CCNY Accelerates Cylcin E Expression to Regulate the Proliferation of Laryngeal Carcinoma Cells via MEK/ERK Signaling Pathway

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019;69(1):7–34. doi:10.3322/caac.2155130620402
   PubMed Web of Science ®Google Scholar
• Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–132. doi:10.3322/caac.2133826808342
   PubMed Web of Science ®Google Scholar
• Amemiya K, Shibuya H, Yoshimura R, et al. The risk of radiation-induced cancer in patients with squamous cell carcinoma of the head and neck and its results of treatment. Br J Radiol. 2005;78(935):1028–1033. doi:10.1259/bjr/8635230916249604
   PubMed Web of Science ®Google Scholar
• Siddiqui F, Movsas B. Management of radiation toxicity in head and neck cancers. Semin Radiat Oncol. 2017;27(4):340–349. doi:10.1016/j.semradonc.2017.04.00828865517
   PubMed Web of Science ®Google Scholar
• Xu W, Han D, Hou L, et al. Voice function following CO2 laser microsurgery for precancerous and early-stage glottic carcinoma. Acta Otolaryngol. 2007;127(6):637–641. doi:10.1080/0001648060098777617503234
   PubMed Web of Science ®Google Scholar
• Dias FL, Lima RA, Kligerman J, et al. Therapeutic options in advanced laryngeal cancer: an overview. ORL J Otorhinolaryngol Relat Spec. 2005;67(6):311–318. doi:10.1159/00009004016340243
   PubMedGoogle Scholar
• Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100(1):57–70. doi:10.1016/S0092-8674(00)81683-910647931
   PubMed Web of Science ®Google Scholar
• Arata Y, Takagi H. Quantitative studies for cell-division cycle control. Front Physiol. 2019;10:1022. doi:10.3389/fphys.2019.0102231496950
   PubMed Web of Science ®Google Scholar
• Liu LM, Kolodziejczyk W, Sicinski A. The cell cycle in stem cell proliferation, pluripotency and differentiation. Nat cell Biol, 2019;21(9):1060–1067.31481793
   PubMed Web of Science ®Google Scholar
• Stamatakos M, Palla V, Karaiskos I, et al. Cell cyclins: triggering elements of cancer or not? World J Surg Oncol. 2010;8:111. doi:10.1186/1477-7819-8-11121176227
   PubMed Web of Science ®Google Scholar
• Liu D, Finley RL Jr. Cyclin Y is a novel conserved cyclin essential for development in Drosophila. Genetics. 2010;184(4):1025–1035. doi:10.1534/genetics.110.11401720100936
   PubMed Web of Science ®Google Scholar
• Liu D, Guest S, Finley RL Jr. Why cyclin Y? A highly conserved cyclin with essential functions. Fly. 2010;4(4):278–282. doi:10.4161/fly.4.4.1288120699655
   PubMed Web of Science ®Google Scholar
• Ying-Tao Z, Yi-Ping G, Lu-Sheng S, et al. Proteomic analysis of differentially expressed proteins between metastatic and non-metastatic human colorectal carcinoma cell lines. Eur J Gastroenterol Hepatol. 2005;17(7):725–732. doi:10.1097/00042737-200507000-0000615947549
   PubMed Web of Science ®Google Scholar
• Xu Y, Wang Z, Wang J, et al. Lentivirus-mediated knockdown of cyclin Y (CCNY) inhibits glioma cell proliferation. Oncol Res. 2010;18(8):359–364. doi:10.3727/096504010X1264442232058220441050
   PubMed Web of Science ®Google Scholar
• Yan F, Wang X, Zhu M, et al. RNAi-mediated downregulation of cyclin Y to attenuate human breast cancer cell growth. Oncol Rep. 2016;36(5):2793–2799. doi:10.3892/or.2016.512627666310
   PubMed Web of Science ®Google Scholar
• Yue W, Zhao X, Zhang L, et al. Overexpression of cyclin Y in non-small cell lung cancer is associated with cancer cell proliferation. Sci China Life Sci. 2010;53(4):511–516. doi:10.1007/s11427-010-0090-820596919
   PubMed Web of Science ®Google Scholar
• Yue W, Zhao X, Zhang L, et al. Cell cycle protein cyclin Y is associated with human non-small-cell lung cancer proliferation and tumorigenesis. Clin Lung Cancer. 2011;12(1):43–50. doi:10.3816/CLC.2011.n.00621273179
   PubMed Web of Science ®Google Scholar
• Liu H, Shi H, Fan Q, et al. Cyclin Y regulates the proliferation, migration, and invasion of ovarian cancer cells via Wnt signaling pathway. Tumour Biol. 2016;37(8):10161–10175. doi:10.1007/s13277-016-4818-326831658
   PubMedGoogle Scholar
• Shi K, Ru Q, Zhang C, et al. Cyclin Y modulates the proliferation, invasion, and metastasis of hepatocellular carcinoma cells. Med Sci Monit. 2018;24:1642–1653. doi:10.12659/MSM.90607529557391
   PubMed Web of Science ®Google Scholar
• Jiang M, Gao Y, Yang T, et al. Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1. FEBS Lett. 2009;583(13):2171–2178. doi:10.1016/j.febslet.2009.06.01019524571
   PubMed Web of Science ®Google Scholar
• Li S, Song W, Jiang M, et al. Phosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradation. FEBS Lett. 2014;588(11):1989–1996. doi:10.1016/j.febslet.2014.04.01924794231
   PubMed Web of Science ®Google Scholar
• Hernandez-Ortega S, Sanchez-Botet A, Quandt E, et al. Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex. Exp Mol Med. 2019;51(4):44. doi:10.1038/s12276-019-0242-2
   PubMed Web of Science ®Google Scholar
• Si Y, Liu J, Shen H, et al. Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell. J Cell Mol Med. 2019;23(2):1095–1105. doi:10.1111/jcmm.1401030411496
   PubMed Web of Science ®Google Scholar
• Davidson G, Shen J, Huang YL, et al. Cell cycle control of wnt receptor activation. Dev Cell. 2009;17(6):788–799. doi:10.1016/j.devcel.2009.11.00620059949
   PubMed Web of Science ®Google Scholar
• Wang X, Jia Y, Fei C, et al. Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation. J Biol Chem. 2016;291(51):26427–26434. doi:10.1074/jbc.M116.74460727821587
   PubMed Web of Science ®Google Scholar
• Sun T, Co NN, Wong N. PFTK1 interacts with cyclin Y to activate non-canonical Wnt signaling in hepatocellular carcinoma. Biochem Biophys Res Commun. 2014;449(1):163–168. doi:10.1016/j.bbrc.2014.05.00224824184
   PubMed Web of Science ®Google Scholar
• Yaeger R, Corcoran RB. Targeting alterations in the RAF-MEK pathway. Cancer Discov. 2019;9(3):329–341. doi:10.1158/2159-8290.CD-18-132130770389
   PubMed Web of Science ®Google Scholar
• McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta. 2007;1773(8):1263–1284. doi:10.1016/j.bbamcr.2006.10.00117126425
   PubMed Web of Science ®Google Scholar
• Woods D, Parry D, Cherwinski H, et al. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol. 1997;17(9):5598–5611. doi:10.1128/MCB.17.9.55989271435
   PubMed Web of Science ®Google Scholar
• Ghule PN, Seward DJ, Fritz AJ, et al. Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition. J Cell Physiol. 2018;233(10):6406–6413. doi:10.1002/jcp.2674129744889
   PubMed Web of Science ®Google Scholar