. doi:10.1038/nrc372824854082
  • Stevanovic S, Draper LM, Langhan MM, et al. Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells. J Clin Oncol. 2015;33(14):1543–1550. doi:10.1200/JCO.2014.58.909325823737
  • Castiglioni S, Caspani C, Cazzaniga A, Maier JA. Short- and long-term effects of silver nanoparticles on human microvascular endothelial cells. World J Biol Chem. 2014;5(4):457–464. doi:10.4331/wjbc.v5.i4.45725426268
  • Xu ZH, Miao ZW, Jiang QZ, et al. Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain. Faseb J. 2019;33(2):1742–1757. doi:10.1096/fj.201800428R30183374
  • Thind A, Wilson C. Exosomal miRNAs as cancer biomarkers and therapeutic targets. J Extracell Vesicles. 2016;5:31292. doi:10.3402/jev.v5.3129227440105
  • Li X, Corbett AL, Taatizadeh E, et al. Challenges and opportunities in exosome research-Perspectives from biology, engineering, and cancer therapy. APL Bioeng. 2019;3(1):011503. doi:10.1063/1.508712231069333
  • Bhat A, Sharma A, Bharti AC. Upstream Hedgehog signaling components are exported in exosomes of cervical cancer cell lines. Nanomedicine (Lond). 2018;13(17):2127–2138. doi:10.2217/nnm-2018-014330265222
  • Shi B, Wang Y, Zhao R, Long X, Deng W, Wang Z. Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit+ cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis. PLoS One. 2018;13(2):e0191616. doi:10.1371/journal.pone.019161629444190
  • Liu SS, Chan KKL, Chu DKH, et al. Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer. Mol Oncol. 2018;12(12):2009–2022. doi:10.1002/1878-0261.1238330221475
  • Zhou CF, Ma J, Huang L, et al. Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH1. Oncogene. 2019;38(8):1256–1268. doi:10.1038/s41388-018-0511-x30254211
  • Kunde SA, Rademacher N, Tzschach A, et al. Characterisation of de novo MAPK10/JNK3 truncation mutations associated with cognitive disorders in two unrelated patients. Hum Genet. 2013;132(4):461–471. doi:10.1007/s00439-012-1260-523329067
  • Yoo KH, Park YK, Kim HS, Jung WW, Chang SG. Identification of MAPK10 as a novel epigenetic marker for chromophobe kidney cancer. Pathol Int. 2011;61(1):52–54. doi:10.1111/j.1440-1827.2010.02605.x21166945
  • Tang BB, Liu SY, Zhan YU, et al. microRNA-218 expression and its association with the clinicopathological characteristics of patients with cervical cancer. Exp Ther Med. 2015;10(1):269–274. doi:10.3892/etm.2015.245526170947
  • Liu J, Sun H, Wang X, et al. Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer. Int J Mol Sci. 2014;15(1):758–773. doi:10.3390/ijms1501075824406730
  • Zhang B, Wu X, Zhang X, et al. Human umbilical cord mesenchymal stem cell exosomes enhance angiogenesis through the Wnt4/beta-catenin pathway. Stem Cells Transl Med. 2015;4(5):513–522. doi:10.5966/sctm.2014-026725824139
  • Sharafeldin N, Slattery ML, Liu Q, et al. Multiple gene-environment interactions on the angiogenesis gene-pathway impact rectal cancer risk and survival. Int J Environ Res Public Health. 2017;14:10. doi:10.3390/ijerph14101146
  • Wu Y, Zhou BP. TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer. 2010;102(4):639–644. doi:10.1038/sj.bjc.660553020087353
  • Rosa MN, Evangelista AF, Leal LF, et al. Establishment, molecular and biological characterization of HCB-514: a novel human cervical cancer cell line. Sci Rep. 2019;9(1):1913. doi:10.1038/s41598-018-38315-730760827
