circPCNX and Pecanex Promote Hepatocellular Carcinoma Cell Viability by Inhibiting miR-506

References

• Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62:10–29. doi:10.3322/caac.2013822237781
   PubMed Web of Science ®Google Scholar
• Llovet JM, Zucman-Rossi J, Pikarsky E, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2016;2:16018. doi:10.1038/nrdp.2016.1827158749
   PubMed Web of Science ®Google Scholar
• Poon RT. Differentiating early and late recurrences after resection of HCC in cirrhotic patients: implications on surveillance, prevention, and treatment strategies. Ann Surg Oncol. 2009;16:792–794. doi:10.1245/s10434-009-0330-y19190964
   PubMed Web of Science ®Google Scholar
• Zimmerman MA, Ghobrial RM, Tong MJ, et al. Recurrence of hepatocellular carcinoma following liver transplantation: a review of preoperative and postoperative prognostic indicators. Arch Surg. 2008;143:182–8; discussion 8. doi:10.1001/archsurg.2007.39
   PubMedGoogle Scholar
• Chen LL, Yang L. Regulation of circRNA biogenesis. RNA Biol. 2015;12:381–388. doi:10.1080/15476286.2015.102027125746834
   PubMed Web of Science ®Google Scholar
• Hentze MW, Preiss T. Circular RNAs: splicing’s enigma variations. EMBO J. 2013;32:923–925. doi:10.1038/emboj.2013.5323463100
   PubMed Web of Science ®Google Scholar
• Memczak S, Jens M, Elefsinioti A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 2013;495:333–338. doi:10.1038/nature1192823446348
   PubMed Web of Science ®Google Scholar
• Jeck WR, Sorrentino JA, Wang K, et al. Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA. 2013;19:141–157. doi:10.1261/rna.035667.11223249747
   PubMed Web of Science ®Google Scholar
• Hansen TB, Jensen TI, Clausen BH, et al. Natural RNA circles function as efficient microRNA sponges. Nature. 2013;495:384–388. doi:10.1038/nature1199323446346
   PubMed Web of Science ®Google Scholar
• Chen J, Li Y, Zheng Q, et al. Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer. Cancer Lett. 2017;388:208–219. doi:10.1016/j.canlet.2016.12.00627986464
   PubMed Web of Science ®Google Scholar
• He R, Liu P, Xie X, et al. circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a. J Exp Clin Cancer Res. 2017;36:145. doi:10.1186/s13046-017-0614-129037220
   PubMed Web of Science ®Google Scholar
• Zhang J, Liu H, Hou L, et al. Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression. Mol Cancer. 2017;16:151. doi:10.1186/s12943-017-0719-328893265
   PubMed Web of Science ®Google Scholar
• Li J, Tian H, Pan J, et al. Pecanex functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer. Cancer Lett. 2017;406:36–46. doi:10.1016/j.canlet.2017.07.03028789966
   PubMed Web of Science ®Google Scholar
• Han D, Li J, Wang H, et al. Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression. Hepatology. 2017;66:1151–1164. doi:10.1002/hep.2927028520103
   PubMed Web of Science ®Google Scholar
• Qin M, Liu G, Huo X, et al. Hsa_circ_0001649: a circular RNA and potential novel biomarker for hepatocellular carcinoma. Cancer Biomark. 2016;16:161–169. doi:10.3233/CBM-15055226600397
   PubMed Web of Science ®Google Scholar
• Xu L, Zhang M, Zheng X, Yi P, Lan C, Xu M. The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2017;143:17–27. doi:10.1007/s00432-016-2256-727614453
   PubMed Web of Science ®Google Scholar
• Gilbert TL, Haldeman BA, Mulvihill E, O’Hara PJ. A mammalian homologue of a transcript from the Drosophila pecanex locus. J Neurogenet. 1992;8:181–187. doi:10.3109/016770692090834471460533
   PubMed Web of Science ®Google Scholar
• Yamakawa T, Yamada K, Sasamura T, et al. Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila. Development. 2012;139:558–567. doi:10.1242/dev.07385822190636
   PubMed Web of Science ®Google Scholar
• Wang Y, Cui M, Sun BD, Liu FB, Zhang XD, Ye LH. MiR-506 suppresses proliferation of hepatoma cells through targeting YAP mRNA 3ʹUTR. Acta Pharmacol Sin. 2014;35:1207–1214. doi:10.1038/aps.2014.5925087998
   PubMed Web of Science ®Google Scholar
• Dai W, Huang HL, Hu M, et al. microRNA-506 regulates proliferation, migration and invasion in hepatocellular carcinoma by targeting F-spondin 1 (SPON1). Am J Cancer Res. 2015;5:2697–2707.26609477
   PubMed Web of Science ®Google Scholar
• Deng Q, Xie L, Li H. MiR-506 suppresses cell proliferation and tumor growth by targeting Rho-associated protein kinase 1 in hepatocellular carcinoma. Biochem Biophys Res Commun. 2015;467:921–927. doi:10.1016/j.bbrc.2015.10.04326474697
   PubMed Web of Science ®Google Scholar
• Deng L, Liu H. MicroRNA-506 suppresses growth and metastasis of oral squamous cell carcinoma via targeting GATA6. Int J Clin Exp Med. 2015;8(2 ):1862–1870.25932114
   PubMed Web of Science ®Google Scholar
• Wen SY, Lin Y, Yu YQ, et al. miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer. Oncogene. 2014;34(6 ):717–725. doi:10.1038/onc.2014.924608427
   PubMed Web of Science ®Google Scholar
• Liu G, Sun Y, Ji P, et al. MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol. 2014;233(3 ):308–318. doi:10.1002/path.434824604117
   PubMed Web of Science ®Google Scholar
• Zhang Z, Ma J, Luan G, et al. MiR-506 suppresses tumor proliferation and invasion by targeting FOXQ1 in nasopharyngeal carcinoma. PLoS One. 2015;10(4 ):e0122851. doi:10.1371/journal.pone.012285125856555
   PubMed Web of Science ®Google Scholar
• Yu Z, Zhang Y, Gao N, et al. Overexpression of miR-506 inhibits growth of osteosarcoma through Snail2. Am J Transl Res. 2015;7(12 ):2716.26885269
   PubMed Web of Science ®Google Scholar
• Hua K, Yang W, Song H, et al. Up-regulation of miR-506 inhibits cell growth and disrupt the cell cycle by targeting YAP in breast cancer cells. Int J Clin Exp Med. 2015;8(8 ):12018.26550114
   PubMed Web of Science ®Google Scholar