  • Zhang D, Lee H, Zhu Z, Minhas JK, Jin Y. Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2017;312(1):L110–L121. doi:10.1152/ajplung.00423.201627881406
  • Li F, Xu JW, Wang L, Liu H, Yan Y, Hu SY. MicroRNA-221-3p is up-regulated and serves as a potential biomarker in pancreatic cancer. Artif Cells Nanomed Biotechnol. 2018;46(3):482–487. doi:10.1080/21691401.2017.131542928434388
  • Zhou X, Wen W, Shan X, et al. A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis. Oncotarget. 2017;8(4):6513–6525. doi:10.18632/oncotarget.1431128036284
  • Petrozza V, Pastore AL, Palleschi G, et al. Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma. Oncotarget. 2017;8(41):69551–69558. doi:10.18632/oncotarget.v8i4129050224
  • Wei WF, Zhou CF, Wu XG, et al. MicroRNA-221-3p, a TWIST2 target, promotes cervical cancer metastasis by directly targeting THBS2. Cell Death Dis. 2017;8(12):3220. doi:10.1038/s41419-017-0077-529242498
  • Ying J, Li H, Cui Y, Wong AH, Langford C, Tao Q. Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter. Leukemia. 2006;20(6):1173–1175. doi:10.1038/sj.leu.240419316572203
  • Li L, Luo Z. Dysregulated miR-27a-3p promotes nasopharyngeal carcinoma cell proliferation and migration by targeting Mapk10. Oncol Rep. 2017;37(5):2679–2687. doi:10.3892/or.2017.554428393229
  • Zhao L, Zou D, Wei X, et al. MiRNA-221-3p desensitizes pancreatic cancer cells to 5-fluorouracil by targeting RB1. Tumour Biol. 2016;37:16053–16063. doi:10.1007/s13277-016-5445-8
  • Mahata S, Bharti AC, Shukla S, Tyagi A, Husain SA, Das BC. Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. Mol Cancer. 2011;10:39. doi:10.1186/1476-4598-10-3921496227
  • Shojaei F, Wu X, Malik AK, et al. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat Biotechnol. 2007;25(8):911–920. doi:10.1038/nbt132317664940
  • Hammes LS, Tekmal RR, Naud P, et al. Up-regulation of VEGF, c-fms and COX-2 expression correlates with severity of cervical cancer precursor (CIN) lesions and invasive disease. Gynecol Oncol. 2008;110(3):445–451. doi:10.1016/j.ygyno.2008.04.03818565574
  • de Conti A, Ortega JF, Tryndyak V, et al. MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis. Oncotarget. 2017;8(51):88517–88528. doi:10.18632/oncotarget.v8i5129179453
  • Peng Q, Deng Z, Pan H, Gu L, Liu O, Tang Z. Mitogen-activated protein kinase signaling pathway in oral cancer. Oncol Lett. 2018;15(2):1379–1388. doi:10.3892/ol.2017.749129434828
  • Whitmarsh AJ, Davis RJ. Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene. 2007;26(22):3172–3184. doi:10.1038/sj.onc.121041017496914
  • Cheng MJ, Cao YG. TMPYP4 exerted antitumor effects in human cervical cancer cells through activation of p38 mitogen-activated protein kinase. Biol Res. 2017;50(1):24. doi:10.1186/s40659-017-0129-428673331
  • Melo SA, Sugimoto H, O’Connell JT, et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 2014;26(5):707–721. doi:10.1016/j.ccell.2014.09.00525446899
  • Yan W, Wu X, Zhou W, et al. Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells. Nat Cell Biol. 2018;20(5):597–609. doi:10.1038/s41556-018-0083-629662176
  • Sun X, Ma X, Wang J, et al. Glioma stem cells-derived exosomes promote the angiogenic ability of endothelial cells through miR-21/VEGF signal. Oncotarget. 2017;8(22):36137–36148. doi:10.18632/oncotarget.1666128410224
  • Wu XG, Zhou CF, Zhang YM, et al. Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma. Angiogenesis. 2019;22:397–410. doi:10.1007/s10456-019-09665-130993566